Coiled coil protein origami: from modular design principles towards biotechnological applications
Lapenta, Fabio, Aupi, Jana, Strmšek, iga, Jerala, Roman
Published in Chemical Society reviews (21.05.2018)
Published in Chemical Society reviews (21.05.2018)
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Journal Article
Design of fast proteolysis-based signaling and logic circuits in mammalian cells
Fink, Tina, Lonzarić, Jan, Praznik, Arne, Plaper, Tjaša, Merljak, Estera, Leben, Katja, Jerala, Nina, Lebar, Tina, Strmšek, Žiga, Lapenta, Fabio, Benčina, Mojca, Jerala, Roman
Published in Nature chemical biology (01.02.2019)
Published in Nature chemical biology (01.02.2019)
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Journal Article
Design of split superantigen fusion proteins for cancer immunotherapy
Golob-Urbanc, Anja, Rajčević, Uroš, Strmšek, Žiga, Jerala, Roman
Published in The Journal of biological chemistry (19.04.2019)
Published in The Journal of biological chemistry (19.04.2019)
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Journal Article
Structural polymorphism of coiled‐coils from the stalk domain of SARS‐CoV‐2 spike protein
Živič, Zala, Strmšek, Žiga, Novinec, Marko, Lah, Jurij, Hadži, San
Published in The FASEB Journal (01.03.2022)
Published in The FASEB Journal (01.03.2022)
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Web Resource
A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures
Majerle, Andreja, Hadži, San, Aupič, Jana, Satler, Tadej, Lapenta, Fabio, Strmšek, Žiga, Lah, Jurij, Loris, Remy, Jerala, Roman
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2021)
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Journal Article
Binding of the transcription activator-like effector augments transcriptional regulation by another transcription factor
Leben, Katja, Strmšek, Žiga, Lebar, Tina, Verbič, Anže, Dragovan, Matej, Omersa, Neža, Anderluh, Gregor, Jerala, Roman
Published in Nucleic acids research (24.06.2022)
Published in Nucleic acids research (24.06.2022)
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Journal Article
Selective inhibition of NLRP3 inflammasome by designed peptide originating from ASC
Sušjan, Petra, Lainšček, Duško, Strmšek, Žiga, Hodnik, Vesna, Anderluh, Gregor, Hafner-Bratkovič, Iva
Published in The FASEB journal (01.08.2020)
Published in The FASEB journal (01.08.2020)
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Journal Article
Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo
Ljubetič, Ajasja, Lapenta, Fabio, Gradišar, Helena, Drobnak, Igor, Aupič, Jana, Strmšek, Žiga, Lainšček, Duško, Hafner-Bratkovič, Iva, Majerle, Andreja, Krivec, Nuša, Benčina, Mojca, Pisanski, Tomaž, Veličković, Tanja Ćirković, Round, Adam, Carazo, José María, Melero, Roberto, Jerala, Roman
Published in Nature biotechnology (01.11.2017)
Published in Nature biotechnology (01.11.2017)
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Journal Article
Towards designing new nano-scale protein architectures
Aupič, Jana, Lapenta, Fabio, Strmšek, Žiga, Jerala, Roman
Published in Essays in biochemistry (30.11.2016)
Published in Essays in biochemistry (30.11.2016)
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Journal Article
EMBO Beyond Biology: Connecting peptide, protein, and DNA design with systems chemistry
Dave, Dhwanit, Massarano, Tlalit, Katzir, Itai, Strmšek, Žiga, Ljubetič, Ajasja, Sementa, Deborah
Published in Chem (10.02.2022)
Published in Chem (10.02.2022)
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Journal Article
A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response
Lainšček, Duško, Fink, Tina, Forstnerič, Vida, Hafner-Bratkovič, Iva, Orehek, Sara, Strmšek, Žiga, Manček-Keber, Mateja, Pečan, Peter, Esih, Hana, Malenšek, Špela, Aupič, Jana, Dekleva, Petra, Plaper, Tjaša, Vidmar, Sara, Kadunc, Lucija, Benčina, Mojca, Omersa, Neža, Anderluh, Gregor, Pojer, Florence, Lau, Kelvin, Hacker, David, Correia, Bruno E, Peterhoff, David, Wagner, Ralf, Bergant, Valter, Herrmann, Alexander, Pichlmair, Andreas, Jerala, Roman
Published in Vaccines (Basel) (27.04.2021)
Published in Vaccines (Basel) (27.04.2021)
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Journal Article
Self-assembly and regulation of protein cages from pre-organised coiled-coil modules
Lapenta, Fabio, Aupič, Jana, Vezzoli, Marco, Strmšek, Žiga, Da Vela, Stefano, Svergun, Dmitri I, Carazo, José María, Melero, Roberto, Jerala, Roman
Published in Nature communications (11.02.2021)
Published in Nature communications (11.02.2021)
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Journal Article
Designed folding pathway of modular coiled-coil-based proteins
Aupič, Jana, Strmšek, Žiga, Lapenta, Fabio, Pahovnik, David, Pisanski, Tomaž, Drobnak, Igor, Ljubetič, Ajasja, Jerala, Roman
Published in Nature communications (11.02.2021)
Published in Nature communications (11.02.2021)
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Journal Article
Author Correction: Self-assembly and regulation of protein cages from pre-organised coiled-coil modules
Lapenta, Fabio, Aupič, Jana, Vezzoli, Marco, Strmšek, Žiga, Da Vela, Stefano, Svergun, Dmitri I, Carazo, José María, Melero, Roberto, Jerala, Roman
Published in Nature communications (16.03.2021)
Published in Nature communications (16.03.2021)
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Journal Article
Vaccines based on an antigen protein fused to a nanostructuring scaffold
STRMSEK Ziga, ESIH Hana, OREHEK Sara, MANCEK Mateja, PLAPER Tjasa, FINK Tina, JERALA Roman, LAINSCEK Dusko, AUPIC Jana, HAFNER Iva, FORSTNERIC Vida, BENCINA Mojca, PECAN Peter, MALENSEK Spela, DEKLEVA Petra
Year of Publication 28.02.2022
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Year of Publication 28.02.2022
Patent
Immune response to vaccine candidates based on different types of nanoscaffolded RBD domain of the SARS-CoV-2 spike protein
Lainscek, Dusko, Fink, Tina, stneric, Vida, Hafner-Bratkovic, Iva, Orehek, Sara, Strmsek, Ziga, Keber, Mateja Mancek, Pecan, Peter, Esih, Hana, Malensek, Spela, Aupic, Jana, Dekleva, Petra, Plaper, Tjasa, Vidmar, Sara, Kadunc, Lucija, Bencina, Mojca, Pojer, Florence, Lau, Kelvin, Hacker, David, Correia, Bruno, Peterhoff, David, Wagner, Ralf, Jerala, Roman
Published in bioRxiv (28.08.2020)
Published in bioRxiv (28.08.2020)
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Paper