A review of Formulations of Commercially Available Antibodies
Strickley, Robert G., Lambert, William J.
Published in Journal of pharmaceutical sciences (01.07.2021)
Published in Journal of pharmaceutical sciences (01.07.2021)
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Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1‑f][triazin-4-amino] Adenine C‑Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses
Siegel, Dustin, Hui, Hon C, Doerffler, Edward, Clarke, Michael O, Chun, Kwon, Zhang, Lijun, Neville, Sean, Carra, Ernest, Lew, Willard, Ross, Bruce, Wang, Queenie, Wolfe, Lydia, Jordan, Robert, Soloveva, Veronica, Knox, John, Perry, Jason, Perron, Michel, Stray, Kirsten M, Barauskas, Ona, Feng, Joy Y, Xu, Yili, Lee, Gary, Rheingold, Arnold L, Ray, Adrian S, Bannister, Roy, Strickley, Robert, Swaminathan, Swami, Lee, William A, Bavari, Sina, Cihlar, Tomas, Lo, Michael K, Warren, Travis K, Mackman, Richard L
Published in Journal of Medicinal Chemistry (09.03.2017)
Published in Journal of Medicinal Chemistry (09.03.2017)
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Pediatric Drugs-A Review of Commercially Available Oral Formulations
Strickley, Robert G., Iwata, Quynh, Wu, Sylvia, Dahl, Terrence C.
Published in Journal of pharmaceutical sciences (01.05.2008)
Published in Journal of pharmaceutical sciences (01.05.2008)
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Discovery of an Oral Respiratory Syncytial Virus (RSV) Fusion Inhibitor (GS-5806) and Clinical Proof of Concept in a Human RSV Challenge Study
Mackman, Richard L, Sangi, Michael, Sperandio, David, Parrish, Jay P, Eisenberg, Eugene, Perron, Michel, Hui, Hon, Zhang, Lijun, Siegel, Dustin, Yang, Hai, Saunders, Oliver, Boojamra, Constantine, Lee, Gary, Samuel, Dharmaraj, Babaoglu, Kerim, Carey, Anne, Gilbert, Brian E, Piedra, Pedro A, Strickley, Robert, Iwata, Quynh, Hayes, Jaclyn, Stray, Kirsten, Kinkade, April, Theodore, Dorothy, Jordan, Robert, Desai, Manoj, Cihlar, Tomas
Published in Journal of medicinal chemistry (26.02.2015)
Published in Journal of medicinal chemistry (26.02.2015)
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Cobicistat (GS-9350): A Potent and Selective Inhibitor of Human CYP3A as a Novel Pharmacoenhancer
Xu, Lianhong, Liu, Hongtao, Murray, Bernard P, Callebaut, Christian, Lee, Melody S, Hong, Allen, Strickley, Robert G, Tsai, Luong K, Stray, Kirsten M, Wang, Yujin, Rhodes, Gerry R, Desai, Manoj C
Published in ACS medicinal chemistry letters (12.08.2010)
Published in ACS medicinal chemistry letters (12.08.2010)
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Antiviral Efficacy of a Respiratory Syncytial Virus (RSV) Fusion Inhibitor in a Bovine Model of RSV Infection
Jordan, Robert, Shao, Matt, Mackman, Richard L, Perron, Michel, Cihlar, Tomas, Lewis, Sandy A, Eisenberg, Eugene J, Carey, Anne, Strickley, Robert G, Chien, Jason W, Anderson, Mark L, McEligot, Heather A, Behrens, Nicole E, Gershwin, Laurel J
Published in Antimicrobial agents and chemotherapy (01.08.2015)
Published in Antimicrobial agents and chemotherapy (01.08.2015)
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Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers. Part II: P2/P3 region and discovery of cobicistat (GS-9350)
Xu, Lianhong, Liu, Hongtao, Hong, Allen, Vivian, Randy, Murray, Bernard P., Callebaut, Christian, Choi, You-Chul, Lee, Melody S., Chau, Jennifer, Tsai, Luong K., Stray, Kirsten M., Strickley, Robert G., Wang, Jianhong, Tong, Leah, Swaminathan, Swami, Rhodes, Gerry R., Desai, Manoj C.
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
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Optimization of Pharmacokinetics through Manipulation of Physicochemical Properties in a Series of HCV Inhibitors
Lazerwith, Scott E, Bahador, Gina, Canales, Eda, Cheng, Guofeng, Chong, Lee, Clarke, Michael O, Doerffler, Edward, Eisenberg, Eugene J, Hayes, Jaclyn, Lu, Bing, Liu, Qi, Matles, Mike, Mertzman, Michael, Mitchell, Michael L, Morganelli, Philip, Murray, Bernard P, Robinson, Margaret, Strickley, Robert G, Tessler, Megan, Tirunagari, Neeraj, Wang, Jianhong, Wang, Yujin, Zhang, Jennifer R, Zheng, Xubin, Zhong, Weidong, Watkins, William J
Published in ACS medicinal chemistry letters (13.10.2011)
Published in ACS medicinal chemistry letters (13.10.2011)
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Discovery of GS-8374, a potent human immunodeficiency virus type 1 protease inhibitor with a superior resistance profile
He, Gong-Xing, Yang, Zheng-Yu, Williams, Matthew, Callebaut, Christian, Cihlar, Tomas, Murray, Bernard P., Yang, Chris, Mitchell, Michael L., Liu, Hongtao, Wang, Jianying, Arimilli, Murty, Eisenberg, Eugene, Stray, Kirsten M., Tsai, Luong K., Hatada, Marcos, Chen, Xiaowu, Chen, James M., Wang, Yujin, Lee, Melody S., Strickley, Robert G., Iwata, Quynh, Zheng, Xubin, Kim, Choung U., Swaminathan, Swami, Desai, Manoj C., Lee, William A., Xu, Lianhong
Published in MedChemComm (01.11.2011)
Published in MedChemComm (01.11.2011)
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Journal Article
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo(2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses
Siegel, Dustin, Hui, Hon C., Doerffler, Edward, Clarke, Michael O., Chun, Kwon, Zhang, Lijun, Neville, Sean, Carra, Ernest, Lew, Willard, Ross, Bruce, Wang, Queenie, Wolfe, Lydia, Jordan, Robert, Soloveva, Veronica, Knox, John, Perry, Jason, Perron, Michel, Stray, Kirsten M., Barauskas, Ona, Feng, Joy Y., Xu, Yili, Lee, Gary, Rheingold, Arnold L., Ray, Adrian S., Bannister, Roy, Strickley, Robert, Swaminathan, Swami, Lee, William A., Bavari, Sina, Cihlar, Tomas, Lo, Michael K., Warren, Travis K., Mackman, Richard L.
Published in Journal of medicinal chemistry (09.03.2017)
Published in Journal of medicinal chemistry (09.03.2017)
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Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys
Warren, Travis K., Jordan, Robert, Lo, Michael K., Ray, Adrian S., Mackman, Richard L., Soloveva, Veronica, Siegel, Dustin, Perron, Michel, Bannister, Roy, Hui, Hon C., Larson, Nate, Strickley, Robert, Wells, Jay, Stuthman, Kelly S., Van Tongeren, Sean A., Garza, Nicole L., Donnelly, Ginger, Shurtleff, Amy C., Retterer, Cary J., Gharaibeh, Dima, Zamani, Rouzbeh, Kenny, Tara, Eaton, Brett P., Grimes, Elizabeth, Welch, Lisa S., Gomba, Laura, Wilhelmsen, Catherine L., Nichols, Donald K., Nuss, Jonathan E., Nagle, Elyse R., Kugelman, Jeffrey R., Palacios, Gustavo, Doerffler, Edward, Neville, Sean, Carra, Ernest, Clarke, Michael O., Zhang, Lijun, Lew, Willard, Ross, Bruce, Wang, Queenie, Chun, Kwon, Wolfe, Lydia, Babusis, Darius, Park, Yeojin, Stray, Kirsten M., Trancheva, Iva, Feng, Joy Y., Barauskas, Ona, Xu, Yili, Wong, Pamela, Braun, Molly R., Flint, Mike, McMullan, Laura K., Chen, Shan-Shan, Fearns, Rachel, Swaminathan, Swami, Mayers, Douglas L., Spiropoulou, Christina F., Lee, William A., Nichol, Stuart T., Cihlar, Tomas, Bavari, Sina
Published in Nature (London) (17.03.2016)
Published in Nature (London) (17.03.2016)
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From paediatric formulations development to access: Advances made and remaining challenges
Litalien, Catherine, Bérubé, Sophie, Tuleu, Catherine, Gilpin, Andrea, Landry, Émilie Kate, Valentin, Marie, Strickley, Robert, Turner, Mark A.
Published in British journal of clinical pharmacology (01.10.2022)
Published in British journal of clinical pharmacology (01.10.2022)
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Design and Synthesis of Tri-Ring P3 Benzamide-Containing Aminonitriles as Potent, Selective, Orally Effective Inhibitors of Cathepsin K
Palmer, James T, Bryant, Clifford, Wang, Dan-Xiong, Davis, Dana E, Setti, Eduardo L, Rydzewski, Robert M, Venkatraman, Shankar, Tian, Zong-Qiang, Burrill, Leland C, Mendonca, Rohan V, Springman, Eric, McCarter, John, Chung, Tobee, Cheung, Harry, Janc, James W, McGrath, Mary, Somoza, John R, Enriquez, Philip, Yu, Z. Walter, Strickley, Robert M, Liu, Liang, Venuti, Michael C, Percival, M. David, Falgueyret, Jean-Pierre, Prasit, Peppi, Oballa, Renata, Riendeau, Denis, Young, Robert N, Wesolowski, Gregg, Rodan, Sevgi B, Johnson, Colena, Kimmel, Donald B, Rodan, Gideon
Published in Journal of medicinal chemistry (01.12.2005)
Published in Journal of medicinal chemistry (01.12.2005)
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Solid-state Stability of Human Insulin II. Effect of Water on Reactive Intermediate Partitioning in Lyophiles from pH 2–5 Solutions: Stabilization Against Covalent Dimer Formation
Strickley, Robert G., Anderson, Bradley D.
Published in Journal of pharmaceutical sciences (01.06.1997)
Published in Journal of pharmaceutical sciences (01.06.1997)
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Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late I Nai), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties
Zablocki, Jeff A, Elzein, Elfatih, Li, Xiaofen, Koltun, Dmitry O, Parkhill, Eric Q, Kobayashi, Tetsuya, Martinez, Ruben, Corkey, Britton, Jiang, Haibo, Perry, Thao, Kalla, Rao, Notte, Gregory T, Saunders, Oliver, Graupe, Michael, Lu, Yafan, Venkataramani, Chandru, Guerrero, Juan, Perry, Jason, Osier, Mark, Strickley, Robert, Liu, Gongxin, Wang, Wei-Qun, Hu, Lufei, Li, Xiao-Jun, El-Bizri, Nesrine, Hirakawa, Ryoko, Kahlig, Kris, Xie, Cheng, Li, Cindy Hong, Dhalla, Arvinder K, Rajamani, Sridharan, Mollova, Nevena, Soohoo, Daniel, Lepist, Eve-Irene, Murray, Bernard, Rhodes, Gerry, Belardinelli, Luiz, Desai, Manoj C
Published in Journal of medicinal chemistry (13.10.2016)
Published in Journal of medicinal chemistry (13.10.2016)
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