Methylation of Human MicroRNA Genes in Normal and Neoplastic Cells
Weber, Barbara, Stresemann, Carlo, Brueckner, Bodo, Lyko, Frank
Published in Cell cycle (Georgetown, Tex.) (02.05.2007)
Published in Cell cycle (Georgetown, Tex.) (02.05.2007)
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Journal Article
EZH2 Inhibition Blocks Multiple Myeloma Cell Growth through Upregulation of Epithelial Tumor Suppressor Genes
Hernando, Henar, Gelato, Kathy A, Lesche, Ralf, Beckmann, Georg, Koehr, Silke, Otto, Saskia, Steigemann, Patrick, Stresemann, Carlo
Published in Molecular cancer therapeutics (01.02.2016)
Published in Molecular cancer therapeutics (01.02.2016)
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Journal Article
Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines
STRESEMANN, Carlo, BRUECKNER, Bodo, MUSCH, Tanja, STOPPER, Helga, LYKO, Frank
Published in Cancer research (Chicago, Ill.) (01.03.2006)
Published in Cancer research (Chicago, Ill.) (01.03.2006)
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Journal Article
Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer
Reynoird, Nicolas, Mazur, Pawel K, Stellfeld, Timo, Flores, Natasha M, Lofgren, Shane M, Carlson, Scott M, Brambilla, Elisabeth, Hainaut, Pierre, Kaznowska, Ewa B, Arrowsmith, Cheryl H, Khatri, Purvesh, Stresemann, Carlo, Gozani, Or, Sage, Julien
Published in Genes & development (01.04.2016)
Published in Genes & development (01.04.2016)
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Journal Article
A miniaturized mode-of-action profiling platform enables high throughput characterization of the molecular and cellular dynamics of EZH2 inhibition
Falkenstern, Lilia, Georgi, Victoria, Bunse, Stefanie, Badock, Volker, Husemann, Manfred, Roehn, Ulrike, Stellfeld, Timo, Fitzgerald, Mark, Ferrara, Steven, Stöckigt, Detlef, Stresemann, Carlo, Hartung, Ingo V., Fernández-Montalván, Amaury
Published in Scientific reports (19.01.2024)
Published in Scientific reports (19.01.2024)
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Journal Article
Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in Vivo Probe (BAY-598) for the Protein Lysine Methyltransferase SMYD2
Eggert, Erik, Hillig, Roman C, Koehr, Silke, Stöckigt, Detlef, Weiske, Jörg, Barak, Naomi, Mowat, Jeffrey, Brumby, Thomas, Christ, Clara D, ter Laak, Antonius, Lang, Tina, Fernandez-Montalvan, Amaury E, Badock, Volker, Weinmann, Hilmar, Hartung, Ingo V, Barsyte-Lovejoy, Dalia, Szewczyk, Magdalena, Kennedy, Steven, Li, Fengling, Vedadi, Masoud, Brown, Peter J, Santhakumar, Vijayaratnam, Arrowsmith, Cheryl H, Stellfeld, Timo, Stresemann, Carlo
Published in Journal of medicinal chemistry (26.05.2016)
Published in Journal of medicinal chemistry (26.05.2016)
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Journal Article
Functional diversity of inhibitors tackling the differentiation blockage of MLL-rearranged leukemia
Brzezinka, Krzysztof, Nevedomskaya, Ekaterina, Lesche, Ralf, Steckel, Michael, Eheim, Ashley L, Haegebarth, Andrea, Stresemann, Carlo
Published in Journal of hematology and oncology (28.06.2019)
Published in Journal of hematology and oncology (28.06.2019)
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Journal Article
Azacytidine causes complex DNA methylation responses in myeloid leukemia
Stresemann, Carlo, Bokelmann, Imke, Mahlknecht, Ulrich, Lyko, Frank
Published in Molecular cancer therapeutics (01.09.2008)
Published in Molecular cancer therapeutics (01.09.2008)
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Journal Article
Identification of Small Molecules that Modulate Mutant p53 Condensation
Lemos, Clara, Schulze, Luise, Weiske, Joerg, Meyer, Hanna, Braeuer, Nico, Barak, Naomi, Eberspächer, Uwe, Werbeck, Nicolas, Stresemann, Carlo, Lange, Martin, Lesche, Ralf, Zablowsky, Nina, Juenemann, Katrin, Kamburov, Atanas, Luh, Laura Martina, Leissing, Thomas Markus, Mortier, Jeremie, Steckel, Michael, Steuber, Holger, Eis, Knut, Eheim, Ashley, Steigemann, Patrick
Published in iScience (25.09.2020)
Published in iScience (25.09.2020)
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Journal Article
Human concentrative nucleoside transporter 1-mediated uptake of 5-azacytidine enhances DNA demethylation
Rius, Maria, Stresemann, Carlo, Keller, Daniela, Brom, Manuela, Schirrmacher, Esther, Keppler, Dietrich, Lyko, Frank
Published in Molecular cancer therapeutics (01.01.2009)
Published in Molecular cancer therapeutics (01.01.2009)
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Journal Article
The human let-7a-3 locus contains an epigenetically regulated MicroRNA gene with oncogenic function
BRUECKNER, Bodo, STRESEMANN, Carlo, KUNER, Ruprecht, MUND, Cora, MUSCH, Tanja, MEISTER, Michael, SFÜLTMANN, Holger, LYKO, Frank
Published in Cancer research (Chicago, Ill.) (15.02.2007)
Published in Cancer research (Chicago, Ill.) (15.02.2007)
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Journal Article
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis
Alborzinia, Hamed, Flórez, Andrés F, Kreth, Sina, Brückner, Lena M, Yildiz, Umut, Gartlgruber, Moritz, Odoni, Dorett I, Poschet, Gernot, Garbowicz, Karolina, Shao, Chunxuan, Klein, Corinna, Meier, Jasmin, Zeisberger, Petra, Nadler-Holly, Michal, Ziehm, Matthias, Paul, Franziska, Burhenne, Jürgen, Bell, Emma, Shaikhkarami, Marjan, Würth, Roberto, Stainczyk, Sabine A, Wecht, Elisa M, Kreth, Jochen, Büttner, Michael, Ishaque, Naveed, Schlesner, Matthias, Nicke, Barbara, Stresemann, Carlo, Llamazares-Prada, María, Reiling, Jan H, Fischer, Matthias, Amit, Ido, Selbach, Matthias, Herrmann, Carl, Wölfl, Stefan, Henrich, Kai-Oliver, Höfer, Thomas, Trumpp, Andreas, Westermann, Frank
Published in Nature cancer (01.04.2022)
Published in Nature cancer (01.04.2022)
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Abstract C079: Comprehensive immunophenotypic profiling sheds light on the dynamic interplay between immune cells in the 4T1 breast cancer model upon anti-PD1 and anti-CTLA4 immunotherapy
Nikolaou, Christos, Heller, Simon, Kaulfuss, Stefan, Stresemann, Carlo, Eichten, Alexandra, von Ahsen, Oliver, Lange, Martin
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
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Journal Article
Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
Graham, Keith, Lienau, Philip, Bader, Benjamin, Prechtl, Stefan, Naujoks, Jan, Lesche, Ralf, Weiske, Joerg, Kuehnlenz, Julia, Brzezinka, Krzysztof, Potze, Lisette, Zanconato, Francesca, Nicke, Barbara, Montebaur, Anna, Bone, Wilhelm, Golfier, Sven, Kaulfuss, Stefan, Kopitz, Charlotte, Pilari, Sabine, Steuber, Holger, Hayat, Sikander, Kamburov, Atanas, Steffen, Andreas, Schlicker, Andreas, Buchgraber, Philipp, Braeuer, Nico, Font, Nuria Aiguabella, Heinrich, Tobias, Kuhnke, Lara, Nowak-Reppel, Katrin, Stresemann, Carlo, Steigemann, Patrick, Walter, Annette O., Blotta, Simona, Ocker, Matthias, Lakner, Ashley, von Nussbaum, Franz, Mumberg, Dominik, Eis, Knut, Piccolo, Stefano, Lange, Martin
Published in Cell chemical biology (18.07.2024)
Published in Cell chemical biology (18.07.2024)
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Journal Article
Characterization of the Menin-MLL Interaction as Therapeutic Cancer Target
Brzezinka, Krzysztof, Nevedomskaya, Ekaterina, Lesche, Ralf, Haegebarth, Andrea, Ter Laak, Antonius, Fernández-Montalván, Amaury E, Eberspaecher, Uwe, Werbeck, Nicolas D, Moenning, Ursula, Siegel, Stephan, Haendler, Bernard, Eheim, Ashley L, Stresemann, Carlo
Published in Cancers (14.01.2020)
Published in Cancers (14.01.2020)
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Journal Article
Abstract 4973: MYCN mediates cysteine addiction and sensitizes to ferroptosis in cancer cells
Westermann, Frank, Alborzinia, Hamed, Gogolin, Sina, Flórez, Andrés F., Brückner, Lena M., Gartlgruber, Moritz, Hartlieb, Sabine, Dreidax, Daniel, Nadler-Holly, Michal, Ziehm, Matthias, Shao, Chunxuan, Selbach, Matthias, Stresemann, Carlo, Poschet, Gernot, Nicke, Barbara, Wölfl, Stefan, Henrich, Kai O., Höfer, Thomas
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Quantification of Histone H3 Lys27 Trimethylation (H3K27me3) by High-Throughput Microscopy Enables Cellular Large-Scale Screening for Small-Molecule EZH2 Inhibitors
Luense, Svenja, Denner, Philip, Fernández-Montalván, Amaury, Hartung, Ingo, Husemann, Manfred, Stresemann, Carlo, Prechtl, Stefan
Published in Journal of biomolecular screening (01.02.2015)
Published in Journal of biomolecular screening (01.02.2015)
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