Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial
Long, Georgina V, Dr, Trefzer, Uwe, MD, Davies, Michael A, MD, Kefford, Richard F, Prof, Ascierto, Paolo A, MD, Chapman, Paul B, MD, Puzanov, Igor, MD, Hauschild, Axel, MD, Robert, Caroline, PhD, Algazi, Alain, MD, Mortier, Laurent, Prof, Tawbi, Hussein, PhD, Wilhelm, Tabea, MD, Zimmer, Lisa, MD, Switzky, Julie, MSN, Swann, Suzanne, PhD, Martin, Anne-Marie, PhD, Guckert, Mary, MSN, Goodman, Vicki, MD, Streit, Michael, MD, Kirkwood, John M, Prof, Schadendorf, Dirk, Prof
Published in The lancet oncology (01.11.2012)
Published in The lancet oncology (01.11.2012)
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A pan-cancer organoid platform for precision medicine
Larsen, Brian M., Kannan, Madhavi, Langer, Lee F., Leibowitz, Benjamin D., Bentaieb, Aicha, Cancino, Andrea, Dolgalev, Igor, Drummond, Bridgette E., Dry, Jonathan R., Ho, Chi-Sing, Khullar, Gaurav, Krantz, Benjamin A., Mapes, Brandon, McKinnon, Kelly E., Metti, Jessica, Perera, Jason F., Rand, Tim A., Sanchez-Freire, Veronica, Shaxted, Jenna M., Stein, Michelle M., Streit, Michael A., Tan, Yi-Hung Carol, Zhang, Yilin, Zhao, Ende, Venkataraman, Jagadish, Stumpe, Martin C., Borgia, Jeffrey A., Masood, Ashiq, Catenacci, Daniel V.T., Mathews, Jeremy V., Gursel, Demirkan B., Wei, Jian-Jun, Welling, Theodore H., Simeone, Diane M., White, Kevin P., Khan, Aly A., Igartua, Catherine, Salahudeen, Ameen A.
Published in Cell reports (Cambridge) (27.07.2021)
Published in Cell reports (Cambridge) (27.07.2021)
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Organizing a COVID-19 triage unit: a Swiss perspective
Peros, Georgios, Gronki, Ferda, Molitor, Nadine, Streit, Michael, Sugimoto, Kiyoshi, Karrer, Urs, Lunger, Fabian, Adamina, Michel, Breitenstein, Stefan, Lamdark, Tenzin
Published in Emerging microbes & infections (01.01.2020)
Published in Emerging microbes & infections (01.01.2020)
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Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4
Echtermeyer, F, Streit, M, Wilcox-Adelman, S, Saoncella, S, Denhez, F, Detmar, M, Goetinck, P
Published in The Journal of clinical investigation (01.01.2001)
Published in The Journal of clinical investigation (01.01.2001)
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The α1β1 and α2β1integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis
SENGER, Donald R, PERRUZZI, Carole A, STREIT, Michael, KOTELIANSKY, Victor E, DE FOUGEROLLES, Antonin R, DETMAR, Michael
Published in The American journal of pathology (2002)
Published in The American journal of pathology (2002)
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Thrombospondin-2 overexpression in the skin of transgenic mice reduces the susceptibility to chemically induced multistep skin carcinogenesis
Kunstfeld, Rainer, Hawighorst, Thomas, Streit, Michael, Hong, Young-Kwon, Nguyen, Lynh, Brown, Lawrence F, Detmar, Michael
Published in Journal of dermatological science (01.05.2014)
Published in Journal of dermatological science (01.05.2014)
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Thrombospondin-2: A Potent Endogenous Inhibitor of Tumor Growth and Angiogenesis
Streit, Michael, Riccardi, Lucia, Velasco, Paula, Brown, Lawrence F., Hawighorst, Thomas, Bornstein, Paul, Detmar, Michael
Published in Proceedings of the National Academy of Sciences - PNAS (21.12.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (21.12.1999)
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Overexpression of Thrombospondin-1 Decreases Angiogenesis and Inhibits the Growth of Human Cutaneous Squamous Cell Carcinomas
Streit, Michael, Velasco, Paula, Brown, Lawrence F., Skobe, Mihaela, Richard, Lisa, Riccardi, Lucia, Lawler, Jack, Detmar, Michael
Published in The American journal of pathology (01.08.1999)
Published in The American journal of pathology (01.08.1999)
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Activation of the Tie2 Receptor by Angiopoietin-1 Enhances Tumor Vessel Maturation and Impairs Squamous Cell Carcinoma Growth
Hawighorst, Thomas, Skobe, Mihaela, Streit, Michael, Hong, Young-Kwon, Velasco, Paula, Brown, Lawrence F., Riccardi, Lucia, Lange-Asschenfeldt, Bernhard, Detmar, Michael
Published in The American journal of pathology (01.04.2002)
Published in The American journal of pathology (01.04.2002)
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Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants
Zhang, Siwei, Zhang, Hanwen, Zhou, Yifan, Qiao, Min, Zhao, Siming, Kozlova, Alena, Shi, Jianxin, Sanders, Alan R, Wang, Gao, Luo, Kaixuan, Sengupta, Subhajit, West, Siobhan, Qian, Sheng, Streit, Michael, Avramopoulos, Dimitrios, Cowan, Chad A, Chen, Mengjie, Pang, Zhiping P, Gejman, Pablo V, He, Xin, Duan, Jubao
Published in Science (American Association for the Advancement of Science) (31.07.2020)
Published in Science (American Association for the Advancement of Science) (31.07.2020)
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Interim results of phase II study BRF113928 of dabrafenib in BRAF V600E mutation–positive non-small cell lung cancer (NSCLC) patients
Planchard, David, Mazieres, Julien, Riely, Gregory J., Rudin, Charles M., Barlesi, Fabrice, Quoix, Elisabeth A., Souquet, Pierre Jean, Socinski, Mark A., Switzky, Julie, Ma, Bo, Goodman, Vicki L., Carson, Stanley W., Curtis, C. Martin, Streit, Michael R. W., Johnson, Bruce E.
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Pegathor Lymphoma, a Phase 2 Study of SAR444245 As a Monotherapy or in Combination with Pembrolizumab for the Treatment of Adults and Adolescents with Relapsed or Refractory B Cell Lymphoma
Berkovits, Alejandro, Yanez, Eduardo, Rojas, Christine, Gazitua, Raimundo, Cazap, Nicolás, Sureda, Anna, Saleem, Rao, Meng, Robin, Xu, Jing, Streit, Michael, Barboux, Valentine, Ahmed, Sairah
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Safety and activity of ibrutinib in combination with nivolumab in patients with relapsed non-Hodgkin lymphoma or chronic lymphocytic leukaemia: a phase 1/2a study
Younes, Anas, Brody, Joshua, Carpio, Cecilia, Lopez-Guillermo, Armando, Ben-Yehuda, Dina, Ferhanoglu, Burhan, Nagler, Arnon, Ozcan, Muhit, Avivi, Irit, Bosch, Francesc, Caballero Barrigón, Maria Dolores, Hellmann, Andrzej, Kuss, Bryone, Ma, David D F, Demirkan, Fatih, Yağci, Münci, Horowitz, Netanel A, Marlton, Paula, Cordoba, Raul, Wrobel, Tomasz, Buglio, Daniela, Streit, Michael, Hodkinson, Brendan P, Schaffer, Michael, Alvarez, John, Ceulemans, Rob, Balasubramanian, Sriram, de Jong, Jan, Wang, Shean-Sheng, Fourneau, Nele, Jurczak, Wojciech
Published in The Lancet. Haematology (01.02.2019)
Published in The Lancet. Haematology (01.02.2019)
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Cytochrome P450 enzyme-mediated drug metabolism at exposure to acute hypoxia (corresponding to an altitude of 4,500 m)
STREIT, Michael, GÖGGELMANN, Christoph, DEHNERT, Christoph, BURHENNE, Jürgen, RIEDEL, Klaus-Dieter, MENOLD, Elmar, MIKUS, Gerd, BÄRTSCH, Peter, HAEFELI, Walter E
Published in European journal of clinical pharmacology (01.03.2005)
Published in European journal of clinical pharmacology (01.03.2005)
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Abstract PO1-20-04: STX-478-101: A phase 1/2, first-in-human study of STX-478 monotherapy or in combination with fulvestrant in patients with breast cancer or other advanced solid tumors (trial in progress)
Montero, Alberto, Orr, Douglas, Munster, Pamela, LoRusso, Patricia, Jhaveri, Komal, Pluard, Timothy, Winer, Ira, Streit, Michael, Patterson, Monica, Roberts, Simon, Corsi-Travali, Stefani, Ewert, Courtney, Juric, Dejan
Published in Cancer research (Chicago, Ill.) (02.05.2024)
Published in Cancer research (Chicago, Ill.) (02.05.2024)
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Abstract 2319: Deep learning-enabled dynamic infiltration and response to NK therapies in solid tumor organoids
Lonini, Luca, Khare, Sonal, Lopez, Timothy Don, Szydlo, Stanislaw, Streit, Michael, Karginova, Olga A., Flaherty, Mary K., Salhaudeen, Ameen, Kunert, Andre, Oja, Anna, Sasser, Kate, Stumpe, Martin C., Ho, Chi-Sing
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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