The landscape of kinase fusions in cancer
Stransky, Nicolas, Cerami, Ethan, Schalm, Stefanie, Kim, Joseph L., Lengauer, Christoph
Published in Nature communications (10.09.2014)
Published in Nature communications (10.09.2014)
Get full text
Journal Article
Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer
Dutt, Amit, Ramos, Alex H, Hammerman, Peter S, Mermel, Craig, Cho, Jeonghee, Sharifnia, Tanaz, Chande, Ajit, Tanaka, Kumiko Elisa, Stransky, Nicolas, Greulich, Heidi, Gray, Nathanael S, Meyerson, Matthew
Published in PloS one (07.06.2011)
Published in PloS one (07.06.2011)
Get full text
Journal Article
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
Cheung, Hiu Wing, Cowley, Glenn S, Weir, Barbara A, Boehm, Jesse S, Rusin, Scott, Scott, Justine A, East, Alexandra, Ali, Levi D, Lizotte, Patrick H, Wong, Terence C, Jiang, Guozhi, Hsiao, Jessica, Mermel, Craig H, Getz, Gad, Barretina, Jordi, Gopal, Shuba, Tamayo, Pablo, Gould, Joshua, Tsherniak, Aviad, Stransky, Nicolas, Luo, Biao, Ren, Yin, Drapkin, Ronny, Bhatia, Sangeeta N, Mesirov, Jill P, Garraway, Levi A, Meyerson, Matthew, Lander, Eric S, Root, David E, Hahn, William C
Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2011)
Get full text
Journal Article
Nuclear factor I/B is an oncogene in small cell lung cancer
Dooley, Alison L, Winslow, Monte M, Chiang, Derek Y, Banerji, Shantanu, Stransky, Nicolas, Dayton, Talya L, Snyder, Eric L, Senna, Stephanie, Whittaker, Charles A, Bronson, Roderick T, Crowley, Denise, Barretina, Jordi, Garraway, Levi, Meyerson, Matthew, Jacks, Tyler
Published in Genes & development (15.07.2011)
Published in Genes & development (15.07.2011)
Get full text
Journal Article
Analysis of array CGH data: from signal ratio to gain and loss of DNA regions
Hupé, Philippe, Stransky, Nicolas, Thiery, Jean-Paul, Radvanyi, François, Barillot, Emmanuel
Published in Bioinformatics (12.12.2004)
Published in Bioinformatics (12.12.2004)
Get full text
Journal Article
ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens
Shao, Diane D, Tsherniak, Aviad, Gopal, Shuba, Weir, Barbara A, Tamayo, Pablo, Stransky, Nicolas, Schumacher, Steven E, Zack, Travis I, Beroukhim, Rameen, Garraway, Levi A, Margolin, Adam A, Root, David E, Hahn, William C, Mesirov, Jill P
Published in Genome research (01.04.2013)
Published in Genome research (01.04.2013)
Get full text
Journal Article
TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer
Dufour, Florent, Silina, Linda, Neyret-Kahn, Hélène, Moreno-Vega, Aura, Krucker, Clémentine, Karboul, Narjesse, Dorland-Galliot, Marion, Maillé, Pascale, Chapeaublanc, Elodie, Allory, Yves, Stransky, Nicolas, Haegel, Hélène, Menguy, Thierry, Duong, Vanessa, Radvanyi, François, Bernard-Pierrot, Isabelle
Published in British journal of cancer (05.03.2019)
Published in British journal of cancer (05.03.2019)
Get full text
Journal Article
Frequent genomic structural alterations at HPV insertion sites in cervical carcinoma
Peter, Martine, Stransky, Nicolas, Couturier, Jérôme, Hupé, Philippe, Barillot, Emmanuel, de Cremoux, Patricia, Cottu, Paul, Radvanyi, Francois, Sastre-Garau, Xavier
Published in The Journal of pathology (01.07.2010)
Published in The Journal of pathology (01.07.2010)
Get full text
Journal Article
Characterization of the recurrent 8p11-12 amplicon identifies PPAPDC1B, a phosphatase protein, as a new therapeutic target in breast cancer
Bernard-Pierrot, Isabelle, Gruel, Nadège, Stransky, Nicolas, Vincent-Salomon, Anne, Reyal, Fabien, Raynal, Virginie, Vallot, Céline, Pierron, Gaëlle, Radvanyi, François, Delattre, Olivier
Published in Cancer research (Chicago, Ill.) (01.09.2008)
Published in Cancer research (Chicago, Ill.) (01.09.2008)
Get full text
Journal Article
Evaluation of Protein Kinase cAMP-Activated Catalytic Subunit Alpha as a Therapeutic Target for Fibrolamellar Carcinoma
Schalm, Stefanie S., O’Hearn, Erin, Wilson, Kevin, LaBranche, Timothy P., Silva, Grace, Zhang, Zhuo, DiPietro, Lucian, Bifulco, Neil, Woessner, Richard, Stransky, Nicolas, Sappal, Darshan, Campbell, Robert, Lobbardi, Riadh, Palmer, Michael, Kim, Joseph, Ye, Chaoyang, Dorsch, Marion, Lengauer, Christoph, Guzi, Timothy, Kadambi, Vivek, Garner, Andrew, Hoeflich, Klaus P.
Published in Gastro hep advances (2023)
Published in Gastro hep advances (2023)
Get full text
Journal Article
Targeting cancer with kinase inhibitors
Gross, Stefan, Rahal, Rami, Stransky, Nicolas, Lengauer, Christoph, Hoeflich, Klaus P
Published in The Journal of clinical investigation (01.05.2015)
Published in The Journal of clinical investigation (01.05.2015)
Get full text
Journal Article
Next-generation characterization of the Cancer Cell Line Encyclopedia
Ghandi, Mahmoud, Huang, Franklin W., Jané-Valbuena, Judit, Kryukov, Gregory V., Lo, Christopher C., McDonald, E. Robert, Barretina, Jordi, Gelfand, Ellen T., Bielski, Craig M., Li, Haoxin, Hu, Kevin, Andreev-Drakhlin, Alexander Y., Kim, Jaegil, Hess, Julian M., Haas, Brian J., Aguet, François, Weir, Barbara A., Rothberg, Michael V., Paolella, Brenton R., Lawrence, Michael S., Akbani, Rehan, Lu, Yiling, Tiv, Hong L., Gokhale, Prafulla C., de Weck, Antoine, Mansour, Ali Amin, Oh, Coyin, Shih, Juliann, Hadi, Kevin, Rosen, Yanay, Bistline, Jonathan, Venkatesan, Kavitha, Reddy, Anupama, Sonkin, Dmitriy, Liu, Manway, Lehar, Joseph, Korn, Joshua M., Porter, Dale A., Jones, Michael D., Golji, Javad, Caponigro, Giordano, Taylor, Jordan E., Dunning, Caitlin M., Creech, Amanda L., Warren, Allison C., McFarland, James M., Zamanighomi, Mahdi, Kauffmann, Audrey, Stransky, Nicolas, Imielinski, Marcin, Maruvka, Yosef E., Cherniack, Andrew D., Tsherniak, Aviad, Vazquez, Francisca, Jaffe, Jacob D., Lane, Andrew A., Weinstock, David M., Johannessen, Cory M., Morrissey, Michael P., Stegmeier, Frank, Schlegel, Robert, Hahn, William C., Getz, Gad, Mills, Gordon B., Boehm, Jesse S., Golub, Todd R., Garraway, Levi A., Sellers, William R.
Published in Nature (London) (01.05.2019)
Published in Nature (London) (01.05.2019)
Get full text
Journal Article
First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway
Hagel, Margit, Miduturu, Chandra, Sheets, Michael, Rubin, Nooreen, Weng, Weifan, Stransky, Nicolas, Bifulco, Neil, Kim, Joseph L, Hodous, Brian, Brooijmans, Natasja, Shutes, Adam, Winter, Christopher, Lengauer, Christoph, Kohl, Nancy E, Guzi, Timothy
Published in Cancer discovery (01.04.2015)
Published in Cancer discovery (01.04.2015)
Get full text
Journal Article
Pharmacogenomic agreement between two cancer cell line data sets
Stransky, Nicolas, Ghandi, Mahmoud, Kryukov, Gregory V, Garraway, Levi A, Lehár, Joseph, Liu, Manway, Sonkin, Dmitriy, Kauffmann, Audrey, Venkatesan, Kavitha, Edelman, Elena J, Riester, Markus, Barretina, Jordi, Caponigro, Giordano, Schlegel, Robert, Sellers, William R, Stegmeier, Frank, Morrissey, Michael, Amzallag, Arnaud, Pruteanu-Malinici, Iulian, Haber, Daniel A, Ramaswamy, Sridhar, Benes, Cyril H, Menden, Michael P, Iorio, Francesco, Stratton, Michael R, McDermott, Ultan, Garnett, Mathew J, Saez-Rodriguez, Julio
Published in Nature (London) (03.12.2015)
Published in Nature (London) (03.12.2015)
Get full text
Journal Article
Mutational heterogeneity in cancer and the search for new cancer-associated genes
Lawrence, Michael S., Stojanov, Petar, Polak, Paz, Kryukov, Gregory V., Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L., Stewart, Chip, Mermel, Craig H., Roberts, Steven A., Kiezun, Adam, Hammerman, Peter S., McKenna, Aaron, Drier, Yotam, Zou, Lihua, Ramos, Alex H., Pugh, Trevor J., Stransky, Nicolas, Helman, Elena, Kim, Jaegil, Sougnez, Carrie, Ambrogio, Lauren, Nickerson, Elizabeth, Shefler, Erica, Cortés, Maria L., Auclair, Daniel, Saksena, Gordon, Voet, Douglas, Noble, Michael, DiCara, Daniel, Lin, Pei, Lichtenstein, Lee, Heiman, David I., Fennell, Timothy, Imielinski, Marcin, Hernandez, Bryan, Hodis, Eran, Baca, Sylvan, Dulak, Austin M., Lohr, Jens, Landau, Dan-Avi, Wu, Catherine J., Melendez-Zajgla, Jorge, Hidalgo-Miranda, Alfredo, Koren, Amnon, McCarroll, Steven A., Mora, Jaume, Lee, Ryan S., Crompton, Brian, Onofrio, Robert, Parkin, Melissa, Winckler, Wendy, Ardlie, Kristin, Gabriel, Stacey B., Roberts, Charles W. M., Biegel, Jaclyn A., Stegmaier, Kimberly, Bass, Adam J., Garraway, Levi A., Meyerson, Matthew, Golub, Todd R., Gordenin, Dmitry A., Sunyaev, Shamil, Lander, Eric S., Getz, Gad
Published in Nature (London) (11.07.2013)
Published in Nature (London) (11.07.2013)
Get full text
Journal Article
The Mutational Landscape of Head and Neck Squamous Cell Carcinoma
Stransky, Nicolas, Egloff, Ann Marie, Tward, Aaron D., Kostic, Aleksandar D., Cibulskis, Kristian, Sivachenko, Andrey, Kryukov, Gregory V., Lawrence, Michael S., Sougnez, Carrie, McKenna, Aaron, Shefler, Erica, Ramos, Alex H., Stojanov, Petar, Carter, Scott L., Voet, Douglas, Cortés, Maria L., Auclair, Daniel, Berger, Michael F., Saksena, Gordon, Guiducci, Candace, Onofrio, Robert C., Parkin, Melissa, Romkes, Marjorie, Weissfeld, Joel L., Seethala, Raja R., Wang, Lin, Rangel-Escareño, Claudia, Fernandez-Lopez, Juan Carlos, Hidalgo-Miranda, Alfredo, Melendez-Zajgla, Jorge, Winckler, Wendy, Ardlie, Kristin, Gabriel, Stacey B., Meyerson, Matthew, Lander, Eric S., Getz, Gad, Golub, Todd R., Garraway, Levi A., Grandis, Jennifer R.
Published in Science (American Association for the Advancement of Science) (26.08.2011)
Published in Science (American Association for the Advancement of Science) (26.08.2011)
Get full text
Journal Article
Sequence analysis of mutations and translocations across breast cancer subtypes
Banerji, Shantanu, Cibulskis, Kristian, Rangel-Escareno, Claudia, Brown, Kristin K., Carter, Scott L., Frederick, Abbie M., Lawrence, Michael S., Sivachenko, Andrey Y., Sougnez, Carrie, Zou, Lihua, Cortes, Maria L., Fernandez-Lopez, Juan C., Peng, Shouyong, Ardlie, Kristin G., Auclair, Daniel, Bautista-Piña, Veronica, Duke, Fujiko, Francis, Joshua, Jung, Joonil, Maffuz-Aziz, Antonio, Onofrio, Robert C., Parkin, Melissa, Pho, Nam H., Quintanar-Jurado, Valeria, Ramos, Alex H., Rebollar-Vega, Rosa, Rodriguez-Cuevas, Sergio, Romero-Cordoba, Sandra L., Schumacher, Steven E., Stransky, Nicolas, Thompson, Kristin M., Uribe-Figueroa, Laura, Baselga, Jose, Beroukhim, Rameen, Polyak, Kornelia, Sgroi, Dennis C., Richardson, Andrea L., Jimenez-Sanchez, Gerardo, Lander, Eric S., Gabriel, Stacey B., Garraway, Levi A., Golub, Todd R., Melendez-Zajgla, Jorge, Toker, Alex, Getz, Gad, Hidalgo-Miranda, Alfredo, Meyerson, Matthew
Published in Nature (London) (21.06.2012)
Published in Nature (London) (21.06.2012)
Get full text
Journal Article
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
Possemato, Richard, Marks, Kevin M., Shaul, Yoav D., Pacold, Michael E., Kim, Dohoon, Birsoy, Kıvanç, Sethumadhavan, Shalini, Woo, Hin-Koon, Jang, Hyun G., Jha, Abhishek K., Chen, Walter W., Barrett, Francesca G., Stransky, Nicolas, Tsun, Zhi-Yang, Cowley, Glenn S., Barretina, Jordi, Kalaany, Nada Y., Hsu, Peggy P., Ottina, Kathleen, Chan, Albert M., Yuan, Bingbing, Garraway, Levi A., Root, David E., Mino-Kenudson, Mari, Brachtel, Elena F., Driggers, Edward M., Sabatini, David M.
Published in Nature (London) (18.08.2011)
Published in Nature (London) (18.08.2011)
Get full text
Journal Article
A Landscape of Driver Mutations in Melanoma
Hodis, Eran, Watson, Ian R., Kryukov, Gregory V., Arold, Stefan T., Imielinski, Marcin, Theurillat, Jean-Philippe, Nickerson, Elizabeth, Auclair, Daniel, Li, Liren, Place, Chelsea, DiCara, Daniel, Ramos, Alex H., Lawrence, Michael S., Cibulskis, Kristian, Sivachenko, Andrey, Voet, Douglas, Saksena, Gordon, Stransky, Nicolas, Onofrio, Robert C., Winckler, Wendy, Ardlie, Kristin, Wagle, Nikhil, Wargo, Jennifer, Chong, Kelly, Morton, Donald L., Stemke-Hale, Katherine, Chen, Guo, Noble, Michael, Meyerson, Matthew, Ladbury, John E., Davies, Michael A., Gershenwald, Jeffrey E., Wagner, Stephan N., Hoon, Dave S.B., Schadendorf, Dirk, Lander, Eric S., Gabriel, Stacey B., Getz, Gad, Garraway, Levi A., Chin, Lynda
Published in Cell (20.07.2012)
Published in Cell (20.07.2012)
Get full text
Journal Article