Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin
Laursen, Nick S, Friesen, Robert H E, Zhu, Xueyong, Jongeneelen, Mandy, Blokland, Sven, Vermond, Jan, van Eijgen, Alida, Tang, Chan, van Diepen, Harry, Obmolova, Galina, van der Neut Kolfschoten, Marijn, Zuijdgeest, David, Straetemans, Roel, Hoffman, Ryan M B, Nieusma, Travis, Pallesen, Jesper, Turner, Hannah L, Bernard, Steffen M, Ward, Andrew B, Luo, Jinquan, Poon, Leo L M, Tretiakova, Anna P, Wilson, James M, Limberis, Maria P, Vogels, Ronald, Brandenburg, Boerries, Kolkman, Joost A, Wilson, Ian A
Published in Science (American Association for the Advancement of Science) (02.11.2018)
Published in Science (American Association for the Advancement of Science) (02.11.2018)
Get full text
Journal Article
SARS-CoV-2 binding and neutralizing antibody levels after Ad26.COV2.S vaccination predict durable protection in rhesus macaques
Roozendaal, Ramon, Solforosi, Laura, Stieh, Daniel J., Serroyen, Jan, Straetemans, Roel, Dari, Anna, Boulton, Muriel, Wegmann, Frank, Rosendahl Huber, Sietske K., van der Lubbe, Joan E. M., Hendriks, Jenny, Le Gars, Mathieu, Dekking, Liesbeth, Czapska-Casey, Dominika N., Guimera, Nuria, Janssen, Sarah, Tete, Sarah, Chandrashekar, Abishek, Mercado, Noe B., Yu, Jingyou, Koudstaal, Wouter, Perez-Ruixo, Juan J., Sadoff, Jerry, Barouch, Dan H., Schuitemaker, Hanneke, Zahn, Roland
Published in Nature communications (07.10.2021)
Published in Nature communications (07.10.2021)
Get full text
Journal Article
Memantine-induced brain activation as a model for the rapid screening of potential novel antipsychotic compounds: exemplified by activity of an mGlu2/3 receptor agonist
Dedeurwaerdere, Stefanie, Wintmolders, Cindy, Straetemans, Roel, Pemberton, Darrel, Langlois, Xavier
Published in Psychopharmacologia (01.03.2011)
Published in Psychopharmacologia (01.03.2011)
Get full text
Journal Article
Lack of lithium-like behavioral and molecular effects in IMPA2 knockout mice
CRYNS, Kim, SHAMIR, Alon, STECKLER, Thomas, SHAPIRO, Joseph, DANEELS, Gie, GORIS, Ilse, VAN CRAENENDONCK, Hansfried, STRAETEMANS, Roel, BELMAKER, Rh, AGAM, Galila, MOECHARS, Dieder
Published in Neuropsychopharmacology (New York, N.Y.) (01.04.2007)
Published in Neuropsychopharmacology (New York, N.Y.) (01.04.2007)
Get full text
Journal Article
Prediction of Human Oral Plasma Concentration-Time Profiles Using Preclinical Data
Van den Bergh, An, Sinha, Vikash, Gilissen, Ron, Straetemans, Roel, Wuyts, Koen, Morrison, Denise, Bijnens, Luc, Mackie, Claire
Published in Clinical pharmacokinetics (01.08.2011)
Published in Clinical pharmacokinetics (01.08.2011)
Get full text
Journal Article
Blocking NS3–NS4B interaction inhibits dengue virus in non-human primates
Goethals, Olivia, Kaptein, Suzanne J. F., Kesteleyn, Bart, Bonfanti, Jean-François, Van Wesenbeeck, Liesbeth, Bardiot, Dorothée, Verschoor, Ernst J., Verstrepen, Babs E., Fagrouch, Zahra, Putnak, J. Robert, Kiemel, Dominik, Ackaert, Oliver, Straetemans, Roel, Lachau-Durand, Sophie, Geluykens, Peggy, Crabbe, Marjolein, Thys, Kim, Stoops, Bart, Lenz, Oliver, Tambuyzer, Lotke, De Meyer, Sandra, Dallmeier, Kai, McCracken, Michael K., Gromowski, Gregory D., Rutvisuttinunt, Wiriya, Jarman, Richard G., Karasavvas, Nicos, Touret, Franck, Querat, Gilles, de Lamballerie, Xavier, Chatel-Chaix, Laurent, Milligan, Gregg N., Beasley, David W. C., Bourne, Nigel, Barrett, Alan D. T., Marchand, Arnaud, Jonckers, Tim H. M., Raboisson, Pierre, Simmen, Kenny, Chaltin, Patrick, Bartenschlager, Ralf, Bogers, Willy M., Neyts, Johan, Van Loock, Marnix
Published in Nature (London) (23.03.2023)
Published in Nature (London) (23.03.2023)
Get full text
Journal Article
Prediction of Human Oral Plasma Concentration-Time Profiles Using Preclinical Data: Comparative Evaluation of Prediction Approaches in Early Pharmaceutical Discovery
Van den Bergh, An, Sinha, Vikash, Gilissen, Ron, Straetemans, Roel, Wuyts, Koen, Morrison, Denise, Bijnens, Luc, Mackie, Claire
Published in Clinical pharmacokinetics (01.08.2011)
Published in Clinical pharmacokinetics (01.08.2011)
Get full text
Journal Article
Universal Protection against Influenza Infection by a Multi-Domain Antibody to Influenza Hemagglutinin
Laursen, Nick S., Friesen, Robert H. E., Zhu, Xueyong, Jongeneelen, Mandy, Blokland, Sven, Vermond, Jan, van Eijgen, Alida, Tang, Chan, van Diepen, Harry, Oblomova, Galina, van der Neut Kolfschoten, Marijn, Zuijdgeest, David, Straetemans, Roel, Hoffman, Ryan M. B., Nieusma, Travis, Pallesen, Jesper, Turner, Hannah L., Bernard, Steffen M., Ward, Andrew B., Luo, Jinquan, Poon, Leo L. M., Tretiakova, Anna P., Wilson, James M., Limberis, Maria P., Vogels, Ronald, Brandenburg, Boerries, Kolkman, Joost A., Wilson, Ian A.
Published in Science (American Association for the Advancement of Science) (02.11.2018)
Published in Science (American Association for the Advancement of Science) (02.11.2018)
Get full text
Journal Article
A canine model to evaluate efficacy and safety of γ-secretase inhibitors and modulators
Borghys, Herman, Tuefferd, Marianne, Van Broeck, Bianca, Clessens, Ellen, Dillen, Lieve, Cools, Willy, Vinken, Petra, Straetemans, Roel, De Ridder, Filip, Gijsen, Harrie, Mercken, Marc
Published in Journal of Alzheimer's disease (01.01.2012)
Published in Journal of Alzheimer's disease (01.01.2012)
Get more information
Journal Article
Differences in nociceptive behavioral performance between C57BL/6J, 129S6/SvEv, B6 129 F1 and NMRI mice
Leo, Sandra, Straetemans, Roel, D’Hooge, Rudi, Meert, Theo
Published in Behavioural brain research (19.07.2008)
Published in Behavioural brain research (19.07.2008)
Get full text
Journal Article
The fentanyl/etomidate-anaesthetised beagle (FEAB) dog: A versatile in vivo model in Cardiovascular Safety Research
Van Deuren, Bruno, Van Ammel, Karel, Somers, Yves, Cools, Frank, Straetemans, Roel, van der Linde, Henk J., Gallacher, David J.
Published in Journal of pharmacological and toxicological methods (01.07.2009)
Published in Journal of pharmacological and toxicological methods (01.07.2009)
Get full text
Journal Article
Can retrospective analysis of preclinical cardiovascular safety data improve predictivity of future results?
Guns, Pieter-Jan, Teisman, Ard, Van Ammel, Karel, Towart, Rob, Straetemans, Roel, Bult, Hidde, Gallacher, David
Published in Journal of pharmacological and toxicological methods (01.09.2010)
Published in Journal of pharmacological and toxicological methods (01.09.2010)
Get full text
Journal Article
Pharmacokinetics and pharmacodynamics following γ-secretase modulator and inhibitor treatment of Cynomolgus monkeys (Macaca fascicularis)
Van Broeck, Bianca, Mercken, Marc, de Villa, Flordeliza, Hutcheson, Daniel, Karran, Eric, Barao, Ana, Hermans, Bart, Straetemans, Roel, De Ridder, Filip
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
Get full text
Journal Article
P1‐121: Pharmacokinetics and pharmacodynamics following γ‐secretase modulator and inhibitor treatment of Cynomolgus monkeys (Macaca fascicularis)
Van Broeck, Bianca, Mercken, Marc, Villa, Flordeliza, Hutcheson, Daniel, Karran, Eric, Barao, Ana, Hermans, Bart, Straetemans, Roel, De Ridder, Filip
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
Get full text
Journal Article
Design and Analysis of Drug Combination Experiments
Straetemans, Roel, O'Brien, Timothy, Wouters, Luc, Van Dun, Jacky, Janicot, Michel, Bijnens, Luc, Burzykowski, Tomasz, Aerts, Marc
Published in Biometrical journal (01.06.2005)
Published in Biometrical journal (01.06.2005)
Get full text
Journal Article