Optimization of a Series of Bivalent Triazolopyridazine Based Bromodomain and Extraterminal Inhibitors: The Discovery of (3R)‑4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3‑b]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one (AZD5153)
Bradbury, Robert H, Callis, Rowena, Carr, Gregory R, Chen, Huawei, Clark, Edwin, Feron, Lyman, Glossop, Steve, Graham, Mark A, Hattersley, Maureen, Jones, Chris, Lamont, Scott G, Ouvry, Gilles, Patel, Anil, Patel, Joe, Rabow, Alfred A, Roberts, Craig A, Stokes, Stephen, Stratton, Natalie, Walker, Graeme E, Ward, Lara, Whalley, David, Whittaker, David, Wrigley, Gail, Waring, Michael J
Published in Journal of medicinal chemistry (08.09.2016)
Published in Journal of medicinal chemistry (08.09.2016)
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Journal Article
Insight into the Mechanism of Formation of Channel Hydrates via Templating
Stokes, Stephen P, Seaton, Colin C, Eccles, Kevin S, Maguire, Anita R, Lawrence, Simon E
Published in Crystal growth & design (05.03.2014)
Published in Crystal growth & design (05.03.2014)
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A Combined Total Scattering and Simulation Approach to Analyzing Defect Structure in Bi3YO6
Abrahams, Isaac, Liu, Xi, Hull, Stephen, Norberg, Stefan T, Krok, Franciszek, Kozanecka-Szmigiel, Anna, Islam, M. Saiful, Stokes, Stephen J
Published in Chemistry of materials (10.08.2010)
Published in Chemistry of materials (10.08.2010)
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Changes in natural OSL sensitivity during single aliquot regeneration procedure and their implications for equivalent dose determination
Singhvi, Ashok K., Stokes, Stephen C., Chauhan, Naveen, Nagar, Yogesh C., Jaiswal, Manoj K.
Published in Geochronometria (01.09.2011)
Published in Geochronometria (01.09.2011)
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Holocene slip-rate on the Sabzevar thrust fault, NE Iran, determined using optically stimulated luminescence (OSL)
Fattahi, Morteza, Walker, Richard, Hollingsworth, James, Bahroudi, Abbas, Nazari, Hamid, Talebian, Morteza, Armitage, Simon, Stokes, Stephen
Published in Earth and planetary science letters (30.05.2006)
Published in Earth and planetary science letters (30.05.2006)
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Journal Article
Sulfoxides: Potent Co-Crystal Formers
Eccles, Kevin S, Elcoate, Curtis J, Stokes, Stephen P, Maguire, Anita R, Lawrence, Simon E
Published in Crystal growth & design (06.10.2010)
Published in Crystal growth & design (06.10.2010)
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Journal Article
Conference Proceeding
Utilizing Sulfoxide···Iodine Halogen Bonding for Cocrystallization
Eccles, Kevin S, Morrison, Robin E, Stokes, Stephen P, O’Mahony, Graham E, Hayes, John A, Kelly, Dawn M, O’Boyle, Noel M, Fábián, László, Moynihan, Humphrey A, Maguire, Anita R, Lawrence, Simon E
Published in Crystal growth & design (06.06.2012)
Published in Crystal growth & design (06.06.2012)
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Journal Article
Evaluation of the Bruker SMART X2S: crystallography for the nonspecialist?
Eccles, Kevin S., Stokes, Stephen P., Daly, Carla A., Barry, Nicola M., McSweeney, Sharon P., O'Neill, Damian J., Kelly, Dawn M., Jennings, W. Brian, Ní Dhubhghaill, O. M., Moynihan, Humphrey A., Maguire, Anita R., Lawrence, Simon E.
Published in Journal of applied crystallography (01.02.2011)
Published in Journal of applied crystallography (01.02.2011)
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Towards the enantioselective synthesis of (-)-euonyminol - preparation of a fully functionalised lower-rim model
Webber, Matthew J., Warren, Sarah A., Grainger, Damian M., Weston, Matthew, Clark, Stacy, Woodhead, Steven J., Powell, Lyn, Stokes, Stephen, Alanine, Alexander, Stonehouse, Jeffrey P., Frampton, Christopher S., White, Andrew J. P., Spivey, Alan C.
Published in Organic & biomolecular chemistry (21.04.2013)
Published in Organic & biomolecular chemistry (21.04.2013)
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Journal Article
Red emission luminescence from quartz and feldspar for dating applications: an overview
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Journal Article
Conference Proceeding
Will they co-crystallize?
Wicker, Jerome G. P., Crowley, Lorraine M., Robshaw, Oliver, Little, Edmund J., Stokes, Stephen P., Cooper, Richard I., Lawrence, Simon E.
Published in CrystEngComm (2017)
Published in CrystEngComm (2017)
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Journal Article
Synthesis of Ynone Trifluoroborates toward Functionalized Pyrazoles
Kirkham, James D, Edeson, Steven J, Stokes, Stephen, Harrity, Joseph P. A
Published in Organic letters (19.10.2012)
Published in Organic letters (19.10.2012)
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Journal Article
Optimization of a Series of Bivalent Triazolopyridazine Based Bromodomain and Extraterminal Inhibitors: The Discovery of (3R)-4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-piperidyl]phenoxylethy]-1,3-dimethyl-piperazin-2-one (AZD5153)
Bradbury, Robert H., Callis, Rowena, Carr, Gregory R., Chen, Huawei, Clark, Edwin, Feron, Lyman, Glossop, Steve, Graham, Mark A., Hattersley, Maureen, Jones, Chris, Lamont, Scott G., Ouvry, Gilles, Patel, Anil, Patel, Joe, Rabow, Alfred A., Roberts, Craig A., Stokes, Stephen, Stratton, Natalie, Walker, Graeme E., Ward, Lara, Whalley, David, Whittaker, David, Wrigley, Gail, Waring, Michael J.
Published in Journal of medicinal chemistry (08.09.2016)
Published in Journal of medicinal chemistry (08.09.2016)
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Journal Article
Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist
Scott, James S, Moss, Thomas A, Balazs, Amber, Barlaam, Bernard, Breed, Jason, Carbajo, Rodrigo J, Chiarparin, Elisabetta, Davey, Paul R. J, Delpuech, Oona, Fawell, Stephen, Fisher, David I, Gagrica, Sladjana, Gangl, Eric T, Grebe, Tyler, Greenwood, Ryan D, Hande, Sudhir, Hatoum-Mokdad, Holia, Herlihy, Kara, Hughes, Samantha, Hunt, Thomas A, Huynh, Hoan, Janbon, Sophie L. M, Johnson, Tony, Kavanagh, Stefan, Klinowska, Teresa, Lawson, Mandy, Lister, Andrew S, Marden, Stacey, McGinnity, Dermot F, Morrow, Christopher J, Nissink, J. Willem M, O’Donovan, Daniel H, Peng, Bo, Polanski, Radoslaw, Stead, Darren S, Stokes, Stephen, Thakur, Kumar, Throner, Scott R, Tucker, Michael J, Varnes, Jeffrey, Wang, Haixia, Wilson, David M, Wu, Dedong, Wu, Ye, Yang, Bin, Yang, Wenzhan
Published in Journal of medicinal chemistry (10.12.2020)
Published in Journal of medicinal chemistry (10.12.2020)
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