EMD 1214063 and EMD 1204831 Constitute a New Class of Potent and Highly Selective c-Met Inhibitors
BLADT, Friedhelm, FADEN, Bettina, PEHL, Ulrich, STIEBER, Frank, SCHADT, Oliver, BLAUKAT, Andree, FRIESE-HAMIM, Manja, KNUEHL, Christine, WILM, Claudia, FITTSCHEN, Claus, GRÄDLER, Ulrich, MEYRING, Michael, DORSCH, Dieter, JAEHRLING, Frank
Published in Clinical cancer research (01.06.2013)
Published in Clinical cancer research (01.06.2013)
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Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19
Mallinger, Aurélie, Schiemann, Kai, Rink, Christian, Stieber, Frank, Calderini, Michel, Crumpler, Simon, Stubbs, Mark, Adeniji-Popoola, Olajumoke, Poeschke, Oliver, Busch, Michael, Czodrowski, Paul, Musil, Djordje, Schwarz, Daniel, Ortiz-Ruiz, Maria-Jesus, Schneider, Richard, Thai, Ching, Valenti, Melanie, de Haven Brandon, Alexis, Burke, Rosemary, Workman, Paul, Dale, Trevor, Wienke, Dirk, Clarke, Paul A, Esdar, Christina, Raynaud, Florence I, Eccles, Suzanne A, Rohdich, Felix, Blagg, Julian
Published in Journal of medicinal chemistry (11.02.2016)
Published in Journal of medicinal chemistry (11.02.2016)
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Discovery of Potent, Orally Bioavailable, Small-Molecule Inhibitors of WNT Signaling from a Cell-Based Pathway Screen
Mallinger, Aurélie, Crumpler, Simon, Pichowicz, Mark, Waalboer, Dennis, Stubbs, Mark, Adeniji-Popoola, Olajumoke, Wood, Bozena, Smith, Elizabeth, Thai, Ching, Henley, Alan T, Georgi, Katrin, Court, William, Hobbs, Steve, Box, Gary, Ortiz-Ruiz, Maria-Jesus, Valenti, Melanie, De Haven Brandon, Alexis, TePoele, Robert, Leuthner, Birgitta, Workman, Paul, Aherne, Wynne, Poeschke, Oliver, Dale, Trevor, Wienke, Dirk, Esdar, Christina, Rohdich, Felix, Raynaud, Florence, Clarke, Paul A, Eccles, Suzanne A, Stieber, Frank, Schiemann, Kai, Blagg, Julian
Published in Journal of medicinal chemistry (26.02.2015)
Published in Journal of medicinal chemistry (26.02.2015)
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An Oxidation-Labile Traceless Linker for Solid-Phase Synthesis
Stieber, Frank, Grether, Uwe, Waldmann, Herbert
Published in Angewandte Chemie (International ed.) (19.04.1999)
Published in Angewandte Chemie (International ed.) (19.04.1999)
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Multistep Solid-Phase Synthesis of an Antibiotic and Receptor Tyrosine Kinase Inhibitors Using the Traceless Phenylhydrazide Linker
Stieber, Frank, Grether, Uwe, Mazitschek, Ralph, Soric, Natascha, Giannis, Athanassios, Waldmann, Herbert
Published in Chemistry : a European journal (21.07.2003)
Published in Chemistry : a European journal (21.07.2003)
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Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors
Dorsch, Dieter, Schadt, Oliver, Stieber, Frank, Meyring, Michael, Grädler, Ulrich, Bladt, Friedhelm, Friese-Hamim, Manja, Knühl, Christine, Pehl, Ulrich, Blaukat, Andree
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
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COMPOUNDS AND ORGANIC ELECTRONIC DEVICES
STIEBER FRANK, VOGES FRANK, MUJICA FERNAUD TERESA, PFISTER JOCHEN, MONTENEGRO ELVIRA
Year of Publication 12.01.2024
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Year of Publication 12.01.2024
Patent
MATERIALS FOR ELECTRONIC DEVICES
KAISER JOACHIM, STIEBER FRANK, STOESSEL PHILIPP, VOGES FRANK, MUJICA FERNAUD TERESA, PFLUMM CHRISTOF
Year of Publication 26.11.2019
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Year of Publication 26.11.2019
Patent
Abstract 1787: The c-Met inhibitors EMD 1214063 and EMD 1204831 are effective in combination with EGFR and VEGF inhibitors in NSCLC models
Bladt, Friedhelm, Blaukat, Andree, Dorsch, Dieter, Friese-Hamim, Manja, Meyring, Michael, Schadt, Oliver, Stieber, Frank
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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MATERIALS FOR ELECTRONIC DEVICES
STIEBER FRANK, MUJICA FERNAUD TERESA, PFISTER JOCHEN, MONTENEGRO ELVIRA
Year of Publication 25.08.2017
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Year of Publication 25.08.2017
Patent
Abstract 3025: Discovery of preclinical development candidate inhibitors of the mediator complex-associated kinases CDK8 and CDK19 and evaluation of their therapeutic potential
Clarke, Paul, Esdar, Christina, Mallinger, Aurelie, Schiemann, Kai, Waalboer, Dennis, Crumpler, Simon, Rink, Christian, Stieber, Frank, Calderini, Michel, Adeniji-Popoola, Olajumoke, Ortiz-Ruiz, Maria-Jesus, Samant, Rahul S., Czodrowski, Paul, Musil, Djordje, Schwarz, Daniel, Schneider, Klaus, Busch, Michael, Stubbs, Mark, Burke, Rosemary, TePoele, Robert, Gowan, Sharon, Rohdich, Felix, Raynaud, Florence, Schneider, Richard, Poeschke, Oliver, Blaukat, Andree, Urbahns, Klaus, Workman, Paul, Kaufmann, Wolfgang, Simon, Stephanie, Eccles, Suzanne A., Dale, Trevor, Wienke, Dirk, Blagg, Julian
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Design and synthesis of isoquinolines and benzimidazoles as RAF kinase inhibitors
Buchstaller, Hans-Peter, Burgdorf, Lars, Finsinger, Dirk, Stieber, Frank, Sirrenberg, Christian, Amendt, Christiane, Grell, Matthias, Zenke, Frank, Krier, Mireille
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
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유기 전계발광 소자용 재료
STIEBER FRANK, VOGES FRANK, MUJICA FERNAUD TERESA, PFISTER JOCHEN, MONTENEGRO ELVIRA
Year of Publication 28.03.2018
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Year of Publication 28.03.2018
Patent
COMPOUNDS AND ORGANIC ELECTRONIC DEVICES
STIEBER FRANK, VOGES FRANK, MUJICA FERNAUD TERESA, PFISTER JOCHEN, MONTENEGRO ELVIRA
Year of Publication 30.08.2017
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Year of Publication 30.08.2017
Patent
MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES
STIEBER FRANK, MUJICA FERNAUD TERESA, MONTENEGRO ELVIRA, PFISTER JOCHEN, MARTYNOVA IRINA
Year of Publication 09.08.2017
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Year of Publication 09.08.2017
Patent
MATERIALS FOR ELECTRONIC DEVICES
KAISER JOACHIM, STIEBER FRANK, STOESSEL PHILIPP, VOGES FRANK, MUJICA FERNAUD TERESA, PFLUMM CHRISTOF
Year of Publication 05.07.2017
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Year of Publication 05.07.2017
Patent
Abstract 2786: Identification and preclinical characterization of EMD 1204831 – A selective c-Met kinase inhibitor in clinical phase 1
Bladt, Friedhelm, Blaukat, Andree, Dorsch, Dieter, Fittschen, Claus, Friese-Hamim, Manja, Graedler, Ulrich, Knuehl, Christine, Meyring, Michael, Schadt, Oliver, Stieber, Frank
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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