Polyamine metabolism and cancer: treatments, challenges and opportunities
Casero, Robert A., Murray Stewart, Tracy, Pegg, Anthony E.
Published in Nature reviews. Cancer (01.11.2018)
Published in Nature reviews. Cancer (01.11.2018)
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Journal Article
Targeting polyamine metabolism for cancer therapy and prevention
Murray-Stewart, Tracy R, Woster, Patrick M, Casero, Jr, Robert A
Published in Biochemical journal (01.10.2016)
Published in Biochemical journal (01.10.2016)
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Journal Article
Expanded Potential of the Polyamine Analogue SBP-101 (Diethyl Dihydroxyhomospermine) as a Modulator of Polyamine Metabolism and Cancer Therapeutic
Holbert, Cassandra E., Foley, Jackson R., Murray Stewart, Tracy, Casero, Robert A.
Published in International journal of molecular sciences (18.06.2022)
Published in International journal of molecular sciences (18.06.2022)
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Journal Article
A phase I dose-escalation study of the polyamine analog PG-11047 in patients with advanced solid tumors
Murray Stewart, Tracy, Desai, Apurva A., Fitzgerald, Michael L., Marton, Laurence J., Casero, Robert A.
Published in Cancer chemotherapy and pharmacology (01.06.2020)
Published in Cancer chemotherapy and pharmacology (01.06.2020)
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Journal Article
Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis
Goodwin, Andrew C, Shields, Christina E. Destefano, Wu, Shaoguang, Huso, David L, Wu, XinQun, Murray-Stewart, Tracy R, Hacker-Prietz, Amy, Rabizadeh, Shervin, Woster, Patrick M, Sears, Cynthia L, Casero, Robert A. Jr
Published in Proceedings of the National Academy of Sciences - PNAS (13.09.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (13.09.2011)
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Journal Article
Novel Oligoamine Analogues Inhibit Lysine-Specific Demethylase 1 and Induce Reexpression of Epigenetically Silenced Genes
Huang, Yi, Stewart, Tracy Murray, Wu, Yu, Baylin, Stephen B, Marton, Laurence J, Perkins, Brandy, Jones, Richard J, Woster, Patrick M, Casero, Jr, Robert A
Published in Clinical cancer research (01.12.2009)
Published in Clinical cancer research (01.12.2009)
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Journal Article
Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes
Huang, Yi, Greene, Eriko, Murray Stewart, Tracy, Goodwin, Andrew C, Baylin, Stephen B, Woster, Patrick M, Casero, Robert A. Jr
Published in Proceedings of the National Academy of Sciences - PNAS (08.05.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (08.05.2007)
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Renal Transcriptome and Metabolome in Mice with Principal Cell-Specific Ablation of the Tsc1 Gene: Derangements in Pathways Associated with Cell Metabolism, Growth and Acid Secretion
Zahedi, Kamyar, Barone, Sharon, Brooks, Marybeth, Murray Stewart, Tracy, Casero, Jr, Robert A, Soleimani, Manoocher
Published in International journal of molecular sciences (13.09.2022)
Published in International journal of molecular sciences (13.09.2022)
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Journal Article
Polyamine-Based Nanostructures Share Polyamine Transport Mechanisms with Native Polyamines and Their Analogues: Significance for Polyamine-Targeted Therapy
Holbert, Cassandra E., Foley, Jackson R., Yu, Ao, Murray Stewart, Tracy, Phanstiel, Otto, Oupicky, David, Casero, Robert A.
Published in Medical sciences (Basel) (22.08.2022)
Published in Medical sciences (Basel) (22.08.2022)
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Journal Article
Polyamine catabolism and oxidative damage
Murray Stewart, Tracy, Dunston, Tiffany T., Woster, Patrick M., Casero, Robert A.
Published in The Journal of biological chemistry (30.11.2018)
Published in The Journal of biological chemistry (30.11.2018)
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Journal Article
Polyamines in cancer: integrating organismal metabolism and antitumour immunity
Holbert, Cassandra E., Cullen, Michael T., Casero, Robert A., Stewart, Tracy Murray
Published in Nature reviews. Cancer (01.08.2022)
Published in Nature reviews. Cancer (01.08.2022)
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Journal Article
Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy
Geck, Renee C., Foley, Jackson R., Murray Stewart, Tracy, Asara, John M., Casero, Robert A., Toker, Alex
Published in The Journal of biological chemistry (08.05.2020)
Published in The Journal of biological chemistry (08.05.2020)
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Journal Article
Autophagy induction by exogenous polyamines is an artifact of bovine serum amine oxidase activity in culture serum
Holbert, Cassandra E., Dunworth, Matthew, Foley, Jackson R., Dunston, Tiffany T., Stewart, Tracy Murray, Casero, Robert A.
Published in The Journal of biological chemistry (03.07.2020)
Published in The Journal of biological chemistry (03.07.2020)
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Journal Article
Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout
Steimbach, Raphael R., Herbst-Gervasoni, Corey J., Lechner, Severin, Stewart, Tracy Murray, Klinke, Glynis, Ridinger, Johannes, Géraldy, Magalie N. E., Tihanyi, Gergely, Foley, Jackson R., Uhrig, Ulrike, Kuster, Bernhard, Poschet, Gernot, Casero, Robert A., Médard, Guillaume, Oehme, Ina, Christianson, David W., Gunkel, Nikolas, Miller, Aubry K.
Published in Journal of the American Chemical Society (19.10.2022)
Published in Journal of the American Chemical Society (19.10.2022)
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Journal Article
Effects of Spermine Synthase Deficiency in Mesenchymal Stromal Cells Are Rescued by Upstream Inhibition of Ornithine Decarboxylase
Cressman, Amin, Morales, David, Zhang, Zhenyang, Le, Bryan, Foley, Jackson, Murray-Stewart, Tracy, Genetos, Damian C, Fierro, Fernando A
Published in International journal of molecular sciences (20.02.2024)
Published in International journal of molecular sciences (20.02.2024)
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Journal Article
Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection
Hardbower, Dana M., Asim, Mohammad, Murray-Stewart, Tracy, Casero, Robert A., Verriere, Thomas, Lewis, Nuruddeen D., Chaturvedi, Rupesh, Piazuelo, M. Blanca, Wilson, Keith T.
Published in Amino acids (01.10.2016)
Published in Amino acids (01.10.2016)
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