Diaminopyrimidines, diaminopyridines and diaminopyridazines as histamine H4 receptor modulators
Savall, Brad M., Meduna, Steven P., Tays, Kevin, Cai, Hui, Thurmond, Robin L., McGovern, Patricia, Gaul, Michael, Zhao, Bao-Ping, Edwards, James P.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Structure–activity relationships within a series of caspase inhibitors. Part 2: Heterocyclic warheads
Ullman, Brett R., Aja, Teresa, Chen, Ning, Diaz, Jose-Luis, Gu, Xin, Herrmann, Julia, Kalish, Vincent J., Karanewsky, Donald S., Kodandapani, Lalitha, Krebs, Joseph J., Linton, Steven D., Meduna, Steven P., Nalley, Kip, Robinson, Edward D., Roggo, Silvio P., Sayers, Robert O., Schmitz, Albert, Ternansky, Robert J., Tomaselli, Kevin J., Wu, Joe C.
Published in Bioorganic & medicinal chemistry letters (01.08.2005)
Published in Bioorganic & medicinal chemistry letters (01.08.2005)
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Tricyclic aminopyrimidine histamine H4 receptor antagonists
SAVALL, Brad M, GOMEZ, Laurent, EDWARDS, James P, CHAVEZ, Frank, CURTIS, Michael, MEDUNA, Steven P, KEARNEY, Aaron, DUNFORD, Paul, COWDEN, Jeffery, THURMOND, Robin L, GRICE, Cheryl
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
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Polypharmacology of Small-Molecule Modulators of the 5-Lipoxygenase Activating Protein (FLAP) Observed via a High-throughput Lipidomics Platform
Song, Jiao, Liu, Xuejun, Zhu, Jian, Tootoonchi, Mandana, Keith, John M, Meduna, Steven P, Dvorak, Curt A, Eccles, Wendy, Krawczuk, Paul J, Blevitt, Jonathan M, Wu, Jiejun, Rao, Navin L, Lebsack, Alec D, Milla, Marcos E
Published in Journal of biomolecular screening (01.02.2016)
Published in Journal of biomolecular screening (01.02.2016)
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Triamino pyrimidines and pyridines as histamine H₄ receptor modulators
Meduna, Steven P, Savall, Brad M, Cai, Hui, Edwards, James P, Thurmond, Robin L, McGovern, Patricia M
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
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Pyrazole-based cathepsin S inhibitors with improved cellular potency
Wei, Jianmei, Pio, Barbara A., Cai, Hui, Meduna, Steven P., Sun, Siquan, Gu, Yin, Jiang, Wen, Thurmond, Robin L., Karlsson, Lars, Edwards, James P.
Published in Bioorganic & medicinal chemistry letters (15.10.2007)
Published in Bioorganic & medicinal chemistry letters (15.10.2007)
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Journal Article
Nonpeptidic, Noncovalent Inhibitors of the Cysteine Protease Cathepsin S
Thurmond, Robin L, Beavers, Mary Pat, Cai, Hui, Meduna, Steven P, Gustin, Darin J, Sun, Siquan, Almond, Harold J, Karlsson, Lars, Edwards, James P
Published in Journal of medicinal chemistry (23.09.2004)
Published in Journal of medicinal chemistry (23.09.2004)
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Journal Article
Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors
Gustin, Darin J., Sehon, Clark A., Wei, Jianmei, Cai, Hui, Meduna, Steven P., Khatuya, Haripada, Sun, Siquan, Gu, Yin, Jiang, Wen, Thurmond, Robin L., Karlsson, Lars, Edwards, James P.
Published in Bioorganic & medicinal chemistry letters (15.03.2005)
Published in Bioorganic & medicinal chemistry letters (15.03.2005)
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Journal Article
Oxamyl dipeptide caspase inhibitors developed for the treatment of stroke
Linton, Steven D., Aja, Teresa, Allegrini, Peter R., Deckwerth, Thomas L., Diaz, Jose-Luis, Hengerer, Bastian, Herrmann, Julia, Jahangiri, Kathy G., Kallen, Joerg, Karanewsky, Donald S., Meduna, Steven P., Nalley, Kip, Robinson, Edward D., Roggo, Silvio, Rovelli, Giorgio, Sauter, Andre, Sayers, Robert O., Schmitz, Albert, Smidt, Robert, Ternansky, Robert J., Tomaselli, Kevin J., Ullman, Brett R., Wiessner, Christoph, Wu, Joe C.
Published in Bioorganic & medicinal chemistry letters (17.05.2004)
Published in Bioorganic & medicinal chemistry letters (17.05.2004)
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Journal Article
Structure-activity relationships within a series of caspase inhibitors: Effect of leaving group modifications
ULLMAN, Brett R, AJA, Teresa, ROGGO, Silvio P, SAYERS, Robert O, SCHMITZ, Albert, TERNANSKY, Robert J, TOMASELLI, Kevin J, WU, Joe C, DECKWERTH, Thomas L, DIAZ, Jose-Luis, HERRMANN, Julia, KALISH, Vincent J, KARANEWSKY, Donald S, MEDUNA, Steven P, NALLEY, Kip, ROBINSON, Edward D
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
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Journal Article
Acyl dipeptides as reversible caspase inhibitors. Part 2: Further optimization
LINTON, Steven D, KARANEWSKY, Donald S, WU, Joe C, PHAM, Brian, KODANDAPANI, Lalitha, SMIDT, Robert, DIAZ, Jose-Luis, FRITZ, Lawrence C, VON KROSIGK, U, ROGGO, Silvio, SCHMITZ, Albert, TOMASELLI, Kevin J, TERNANSKY, Robert J, NING CHEN, GUO, Xian, JAHANGIRI, Kathy G, KALISH, Vincent J, MEDUNA, Steven P, ROBINSON, Edward D, ULLMAN, Brett R
Published in Bioorganic & medicinal chemistry letters (21.10.2002)
Published in Bioorganic & medicinal chemistry letters (21.10.2002)
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Lewis Acid-Promoted Reactions of Styrenyl Systems with Benzoquinone Bisimines: New Regioselective Syntheses of Substituted 2-Aryl-2,3-dihydroindoles and 2-Arylindoles
Engler, Thomas A, Meduna, Steven P, LaTessa, Kenneth O, Chai, Wenying
Published in Journal of organic chemistry (29.11.1996)
Published in Journal of organic chemistry (29.11.1996)
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Journal Article
Diaminopyrimidines, diaminopyridines and diaminopyridazines as histamine H-4 receptor modulators
Savall, Brad M., Meduna, Steven P., Tays, Kevin, Cai, Hui, Thurmond, Robin L., McGovern, Patricia, Gaul, Michael, Zhao, Bao-Ping, Edwards, James P.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Journal Article
Tricyclic aminopyrimidine histamine H 4 receptor antagonists
Savall, Brad M., Gomez, Laurent, Chavez, Frank, Curtis, Michael, Meduna, Steven P., Kearney, Aaron, Dunford, Paul, Cowden, Jeffery, Thurmond, Robin L., Grice, Cheryl, Edwards, James P.
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
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Journal Article
The effect of pKa on pyrimidine/pyridine-derived histamine H4 ligands
Savall, Brad M., Meduna, Steven P., Venable, Jennifer, Wei, Jianmei, Smith, Russell C., Hack, Michael D., Thurmond, Robin L., McGovern, Patricia, Edwards, James P.
Published in Bioorganic & medicinal chemistry letters (01.12.2014)
Published in Bioorganic & medicinal chemistry letters (01.12.2014)
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Journal Article
The effect of pK(a) on pyrimidine/pyridine-derived histamine H-4 ligands
Savall, Brad M., Meduna, Steven P., Venable, Jennifer, Wei, Jianmei, Smith, Russell C., Hack, Michael D., Thurmond, Robin L., McGovern, Patricia, Edwards, James P.
Published in Bioorganic & medicinal chemistry letters (01.12.2014)
Published in Bioorganic & medicinal chemistry letters (01.12.2014)
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Journal Article
Diaminopyrimidines, diaminopyridines and diaminopyridazines as histamine H sub(4) receptor modulators
Savall, Brad M, Meduna, Steven P, Tays, Kevin, Cai, Hui, Thurmond, Robin L, McGovern, Patricia, Gaul, Michael, Zhao, Bao-Ping, Edwards, James P
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Journal Article
The effect of pK sub(a) on pyrimidine/pyridine-derived histamine H sub(4) ligands
Savall, Brad M, Meduna, Steven P, Venable, Jennifer, Wei, Jianmei, Smith, Russell C, Hack, Michael D, Thurmond, Robin L, McGovern, Patricia, Edwards, James P
Published in Bioorganic & medicinal chemistry letters (01.12.2014)
Published in Bioorganic & medicinal chemistry letters (01.12.2014)
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