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Synthesis of many different types of organic small molecules using one automated process

Synthesis of many different types of organic small molecules using one automated process

by Li, Junqi, Ballmer, Steven G., Gillis, Eric P., Fujii, Seiko, Schmidt, Michael J., Palazzolo, Andrea M. E., Lehmann, Jonathan W., Morehouse, Greg F., Burke, Martin D.
Published in Science (American Association for the Advancement of Science) (13.03.2015)

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Journal Article

ChemInform Abstract: Synthesis of Many Different Types of Organic Small Molecules Using One Automated Process

ChemInform Abstract: Synthesis of Many Different Types of Organic Small Molecules Using One Automated Process

by Li, Junqi, Ballmer, Steven G., Gillis, Eric P., Fujii, Seiko, Schmidt, Michael J., Palazzolo, Andrea M. E., Lehmann, Jonathan W., Morehouse, Greg F., Burke, Martin D.
Published in ChemInform (01.08.2015)

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Journal Article

Solid forms of {6-[(2-amino-3-chloropyridin-4-yl)sulfanyl]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5]decan-8-yl]-5-methylpyrazin-2-yl} methanol, a SHP2 inhibitor

Solid forms of {6-[(2-amino-3-chloropyridin-4-yl)sulfanyl]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5]decan-8-yl]-5-methylpyrazin-2-yl} methanol, a SHP2 inhibitor

by Ballmer, Steven G, Li, Shaoling
Year of Publication 11.01.2022

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by BALLMER, Steven G, HUANG, Xiaojun, LI, Shaoling
Year of Publication 30.05.2024

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Patent

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, A SHP2 INHIBITOR

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, A SHP2 INHIBITOR

by BALLMER, Steven G, LI, Shaoling
Year of Publication 22.09.2022

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by BALLMER, Steven G, HUANG, Xiaojun, LI, Shaoling
Year of Publication 14.02.2024

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Patent

FORMES SOLIDES DE (6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-MÉTHYL-2-OXA-8-AZASPIRO [4,5]DÉCAN-8-YL]-5-MÉTHYLPYRAZIN-2-YL)MÉTHANOL, UN INHIBITEUR DE SHP2

FORMES SOLIDES DE (6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-MÉTHYL-2-OXA-8-AZASPIRO [4,5]DÉCAN-8-YL]-5-MÉTHYLPYRAZIN-2-YL)MÉTHANOL, UN INHIBITEUR DE SHP2

by BALLMER, Steven G, LI, Shaoling
Year of Publication 13.04.2022

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Patent

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

by BALLMER, Steven G, LI, Shaoling
Year of Publication 13.04.2022

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by BALLMER, Steven G, HUANG, Xiaojun, LI, Shaoling
Year of Publication 16.11.2023

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Patent

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

by BALLMER, Steven G, LI, Shaoling
Year of Publication 30.12.2021

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Patent

Solid forms of {6-[(2-amino-3-chloropyridin-4-yl)sulfanyl]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-5-methylpyrazin-2-yl}methanol, an SHP2 inhibitor

Solid forms of {6-[(2-amino-3-chloropyridin-4-yl)sulfanyl]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-5-methylpyrazin-2-yl}methanol, an SHP2 inhibitor

by BALLMER, Steven G, LI, Shaoling
Year of Publication 09.12.2021

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Patent

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

by BALLMER, Steven G, LI, Shaoling
Year of Publication 19.08.2021

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by BALLMER, Steven G, HUANG, Xiaojun, LI, Shaoling
Year of Publication 09.03.2023

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by BALLMER, Steven G, HUANG, Xiaojun, LI, Shaoling
Year of Publication 22.12.2022

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by HUANG, XIAOJUN, LI, SHAOLING, BALLMER, STEVEN G
Year of Publication 13.10.2022

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by BALLMER, Steven G, HUANG, Xiaojun, LI, Shaoling
Year of Publication 13.10.2022

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Patent

PROCESS FOR PREPARING SHP2 INHIBITORS

PROCESS FOR PREPARING SHP2 INHIBITORS

by BALLMER, Steven G, ARNOLD, Mickaël, LI, Shaoling, GARNIER, Céline, LESZCZAK, Jean-Pierre
Year of Publication 06.06.2024

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Patent

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

by LI, SHAOLING, BALLMER, STEVEN G
Year of Publication 10.12.2020

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Patent

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

by BALLMER, Steven G, LI, Shaoling
Year of Publication 10.12.2020

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Patent

PROCESS FOR PREPARING SHP2 INHIBITORS

PROCESS FOR PREPARING SHP2 INHIBITORS

by BALLMER, Steven G, ARNOLD, Mickaël, LI, Shaoling, GARNIER, Céline, LESZCZAK, Jean-Pierre
Year of Publication 25.10.2023

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Patent