Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90
BARTA, Thomas E, VEAL, James M, BARABASZ, Amy F, FOLEY, Briana E, OTTO, James, HALL, Steven E, RICE, John W, PARTRIDGE, Jeffrey M, FADDEN, R. Patrick, WEI MA, JENKS, Matthew, LIFENG GENG, HANSON, Gunnar J, HUANG, Kenneth H
Published in Bioorganic & medicinal chemistry (15.06.2008)
Published in Bioorganic & medicinal chemistry (15.06.2008)
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A new ligation method for N-terminal tryptophan-containing peptides using the Pictet–Spengler reaction
Li, Xianfeng, Zhang, Lianshan, Hall, Steven E, Tam, James P
Published in Tetrahedron letters (29.05.2000)
Published in Tetrahedron letters (29.05.2000)
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Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents
Huang, Kenneth H, Veal, James M, Fadden, R. Patrick, Rice, John W, Eaves, Jeron, Strachan, Jon-Paul, Barabasz, Amy F, Foley, Briana E, Barta, Thomas E, Ma, Wei, Silinski, Melanie A, Hu, Mei, Partridge, Jeffrey M, Scott, Anisa, DuBois, Laura G, Freed, Tiffany, Steed, Paul M, Ommen, Andy J, Smith, Emilie D, Hughes, Philip F, Woodward, Angela R, Hanson, Gunnar J, McCall, W. Stephen, Markworth, Christopher J, Hinkley, Lindsay, Jenks, Matthew, Geng, Lifeng, Lewis, Meredith, Otto, James, Pronk, Bert, Verleysen, Katleen, Hall, Steven E
Published in Journal of medicinal chemistry (23.07.2009)
Published in Journal of medicinal chemistry (23.07.2009)
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Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis
Rice, John W., Veal, James M., Fadden, R. Patrick, Barabasz, Amy F., Partridge, Jeffrey M., Barta, Thomas E., Dubois, Laura G., Huang, Kenneth H., Mabbett, Sarah R., Silinski, Melanie A., Steed, Paul M., Hall, Steven E.
Published in Arthritis and rheumatism (01.12.2008)
Published in Arthritis and rheumatism (01.12.2008)
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Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90
Huang, Kenneth H., Barta, Thomas E., Rice, John W., Smith, Emilie D., Ommen, Andy J., Ma, Wei, Veal, James M., Fadden, R. Patrick, Barabasz, Amy F., Foley, Briana E., Hughes, Philip F., Hanson, Gunnar J., Markworth, Christopher J., Silinski, Melanie, Partridge, Jeffrey M., Steed, Paul M., Hall, Steven E.
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
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Novel carbazole and acyl-indole antimitotics
Barta, Thomas E., Barabasz, Amy F., Foley, Briana E., Geng, Lifeng, Hall, Steven E., Hanson, Gunnar J., Jenks, Matthew, Ma, Wei, Rice, John W., Veal, James
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
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(S)-13-[(Dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21-dimetheno- 1H,13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-dione (LY333531) and Related Analogues: Isozyme Selective Inhibitors of Protein Kinase Cβ
Jirousek, Michael R, Gillig, James R, Gonzalez, Cecile M, Heath, William F, McDonald, John H, Neel, David A, Rito, Christopher J, Singh, Upinder, Stramm, Lawrence E, Melikian-Badalian, Anita, Baevsky, Matthew, Ballas, Lawrence M, Hall, Steven E, Winneroski, Leonard L, Faul, Margaret M
Published in Journal of medicinal chemistry (05.07.1996)
Published in Journal of medicinal chemistry (05.07.1996)
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Synthesis and Protein Kinase Inhibitory Activity of Balanol Analogues with Modified Benzophenone Subunits
Lampe, John W, Biggers, Christopher K, Defauw, Jean M, Foglesong, Robert J, Hall, Steven E, Heerding, Julia M, Hollinshead, Sean P, Hu, Hong, Hughes, Philip F, Jagdmann, G. Erik, Johnson, Mary George, Lai, Yen-Shi, Lowden, Christopher T, Lynch, Michael P, Mendoza, José S, Murphy, Marcia M, Wilson, Joseph W, Ballas, Lawrence M, Carter, Kiyomi, Darges, James W, Davis, Jefferson E, Hubbard, Frederick R, Stamper, Mark L
Published in Journal of medicinal chemistry (06.06.2002)
Published in Journal of medicinal chemistry (06.06.2002)
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Solid-Phase Synthesis of 1,2,3,4-Tetrahydro-β-carboline-Containing Peptidomimetics
Li, Xianfeng, Zhang, Lianshan, Zhang, Wei, Hall, Steven E, Tam, James P
Published in Organic letters (05.10.2000)
Published in Organic letters (05.10.2000)
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9,11-Epoxy-9-homo-14-thiaprost-5-enoic acid derivatives: potent thromboxane A2 antagonists
Hall, Steven E, Han, Wen Ching, Harris, Don N, Hedberg, Anders, Ogletree, Martin L
Published in Journal of medicinal chemistry (01.05.1989)
Published in Journal of medicinal chemistry (01.05.1989)
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Molecular design and structure–Activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664
Das, Jagabandhu, Kimball, S.David, Hall, Steven E., Han, Wen-Ching, Iwanowicz, Edwin, Lin, James, Moquin, Robert V., Reid, Joyce A., Sack, John S., Malley, Mary F., Chang, Chiehying Y., Chong, Saeho, Wang-Iverson, David B., Roberts, Daniel G.M., Seiler, Steven M., Schumacher, William A., Ogletree, Martin L.
Published in Bioorganic & medicinal chemistry letters (07.01.2002)
Published in Bioorganic & medicinal chemistry letters (07.01.2002)
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Synthesis and Protein Kinase C Inhibitory Activities of Balanol Analogs with Replacement of the Perhydroazepine Moiety
Lai, Yen-Shi, Mendoza, José S, Jagdmann, G. Erik, Menaldino, David S, Biggers, Christopher K, Heerding, Julia M, Wilson, Joseph W, Hall, Steven E, Jiang, Jack B, Janzen, William P, Ballas, Lawrence M
Published in Journal of medicinal chemistry (17.01.1997)
Published in Journal of medicinal chemistry (17.01.1997)
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Application of Chemoproteomics to Drug Discovery: Identification of a Clinical Candidate Targeting Hsp90
Fadden, Patrick, Huang, Kenneth H., Veal, James M., Steed, Paul M., Barabasz, Amy F., Foley, Briana, Hu, Mei, Partridge, Jeffrey M., Rice, John, Scott, Anisa, Dubois, Laura G., Freed, Tiffany A., Silinski, Melanie A. Rehder, Barta, Thomas E., Hughes, Philip F., Ommen, Andy, Ma, Wei, Smith, Emilie D., Spangenberg, Angela Woodward, Eaves, Jeron, Hanson, Gunnar J., Hinkley, Lindsay, Jenks, Matthew, Lewis, Meredith, Otto, James, Pronk, Gijsbertus J., Verleysen, Katleen, Haystead, Timothy A., Hall, Steven E.
Published in Chemistry & biology (30.07.2010)
Published in Chemistry & biology (30.07.2010)
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D-Ala-D-X ligases: evaluation of D-alanyl phosphate intermediate by MIX, PIX and rapid quench studies
Healy, V L, Mullins, L S, Li, X, Hall, S E, Raushel, F M, Walsh, C T
Published in Chemistry & biology (01.07.2000)
Published in Chemistry & biology (01.07.2000)
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Synthesis of bisindolylmaleimide macrocycles
Jirousek, Michael R, Gillig, James R, Neel, David A, Rito, Christopher J, O'Bannon, Douglas, Heath, William F, McDonald, John H, Faul, Margaret M, Winneroski, Leonard L, Melikian-Badalian, Anita, Baevsky, Matthew, Ballas, Larwence M, Hall, Steven E
Published in Bioorganic & medicinal chemistry letters (21.09.1995)
Published in Bioorganic & medicinal chemistry letters (21.09.1995)
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Interphenylene 7-oxabicyclo[2.2.1]heptane oxazoles. Highly potent, selective, and long-acting thromboxane A2 receptor antagonists
Misra, Raj N, Brown, Baerbel R, Sher, Philip M, Patel, Manorama M, Hall, Steven E, Han, Wen Ching, Barrish, Joel C, Kocy, Octavian, Harris, Don N
Published in Journal of medicinal chemistry (01.05.1993)
Published in Journal of medicinal chemistry (01.05.1993)
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