An Imidazopiperidine Series of CCR5 Antagonists for the Treatment of HIV: The Discovery of N-{(1S)-1-(3-Fluorophenyl)-3-[(3-endo)-3-(5-isobutyryl-2-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]propyl}acetamide (PF-232798)
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Published in Journal of medicinal chemistry (13.01.2011)
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Published in Tetrahedron letters (30.11.2011)
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Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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SAR of a series of inhaled A(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data
Mantell, Simon J, Stephenson, Peter T, Monaghan, Sandra M, Maw, Graham N, Trevethick, Michael A, Yeadon, Michael, Walker, Don K, Selby, Matthew D, Batchelor, David V, Rozze, Stuart, Chavaroche, Helene, Lemaitre, Arnaud, Wright, Karen N, Whitlock, Lynsey, Stuart, Emilio F, Wright, Patricia A, Macintyre, Fiona
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Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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Synthesis of Novel 2-Cyano-7-deaza-8-azapurine- and 2-Cyano-8-azapurine-Derived Nucleosides
Wainwright, Philip, Maddaford, Adrian, Simms, Michael, Forrest, Neil, Glen, Rebecca, Hart, James, Zhang, Xiurong, Pryde, David C., Stephenson, Peter T., Middleton, Donald S., Guyot, Thierry, Sutton, Scott C.
Published in Synlett (01.08.2011)
Published in Synlett (01.08.2011)
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Synthesis and Biological Evaluation of Acyclic Phosphonic Acid Nucleoside Derivatives
Wainwright, Philip, Maddaford, Adrian, Zhang, Xiurong, Billington, Helen, Leese, David, Glen, Rebecca, Pryde, David C., Middleton, Donald S., Stephenson, Peter T., Sutton, Scott
Published in Nucleosides, nucleotides & nucleic acids (02.09.2013)
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Discovery of a small molecule inhibitor through interference with the gp120–CD4 interaction
Williams, David H., Adam, Fiona, Fenwick, David R., Fok-Seang, Juin, Gardner, Iain, Hay, Duncan, Jaiessh, Rawal, Middleton, Donald S., Mowbray, Charles E., Parkinson, Tanya, Perros, Manos, Pickford, Christopher, Platts, Michelle, Randall, Amy, Siddle, Daniel, Stephenson, Peter T., Tran, Thien-Duc, Vuong, Hannah
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
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Design and optimisation of potent gp120-CD4 inhibitors
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Published in Bioorganic & medicinal chemistry letters (01.09.2009)
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
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The design and discovery of novel amide CCR5 antagonists
Pryde, David C., Corless, Martin, Fenwick, David R., Mason, Helen J., Stammen, Blanda C., Stephenson, Peter T., Ellis, David, Bachelor, David, Gordon, David, Barber, Christopher G., Wood, Anthony, Middleton, Donald S., Blakemore, David C., Parsons, Gemma C., Eastwood, Rachel, Platts, Michelle Y., Statham, Keith, Paradowski, Kerry A., Burt, Catherine, Klute, Wolfgang
Published in Bioorganic & medicinal chemistry letters (15.02.2009)
Published in Bioorganic & medicinal chemistry letters (15.02.2009)
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Inhaled adenosine A2A receptor agonists for the treatment of chronic obstructive pulmonary disease
MANTELL, Simon J, STEPHENSON, Peter T, BATCHELOR, David V, ROZZE, Stuart, CHAVAROCHE, Helene, HOBSON, Tim J, DODD, Peter G, LEMAITRE, Arnaud, WRIGHT, Karen N, STUART, Emilio F, MONAGHAN, Sandra M, MAW, Graham N, TREVETHICK, Michael A, YEADON, Michael, KEIR, Ruth F, WALKER, Don K, JONES, Rhys M, SELBY, Matthew D
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
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Inhaled adenosine A(2A) receptor agonists for the treatment of chronic obstructive pulmonary disease
Mantell, Simon J, Stephenson, Peter T, Monaghan, Sandra M, Maw, Graham N, Trevethick, Michael A, Yeadon, Michael, Keir, Ruth F, Walker, Don K, Jones, Rhys M, Selby, Matthew D, Batchelor, David V, Rozze, Stuart, Chavaroche, Helene, Hobson, Tim J, Dodd, Peter G, Lemaitre, Arnaud, Wright, Karen N, Stuart, Emilio F
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
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Cyclisation of carbinyl radicals onto imines and hydrazones
Bowman, W.Russell, Stephenson, Peter T., Terrett, Nicholas K., Young, Adrian R.
Published in Tetrahedron letters (01.08.1994)
Published in Tetrahedron letters (01.08.1994)
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Syntheses of the racemic jaborandi alkaloids pilocarpine, isopilocarpine and pilosinine
Davies, Stephen G., Roberts, Paul M., Stephenson, Peter T., Thomson, James E.
Published in Tetrahedron letters (01.07.2009)
Published in Tetrahedron letters (01.07.2009)
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SAR of a series of inhaled A sub(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data
Mantell, Simon J, Stephenson, Peter T, Monaghan, Sandra M, Maw, Graham N, Trevethick, Michael A, Yeadon, Michael, Walker, Don K, Selby, Matthew D, Batchelor, David V, Rozze, Stuart, Chavaroche, Helene, Lemaitre, Arnaud, Wright, Karen N, Whitlock, Lynsey, Stuart, Emilio F, Wright, Patricia A, Macintyre, Fiona
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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Radical cyclisations of imines and hydrazones
Russell Bowman, W., Stephenson, Peter T., Terrett, Nicholas K., Young, Adrian R.
Published in Tetrahedron (17.07.1995)
Published in Tetrahedron (17.07.1995)
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Journal Article
Inhaled adenosine A sub(2A) receptor agonists for the treatment of chronic obstructive pulmonary disease
Mantell, Simon J, Stephenson, Peter T, Monaghan, Sandra M, Maw, Graham N, Trevethick, Michael A, Yeadon, Michael, Keir, Ruth F, Walker, Don K, Jones, Rhys M, Selby, Matthew D, Batchelor, David V, Rozze, Stuart, Chavaroche, Helene, Hobson, Tim J, Dodd, Peter G, Lemaitre, Arnaud, Wright, Karen N, Stuart, Emilio F
Published in Bioorganic & medicinal chemistry (01.02.2008)
Published in Bioorganic & medicinal chemistry (01.02.2008)
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Journal Article
Inhaled adenosine A 2A receptor agonists for the treatment of chronic obstructive pulmonary disease
Mantell, Simon J., Stephenson, Peter T., Monaghan, Sandra M., Maw, Graham N., Trevethick, Michael A., Yeadon, Michael, Keir, Ruth F., Walker, Don K., Jones, Rhys M., Selby, Matthew D., Batchelor, David V., Rozze, Stuart, Chavaroche, Helene, Hobson, Tim J., Dodd, Peter G., Lemaitre, Arnaud, Wright, Karen N., Stuart, Emilio F.
Published in Bioorganic & medicinal chemistry letters (2008)
Published in Bioorganic & medicinal chemistry letters (2008)
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A flexible, efficient synthesis of (+/-)-carbocyclic phosphonic acid nucleoside derivatives
Wainwright, P, Maddaford, A, Bissell, R, Fisher, R, Leese, D, Lund, A, Runcie, K, Dragovich, PS, Gonzalez, J, Kung, PP, Middleton, DS, Pryde, DC, Stephenson, PT, Utton, SCS
Published in Synlett (21.03.2005)
Published in Synlett (21.03.2005)
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