IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration
Brand, Stephan, Beigel, Florian, Olszak, Torsten, Zitzmann, Kathrin, Eichhorst, Sören T, Otte, Jan-Michel, Diepolder, Helmut, Marquardt, Andreas, Jagla, Wolfgang, Popp, Andreas, Leclair, Stéphane, Herrmann, Karin, Seiderer, Julia, Ochsenkühn, Thomas, Göke, Burkhard, Auernhammer, Christoph J, Dambacher, Julia
Published in American journal of physiology: Gastrointestinal and liver physiology (01.04.2006)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.04.2006)
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Journal Article
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8 + T cells
Codarri Deak, Laura, Nicolini, Valeria, Hashimoto, Masao, Karagianni, Maria, Schwalie, Petra C, Lauener, Laura, Varypataki, Eleni Maria, Richard, Marine, Bommer, Esther, Sam, Johannes, Joller, Stefanie, Perro, Mario, Cremasco, Floriana, Kunz, Leo, Yanguez, Emilio, Hüsser, Tamara, Schlenker, Ramona, Mariani, Marisa, Tosevski, Vinko, Herter, Sylvia, Bacac, Marina, Waldhauer, Inja, Colombetti, Sara, Gueripel, Xavier, Wullschleger, Stephan, Tichet, Melanie, Hanahan, Douglas, Kissick, Haydn T, Leclair, Stephane, Freimoser-Grundschober, Anne, Seeber, Stefan, Teichgräber, Volker, Ahmed, Rafi, Klein, Christian, Umaña, Pablo
Published in Nature (London) (06.10.2022)
Published in Nature (London) (06.10.2022)
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Journal Article
Abstract 7534: Tobemstomig, a novel bispecific checkpoint inhibitory antibody to preferentially block PD-1 and LAG-3 on CD8 TILs over Tregs
Codarri-Deak, Laura, Weber, Patrick Aaron, Nicolini, Valeria, Klein, Christian, Umana, Pablo, Seeber, Stefan, Perro, Mario, Leclair, Stephane
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract 2270: RG7769 (PD1-TIM3), a novel heterodimeric avidity-driven T cell specific PD-1/TIM-3 bispecific antibody lacking Fc-mediated effector functions for dual checkpoint inhibition to reactivate dysfunctional T cells
Deak, Laura Laura Codarri, Seeber, Stefan, Perro, Mario, Weber, Patrick, Lauener, Laura, Chen, Standford, Offner, Sonja, Dengl, Stefan, Hesse, Friederike, Zwick, Adrian, Boettger, Marco, Bujotzek, Alexander, Benz, Jörg, Georges, Guy, Fertig, Georg, Lifke, Valeria, Fischer, Jens, Leclair, Stephane, Levitsky, Victor, Canamero, Marta, Lindner, Juha, Colombetti, Sara, Bendels, Stefanie, Boetsch, Christophe, Fueth, Matthias, Muecke, Merlind, Kao, Henry, Umana, Pablo, Klein, Christian
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 6709: P329G-Engager: A novel universal antibody-based adaptor platform for cancer immunotherapy
Surowka, Marlena, Hutter-Karakoc, Idil, Darowski, Diana, Claus, Christina, Koller, Claudia Ferrara, Freimoser-Grundschober, Anne, Hofer, Thomas, Sobieniecki, Andrzej, Assisi, Denis, Leclair, Stephane, Moessner, Ekkehard, Umaña, Pablo, Amann, Maria, Klein, Christian
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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α-Radioimmunotherapy with ²¹³Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma
Teiluf, Katharina, Seidl, Christof, Blechert, Birgit, Gaertner, Florian C, Gilbertz, Klaus-Peter, Fernandez, Vanesa, Bassermann, Florian, Endell, Jan, Boxhammer, Rainer, Leclair, Stephane, Vallon, Mario, Aichler, Michaela, Feuchtinger, Annette, Bruchertseifer, Frank, Morgenstern, Alfred, Essler, Markus
Published in Oncotarget (10.03.2015)
Published in Oncotarget (10.03.2015)
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RG6234: A Novel 2:1 GPRC5D T Cell Bispecific Antibody Exhibits Best in Class Potential for the Treatment of Multiple Myeloma As a Monotherapy and in Combination
Eckmann, Jan, Fauti, Tanja, Zabaleta, Aintzane, Blanco, Laura, Kassem, Sahar, Carrié, Nadege, Lorenz, Stefan, Carpy, Alejandro, Christopeit, Tony, Fertig, Georg, Bernasconi, Luise, Biehl, Marlene, Diggelmann, Sarah, Knobloch, Melanie, Mayoux, Maud, Dumontet, Charles, Paiva, Bruno, Martinet, Ludovic, Leclair, Stéphane, Xu, Wei, Klein, Christian, Umaña, Pablo
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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NOVEL BISPECIFIC ANTIGEN BINDING MOLECULES CAPABLE OF SPECIFIC BINDING TO CD40 AND TO FAP
LECLAIR, Stephane, SUM, Eva Carina, RAPP, Moritz, GEORGES, Guy, KLEIN, Christian, DUERR, Harald, UMAÑA, Pablo, BRUENKER, Peter, BUJOTZEK, Alexander, TRUMPELLER, Christine
Year of Publication 31.07.2024
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Year of Publication 31.07.2024
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AGONISTIC LTBR ANTIBODIES AND BISPECIFIC ANTIBODIES COMPRISING THEM
KUNZ, Leo Frederik, LECLAIR, Stephane, MUNDIGL, Olaf, NIKOLOV, Miroslav, HOSSE, Ralf, BIANCHI, Roberta, GEORGES, Guy, MENDE, Fanny, BRYDON, Michelle Victoria, DUERR, Harald, BORMANN, Felix, DENGL, Stefan, LEISIBACH, Desirée, HANISCH, Lydia Jasmin, HEIDRICH, Monika, UMAÑA, Pablo, WAGNER, Cornelia
Year of Publication 13.06.2024
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Year of Publication 13.06.2024
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IMMUNE ACTIVATING Fc DOMAIN BINDING MOLECULES
Darowski, Diana, Amann, Maria, Herter, Sylvia, Bransi, Ali, Codarri Deak, Laura, Fauti, Tanja, Ferrara Koller, Claudia, Hofer, Thomas, Lauener, Laura, Neumann, Christiane, Surówka, Marlena, Moessner, Ekkehard, Carpy Gutierrez Cirlos, Alejandro, Claus, Christina, Leclair, Stephane, Klein, Christian, Umaña, Pablo, Freimoser-Grundschober, Anne
Year of Publication 08.02.2024
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Year of Publication 08.02.2024
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TREATMENT FOR RHEUMATOID ARTHRITIS
LECLAIR, Stephane, ROSPORT, Kai, SHEBL, Amgad, DUCATA, Daniela Della, STEIDL, Stefan, BROCKS, Bodo, HARTLE, Stefan
Year of Publication 06.05.2021
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Year of Publication 06.05.2021
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