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Separable neural mechanisms for the pleiotropic association of copy number variants with neuropsychiatric traits
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Design, Synthesis, and Pharmacological Characterization of N- and O‑Substituted 5,6,7,8-Tetrahydro‑4H‑isoxazolo[4,5‑d]azepin-3-ol Analogues: Novel 5‑HT2A/5-HT2C Receptor Agonists with Pro-Cognitive Properties
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CNVs conferring risk of autism or schizophrenia affect cognition in controls
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Published in Nature (London) (16.01.2014)
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Chemo-Enzymatic Synthesis of (2S,4R)-2-Amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic Acid: A Novel Selective Inhibitor of Human Excitatory Amino Acid Transporter Subtype 2
Sagot, Emanuelle, Jensen, Anders A, Pickering, Darryl S, Pu, Xiaosui, Umberti, Michelle, Stensbøl, Tine B, Nielsen, Birgitte, Assaf, Zeinab, Aboab, Bétina, Bolte, Jean, Gefflaut, Thierry, Bunch, Lennart
Published in Journal of medicinal chemistry (24.07.2008)
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Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: a study in male mice
Didriksen, Michael, PhD, Fejgin, Kim, PhD, Birknow, Michelle R., MSc, Larsen, Peter H., PhD, Lauridsen, Jes B., PhD, Nielsen, Vibeke, BSc, Kallunki, Pekka, PhD, Christensen, Kenneth V., PhD, Stensbøl, Tine B., PhD, Egebjerg, Jan, PhD, Nielsen, Jacob, PhD, Nilsson, Simon R.O., PhD, Grayton, Hannah M., PhD, Gastambide, Francois, PhD, Celada, Pau, PhD, Artigas, Francesc, PhD, Santana, Noemi, PhD, Werge, Thomas M., PhD, Bastlund, Jesper F., PhD
Published in Journal of psychiatry & neuroscience (01.01.2017)
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A mouse model of the 15q13.3 microdeletion syndrome shows prefrontal neurophysiological dysfunctions and attentional impairment
Nilsson, Simon R. O., Celada, Pau, Fejgin, Kim, Thelin, Jonas, Nielsen, Jacob, Santana, Noemí, Heath, Christopher J., Larsen, Peter H., Nielsen, Vibeke, Kent, Brianne A., Saksida, Lisa M., Stensbøl, Tine B., Robbins, Trevor W., Bastlund, Jesper F., Bussey, Timothy J., Artigas, Francesc, Didriksen, Michael
Published in Psychopharmacologia (01.06.2016)
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The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT 3 receptor expressing interneurons: An in vitro study in rat hippocampus slices
Dale, Elena, Grunnet, Morten, Pehrson, Alan L, Frederiksen, Kristen, Larsen, Peter H, Nielsen, Jacob, Stensbøl, Tine B, Ebert, Bjarke, Yin, Haolan, Lu, Dunguo, Liu, Huiquing, Jensen, Thomas N, Yang, Charles R, Sanchez, Connie
Published in Brain research (15.06.2018)
Published in Brain research (15.06.2018)
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Assessing the Cognitive Translational Potential of a Mouse Model of the 22q11.2 Microdeletion Syndrome
Nilsson, Simon Ro, Fejgin, Kim, Gastambide, Francois, Vogt, Miriam A, Kent, Brianne A, Nielsen, Vibeke, Nielsen, Jacob, Gass, Peter, Robbins, Trevor W, Saksida, Lisa M, Stensbøl, Tine B, Tricklebank, Mark D, Didriksen, Michael, Bussey, Timothy J
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Published in Cerebral cortex (New York, N.Y. 1991) (01.10.2016)
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Novel 1-Hydroxyazole Bioisosteres of Glutamic Acid. Synthesis, Protolytic Properties, and Pharmacology
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Published in Journal of medicinal chemistry (03.01.2002)
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2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid: Resolution, absolute stereochemistry and enantiopharmacology at glutamate receptors
JOHANSEN, Tommy N, JANIN, Yves L, NIELSEN, Birgitte, FRYDENVANG, Karla, BRÄUNER-OSBORNE, Hans, STENSBØL, Tine B, VOGENSEN, Stine B, MADSEN, Ulf, KROGSGAARD-LARSEN, Povl
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New 4‑Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III
Huynh, Tri H. V, Erichsen, Mette N, Tora, Amélie S, Goudet, Cyril, Sagot, Emmanuelle, Assaf, Zeinab, Thomsen, Christian, Brodbeck, Robb, Stensbøl, Tine B, Bjørn-Yoshimoto, Walden E, Nielsen, Birgitte, Pin, Jean-Philippe, Gefflaut, Thierry, Bunch, Lennart
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(S)-Homo-AMPA, a Specific Agonist at the mGlu6 Subtype of Metabotropic Glutamic Acid Receptors
Ahmadian, Haleh, Nielsen, Birgitte, Bräuner-Osborne, Hans, Johansen, Tommy N, Stensbøl, Tine B, Sløk, Frank A, Sekiyama, Naohiro, Nakanishi, Shigetada, Krogsgaard-Larsen, Povl, Madsen, Ulf
Published in Journal of medicinal chemistry (24.10.1997)
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4-aryl-5-(4-piperidyl)-3-isoxazolol GABA(A) antagonists: Synthesis, pharmacology, and structure-activity relationships
Frolund, Bente, Jensen, Lars S., Storustovu, Signe I., Stensbol, Tine B., Ebert, Bjarke, Kehler, Jan, Krogsgaard-Larsen, Povl, Liljefors, Tommy
Published in Journal of medicinal chemistry (19.04.2007)
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Plaque Deposition Dependent Decrease in 5-HT2A Serotonin Receptor in AβPPswe/PS1dE9 Amyloid Overexpressing Mice
Holm, Peter, Ettrup, Anders, Klein, Anders B., Santini, Martin A., El-Sayed, Mona, Elvang, Anders B., Stensbøl, Tine B., Mikkelsen, Jens D., Knudsen, Gitte M., Aznar, Susana
Published in Journal of Alzheimer's disease (13.06.2010)
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Novel Class of Potent 4-Arylalkyl Substituted 3-Isoxazolol GABAA Antagonists: Synthesis, Pharmacology, and Molecular Modeling
Frølund, Bente, Jørgensen, Anne T, Tagmose, Lena, Stensbøl, Tine B, Vestergaard, Henrik T, Engblom, Christine, Kristiansen, Uffe, Sanchez, Connie, Krogsgaard-Larsen, Povl, Liljefors, Tommy
Published in Journal of medicinal chemistry (06.06.2002)
Published in Journal of medicinal chemistry (06.06.2002)
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Novel class of potent 4-arylalkyl substituted 3-isoxazolol GABA(A) antagonists: Synthesis, pharmacology, and molecular modeling
Frolund, B, Jorgensen, AT, Tagmose, L, Stensbol, TB, Vestergaard, HT, Engblom, C, Kristiansen, U, Sanchez, C, Krogsgaard-Larsen, P, Liljefors, T
Published in Journal of medicinal chemistry (06.06.2002)
Published in Journal of medicinal chemistry (06.06.2002)
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