Discovery of 5′′-Chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2′:5′,3′′-terpyridine-3′-carboxamide (MK-1064): A Selective Orexin 2 Receptor Antagonist (2-SORA) for the Treatment of Insomnia
Roecker, Anthony J., Mercer, Swati P., Schreier, John D., Cox, Christopher D., Fraley, Mark E., Steen, Justin T., Lemaire, Wei, Bruno, Joseph G., Harrell, C. Meacham, Garson, Susan L., Gotter, Anthony L., Fox, Steven V., Stevens, Joanne, Tannenbaum, Pamela L., Prueksaritanont, Thomayant, Cabalu, Tamara D., Cui, Donghui, Stellabott, Joyce, Hartman, George D., Young, Steven D., Winrow, Christopher J., Renger, John J., Coleman, Paul J.
Published in ChemMedChem (01.02.2014)
Published in ChemMedChem (01.02.2014)
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Discovery of MK-3697: A selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia
Roecker, Anthony J., Reger, Thomas S., Mattern, M. Christa, Mercer, Swati P., Bergman, Jeffrey M., Schreier, John D., Cube, Rowena V., Cox, Christopher D., Li, Dansu, Lemaire, Wei, Bruno, Joseph G., Harrell, C. Meacham, Garson, Susan L., Gotter, Anthony L., Fox, Steven V., Stevens, Joanne, Tannenbaum, Pamela L., Prueksaritanont, Thomayant, Cabalu, Tamara D., Cui, Donghui, Stellabott, Joyce, Hartman, George D., Young, Steven D., Winrow, Christopher J., Renger, John J., Coleman, Paul J.
Published in Bioorganic & medicinal chemistry letters (15.10.2014)
Published in Bioorganic & medicinal chemistry letters (15.10.2014)
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Effect of TPGS surfactant on dissolution sensitivity of a poorly water-soluble drug using high-shear wet granulation
Sotthivirat, Sutthilug, Ramesh, Rishi, Wasylaschuk, Walter, Bottone, Cory, Xia, Binfeng, Stellabott, Joyce, McNevin, Michael, Skomski, Daniel, Brown, Chad
Published in Powder technology (20.09.2020)
Published in Powder technology (20.09.2020)
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Understanding the process-product-performance interplay of spray dried drug-polymer systems through complete structural and chemical characterization of single spray dried particles
Poozesh, Sadegh, Setiawan, Nico, Arce, Freddy, Sundararajan, Pavithra, Rocca, Joseph Della, Rumondor, Alfred, Wei, Douglas, Wenslow, Robert, Xi, Hanmi, Zhang, Shawn, Stellabott, Joyce, Su, Yongchao, Moser, Justin, Marsac, Patrick Jules
Published in Powder technology (01.10.2017)
Published in Powder technology (01.10.2017)
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Comparing Dog and Human Intestinal Fluids: Implications on Solubility and Biopharmaceutical Risk Assessment
Walsh, Paul L., Stellabott, Joyce, Nofsinger, Rebecca, Xu, Wei, Levorse, Dorothy, Galipeau, Kendra, Kesisoglou, Filippos
Published in AAPS PharmSciTech (01.05.2017)
Published in AAPS PharmSciTech (01.05.2017)
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Discovery of [(2R,5R)-5-{[(5-Fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): A Dual Orexin Receptor Antagonist with Potent Sleep-Promoting Properties
Coleman, Paul J., Schreier, John D., Cox, Christopher D., Breslin, Michael J., Whitman, David B., Bogusky, Michael J., McGaughey, Georgia B., Bednar, Rodney A., Lemaire, Wei, Doran, Scott M., Fox, Steven V., Garson, Susan L., Gotter, Anthony L., Harrell, C. Meacham, Reiss, Duane R., Cabalu, Tamara D., Cui, Donghui, Prueksaritanont, Thomayant, Stevens, Joanne, Tannenbaum, Pamela L., Ball, Richard G., Stellabott, Joyce, Young, Steven D., Hartman, George D., Winrow, Christopher J., Renger, John J.
Published in ChemMedChem (05.03.2012)
Published in ChemMedChem (05.03.2012)
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Cover Picture: Discovery of 5''-Chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2':5',3''-terpyridine-3'-carboxamide (MK-1064): A Selective Orexin2 Receptor Antagonist (2-SORA) for the Treatment of Insomnia (ChemMedChem 2/2014)
Roecker, Anthony J, Mercer, Swati P, Schreier, John D, Cox, Christopher D, Fraley, Mark E, Steen, Justin T, Lemaire, Wei, Bruno, Joseph G, Harrell, C Meacham, Garson, Susan L, Gotter, Anthony L, Fox, Steven V, Stevens, Joanne, Tannenbaum, Pamela L, Prueksaritanont, Thomayant, Cabalu, Tamara D, Cui, Donghui, Stellabott, Joyce, Hartman, George D, Young, Steven D, Winrow, Christopher J, Renger, John J, Coleman, Paul J
Published in ChemMedChem (01.02.2014)
Published in ChemMedChem (01.02.2014)
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Journal Article
Discovery of 5''-Chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2':5',3''-terpyridine-3'-carboxamide (MK-1064): A Selective Orexin2 Receptor Antagonist (2-SORA) for the Treatment of Insomnia
Roecker, Anthony J, Mercer, Swati P, Schreier, John D, Cox, Christopher D, Fraley, Mark E, Steen, Justin T, Lemaire, Wei, Bruno, Joseph G, Harrell, C Meacham, Garson, Susan L, Gotter, Anthony L, Fox, Steven V, Stevens, Joanne, Tannenbaum, Pamela L, Prueksaritanont, Thomayant, Cabalu, Tamara D, Cui, Donghui, Stellabott, Joyce, Hartman, George D, Young, Steven D, Winrow, Christopher J, Renger, John J, Coleman, Paul J
Published in ChemMedChem (01.02.2014)
Published in ChemMedChem (01.02.2014)
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Journal Article
Cover Picture: Discovery of 5′′-Chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2′:5′,3′′-terpyridine-3′-carboxamide (MK-1064): A Selective Orexin 2 Receptor Antagonist (2-SORA) for the Treatment of Insomnia (ChemMedChem 2/2014)
Roecker, Anthony J., Mercer, Swati P., Schreier, John D., Cox, Christopher D., Fraley, Mark E., Steen, Justin T., Lemaire, Wei, Bruno, Joseph G., Harrell, C. Meacham, Garson, Susan L., Gotter, Anthony L., Fox, Steven V., Stevens, Joanne, Tannenbaum, Pamela L., Prueksaritanont, Thomayant, Cabalu, Tamara D., Cui, Donghui, Stellabott, Joyce, Hartman, George D., Young, Steven D., Winrow, Christopher J., Renger, John J., Coleman, Paul J.
Published in ChemMedChem (01.02.2014)
Published in ChemMedChem (01.02.2014)
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Journal Article
Cover Picture: Discovery of [(2R,5R)-5-{[(5-Fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): A Dual Orexin Receptor Antagonist with Potent Sleep-Promoting Properties (ChemMedChem 3/2012)
Coleman, Paul J., Schreier, John D., Cox, Christopher D., Breslin, Michael J., Whitman, David B., Bogusky, Michael J., McGaughey, Georgia B., Bednar, Rodney A., Lemaire, Wei, Doran, Scott M., Fox, Steven V., Garson, Susan L., Gotter, Anthony L., Harrell, C. Meacham, Reiss, Duane R., Cabalu, Tamara D., Cui, Donghui, Prueksaritanont, Thomayant, Stevens, Joanne, Tannenbaum, Pamela L., Ball, Richard G., Stellabott, Joyce, Young, Steven D., Hartman, George D., Winrow, Christopher J., Renger, John J.
Published in ChemMedChem (05.03.2012)
Published in ChemMedChem (05.03.2012)
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Pseudopolymorphs of an HCV NS5A inhibitor and uses thereof
Sherry, Benjamin D, Liu, Yong, Cohen, Ryan, Mangion, Ian, Feng, Kung-I, McNevin, Michael, Zhang, Yanfeng, Lee, Alfred, Schultz, Scott, Stellabott, Joyce, Martin, Gary
Year of Publication 01.01.2019
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Year of Publication 01.01.2019
Patent
PSEUDOPOLYMORPHS OF AN HCV NS5A INHIBITOR AND USES THEREOF
MANGION Ian, COHEN Ryan, ZHANG Yanfeng, STELLABOTT Joyce, SHERRY Benjamin D, McNEVIN Michael, FENG Kung-I, SHULTZ Scott, LEE Alfred, LIU Yong, MARTIN Gary
Year of Publication 27.10.2016
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Year of Publication 27.10.2016
Patent
POLYMORPHS OF ANDROGEN RECEPTOR MODULATOR - (N-3H-IMIDAZO [4 , 5-B] PYRIDIN-2-YL-METHYL) -2-FLUORO-4-METHYL-3-OXO-4-AZA-ANDROST- 1-EN-17 . BETA . -CARBOXAMIDE
KIANG, YUAN-HON, COTE, AARON, S, STELLABOTT, JOYCE, MEISSNER, ROBERT S, TAN, LUSHI, PERKINS, JAMES, J, LI, WENJIE
Year of Publication 17.10.2012
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Year of Publication 17.10.2012
Patent
Polymorphs of androgen receptor modulator - (N-3H-imidazo [4 , 5-B] pyridin-2-yl-methyl) -2-fluoro-4-methyl-3-oxo-4-aza-androst- l-en-17 . beta . -carboxamide
KIANG, YUAN-HON, STELLABOTT, JOYCE, MEISSNER, ROBERT S, COTE, AARON S, TAN, LUSHI, PERKINS, JAMES J, LI, WENJIE
Year of Publication 19.01.2012
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Year of Publication 19.01.2012
Patent
Polymorphs of androgen receptor modulator N-(3H-imidazo[4,5-B]pyridin-2-ylmethyl)-2-fluoro-4-methyl-3-oxo-4-aza-5-alpha-androst-1-en-17-beta-carboxamide
KIANG, YUAN-HON, STELLABOTT, JOYCE, MEISSNER, ROBERT S, COTE, AARON S, TAN, LUSHI, PERKINS, JAMES J, LI, WENJIE
Year of Publication 30.09.2011
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Year of Publication 30.09.2011
Patent
LIQUID PHARMACEUTICAL FORMULATIONS FOR ORAL ADMINISTRATION OF A CGRP ANTAGONIST
ALANI, LAMAN, L, THOMPSON, KAREN, BRESLIN, DAVID, STELLABOTT, JOYCE, JAHANSOUZ, HOSSAIN
Year of Publication 03.06.2009
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Year of Publication 03.06.2009
Patent