Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma
Jensen, Samuel A, Day, Emily S, Ko, Caroline H, Hurley, Lisa A, Luciano, Janina P, Kouri, Fotini M, Merkel, Timothy J, Luthi, Andrea J, Patel, Pinal C, Cutler, Joshua I, Daniel, Weston L, Scott, Alexander W, Rotz, Matthew W, Meade, Thomas J, Giljohann, David A, Mirkin, Chad A, Stegh, Alexander H
Published in Science translational medicine (30.10.2013)
Published in Science translational medicine (30.10.2013)
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A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma
Kumthekar, Priya, Ko, Caroline H, Paunesku, Tatjana, Dixit, Karan, Sonabend, Adam M, Bloch, Orin, Tate, Matthew, Schwartz, Margaret, Zuckerman, Laura, Lezon, Ray, Lukas, Rimas V, Jovanovic, Borko, McCortney, Kathleen, Colman, Howard, Chen, Si, Lai, Barry, Antipova, Olga, Deng, Junjing, Li, Luxi, Tommasini-Ghelfi, Serena, Hurley, Lisa A, Unruh, Dusten, Sharma, Nitya V, Kandpal, Manoj, Kouri, Fotini M, Davuluri, Ramana V, Brat, Daniel J, Muzzio, Miguel, Glass, Mitchell, Vijayakumar, Vinod, Heidel, Jeremy, Giles, Francis J, Adams, Ann K, James, C David, Woloschak, Gayle E, Horbinski, Craig, Stegh, Alexander H
Published in Science translational medicine (10.03.2021)
Published in Science translational medicine (10.03.2021)
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miRNA-182 and the regulation of the glioblastoma phenotype - toward miRNA-based precision therapeutics
Kouri, Fotini M, Ritner, Carissa, Stegh, Alexander H
Published in Cell cycle (Georgetown, Tex.) (17.12.2015)
Published in Cell cycle (Georgetown, Tex.) (17.12.2015)
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Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies
Stommel, Jayne M, Kimmelman, Alec C, Ying, Haoqiang, Nabioullin, Roustem, Ponugoti, Aditya H, Wiedemeyer, Ruprecht, Stegh, Alexander H, Bradner, James E, Ligon, Keith L, Brennan, Cameron, Chin, Lynda, DePinho, Ronald A
Published in Science (American Association for the Advancement of Science) (12.10.2007)
Published in Science (American Association for the Advancement of Science) (12.10.2007)
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Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation
Calvert, Andrea E., Chalastanis, Alexandra, Wu, Yongfei, Hurley, Lisa A., Kouri, Fotini M., Bi, Yingtao, Kachman, Maureen, May, Jasmine L., Bartom, Elizabeth, Hua, Youjia, Mishra, Rama K., Schiltz, Gary E., Dubrovskyi, Oleksii, Mazar, Andrew P., Peter, Marcus E., Zheng, Hongwu, James, C. David, Burant, Charles F., Chandel, Navdeep S., Davuluri, Ramana V., Horbinski, Craig, Stegh, Alexander H.
Published in Cell reports (Cambridge) (30.05.2017)
Published in Cell reports (Cambridge) (30.05.2017)
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miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma
Kouri, Fotini M, Hurley, Lisa A, Daniel, Weston L, Day, Emily S, Hua, Youjia, Hao, Liangliang, Peng, Chian-Yu, Merkel, Timothy J, Queisser, Markus A, Ritner, Carissa, Zhang, Hailei, James, C David, Sznajder, Jacob I, Chin, Lynda, Giljohann, David A, Kessler, John A, Peter, Marcus E, Mirkin, Chad A, Stegh, Alexander H
Published in Genes & development (01.04.2015)
Published in Genes & development (01.04.2015)
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Internalized CD44s splice isoform attenuates EGFR degradation by targeting Rab7A
Wang, Wei, Zhang, Honghong, Liu, Sali, Kim, Chung Kwon, Xu, Yilin, Hurley, Lisa A., Nishikawa, Ryo, Nagane, Motoo, Hu, Bo, Stegh, Alexander H., Cheng, Shi-Yuan, Cheng, Chonghui
Published in Proceedings of the National Academy of Sciences - PNAS (01.08.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (01.08.2017)
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Multimodal neuro-nanotechnology: Challenging the existing paradigm in glioblastoma therapy
Kudruk, Sergej, Forsyth, Connor M, Dion, Michelle Z, Hedlund Orbeck, Jenny K, Luo, Jingqin, Klein, Robyn S, Kim, Albert H, Heimberger, Amy B, Mirkin, Chad A, Stegh, Alexander H, Artzi, Natalie
Published in Proceedings of the National Academy of Sciences - PNAS (20.02.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (20.02.2024)
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Malignant astrocytic glioma: genetics, biology, and paths to treatment
Furnari, Frank B, Fenton, Tim, Bachoo, Robert M, Mukasa, Akitake, Stommel, Jayne M, Stegh, Alexander, Hahn, William C, Ligon, Keith L, Louis, David N, Brennan, Cameron, Chin, Lynda, DePinho, Ronald A, Cavenee, Webster K
Published in Genes & development (01.11.2007)
Published in Genes & development (01.11.2007)
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Bcl2L13 is a ceramide synthase inhibitor in glioblastoma
Jensen, Samuel A., Calvert, Andrea E., Volpert, Giora, Kouri, Fotini M., Hurley, Lisa A., Luciano, Janina P., Wu, Yongfei, Chalastanis, Alexandra, Futerman, Anthony H., Stegh, Alexander H.
Published in Proceedings of the National Academy of Sciences - PNAS (15.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (15.04.2014)
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SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression
Ding, Zhihu, Wu, Chang-Jiun, Chu, Gerald C., Xiao, Yonghong, Ho, Dennis, Zhang, Jingfang, Perry, Samuel R., Labrot, Emma S., Wu, Xiaoqiu, Lis, Rosina, Hoshida, Yujin, Hiller, David, Hu, Baoli, Jiang, Shan, Zheng, Hongwu, Stegh, Alexander H., Scott, Kenneth L., Signoretti, Sabina, Bardeesy, Nabeel, Wang, Y. Alan, Hill, David E., Golub, Todd R., Stampfer, Meir J., Wong, Wing H., Loda, Massimo, Mucci, Lorelei, Chin, Lynda, DePinho, Ronald A.
Published in Nature (London) (10.02.2011)
Published in Nature (London) (10.02.2011)
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Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth
Hashizume, Rintaro, Zhang, Ali, Mueller, Sabine, Prados, Michael D, Lulla, Rishi R, Goldman, Stewart, Saratsis, Amanda M, Mazar, Andrew P, Stegh, Alexander H, Cheng, Shi-Yuan, Horbinski, Craig, Haas-Kogan, Daphne A, Sarkaria, Jann N, Waldman, Todd, James, C David
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2016)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2016)
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Ribozyme–Spherical Nucleic Acids
Rouge, Jessica L, Sita, Timothy L, Hao, Liangliang, Kouri, Fotini M, Briley, William E, Stegh, Alexander H, Mirkin, Chad A
Published in Journal of the American Chemical Society (26.08.2015)
Published in Journal of the American Chemical Society (26.08.2015)
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