Site-Specific Antibody–Drug Conjugation through Glycoengineering
Zhou, Qun, Stefano, James E, Manning, Charlene, Kyazike, Josephine, Chen, Bo, Gianolio, Diego A, Park, Anna, Busch, Michelle, Bird, Julie, Zheng, Xiaoyang, Simonds-Mannes, Helene, Kim, Jennifer, Gregory, Rick C, Miller, Robert J, Brondyk, William H, Dhal, Pradeep K, Pan, Clark Q
Published in Bioconjugate chemistry (19.03.2014)
Published in Bioconjugate chemistry (19.03.2014)
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A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms
Stefano, James E., Lord, Dana M., Zhou, Yanfeng, Jaworski, Julie, Hopke, Joern, Travaline, Tara, Zhang, Ningning, Wong, Karen, Lennon, Amanda, He, Timothy, Bric-Furlong, Eva, Cherrie, Cornishia, Magnay, Tristan, Remy, Elisabeth, Brondyk, William, Qiu, Huawei, Radošević, Katarina
Published in The Journal of biological chemistry (25.12.2020)
Published in The Journal of biological chemistry (25.12.2020)
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Convergent synthesis of hydrophilic monomethyl dolastatin 10 based drug linkers for antibody-drug conjugation
Yang, Kanwen, Chen, Bo, Gianolio, Diego A, Stefano, James E, Busch, Michelle, Manning, Charlene, Alving, Kim, Gregory, Richard C, Brondyk, William H, Miller, Robert J, Dhal, Pradeep K
Published in Organic & biomolecular chemistry (21.09.2019)
Published in Organic & biomolecular chemistry (21.09.2019)
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biAb Mediated Restoration of the Linkage between Dystroglycan and Laminin-211 as a Therapeutic Approach for α-Dystroglycanopathies
Gumlaw, Nathan, Sevigny, Leila M., Zhao, Hongmei, Luo, Zhengyu, Bangari, Dinesh S., Masterjohn, Elizabeth, Chen, Yangde, McDonald, Barbara, Magnay, Maureen, Travaline, Tara, Yoshida-Moriguchi, Takako, Fan, Wei, Reczek, David, Stefano, James E., Qiu, Huawei, Beil, Christian, Lange, Christian, Rao, Ercole, Lukason, Michael, Barry, Elizabeth, Brondyk, William H., Zhu, Yunxiang, Cheng, Seng H.
Published in Molecular therapy (05.02.2020)
Published in Molecular therapy (05.02.2020)
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Design, Synthesis, and in vitro Evaluation of Multivalent Drug Linkers for High‐Drug‐Load Antibody–Drug Conjugates
Chen, Bo, Gianolio, Diego A., Stefano, James E., Manning, Charlene M., Gregory, Richard C., Busch, Michelle M., Brondyk, William H., Miller, Robert J., Dhal, Pradeep K.
Published in ChemMedChem (23.04.2018)
Published in ChemMedChem (23.04.2018)
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Strategies for Neoglycan Conjugation to Human Acid α-Glucosidase
Zhou, Qun, Stefano, James E, Harrahy, John, Finn, Patrick, Avila, Luis, Kyazike, Josephine, Wei, Ronnie, Van Patten, Scott M, Gotschall, Russell, Zheng, Xiaoyang, Zhu, Yunxiang, Edmunds, Tim, Pan, Clark Q
Published in Bioconjugate chemistry (20.04.2011)
Published in Bioconjugate chemistry (20.04.2011)
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Carbohydrate-Mediated Polyethylene Glycol Conjugation of TSH Improves Its Pharmacological Properties
Park, Anna, Honey, Denise M, Hou, Lihui, Bird, Julie J, Zarazinski, Christine, Searles, Michelle, Braithwaite, Christian, Kingsbury, Jonathan S, Kyazike, Josephine, Culm-Merdek, Kerry, Greene, Ben, Stefano, James E, Qiu, Huawei, McPherson, John M, Pan, Clark Q
Published in Endocrinology (Philadelphia) (01.03.2013)
Published in Endocrinology (Philadelphia) (01.03.2013)
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High-Affinity VEGF Antagonists by Oligomerization of a Minimal Sequence VEGF-Binding Domain
Stefano, James E, Bird, Julie, Kyazike, Josephine, Cheng, Anthony Wai-Ming, Boudanova, Ekaterina, Dwyer, Markryan, Hou, Lihui, Qiu, Huawei, Matthews, Gloria, O’Callaghan, Michael, Pan, Clark Q
Published in Bioconjugate chemistry (19.12.2012)
Published in Bioconjugate chemistry (19.12.2012)
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Targeting HER2-positive cancer with dolastatin 15 derivatives conjugated to trastuzumab, novel antibody–drug conjugates
Gianolio, Diego A., Rouleau, Cecile, Bauta, William E., Lovett, Dennis, Cantrell, William R., Recio, Antonio, Wolstenholme-Hogg, Paul, Busch, Michelle, Pan, Peng, Stefano, James E., Kramer, Hildegard M., Goebel, James, Krumbholz, Roy D., Roth, Stephanie, Schmid, Steven M., Teicher, Beverly A.
Published in Cancer chemotherapy and pharmacology (01.09.2012)
Published in Cancer chemotherapy and pharmacology (01.09.2012)
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Micro- and mid-scale maleimide-based conjugation of cytotoxic drugs to antibody hinge region thiols for tumor targeting
Stefano, James E, Busch, Michelle, Hou, Lihui, Park, Anna, Gianolio, Diego A
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2013)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2013)
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Journal Article
Design, Synthesis, and invitro Evaluation of Multivalent Drug Linkers for High-Drug-Load Antibody-Drug Conjugates
Chen, Bo, Gianolio, Diego A., Stefano, James E., Manning, Charlene M., Gregory, Richard C., Busch, Michelle M., Brondyk, William H., Miller, Robert J., Dhal, Pradeep K.
Published in ChemMedChem (23.04.2018)
Published in ChemMedChem (23.04.2018)
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Journal Article
SITE-SPECIFIC ANTIBODY-DRUG CONJUGATION THROUGH GLYCOENGINEERING
DHAL PRADEEP, MILLER ROBERT, QIU HUAWEI, ZHOU QUN, PAN CLARK, STEFANO JAMES, CHEN BO, GIANOLIO DIEGO
Year of Publication 09.02.2023
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Year of Publication 09.02.2023
Patent
SITE-SPECIFIC ANTIBODY-DRUG CONJUGATION THROUGH GLYCOENGINEERING
DHAL PRADEEP, MILLER ROBERT, QIU HUAWEI, ZHOU QUN, PAN CLARK, STEFANO JAMES, CHEN BO, GIANOLIO DIEGO
Year of Publication 01.12.2021
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Year of Publication 01.12.2021
Patent
A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms
Stefano, James E, Lord, Dana M, Zhou, Yanfeng, Jaworski, Julie, Hopke, Joern, Travaline, Tara, Zhang, Ningning, Wong, Karen, Lennon, Amanda, He, Timothy, Bric-Furlong, Eva, Cherrie, Cornishia, Magnay, Tristan, Remy, Elisabeth, Brondyk, William, Qiu, Huawei, Radošević, Katarina
Published in The Journal of biological chemistry (25.12.2020)
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Published in The Journal of biological chemistry (25.12.2020)
Journal Article
PEPTIDE ANALOGS OF ALPHA-MELANOCYTE STIMULATING HORMONE
PERRICONE MICHAEL A, DZURIS JOHN LYLE, STEFANO JAMES E, WEEDEN TIMOTHY E, EDLING ANDREA E, PAN CLARK Q
Year of Publication 30.10.2018
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Year of Publication 30.10.2018
Patent