Discovery of pyrrolopyrimidine inhibitors of Akt
Blake, James F., Kallan, Nicholas C., Xiao, Dengming, Xu, Rui, Bencsik, Josef R., Skelton, Nicholas J., Spencer, Keith L., Mitchell, Ian S., Woessner, Richard D., Gloor, Susan L., Risom, Tyler, Gross, Stefan D., Martinson, Matthew, Morales, Tony H., Vigers, Guy P.A., Brandhuber, Barbara J.
Published in Bioorganic & medicinal chemistry letters (01.10.2010)
Published in Bioorganic & medicinal chemistry letters (01.10.2010)
Get full text
Journal Article
Discovery and SAR of spirochromane Akt inhibitors
Kallan, Nicholas C., Spencer, Keith L., Blake, James F., Xu, Rui, Heizer, Justin, Bencsik, Josef R., Mitchell, Ian S., Gloor, Susan L., Martinson, Matthew, Risom, Tyler, Gross, Stefan D., Morales, Tony H., Wu, Wen-I, Vigers, Guy P.A., Brandhuber, Barbara J., Skelton, Nicholas J.
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
Get full text
Journal Article
Pharmacological effects of small molecule BCR-ABL tyrosine kinase inhibitors on platelet function
Zhang, Yiheng, Yang, Chih-Jen, Melrose, Alexander R, Pang, Jiaqing, Schofield, Kirrali, Song, Serena D, Parra-Izquierdo, Iván, Zheng, Tony J, Lyssikatos, Joseph P, Gross, Stefan D, Shatzel, Joseph J, McCarty, Owen J T, Aslan, Joseph E
Published in The Journal of pharmacology and experimental therapeutics (08.10.2024)
Published in The Journal of pharmacology and experimental therapeutics (08.10.2024)
Get full text
Journal Article
The mechanism of CSF arrest in vertebrate oocytes
Maller, James L, Schwab, Markus S, Gross, Stefan D, Taieb, Frédéric E, Roberts, B.Tibor, Tunquist, Brian J
Published in Molecular and cellular endocrinology (22.02.2002)
Published in Molecular and cellular endocrinology (22.02.2002)
Get full text
Journal Article
Discovery of spirocyclic sulfonamides as potent Akt inhibitors with exquisite selectivity against PKA
Xu, Rui, Banka, Anna, Blake, James F., Mitchell, Ian S., Wallace, Eli M., Bencsik, Josef R., Kallan, Nicholas C., Spencer, Keith L., Gloor, Susan L., Martinson, Matthew, Risom, Tyler, Gross, Stefan D., Morales, Tony H., Wu, Wen-I, Vigers, Guy P.A., Brandhuber, Barbara J., Skelton, Nicholas J.
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
Get full text
Journal Article
Elvn-001, a Next Generation ATP-Competitive ABL1 Tyrosine Kinase Inhibitor for the Treatment of Chronic Myeloid Leukemia
Gross, Stefan D, Eide, Christopher A., Burkard, Michael R, Reister Schultz, Anna, Aujay, Monette A, Kintz, Samuel, Druker, Brian J., Lyssikatos, Joseph P
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
Get full text
Journal Article
The pathway of MAP kinase mediation of CSF arrest in Xenopus oocytes
Maller, James L., Schwab, Markus S., Roberts, B.Tibor, Gross, Stefan D., Taieb, Frédéric E., Tunquist, Brian J.
Published in Biology of the Cell (01.09.2001)
Published in Biology of the Cell (01.09.2001)
Get full text
Book Review
Journal Article
Bub1 is activated by the protein kinase p90 Rsk during Xenopus oocyte maturation
Schwab, Markus S, Roberts, B.Tibor, Gross, Stefan D, Tunquist, Brian J, Taieb, Frédéric E, Lewellyn, Andrea L, Maller, James L
Published in Current biology (01.02.2001)
Published in Current biology (01.02.2001)
Get full text
Journal Article
Abstract 4019: Preclinical activity of ELVN-002: A potent, selective, and irreversible HER2 and pan-HER2 mutant small molecule inhibitor for the treatment of HER2 driven malignancies
Aujay, Monette, Broad, Amanda J., Gross, Stefan D., Ren, Li, Lyssikatos, Joseph P., Kintz, Samuel, Wang, Qi, Collins, Helen
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Get full text
Journal Article
The critical role of the MAP kinase pathway in meiosis II in Xenopus oocytes is mediated by p90(Rsk)
Gross, S D, Schwab, M S, Taieb, F E, Lewellyn, A L, Qian, Y W, Maller, J L
Published in Current biology (20.04.2000)
Published in Current biology (20.04.2000)
Get full text
Journal Article
Abstract 551: A potent and selective cFMS inhibitor regulates the tumor macrophage microenvironment leading to tumor growth inhibition
Wright, Albion D., Willis, Brandon S., Gomez, Anna, Boys, Mark L., DeLisle, Robert K., Burgess, Laurence E., Munson, Mark C., Kennedy, April L., Topalov, George T., Zhao, Qian, Rodriguez, Martha E., Rast, Bryson, Rizzi, James P., DeWolf, Walter E., Lemieux, Christine, Anderson, Deborah, Neale, Jason R., Martinson, Matthew, Gross, Stefan D., Callejo, Michele, Risom, Tyler, Lee, Patrice A.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Get full text
Journal Article
Abstract B267: AR-mTOR-1: A potent, selective mTORC 1/2 kinase inhibitor for the treatment of malignancy
Wallace, Eli M., Xu, Rui, Josey, John, Gross, Stefan D., DeMeese, Lisa, Fischer, John, Miknis, Greg, Humphries, Mike, Regal, Kelly, Fell, Brad, Burkard, Michael, DeWolf, Walt E., Gloor, Susan, Hastings, Gregg, Zuzack, John, Winkler, James, Koch, Kevin
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
Get full text
Journal Article
Abstract 4484: AR-mTOR-26 - A potent, selective mTORC 1/2 kinase inhibitor for the treatment of malignancy
Gross, Stefan D., Xu, Rui, Boys, Mark, Condroski, Kevin, DeMeese, Lisa, DeWolf, Walt E., Fell, Brad, Fischer, John, Gloor, Susan, Humphries, Michael J., Miknis, Greg, Regal, Kelly, Rodriguez, Mareli, Raddatz, Nicholas, Shotts, Kristin, Topalov, Georg, Wallace, Eli, Zuzack, John, Josey, John A., Winkler, James, Koch, Kevin
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Get full text
Journal Article