Roles of the Ras Raf MEK ERK pathway in leukemia therapy
Steelman, L S, Franklin, R A, Abrams, S L, Chappell, W, Kempf, C R, Bäsecke, J, Stivala, F, Donia, M, Fagone, P, Nicoletti, F, Libra, M, Ruvolo, P, Ruvolo, V, Evangelisti, C, Martelli, A M, McCubrey, J A
Published in Leukemia (01.07.2011)
Published in Leukemia (01.07.2011)
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Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K PTEN Akt mTOR pathway
Martelli, A M, Evangelisti, C, Chappell, W, Abrams, S L, Bäsecke, J, Stivala, F, Donia, M, Fagone, P, Nicoletti, F, Libra, M, Ruvolo, V, Ruvolo, P, Kempf, C R, Steelman, L S, McCubrey, J A
Published in Leukemia (01.07.2011)
Published in Leukemia (01.07.2011)
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Signal transduction mediated by the Ras Raf MEK ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention
CHANG, F, STEELMAN, L. S, LEE, J. T, SHELTON, J. G, NAVOLANIC, P. M, BLALOCK, W. L, FRANKLIN, R. A, MCCUBREY, J. A
Published in Leukemia (01.07.2003)
Published in Leukemia (01.07.2003)
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Targeting the leukemic stem cell: the Holy Grail of leukemia therapy
Misaghian, N, Ligresti, G, Steelman, L S, Bertrand, F E, Bäsecke, J, Libra, M, Nicoletti, F, Stivala, F, Milella, M, Tafuri, A, Cervello, M, Martelli, A M, McCubrey, J A
Published in Leukemia (01.01.2009)
Published in Leukemia (01.01.2009)
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JAK STAT, Raf MEK ERK, PI3K Akt and BCR-ABL in cell cycle progression and leukemogenesis
STEELMAN, L. S, POHNERT, S. C, SHELTON, J. G, FRANKLIN, R. A, BERTRAND, F. E, MCCUBREY, J. A
Published in Leukemia (01.02.2004)
Published in Leukemia (01.02.2004)
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Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention
McCubrey, J A, Steelman, L S, Bertrand, F E, Davis, N M, Abrams, S L, Montalto, G, D'Assoro, A B, Libra, M, Nicoletti, F, Maestro, R, Basecke, J, Cocco, L, Cervello, M, Martelli, A M
Published in Leukemia (01.01.2014)
Published in Leukemia (01.01.2014)
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Involvement of PI3K Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy
Chang, F, Lee, J T, Navolanic, P M, Steelman, L S, Shelton, J G, Blalock, W L, Franklin, R A, McCubrey, J A
Published in Leukemia (01.03.2003)
Published in Leukemia (01.03.2003)
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Contributions of the Raf MEK ERK, PI3K PTEN Akt mTOR and Jak STAT pathways to leukemia
Steelman, L S, Abrams, S L, Whelan, J, Bertrand, F E, Ludwig, D E, Bäsecke, J, Libra, M, Stivala, F, Milella, M, Tafuri, A, Lunghi, P, Bonati, A, Martelli, A M, McCubrey, J A
Published in Leukemia (01.04.2008)
Published in Leukemia (01.04.2008)
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The Archer and the Shield-Bearing Warrior
Loendorf, Lawrence L., Steelman, Karen L., Castañeda, Amanda M.
Published in American antiquity (01.04.2023)
Published in American antiquity (01.04.2023)
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Journal Article
Targeting survival cascades induced by activation of Ras Raf MEK ERK, PI3K PTEN Akt mTOR and Jak STAT pathways for effective leukemia therapy
McCubrey, J A, Steelman, L S, Abrams, S L, Bertrand, F E, Ludwig, D E, Bäsecke, J, Libra, M, Stivala, F, Milella, M, Tafuri, A, Lunghi, P, Bonati, A, Martelli, A M
Published in Leukemia (01.04.2008)
Published in Leukemia (01.04.2008)
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Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors
Steelman, L S, Navolanic, P M, Sokolosky, M L, Taylor, J R, Lehmann, B D, Chappell, W H, Abrams, S L, Wong, E W T, Stadelman, K M, Terrian, D M, Leslie, N R, Martelli, A M, Stivala, F, Libra, M, Franklin, R A, McCubrey, J A
Published in Oncogene (03.07.2008)
Published in Oncogene (03.07.2008)
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Involvement of p53 and Raf MEK ERK pathways in hematopoietic drug resistance
McCubrey, J A, Abrams, S L, Ligresti, G, Misaghian, N, Wong, E W T, Steelman, L S, Bäsecke, J, Troppmair, J, Libra, M, Nicoletti, F, Molton, S, McMahon, M, Evangelisti, C, Martelli, A M
Published in Leukemia (01.11.2008)
Published in Leukemia (01.11.2008)
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Synergy between an IGF-1R antibody and Raf MEK ERK and PI3K Akt mTOR pathway inhibitors in suppressing IGF-1R-mediated growth in hematopoietic cells
BERTRAND, F. E, STEELMAN, L. S, CHAPPELL, W. H, ABRAMS, S. L, SHELTON, J. G, WHITE, E. R, LUDWIG, D. L, MCCUBREY, J. A
Published in Leukemia (01.07.2006)
Published in Leukemia (01.07.2006)
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A Phase I dose-escalation study of the VEGFR inhibitor tivozanib hydrochloride with weekly paclitaxel in metastatic breast cancer
Mayer, Erica L., Scheulen, M. E., Beckman, J., Richly, H., Duarte, A., Cotreau, M. M., Strahs, A. L., Agarwal, S., Steelman, L., Winer, E. P., Dickler, M. N.
Published in Breast cancer research and treatment (01.07.2013)
Published in Breast cancer research and treatment (01.07.2013)
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Application of supercritical carbon dioxide–co-solvent mixtures for removal of organic material from archeological artifacts for radiocarbon dating
Rowe, Marvin W., Phomakay, Jenny, Lay, Jackson O., Guevara, Oscar, Srinivas, Keerthi, Hollis, W. Kirk, Steelman, Karen L., Guilderson, Thomas, Stafford, Thomas W., Chapman, Sarah L., King, Jerry W.
Published in The Journal of supercritical fluids (01.07.2013)
Published in The Journal of supercritical fluids (01.07.2013)
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Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia
CARTER, B. Z, MILELLA, M, TSAO, T, MCQUEEN, T, SCHOBER, W. D, HU, W, DEAN, N. M, STEELMAN, L, MCCUBREY, J. A, ANDREEFF, M
Published in Leukemia (01.11.2003)
Published in Leukemia (01.11.2003)
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Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells : possible sites for intervention with anti-neoplastic drugs
BLALOCK, W. L, WEINSTEIN-OPPENHEIMER, C, CHANG, F, HOYLE, P. E, WANG, X.-Y, ALGATE, P. A, FRANKLIN, R. A, OBERHAUS, S. M, STEELMAN, L. S, MCCUBREY, J. A
Published in Leukemia (01.08.1999)
Published in Leukemia (01.08.1999)
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Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells
MCCUBREY, J. A, STEELMAN, L. S, HOYLE, P. E, BLALOCK, W. L, WEINSTEIN-OPPENHEIMER, C, FRANKLIN, R. A, CHERWINSKI, H, BOSCH, E, MCMAHON, M
Published in Leukemia (01.12.1998)
Published in Leukemia (01.12.1998)
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Requirement for the PI3K Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia
BLALOCK, W. L, NAVOLANIC, P. M, MCCUBREY, J. A, STEELMAN, L. S, SHELTON, J. G, MOYE, P. W, LEE, J. T, FRANKLIN, R. A, MIRZA, A, MCMAHON, M, WHITEN, M. K
Published in Leukemia (01.06.2003)
Published in Leukemia (01.06.2003)
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