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Novel tricyclic antagonists of the prostaglandin D2 receptor DP2 with efficacy in a murine model of allergic rhinitis
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Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase
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Published in MedChemComm (2017)
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Discovery and optimization of a biphenylacetic acid series of prostaglandin D₂ receptor DP2 antagonists with efficacy in a murine model of allergic rhinitis
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DP2 (CRTh2) Antagonism Reduces Ocular Inflammation Induced by Allergen Challenge and Respiratory Syncytial Virus
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Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives: high-affinity ligands to the α2δ subunit of voltage gated calcium channels
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Published in Bioorganic & medicinal chemistry letters (08.03.2004)
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Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]-pyridazine derivatives as high-affinity ligands of the α2δ subunit of voltage-gated calcium channels
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Published in Angewandte Chemie International Edition (03.01.2000)
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Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyraseThe authors declare no competing interests.The authors declare no competing financial interest.Electronic supplementary information (ESI) available: Tables, figures, bacterial strain information and compound purity data. See DOI: 10.1039/c7md00012j
Hurley, Katherine A, Santos, Thiago M. A, Fensterwald, Molly R, Rajendran, Madhusudan, Moore, Jared T, Balmond, Edward I, Blahnik, Brice J, Faulkner, Katherine C, Foss, Marie H, Heinrich, Victoria A, Lammers, Matthew G, Moore, Lucas C, Reynolds, Gregory D, Shearn-Nance, Galen P, Stearns, Brian A, Yao, Zi W, Shaw, Jared T, Weibel, Douglas B
Year of Publication 24.05.2017
Year of Publication 24.05.2017
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Journal Article
Enantioselective Construction of Vicinal Stereogenic Quaternary Centers by Dialkylation: Practical Total Syntheses of (+)- and meso-Chimonanthine
Overman, Larry E., Larrow, Jay F., Stearns, Brian A., Vance, Jennifer M.
Published in Angewandte Chemie (International ed.) (03.01.2000)
Published in Angewandte Chemie (International ed.) (03.01.2000)
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Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase† †The authors declare no competing interests. ‡ ‡The authors declare no competing financial interest. § §Electronic supplementary information (ESI) available: Tables, figures, bacterial strain information and compound purity data. See DOI: 10.1039/c7md00012j
Hurley, Katherine A., Santos, Thiago M. A., Fensterwald, Molly R., Rajendran, Madhusudan, Moore, Jared T., Balmond, Edward I., Blahnik, Brice J., Faulkner, Katherine C., Foss, Marie H., Heinrich, Victoria A., Lammers, Matthew G., Moore, Lucas C., Reynolds, Gregory D., Shearn-Nance, Galen P., Stearns, Brian A., Yao, Zi W., Shaw, Jared T., Weibel, Douglas B.
Published in MedChemComm (27.02.2017)
Published in MedChemComm (27.02.2017)
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Discovery and optimization of a biphenylacetic acid series of prostaglandin D 2 receptor DP2 antagonists with efficacy in a murine model of allergic rhinitis
Scott, Jill M., Baccei, Christopher, Bain, Gretchen, Broadhead, Alex, Evans, Jilly F., Fagan, Patrick, Hutchinson, John H., King, Christopher, Lorrain, Daniel S., Lee, Catherine, Prasit, Peppi, Prodanovich, Pat, Santini, Angelina, Stearns, Brian A.
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
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