A new antibiotic kills pathogens without detectable resistance
Ling, Losee L., Schneider, Tanja, Peoples, Aaron J., Spoering, Amy L., Engels, Ina, Conlon, Brian P., Mueller, Anna, Schäberle, Till F., Hughes, Dallas E., Epstein, Slava, Jones, Michael, Lazarides, Linos, Steadman, Victoria A., Cohen, Douglas R., Felix, Cintia R., Fetterman, K. Ashley, Millett, William P., Nitti, Anthony G., Zullo, Ashley M., Chen, Chao, Lewis, Kim
Published in Nature (London) (22.01.2015)
Published in Nature (London) (22.01.2015)
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Journal Article
Unprecedented Epimerization of an Azithromycin Analogue: Synthesis, Structure and Biological Activity of 2'-Dehydroxy-5″-Epi-Azithromycin
Kragol, Goran, Steadman, Victoria A, Marušić Ištuk, Zorica, Čikoš, Ana, Bosnar, Martina, Jelić, Dubravko, Ergović, Gabrijela, Trzun, Marija, Bošnjak, Berislav, Bokulić, Ana, Padovan, Jasna, Glojnarić, Ines, Eraković Haber, Vesna
Published in Molecules (Basel, Switzerland) (03.02.2022)
Published in Molecules (Basel, Switzerland) (03.02.2022)
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Journal Article
Structure and reactivity of bicyclic methylene aziridines prepared by intramolecular aziridination of allenes
Robertson, Jeremy, Feast, George C., White, Louise V., Steadman (nee Doughty), Victoria A., Claridge, Timothy D. W.
Published in Organic & biomolecular chemistry (28.06.2010)
Published in Organic & biomolecular chemistry (28.06.2010)
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Bifunctional crosslinking ligands for transthyretin
Mangione, P. Patrizia, Deroo, Stéphanie, Ellmerich, Stephan, Bellotti, Vittorio, Kolstoe, Simon, Wood, Stephen P., Robinson, Carol V., Smith, Martin D., Tennent, Glenys A., Broadbridge, Robert J., Council, Claire E., Thurston, Joanne R., Steadman, Victoria A., Vong, Antonio K., Swain, Christopher J., Pepys, Mark B., Taylor, Graham W.
Published in Open biology (01.09.2015)
Published in Open biology (01.09.2015)
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Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle
Mackman, Richard L, Steadman, Victoria A, Dean, David K, Jansa, Petr, Poullennec, Karine G, Appleby, Todd, Austin, Carol, Blakemore, Caroline A, Cai, Ruby, Cannizzaro, Carina, Chin, Gregory, Chiva, Jean-Yves C, Dunbar, Neil A, Fliri, Hans, Highton, Adrian J, Hui, Hon, Ji, Mingzhe, Jin, Haolun, Karki, Kapil, Keats, Andrew J, Lazarides, Linos, Lee, Yu-Jen, Liclican, Albert, Mish, Michael, Murray, Bernard, Pettit, Simon B, Pyun, Peter, Sangi, Michael, Santos, Rex, Sanvoisin, Jonathan, Schmitz, Uli, Schrier, Adam, Siegel, Dustin, Sperandio, David, Stepan, George, Tian, Yang, Watt, Gregory M, Yang, Hai, Schultz, Brian E
Published in Journal of medicinal chemistry (08.11.2018)
Published in Journal of medicinal chemistry (08.11.2018)
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Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A
Steadman, Victoria A, Pettit, Simon B, Poullennec, Karine G, Lazarides, Linos, Keats, Andrew J, Dean, David K, Stanway, Steven J, Austin, Carol A, Sanvoisin, Jonathan A, Watt, Gregory M, Fliri, Hans G, Liclican, Albert C, Jin, Debi, Wong, Melanie H, Leavitt, Stephanie A, Lee, Yu-Jen, Tian, Yang, Frey, Christian R, Appleby, Todd C, Schmitz, Uli, Jansa, Petr, Mackman, Richard L, Schultz, Brian E
Published in Journal of medicinal chemistry (09.02.2017)
Published in Journal of medicinal chemistry (09.02.2017)
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Journal Article
Erratum: A new antibiotic kills pathogens without detectable resistance
Ling, Losee L., Schneider, Tanja, Peoples, Aaron J., Spoering, Amy L., Engels, Ina, Conlon, Brian P., Mueller, Anna, Schäberle, Till F., Hughes, Dallas E., Epstein, Slava, Jones, Michael, Lazarides, Linos, Steadman, Victoria A., Cohen, Douglas R., Felix, Cintia R., Fetterman, K. Ashley, Millett, William P., Nitti, Anthony G., Zullo, Ashley M., Chen, Chao, Lewis, Kim
Published in Nature (London) (16.04.2015)
Published in Nature (London) (16.04.2015)
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Journal Article
MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES
SANVOISIN JONATHAN, WATT GREGORY M, FLIRI HANS G, LAZARIDES LINOS, KEATS ANDREW J, MACKMAN RICHARD L, APPLEBY TODD, PETTIT SIMON N, STEADMAN VICTORIA A, POULLENNEC KARINE G
Year of Publication 13.03.2014
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Year of Publication 13.03.2014
Patent
Structure and reactivity of bicyclic methylene aziridines prepared by intramolecular aziridination of allenesElectronic supplementary information (ESI) available: Selected experimental procedures, characterization data, and copies of 1H and 13C NMR spectra. CCDC reference numbers 767254 and 767255. For crystallographic data in CIF or other electronic format see DOI: 10.1039/c003693e
Robertson, Jeremy, Feast, George C, White, Louise V, Steadman (née Doughty), Victoria A, Claridge, Timothy D. W
Year of Publication 16.06.2010
Year of Publication 16.06.2010
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Journal Article
Macrocyclic inhibitors of Flaviviridae viruses
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Year of Publication 15.12.2016
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Year of Publication 15.12.2016
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inibidores macrocíclicos do vírus flaviviridae
ANDREW J. KEATS, GREGORY M. WATT, JONATHAN SANVOISIN, LINOS LAZARIDES, HANS G. FLIRI, RICHARD L. MACKMAN, KARINE G. POULLENNEC, TODD APPLEBY, VICTORIA A. STEADMAN, SIMON N. PETTIT
Year of Publication 13.09.2016
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Year of Publication 13.09.2016
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MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES
SANVOISIN, JONATHAN, LAZARIDES, LINOS, POULLENNEC, KARINE G, STEADMAN, VICTORIA A, APPLEBY, TODD, PETTIT, SIMON N, WATT, GREGORY M, FLIRI, HANS G, MACKMAN, RICHARD L, KEATS, ANDREW J
Year of Publication 31.08.2015
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Year of Publication 31.08.2015
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MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES
SANVOISIN JONATHAN, WATT GREGORY M, FLIRI HANS G, LAZARIDES LINOS, KEATS ANDREW J, MACKMAN RICHARD L, APPLEBY TODD, PETTIT SIMON N, STEADMAN VICTORIA A, POULLENNEC KARINE G
Year of Publication 31.07.2015
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Year of Publication 31.07.2015
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Macrocyclic inhibitors of flaviviridae viruses
SANVOISIN JONATHAN, WATT GREGORY M, FLIRI HANS G, LAZARIDES LINOS, KEATS ANDREW J, MACKMAN RICHARD L, APPLEBY TODD, PETTIT SIMON N, STEADMAN VICTORIA A, POULLENNEC KARINE G
Year of Publication 31.07.2015
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Year of Publication 31.07.2015
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MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES
ANDREW J. KEATS, JONATHAN SANVOISIN, GREGORY M. WATT, LINOS LAZARIDES, HANS G. FLIRI, RICHARD L. MACKMAN, KARINE G. POULLENNEC, TODD APPLEBY, VICTORIA A. STEADMAN, SIMON N. PETTIT
Year of Publication 02.06.2015
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Year of Publication 02.06.2015
Patent
Macrocyclic inhibitors of flaviviridae viruses
SANVOISIN JONATHAN, WATT GREGORY M, FLIRI HANS G, LAZARIDES LINOS, KEATS ANDREW J, MACKMAN RICHARD L, APPLEBY TODD, PETTIT SIMON N, STEADMAN VICTORIA A, POULLENNEC KARINE G
Year of Publication 13.01.2015
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Year of Publication 13.01.2015
Patent
MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES
ANDREW J. KEATS, JONATHAN SANVOISIN, GREGORY M. WATT, LINOS LAZARIDES, HANS G. FLIRI, RICHARD L. MACKMAN, KARINE G. POULLENNEC, TODD APPLEBY, VICTORIA A. STEADMAN, SIMON N. PETTIT
Year of Publication 18.07.2014
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Year of Publication 18.07.2014
Patent