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Genta, Sofia, Lajkosz, Katherine, Yee, Noelle R, Spiliopoulou, Pavlina, Heirali, Alya, Hansen, Aaron R, Siu, Lillian L, Saibil, Sam, Stayner, Lee-Anne, Yanekina, Maryia, Sauder, Maxwell B, Keshavarzi, Sareh, Salawu, Abdulazeez, Vornicova, Olga, Butler, Marcus O, Bedard, Philippe L, Razak, Albiruni R. Abdul, Rottapel, Robert, Chruscinski, Andrzej, Coburn, Bryan, Spreafico, Anna
Published in Journal of experimental & clinical cancer research (21.10.2023)
Published in Journal of experimental & clinical cancer research (21.10.2023)
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Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction
Voon, Pei Jye, Chen, Eric X, Chen, Helen X, Lockhart, Albert C, Sahebjam, Solmaz, Kelly, Karen, Vaishampayan, Ulka N, Subbiah, Vivek, Razak, Albiruni R, Renouf, Daniel J, Hotte, Sebastien J, Singh, Arti, Bedard, Philippe L, Hansen, Aaron R, Ivy, S Percy, Wang, Lisa, Stayner, Lee-Anne, Siu, Lillian L, Spreafico, Anna
Published in Journal of experimental & clinical cancer research (07.02.2022)
Published in Journal of experimental & clinical cancer research (07.02.2022)
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First-in-Class, First-in-Human Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Patients With Advanced Solid Tumors
Abdul Razak, Albiruni R, Mau-Soerensen, Morten, Gabrail, Nashat Y, Gerecitano, John F, Shields, Anthony F, Unger, Thaddeus J, Saint-Martin, Jean R, Carlson, Robert, Landesman, Yosef, McCauley, Dilara, Rashal, Tami, Lassen, Ulrik, Kim, Richard, Stayner, Lee-Anne, Mirza, Mansoor R, Kauffman, Michael, Shacham, Sharon, Mahipal, Amit
Published in Journal of clinical oncology (01.12.2016)
Published in Journal of clinical oncology (01.12.2016)
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Safety, immunologic and clinical activity of Durvalumab in combination with Olaparib or Cediranib in advanced leiomyosarcoma: Results of the DAPPER clinical trial
Salawu, Abdulazeez, Wang, Ben X, Han, Ming, Geady, Caryn, Heirali, Alya, Berman, Hal K, Pfister, Thomas D, Hernando-Calvo, Alberto, Al-Ezzi, Esmail Mutahar, Stayner, Lee-Anne, Gupta, Abha A, Ayodele, Olubukola, Lam, Bernard, Hansen, Aaron R, Spreafico, Anna, Bedard, Philippe L, Butler, Marcus O, Avery, Lisa, Coburn, Bryan, Haibe-Kains, Benjamin, Siu, Lillian L, Abdul Razak, Albiruni R
Published in Clinical cancer research (13.10.2023)
Published in Clinical cancer research (13.10.2023)
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A final report of a phase I study of veliparib (ABT-888) in combination with low-dose fractionated whole abdominal radiation therapy (LDFWAR) in patients with advanced solid malignancies and peritoneal carcinomatosis with a dose escalation in ovarian and fallopian tube cancers
Reiss, Kim A, Herman, Joseph M, Armstrong, Deborah, Zahurak, Marianna, Fyles, Anthony, Brade, Anthony, Milosevic, Michael, Dawson, Laura A, Scardina, Angela, Fischer, Patricia, Hacker-Prietz, Amy, Kinders, Robert J, Wang, Lihua, Chen, Alice, Temkin, Sarah, Horiba, Naomi, Stayner, Lee-Anne, Siu, Lillian L, Azad, Nilofer S
Published in Gynecologic oncology (01.03.2017)
Published in Gynecologic oncology (01.03.2017)
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Phase I Study of Decitabine in Combination with Vorinostat in Patients with Advanced Solid Tumors and Non-Hodgkin's Lymphomas
STATHIS, Anastasios, HOTTE, Sebastien J, WANG, Lisa, ZHANG, Wen-Jiang, ESPINOZA-DELGADO, Igor, HOLLERAN, Julianne L, EGORIN, Merrill J, SIU, Lillian L, CHEN, Eric X, HIRTE, Holger W, OZA, Amit M, MORETTO, Patricia, WEBSTER, Sheila, LAUGHLIN, Anne, STAYNER, Lee-Anne, MCGILL, Shauna
Published in Clinical cancer research (15.03.2011)
Published in Clinical cancer research (15.03.2011)
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A phase II trial of GSK2256098 and trametinib in patients with advanced pancreatic ductal adenocarcinoma
Aung, Kyaw L, McWhirter, Elaine, Welch, Stephen, Wang, Lisa, Lovell, Sophia, Stayner, Lee-Anne, Ali, Saara, Malpage, Anne, Makepeace, Barbara, Ramachandran, Makilpriya, Jang, Gun Ho, Gallinger, Steven, Zhang, Tong, Stockley, Tracy L, Fischer, Sandra E, Dhani, Neesha, Hedley, David, Knox, Jennifer J, Siu, Lillian L, Goodwin, Rachel, Bedard, Philippe L
Published in Journal of gastrointestinal oncology (01.12.2022)
Published in Journal of gastrointestinal oncology (01.12.2022)
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A phase I trial of two sequence-specific schedules of decitabine and vorinostat in patients with acute myeloid leukemia
How, Jonathan, Minden, Mark D, Brian, Leber, Chen, Eric X, Brandwein, Joseph, Schuh, Andre C, Schimmer, Aaron D, Gupta, Vikas, Webster, Sheila, Degelder, Tammy, Haines, Patricia, Stayner, Lee-Anne, McGill, Shauna, Wang, Lisa, Piekarz, Richard, Wong, Tracy, Siu, Lillian L, Espinoza-Delgado, Igor, Holleran, Julianne L, Egorin, Merrill J, Yee, Karen W L
Published in Leukemia & lymphoma (03.10.2015)
Published in Leukemia & lymphoma (03.10.2015)
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Abstract P1-18-17: Phase I study of cfi-402257, an oral ttk inhibitor, in patients with advanced solid tumors with breast cancer expansion cohorts
Hilton, John, Renouf, Daniel J, Cescon, David W, Hansen, Aaron R, Razak, Albiruni RA, Stayner, Lee-Anne, Denny, Trisha, Fletcher, Graham, Mak, Tak W, Bray, Mark, Bedard, Philippe L
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Immune correlates of outcome in patients with leiomyosarcoma (LMS) treated with durvalumab plus olaparib or cediranib: Transcriptome analysis from the DAPPER study
Salawu, Abdulazeez, Han, Ming, Gupta, Abha A., Berman, Hal, Wang, Ben X, Pfister, Thomas D, Hernando-Calvo, Alberto, Al-Ezzi, Esmail Mutahar, Ayodele, Olubukola, Stayner, Lee-Anne, Lam, Bernard, Hansen, Aaron Richard, Spreafico, Anna, Bedard, Philippe L., Butler, Marcus O., Haibe-Kains, Benjamin, Avery, Lisa, Siu, Lillian L., Abdul Razak, Albiruni Ryan
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Customized autoantibodies (autoAbs) profiling to predict and monitor immune-related adverse events (irAEs) in patients receiving immune checkpoint inhibitors (ICI)
Genta, Sofia, Keshavarzi, Sareh, Yee, Noelle, Heirali, Alya, Hansen, Aaron Richard, Siu, Lillian L., Saibil, Samuel, Stayner, Lee-Anne, Yanekina, Maryia, Sauder, Maxwell, Salawu, Abdulazeez, Spiliopoulou, Pavlina, Vornicova, Olga, Vilbert, Maysa Tamara Silveira, Butler, Marcus O., Bedard, Philippe L., Abdul Razak, Albiruni Ryan, Coburn, Bryan, Chruscinski, Andrzej, Spreafico, Anna
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Abstract P035: A phase 1 pharmacokinetic trial of single agent trametinib a MEK inhibitor in advanced cancer patients with hepatic dysfunction: An NCI Organ Dysfunction Working Group (ODWG) study (NCI 9591)
Voon, Pei Jye, Chen, Eric X., Chen, Helen X., Lockhart, Albert C., Sahebjam, Solmaz, Kelly, Karen, Vaishampayan, Ulka N., Subbiah, Vivek, Razak, Albiruni R., Renouf, Daniel J., Hotte, Sebastien J., Singh, Arti, Bedard, Philippe L., Hansen, Aaron R., Percy, Ivy S., Wang, Lisa, Stayner, Lee-Anne, Siu, Lillian L., Spreafico, Anna
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
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First-in-class microbial ecosystem therapeutics 4 (MET4) in metastatic solid cancer patients treated with immunotherapy: MET4-IO
Araujo, Daniel Vilarim, Oliva Bernal, Marc, Tan, Tira Jing Ying, Heirali, Alya Abbas, Schneeberger, Pierre H.H., Pimentel Muniz, Thiago, Chen, Bo, Stayner, Lee-Anne, Xia, Kathy, Hansen, Aaron Richard, Wang, Ben X, Hogg, David, Cochrane, Kyla, Langer, Shawn, Mashiach, Nissim, Xu, Wei, Siu, Lillian L., Coburn, Bryan, Spreafico, Anna
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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A Phase II, Open-Label, Randomized Trial of Durvalumab With Olaparib or Cediranib in Patients With Mismatch Repair—Proficient Colorectal or Pancreatic Cancer
Hernando-Calvo, Alberto, Han, Ming, Ayodele, Olubukola, Wang, Ben X., Bruce, Jeffrey P., Abbas-Aghababazadeh, Farnoosh, Vila-Casadesús, Maria, Sanz-Garcia, Enrique, Yang, S.Y. Cindy, Berman, Hal K., Vivancos, Ana, Lam, Bernard, Lungu, Ilinca, Salawu, Abdulazeez, Stayner, Lee-Anne, Haibe-Kains, Benjamin, Bedard, Philippe L., Avery, Lisa, Razak, Albiruni R.A., Pugh, Trevor J., Spreafico, Anna, Siu, Lillian L., Hansen, Aaron R.
Published in Clinical colorectal cancer (01.09.2024)
Published in Clinical colorectal cancer (01.09.2024)
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Abstract P6-10-13: An update to a Phase I trial of CFI-402257, an oral TTK inhibitor, in patients with advanced solid tumors with HER2-negative breast cancer expansion cohorts
Hilton, John, Renouf, Daniel, Cescon, David W., Hansen, Aaron, Razak, Alibiruni Abdul, Stayner, Lee-Anne, Denny, Trisha A., Roberts-Thomson, Emily, Chen, Dih-Yih, Bray, Mark, Bedard, Philippe
Published in Cancer research (Chicago, Ill.) (01.03.2023)
Published in Cancer research (Chicago, Ill.) (01.03.2023)
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A phase II trial of GSK2256098 and trametinib in patients with advanced pancreatic ductal adenocarcinoma (PDAC) (MOBILITY-002 Trial, NCT02428270)
Aung, Kyaw Lwin, McWhirter, Elaine, Welch, Stephen, Wang, Lisa, Lovell, Sophia, Stayner, Lee-Anne, Ali, Saara, Malpage, Anne, Makepeace, Barbara, Ramachandran, Makilpriya, Dhani, Neesha C., Hedley, David W., Knox, Jennifer J., Siu, Lillian L., Goodwin, Rachel Anne, Bedard, Philippe L.
Published in Journal of clinical oncology (01.02.2018)
Published in Journal of clinical oncology (01.02.2018)
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Phase I study of CFI-402257, an oral TTK inhibitor, in patients with advanced solid tumors
Cescon, David W., Hansen, Aaron Richard, Abdul Razak, Albiruni Ryan, Stayner, Lee-Anne, Hilton, John Frederick, Renouf, Daniel John, Denny, Trisha, Fletcher, Graham, Mak, Tak W, Bray, Mark R, Bedard, Philippe L
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Deciphering the tumor microenvironment (TME) dynamics in advanced colorectal (CRC) and pancreatic cancers (PDAC) treated with durvalumab (D) with olaparib (O) or cediranib (C): Results from a phase 2 randomized trial
Hernando-Calvo, Alberto, Han, Ming, Ayodele, Olubukola, Wang, Ben X, Vila-Casadesús, Maria, Yang, S Y Cindy, Berman, Hal, Vivancos, Ana, Lam, Bernard, Lungu, Ilinca, Salawu, Abdulazeez, Stayner, Lee-Anne, Haibe-Kains, Benjamin, Bedard, Philippe L., Avery, Lisa, Abdul Razak, Albiruni Ryan, Pugh, Trevor John, Spreafico, Anna, Siu, Lillian L., Hansen, Aaron Richard
Published in JCO global oncology (01.08.2023)
Published in JCO global oncology (01.08.2023)
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Phase I pharmacokinetic study of single agent trametinib in advanced cancer patients with hepatic dysfunction: An NCI Organ Dysfunction Working Group (ODWG) study
Spreafico, Anna, Chen, Eric, Sahebjam, Solmaz, Renouf, Daniel John, Kelly, Karen, Lockhart, Albert C., Vaishampayan, Ulka N., Hotte, Sebastien J., Razak, Albiruni R., Wang, Lisa, Stayner, Lee-Anne, Bougie, Alanna, Chen, Helen X., Ivy, S. Percy, Siu, Lillian L.
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Journal Article
Final report of a phase I study of veliparib (ABT-888) in combination with low-dose fractionated whole abdominal radiation therapy (LDFWAR) in patients with advanced solid malignancies and peritoneal carcinomatosis with a dose escalation in ovarian and fallopian tube cancers
Reiss, Kim Anna, Herman, Joseph M., Zahurak, Marianna, Fyles, Anthony W., Milosevic, Michael F., Scardina, Angela, Joffe, Caitlin, Petito, Emily, Hacker-Prietz, Amy, Chen, Alice P., Temkin, Sarah Madhu, Horiba, Naomi, Kinders, Robert J., Wang, Lihua, Stayner, Lee-Anne, Azad, Nilofer Saba
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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