The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer
O'Hayre, Morgan, Vázquez-Prado, José, Kufareva, Irina, Stawiski, Eric W., Handel, Tracy M., Seshagiri, Somasekar, Gutkind, J. Silvio
Published in Nature reviews. Cancer (01.06.2013)
Published in Nature reviews. Cancer (01.06.2013)
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Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations
Bueno, Raphael, Stawiski, Eric W, Goldstein, Leonard D, Durinck, Steffen, De Rienzo, Assunta, Modrusan, Zora, Gnad, Florian, Nguyen, Thong T, Jaiswal, Bijay S, Chirieac, Lucian R, Sciaranghella, Daniele, Dao, Nhien, Gustafson, Corinne E, Munir, Kiara J, Hackney, Jason A, Chaudhuri, Amitabha, Gupta, Ravi, Guillory, Joseph, Toy, Karen, Ha, Connie, Chen, Ying-Jiun, Stinson, Jeremy, Chaudhuri, Subhra, Zhang, Na, Wu, Thomas D, Sugarbaker, David J, de Sauvage, Frederic J, Richards, William G, Seshagiri, Somasekar
Published in Nature genetics (01.04.2016)
Published in Nature genetics (01.04.2016)
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The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins
Suryamohan, Kushal, Krishnankutty, Sajesh P., Guillory, Joseph, Jevit, Matthew, Schröder, Markus S., Wu, Meng, Kuriakose, Boney, Mathew, Oommen K., Perumal, Rajadurai C., Koludarov, Ivan, Goldstein, Leonard D., Senger, Kate, Dixon, Mandumpala Davis, Velayutham, Dinesh, Vargas, Derek, Chaudhuri, Subhra, Muraleedharan, Megha, Goel, Ridhi, Chen, Ying-Jiun J., Ratan, Aakrosh, Liu, Peter, Faherty, Brendan, de la Rosa, Guillermo, Shibata, Hiroki, Baca, Miriam, Sagolla, Meredith, Ziai, James, Wright, Gus A., Vucic, Domagoj, Mohan, Sangeetha, Antony, Aju, Stinson, Jeremy, Kirkpatrick, Donald S., Hannoush, Rami N., Durinck, Steffen, Modrusan, Zora, Stawiski, Eric W., Wiley, Kristen, Raudsepp, Terje, Kini, R. Manjunatha, Zachariah, Arun, Seshagiri, Somasekar
Published in Nature genetics (01.01.2020)
Published in Nature genetics (01.01.2020)
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ERK mutations and amplification confer resistance to ERK-inhibitor therapy
Jaiswal, Bijay S, Durinck, Steffen, Stawiski, Eric, Yin, Jianping, Wang, Weiru, Lin, Eva, Moffat, John G, Martin, Scott, Modrusan, Zora, Seshagiri, Somasekar
Published in Clinical cancer research (15.08.2018)
Published in Clinical cancer research (15.08.2018)
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Oncogenic ERBB3 Mutations in Human Cancers
Jaiswal, Bijay S., Kljavin, Noelyn M., Stawiski, Eric W., Chan, Emily, Parikh, Chaitali, Durinck, Steffen, Chaudhuri, Subhra, Pujara, Kanan, Guillory, Joseph, Edgar, Kyle A., Janakiraman, Vasantharajan, Scholz, Rolf-Peter, Bowman, Krista K., Lorenzo, Maria, Li, Hong, Wu, Jiansheng, Yuan, Wenlin, Peters, Brock A., Kan, Zhengyan, Stinson, Jeremy, Mak, Michelle, Modrusan, Zora, Eigenbrot, Charles, Firestein, Ron, Stern, Howard M., Rajalingam, Krishnaraj, Schaefer, Gabriele, Merchant, Mark A., Sliwkowski, Mark X., de Sauvage, Frederic J., Seshagiri, Somasekar
Published in Cancer cell (13.05.2013)
Published in Cancer cell (13.05.2013)
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Spectrum of diverse genomic alterations define non–clear cell renal carcinoma subtypes
Durinck, Steffen, Stawiski, Eric W, Pavía-Jiménez, Andrea, Modrusan, Zora, Kapur, Payal, Jaiswal, Bijay S, Zhang, Na, Toffessi-Tcheuyap, Vanina, Nguyen, Thong T, Pahuja, Kanika Bajaj, Chen, Ying-Jiun, Saleem, Sadia, Chaudhuri, Subhra, Heldens, Sherry, Jackson, Marlena, Peña-Llopis, Samuel, Guillory, Joseph, Toy, Karen, Ha, Connie, Harris, Corissa J, Holloman, Eboni, Hill, Haley M, Stinson, Jeremy, Rivers, Celina Sanchez, Janakiraman, Vasantharajan, Wang, Weiru, Kinch, Lisa N, Grishin, Nick V, Haverty, Peter M, Chow, Bernard, Gehring, Julian S, Reeder, Jens, Pau, Gregoire, Wu, Thomas D, Margulis, Vitaly, Lotan, Yair, Sagalowsky, Arthur, Pedrosa, Ivan, de Sauvage, Frederic J, Brugarolas, James, Seshagiri, Somasekar
Published in Nature genetics (2015)
Published in Nature genetics (2015)
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Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
Rudin, Charles M, Durinck, Steffen, Stawiski, Eric W, Poirier, John T, Modrusan, Zora, Shames, David S, Bergbower, Emily A, Guan, Yinghui, Shin, James, Guillory, Joseph, Rivers, Celina Sanchez, Foo, Catherine K, Bhatt, Deepali, Stinson, Jeremy, Gnad, Florian, Haverty, Peter M, Gentleman, Robert, Chaudhuri, Subhra, Janakiraman, Vasantharajan, Jaiswal, Bijay S, Parikh, Chaitali, Yuan, Wenlin, Zhang, Zemin, Koeppen, Hartmut, Wu, Thomas D, Stern, Howard M, Yauch, Robert L, Huffman, Kenneth E, Paskulin, Diego D, Illei, Peter B, Varella-Garcia, Marileila, Gazdar, Adi F, de Sauvage, Frederic J, Bourgon, Richard, Minna, John D, Brock, Malcolm V, Seshagiri, Somasekar
Published in Nature genetics (01.10.2012)
Published in Nature genetics (01.10.2012)
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Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations
Pahuja, Kanika Bajaj, Nguyen, Thong T., Jaiswal, Bijay S., Prabhash, Kumar, Thaker, Tarjani M., Senger, Kate, Chaudhuri, Subhra, Kljavin, Noelyn M., Antony, Aju, Phalke, Sameer, Kumar, Prasanna, Mravic, Marco, Stawiski, Eric W., Vargas, Derek, Durinck, Steffen, Gupta, Ravi, Khanna-Gupta, Arati, Trabucco, Sally E., Sokol, Ethan S., Hartmaier, Ryan J., Singh, Ashish, Chougule, Anuradha, Trivedi, Vaishakhi, Dutt, Amit, Patil, Vijay, Joshi, Amit, Noronha, Vanita, Ziai, James, Banavali, Sripad D., Ramprasad, Vedam, DeGrado, William F., Bueno, Raphael, Jura, Natalia, Seshagiri, Somasekar
Published in Cancer cell (12.11.2018)
Published in Cancer cell (12.11.2018)
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A comprehensive transcriptional portrait of human cancer cell lines
Klijn, Christiaan, Durinck, Steffen, Stawiski, Eric W, Haverty, Peter M, Jiang, Zhaoshi, Liu, Hanbin, Degenhardt, Jeremiah, Mayba, Oleg, Gnad, Florian, Liu, Jinfeng, Pau, Gregoire, Reeder, Jens, Cao, Yi, Mukhyala, Kiran, Selvaraj, Suresh K, Yu, Mamie, Zynda, Gregory J, Brauer, Matthew J, Wu, Thomas D, Gentleman, Robert C, Manning, Gerard, Yauch, Robert L, Bourgon, Richard, Stokoe, David, Modrusan, Zora, Neve, Richard M, de Sauvage, Frederic J, Settleman, Jeffrey, Seshagiri, Somasekar, Zhang, Zemin
Published in Nature biotechnology (01.03.2015)
Published in Nature biotechnology (01.03.2015)
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SCINA: A Semi-Supervised Subtyping Algorithm of Single Cells and Bulk Samples
Zhang, Ze, Luo, Danni, Zhong, Xue, Choi, Jin Huk, Ma, Yuanqing, Wang, Stacy, Mahrt, Elena, Guo, Wei, Stawiski, Eric W, Modrusan, Zora, Seshagiri, Somasekar, Kapur, Payal, Hon, Gary C, Brugarolas, James, Wang, Tao
Published in Genes (12.07.2019)
Published in Genes (12.07.2019)
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Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function
Storm, Elaine E., Durinck, Steffen, de Sousa e Melo, Felipe, Tremayne, Jarrod, Kljavin, Noelyn, Tan, Christine, Ye, Xiaofen, Chiu, Cecilia, Pham, Thinh, Hongo, Jo-Anne, Bainbridge, Travis, Firestein, Ron, Blackwood, Elizabeth, Metcalfe, Ciara, Stawiski, Eric W., Yauch, Robert L., Wu, Yan, de Sauvage, Frederic J.
Published in Nature (London) (07.01.2016)
Published in Nature (London) (07.01.2016)
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Recurrent R-spondin fusions in colon cancer
Seshagiri, Somasekar, Stawiski, Eric W., Durinck, Steffen, Modrusan, Zora, Storm, Elaine E., Conboy, Caitlin B., Chaudhuri, Subhra, Guan, Yinghui, Janakiraman, Vasantharajan, Jaiswal, Bijay S., Guillory, Joseph, Ha, Connie, Dijkgraaf, Gerrit J. P., Stinson, Jeremy, Gnad, Florian, Huntley, Melanie A., Degenhardt, Jeremiah D., Haverty, Peter M., Bourgon, Richard, Wang, Weiru, Koeppen, Hartmut, Gentleman, Robert, Starr, Timothy K., Zhang, Zemin, Largaespada, David A., Wu, Thomas D., de Sauvage, Frederic J.
Published in Nature (London) (30.08.2012)
Published in Nature (London) (30.08.2012)
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Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas
Krishnan, Aswini, Berthelet, Jean, Renaud, Emilie, Rosigkeit, Sebastian, Distler, Ute, Stawiski, Eric, Wang, Jing, Modrusan, Zora, Fiedler, Marc, Bienz, Mariann, Tenzer, Stefan, Schad, Arno, Roth, Wilfried, Thiede, Bernd, Seshagiri, Somasekar, Musholt, Thomas J., Rajalingam, Krishnaraj
Published in Nature communications (28.04.2020)
Published in Nature communications (28.04.2020)
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Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2
Suryamohan, Kushal, Diwanji, Devan, Stawiski, Eric W., Gupta, Ravi, Miersch, Shane, Liu, Jiang, Chen, Chao, Jiang, Ying-Ping, Fellouse, Frederic A., Sathirapongsasuti, J. Fah, Albers, Patrick K., Deepak, Tanneeru, Saberianfar, Reza, Ratan, Aakrosh, Washburn, Gavin, Mis, Monika, Santhosh, Devi, Somasekar, Sneha, Hiranjith, G. H., Vargas, Derek, Mohan, Sangeetha, Phalke, Sameer, Kuriakose, Boney, Antony, Aju, Ustav Jr, Mart, Schuster, Stephan C., Sidhu, Sachdev, Junutula, Jagath R., Jura, Natalia, Seshagiri, Somasekar
Published in Communications biology (12.04.2021)
Published in Communications biology (12.04.2021)
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An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors
Wang, Tao, Lu, Rong, Kapur, Payal, Jaiswal, Bijay S, Hannan, Raquibul, Zhang, Ze, Pedrosa, Ivan, Luke, Jason J, Zhang, He, Goldstein, Leonard D, Yousuf, Qurratulain, Gu, Yi-Feng, McKenzie, Tiffani, Joyce, Allison, Kim, Min S, Wang, Xinlei, Luo, Danni, Onabolu, Oreoluwa, Stevens, Christina, Xie, Zhiqun, Chen, Mingyi, Filatenkov, Alexander, Torrealba, Jose, Luo, Xin, Guo, Wenbin, He, Jingxuan, Stawiski, Eric, Modrusan, Zora, Durinck, Steffen, Seshagiri, Somasekar, Brugarolas, James
Published in Cancer discovery (01.09.2018)
Published in Cancer discovery (01.09.2018)
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Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors
Savill, Kristin M. Zimmerman, Lee, Brian B., Oeh, Jason, Lin, Jie, Lin, Eva, Chung, Wei-Jen, Young, Amy, Chen, Wennie, Miś, Monika, Mesh, Kathryn, Eastham, Jeffrey, Gnad, Florian, Jiang, Zhaoshi, Stawiski, Eric W., Haley, Benjamin, Daemen, Anneleen, Wang, Xiaojing, Koeppen, Hartmut, Modrusan, Zora, Martin, Scott E., Sampath, Deepak, Lin, Kui
Published in Nature communications (19.04.2022)
Published in Nature communications (19.04.2022)
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Comprehensive genomic analysis identifies pathogenic variants in maturity-onset diabetes of the young (MODY) patients in South India
Mohan, Viswanathan, Radha, Venkatesan, Nguyen, Thong T, Stawiski, Eric W, Pahuja, Kanika Bajaj, Goldstein, Leonard D, Tom, Jennifer, Anjana, Ranjit Mohan, Kong-Beltran, Monica, Bhangale, Tushar, Jahnavi, Suresh, Chandni, Radhakrishnan, Gayathri, Vijay, George, Paul, Zhang, Na, Murugan, Sakthivel, Phalke, Sameer, Chaudhuri, Subhra, Gupta, Ravi, Zhang, Jingli, Santhosh, Sam, Stinson, Jeremy, Modrusan, Zora, Ramprasad, V L, Seshagiri, Somasekar, Peterson, Andrew S
Published in BMC medical genetics (13.02.2018)
Published in BMC medical genetics (13.02.2018)
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Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer
Liu, Jinfeng, McCleland, Mark, Stawiski, Eric W., Gnad, Florian, Mayba, Oleg, Haverty, Peter M., Durinck, Steffen, Chen, Ying-Jiun, Klijn, Christiaan, Jhunjhunwala, Suchit, Lawrence, Michael, Liu, Hanbin, Wan, Yinan, Chopra, Vivek, Yaylaoglu, Murat B., Yuan, Wenlin, Ha, Connie, Gilbert, Houston N., Reeder, Jens, Pau, Gregoire, Stinson, Jeremy, Stern, Howard M., Manning, Gerard, Wu, Thomas D., Neve, Richard M., de Sauvage, Frederic J., Modrusan, Zora, Seshagiri, Somasekar, Firestein, Ron, Zhang, Zemin
Published in Nature communications (08.05.2014)
Published in Nature communications (08.05.2014)
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S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis
Yuan, Wenlin, Goldstein, Leonard D, Durinck, Steffen, Chen, Ying-Jiun, Nguyen, Thong T, Kljavin, Noelyn M, Sokol, Ethan S, Stawiski, Eric W, Haley, Benjamin, Ziai, James, Modrusan, Zora, Seshagiri, Somasekar
Published in Breast cancer research : BCR (27.12.2019)
Published in Breast cancer research : BCR (27.12.2019)
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Diverse modes of genomic alteration in hepatocellular carcinoma
Jhunjhunwala, Suchit, Jiang, Zhaoshi, Stawiski, Eric W, Gnad, Florian, Liu, Jinfeng, Mayba, Oleg, Du, Pan, Diao, Jingyu, Johnson, Stephanie, Wong, Kwong-Fai, Gao, Zhibo, Li, Yingrui, Wu, Thomas D, Kapadia, Sharookh B, Modrusan, Zora, French, Dorothy M, Luk, John M, Seshagiri, Somasekar, Zhang, Zemin
Published in Genome biology (26.08.2014)
Published in Genome biology (26.08.2014)
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