A targeted amplicon next-generation sequencing assay for tryptase genotyping to support personalized therapy in mast cell-related disorders
Li, Olga, Hackney, Jason A, Choy, David F, Chang, Diana, Nersesian, Rhea, Staton, Tracy L, Cai, Fang, Toghi Eshghi, Shadi
Published in PloS one (09.02.2024)
Published in PloS one (09.02.2024)
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Journal Article
A whole genome sequencing study of moderate to severe asthma identifies a lung function locus associated with asthma risk
Chang, Diana, Hunkapiller, Julie, Bhangale, Tushar, Reeder, Jens, Mukhyala, Kiran, Tom, Jennifer, Cowgill, Amy, Vogel, Jan, Forrest, William F, Khan, Zia, Stockwell, Amy, McCarthy, Mark I, Staton, Tracy L, Olsson, Julie, Holweg, Cecile T J, Cheung, Dorothy S, Chen, Hubert, Brauer, Matthew J, Graham, Robert R, Behrens, Timothy, Wilson, Mark S, Arron, Joseph R, Choy, David F, Yaspan, Brian L
Published in Scientific reports (02.04.2022)
Published in Scientific reports (02.04.2022)
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A phase I, randomized, observer-blinded, single and multiple ascending-dose study to investigate the safety, pharmacokinetics, and immunogenicity of BITS7201A, a bispecific antibody targeting IL-13 and IL-17, in healthy volunteers
Staton, Tracy L, Peng, Kun, Owen, Ryan, Choy, David F, Cabanski, Christopher R, Fong, Alice, Brunstein, Flavia, Alatsis, Kathila R, Chen, Hubert
Published in BMC pulmonary medicine (07.01.2019)
Published in BMC pulmonary medicine (07.01.2019)
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Journal Article
Seasonal Variability of Severe Asthma Exacerbations and Clinical Benefit from Lebrikizumab
Staton, Tracy L., PhD, Arron, Joseph R., MD, PhD, Olsson, Julie, MD, MS, Holweg, Cécile TJ., PhD, Matthews, John G., MB, BS, PhD, Choy, David F., BS
Published in Journal of allergy and clinical immunology (01.05.2017)
Published in Journal of allergy and clinical immunology (01.05.2017)
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Journal Article
A mechanistic PK/PD model to enable dose selection of the potent anti‐tryptase antibody (MTPS9579A) in patients with moderate‐to‐severe asthma
Rymut, Sharon M., Henderson, Lindsay M., Poon, Victor, Staton, Tracy L., Cai, Fang, Sukumaran, Siddharth, Rhee, Horace, Owen, Ryan, Ramanujan, Saroja, Yoshida, Kenta
Published in Clinical and translational science (01.04.2023)
Published in Clinical and translational science (01.04.2023)
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Journal Article
Dose‐dependent inactivation of airway tryptase with a novel dissociating anti‐tryptase antibody (MTPS9579A) in healthy participants: A randomized trial
Rymut, Sharon M., Sukumaran, Siddharth, Sperinde, Gizette, Bremer, Meire, Galanter, Joshua, Yoshida, Kenta, Smith, Jordan, Banerjee, Prajna, Sverkos, Viyia, Cai, Fang, Steffen, Verena, Henderson, Lindsay M., Rhee, Horace, Belloni, Paula N., Lin, Joseph H., Staton, Tracy L.
Published in Clinical and translational science (01.02.2022)
Published in Clinical and translational science (01.02.2022)
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Journal Article
Development of a multi-matrix LC–MS/MS method for urea quantitation and its application in human respiratory disease studies
Wang, Jianshuang, Gao, Yang, Dorshorst, Drew W., Cai, Fang, Bremer, Meire, Milanowski, Dennis, Staton, Tracy L., Cape, Stephanie S., Dean, Brian, Ding, Xiao
Published in Journal of pharmaceutical and biomedical analysis (30.01.2017)
Published in Journal of pharmaceutical and biomedical analysis (30.01.2017)
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Journal Article
CD8 + recent thymic emigrants home to and efficiently repopulate the small intestine epithelium
Butcher, Eugene C, Staton, Tracy L, Habtezion, Aida, Winslow, Monte M, Sato, Tohru, Love, Paul E
Published in Nature immunology (01.05.2006)
Published in Nature immunology (01.05.2006)
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Journal Article
Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial
Kelsen, Steven G., Agache, Ioana O., Soong, Weily, Israel, Elliot, Chupp, Geoffrey L., Cheung, Dorothy S., Theess, Wiebke, Yang, Xiaoying, Staton, Tracy L., Choy, David F., Fong, Alice, Dash, Ajit, Dolton, Michael, Pappu, Rajita, Brightling, Christopher E.
Published in Journal of allergy and clinical immunology (01.09.2021)
Published in Journal of allergy and clinical immunology (01.09.2021)
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Journal Article
Seasonal variability of lung function and Asthma Quality of Life Questionnaire Scores in adults with uncontrolled asthma
N Bauer, Rebecca, Yang, Xiaoying, L Staton, Tracy, Olsson, Julie, Holweg, Cecile T J, R Arron, Joseph, Matthews, John G, Choy, David F
Published in BMJ open respiratory research (2019)
Published in BMJ open respiratory research (2019)
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Journal Article
iNKT Cells Require CCR4 to Localize to the Airways and to Induce Airway Hyperreactivity
Meyer, Everett H, Wurbel, Marc-Andre, Staton, Tracy L, Pichavant, Muriel, Kan, Matthew J, Savage, Paul B, DeKruyff, Rosemarie H, Butcher, Eugene C, Campbell, James J, Umetsu, Dale T
Published in Journal of Immunology (01.10.2007)
Published in Journal of Immunology (01.10.2007)
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Journal Article
An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma
Maun, Henry R., Jackman, Janet K., Choy, David F., Loyet, Kelly M., Staton, Tracy L., Jia, Guiquan, Dressen, Amy, Hackney, Jason A., Bremer, Meire, Walters, Benjamin T., Vij, Rajesh, Chen, Xiaocheng, Trivedi, Neil N., Morando, Ashley, Lipari, Michael T., Franke, Yvonne, Wu, Xiumin, Zhang, Juan, Liu, John, Wu, Ping, Chang, Diana, Orozco, Luz D., Christensen, Erin, Wong, Manda, Corpuz, Racquel, Hang, Julie Q., Lutman, Jeff, Sukumaran, Siddharth, Wu, Yan, Ubhayakar, Savita, Liang, Xiaorong, Schwartz, Lawrence B., Babina, Magda, Woodruff, Prescott G., Fahy, John V., Ahuja, Rahul, Caughey, George H., Kusi, Aija, Dennis, Mark S., Eigenbrot, Charles, Kirchhofer, Daniel, Austin, Cary D., Wu, Lawren C., Koerber, James T., Lee, Wyne P., Yaspan, Brian L., Alatsis, Kathila R., Arron, Joseph R., Lazarus, Robert A., Yi, Tangsheng
Published in Cell (03.10.2019)
Published in Cell (03.10.2019)
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Journal Article
Airway tryptase levels inform the lack of clinical efficacy of the tryptase inhibitor MTPS9579A in asthma
Rhee, Horace, Henderson, Lindsay M., Bauer, Rebecca N., Wong, Kit, Staton, Tracy L., Choy, David F., Banerjee, Prajna, Poon, Victor, Yoshida, Kenta, Chen, Chen, Long, Keyi, Sperinde, Gizette, Laing, Steven T., Jones, Nicholas S., Glickstein, Sara B., Dayal, Parul, Fong, Alice, Dash, Ajit, Pulka, Grazyna, Leaker, Brian, Singh, Dave, Bradding, Peter
Published in Allergy (Copenhagen) (09.09.2024)
Published in Allergy (Copenhagen) (09.09.2024)
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Measurement of IL-17AA and IL-17FF as Pharmacodynamic Biomarkers to Demonstrate Target Engagement in the Phase I Study of MCAF5352A
Peng, Kun, Wang, Yehong, Siradze, Ketevan, Erickson, Rich, Fischer, Saloumeh K., Staton, Tracy L.
Published in The AAPS journal (01.01.2019)
Published in The AAPS journal (01.01.2019)
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Journal Article
The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells
Glimcher, Laurie H, Lazarevic, Vanja, Zullo, Alfred J, Gallo, Elena M, Crabtree, Gerald R, Staton, Tracy L, Schweitzer, Michelle N
Published in Nature immunology (01.03.2009)
Published in Nature immunology (01.03.2009)
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Journal Article
An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma
Maun, Henry R., Jackman, Janet K., Choy, David F., Loyet, Kelly M., Staton, Tracy L., Jia, Guiquan, Dressen, Amy, Hackney, Jason A., Bremer, Meire, Walters, Benjamin T., Vij, Rajesh, Chen, Xiaocheng, Trivedi, Neil N., Morando, Ashley, Lipari, Michael T., Franke, Yvonne, Wu, Xiumin, Zhang, Juan, Liu, John, Wu, Ping, Chang, Diana, Orozco, Luz D., Christensen, Erin, Wong, Manda, Corpuz, Racquel, Hang, Julie Q., Lutman, Jeff, Sukumaran, Siddharth, Wu, Yan, Ubhayakar, Savita, Liang, Xiaorong, Schwartz, Lawrence B., Babina, Magda, Woodruff, Prescott G., Fahy, John V., Ahuja, Rahul, Caughey, George H., Kusi, Aija, Dennis, Mark S., Eigenbrot, Charles, Kirchhofer, Daniel, Austin, Cary D., Wu, Lawren C., Koerber, James T., Lee, Wyne P., Yaspan, Brian L., Alatsis, Kathila R., Arron, Joseph R., Lazarus, Robert A., Yi, Tangsheng
Published in Cell (23.01.2020)
Published in Cell (23.01.2020)
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Journal Article
Dampening of death pathways by schnurri―2 is essential for T―cell development
STATON, Tracy L, LAZAREVIC, Vanja, JONES, Dallas C, LANSER, Amanda J, TAKAGI, Tsuyoshi, ISHII, Shunsuke, GLIMCHERL, Laurie H
Published in Nature (London) (07.04.2011)
Published in Nature (London) (07.04.2011)
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