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Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism
Zanin-Zhorov, Alexandra, Weiss, Jonathan M., Nyuydzefe, Melanie S., Chen, Wei, Scher, Jose U., Mo, Rigen, Depoil, David, Rao, Nishta, Liu, Ben, Wei, Jianlu, Lucas, Sarah, Koslow, Matthew, Roche, Maria, Schueller, Olivier, Weiss, Sara, Poyurovsky, Masha V., Tonra, James, Hippen, Keli L, Dustin, Michael L., Blazar, Bruce R., Liu, Chuan-ju, Waksal, Samuel D., Dinarello, Charles A.
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2014)
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T helper 17 cell heterogeneity and pathogenicity in autoimmune disease
Ghoreschi, Kamran, Laurence, Arian, Yang, Xiang-Ping, Hirahara, Kiyoshi, O'Shea, John J.
Published in Trends in immunology (01.09.2011)
Published in Trends in immunology (01.09.2011)
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TLR9-Targeted STAT3 Silencing Abrogates Immunosuppressive Activity of Myeloid-Derived Suppressor Cells from Prostate Cancer Patients
Hossain, Dewan M. S., Pal, Sumanta K., Moreira, Dayson, Duttagupta, Priyanka, Zhang, Qifang, Won, Haejung, Jones, Jeremy, D'Apuzzo, Massimo, Forman, Stephen, Kortylewski, Marcin
Published in Clinical cancer research (15.08.2015)
Published in Clinical cancer research (15.08.2015)
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MicroRNA-155-5p is associated with oral squamous cell carcinoma metastasis and poor prognosis
Baba, Osamu, Hasegawa, Shogo, Nagai, Hiroki, Uchida, Fumihiko, Yamatoji, Masanobu, Kanno, Naomi I., Yamagata, Kenji, Sakai, Satoshi, Yanagawa, Toru, Bukawa, Hiroki
Published in Journal of oral pathology & medicine (01.04.2016)
Published in Journal of oral pathology & medicine (01.04.2016)
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IL-6 blockade by monoclonal antibodies inhibits apolipoprotein (a) expression and lipoprotein (a) synthesis in humans
Müller, Nike, Schulte, Dominik M., Türk, Kathrin, Freitag-Wolf, Sandra, Hampe, Jochen, Zeuner, Rainald, Schröder, Johann O., Gouni-Berthold, Ioanna, Berthold, Heiner K., Krone, Wilhelm, Rose-John, Stefan, Schreiber, Stefan, Laudes, Matthias
Published in Journal of lipid research (01.05.2015)
Published in Journal of lipid research (01.05.2015)
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Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway
Zhuang, Guanglei, Wu, Xiumin, Jiang, Zhaoshi, Kasman, Ian, Yao, Jenny, Guan, Yinghui, Oeh, Jason, Modrusan, Zora, Bais, Carlos, Sampath, Deepak, Ferrara, Napoleone
Published in The EMBO journal (29.08.2012)
Published in The EMBO journal (29.08.2012)
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Paracrine IL-6 signaling mediates the effects of pancreatic stellate cells on epithelial-mesenchymal transition via Stat3/Nrf2 pathway in pancreatic cancer cells
Wu, Yuan Seng, Chung, Ivy, Wong, Won Fen, Masamune, Atsushi, Sim, Maw Shin, Looi, Chung Yeng
Published in Biochimica et biophysica acta. General subjects (01.02.2017)
Published in Biochimica et biophysica acta. General subjects (01.02.2017)
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STAT3-orchestrated gene expression signatures and tumor microenvironment in esophageal squamous cell carcinoma uncovered by single-cell sequencing
Pang, Shilian, Chen, Yurao, Zheng, Zemao, Wang, Luoshai, Chen, Ronghuai, He, Ming, Zhao, Xiang, Yao, Juan, Jin, Liyan
Published in Biochimica et biophysica acta. General subjects (01.05.2025)
Published in Biochimica et biophysica acta. General subjects (01.05.2025)
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Pathobiont-driven antibody sialylation through IL-10 undermines vaccination
Tsai, Chih-Ming, Hajam, Irshad A., Caldera, J.R., Chiang, Austin W.T., Gonzalez, Cesia, Du, Choudhruy, Biswa, Li, Haining, Suzuki, Emi, Askarian, Fatemeh, Clark, Ty’Tianna, Lin, Brian, Wierzbicki, Igor H., Riestra, Angelica M., Conrad, Douglas J., Gonzalez, David J., Nizet, Victor, Lewis, Nathan E., Liu, George Y.
Published in The Journal of clinical investigation (16.12.2024)
Published in The Journal of clinical investigation (16.12.2024)
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FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3–CCL2 Signaling
Yang, Xuguang, Lin, Yuli, Shi, Yinghong, Li, Bingji, Liu, Weiren, Yin, Wei, Dang, Yongjun, Chu, Yiwei, Fan, Jia, He, Rui
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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MiR-125-5p/IL-6R axis regulates macrophage inflammatory response and intestinal epithelial cell apoptosis in ulcerative colitis through JAK1/STAT3 and NF-κB pathway
Yao, Danhua, Zhou, Zhiyuan, Wang, Pengfei, Zheng, Lei, Huang, Yuhua, Duan, Yantao, Liu, Bin, Li, Yousheng
Published in Cell cycle (Georgetown, Tex.) (02.12.2021)
Published in Cell cycle (Georgetown, Tex.) (02.12.2021)
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Tuberculosis Exacerbates HIV-1 Infection through IL-10/STAT3-Dependent Tunneling Nanotube Formation in Macrophages
Souriant, Shanti, Balboa, Luciana, Dupont, Maeva, Pingris, Karine, Kviatcovsky, Denise, Cougoule, Céline, Lastrucci, Claire, Bah, Aicha, Gasser, Romain, Poincloux, Renaud, Raynaud-Messina, Brigitte, Al Saati, Talal, Inwentarz, Sandra, Poggi, Susana, Moraña, Eduardo Jose, González-Montaner, Pablo, Corti, Marcelo, Lagane, Bernard, Vergne, Isabelle, Allers, Carolina, Kaushal, Deepak, Kuroda, Marcelo J., Sasiain, Maria del Carmen, Neyrolles, Olivier, Maridonneau-Parini, Isabelle, Lugo-Villarino, Geanncarlo, Vérollet, Christel
Published in Cell reports (Cambridge) (26.03.2019)
Published in Cell reports (Cambridge) (26.03.2019)
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Programmed death-1–induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection
Said, Elias A, Dupuy, Franck P, Trautmann, Lydie, Zhang, Yuwei, Shi, Yu, El-Far, Mohamed, Hill, Brenna J, Noto, Alessandra, Ancuta, Petronela, Peretz, Yoav, Fonseca, Simone G, Van Grevenynghe, Julien, Boulassel, Mohamed R, Bruneau, Julie, Shoukry, Naglaa H, Routy, Jean-Pierre, Douek, Daniel C, Haddad, Elias K, Sekaly, Rafick-Pierre
Published in Nature medicine (01.04.2010)
Published in Nature medicine (01.04.2010)
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Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
Fraietta, Joseph A, Lacey, Simon F, Orlando, Elena J, Pruteanu-Malinici, Iulian, Gohil, Mercy, Lundh, Stefan, Boesteanu, Alina C, Wang, Yan, O'Connor, Roddy S, Hwang, Wei-Ting, Pequignot, Edward, Ambrose, David E, Zhang, Changfeng, Wilcox, Nicholas, Bedoya, Felipe, Dorfmeier, Corin, Chen, Fang, Tian, Lifeng, Parakandi, Harit, Gupta, Minnal, Young, Regina M, Johnson, F Brad, Kulikovskaya, Irina, Liu, Li, Xu, Jun, Kassim, Sadik H, Davis, Megan M, Levine, Bruce L, Frey, Noelle V, Siegel, Donald L, Huang, Alexander C, Wherry, E John, Bitter, Hans, Brogdon, Jennifer L, Porter, David L, June, Carl H, Melenhorst, J Joseph
Published in Nature medicine (01.05.2018)
Published in Nature medicine (01.05.2018)
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Role of STAT3 in skin fibrosis and transforming growth factor beta signalling
Pedroza, Mesias, To, Sarah, Assassi, Shervin, Wu, Minghua, Tweardy, David, Agarwal, Sandeep K
Published in Rheumatology (Oxford, England) (01.10.2018)
Published in Rheumatology (Oxford, England) (01.10.2018)
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Diminished allergic disease in patients with STAT3 mutations reveals a role for STAT3 signaling in mast cell degranulation
Siegel, Andrea M., Stone, Kelly D., Cruse, Glenn, Lawrence, Monica G., Olivera, Ana, Jung, Mi-yeon, Barber, John S., Freeman, Alexandra F., Holland, Steven M., O'Brien, Michelle, Jones, Nina, Wisch, Laura B., Kong, Heidi H., Desai, Avanti, Farber, Orly, Gilfillan, Alasdair M., Rivera, Juan, Milner, Joshua D.
Published in Journal of allergy and clinical immunology (01.12.2013)
Published in Journal of allergy and clinical immunology (01.12.2013)
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The IL-6-neutralizing sIL-6R-sgp130 buffer system is disturbed in patients with type 2 diabetes
Aparicio-Siegmund, Samadhi, Garbers, Yvonne, Flynn, Charlotte M., Waetzig, Georg H., Gouni-Berthold, Ioanna, Krone, Wilhelm, Berthold, Heiner K., Laudes, Matthias, Rose-John, Stefan, Garbers, Christoph
Published in American journal of physiology: endocrinology and metabolism (01.08.2019)
Published in American journal of physiology: endocrinology and metabolism (01.08.2019)
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Modulation of STAT-3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of Treg cells
Ju, Ji Hyeon, Heo, Yu-Jung, Cho, Mi-La, Jhun, Joo-Yeon, Park, Jin-Sil, Lee, Seon-Yeong, Oh, Hye-Jwa, Moon, Su-Jin, Kwok, Seung-Ki, Park, Kyung-Su, Park, Sung-Hwan, Kim, Ho-Youn
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.11.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.11.2012)
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Signal transducer and activator of transcription 3 signaling in tumor immune evasion
Zhang, Luying, Kuca, Kamil, You, Li, Zhao, Yingying, Musilek, Kamil, Nepovimova, Eugenie, Wu, Qinghua, Wu, Wenda, Adam, Vojtech
Published in Pharmacology & therapeutics (Oxford) (01.02.2022)
Published in Pharmacology & therapeutics (Oxford) (01.02.2022)
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