The JAK-STAT pathway at 30: Much learned, much more to do
Philips, Rachael L., Wang, Yuxin, Cheon, HyeonJoo, Kanno, Yuka, Gadina, Massimo, Sartorelli, Vittorio, Horvath, Curt M., Darnell, James E., Stark, George R., O’Shea, John J.
Published in Cell (13.10.2022)
Published in Cell (13.10.2022)
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Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis
Liao, Yun, Zhao, Junjie, Bulek, Katarzyna, Tang, Fangqiang, Chen, Xing, Cai, Gang, Jia, Shang, Fox, Paul L, Huang, Emina, Pizarro, Theresa T, Kalady, Matthew F, Jackson, Mark W, Bao, Shideng, Sen, Ganes C, Stark, George R, Chang, Christopher J, Li, Xiaoxia
Published in Nature communications (14.02.2020)
Published in Nature communications (14.02.2020)
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Journal Article
Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
Tao, Weiwei, Chu, Chengwei, Zhou, Wenchao, Huang, Zhi, Zhai, Kui, Fang, Xiaoguang, Huang, Qian, Zhang, Aili, Wang, Xiuxing, Yu, Xingjiang, Huang, Haidong, Wu, Qiulian, Sloan, Andrew E, Yu, Jennifer S, Li, Xiaoxia, Stark, George R, Rich, Jeremy N, Bao, Shideng
Published in Nature communications (15.06.2020)
Published in Nature communications (15.06.2020)
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Journal Article
STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor
Wang, Yuxin, van Boxel-Dezaire, Anette H. H., Cheon, HyeonJoo, Yang, Jinbo, Stark, George R.
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2013)
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Journal Article
PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB
Wei, Han, Wang, Benlian, Miyagi, Masaru, She, Yun, Gopalan, Banu, Huang, De-Bin, Ghosh, Gourisankar, Stark, George R., Lu, Tao
Published in Proceedings of the National Academy of Sciences - PNAS (13.08.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (13.08.2013)
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Journal Article
Interferons at age 50: past, current and future impact on biomedicine
Borden, Ernest C, Sen, Ganes C, Uze, Gilles, Silverman, Robert H, Ransohoff, Richard M, Foster, Graham R, Stark, George R
Published in Nature reviews. Drug discovery (01.12.2007)
Published in Nature reviews. Drug discovery (01.12.2007)
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Journal Article
The opposing effects of interferon-beta and oncostatin-M as regulators of cancer stem cell plasticity in triple-negative breast cancer
Doherty, Mary R, Parvani, Jenny G, Tamagno, Ilaria, Junk, Damian J, Bryson, Benjamin L, Cheon, Hyeon Joo, Stark, George R, Jackson, Mark W
Published in Breast cancer research : BCR (29.04.2019)
Published in Breast cancer research : BCR (29.04.2019)
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Journal Article
A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis
Wu, Ling, Chen, Xing, Zhao, Junjie, Martin, Bradley, Zepp, Jarod A, Ko, Jennifer S, Gu, Chunfang, Cai, Gang, Ouyang, Wenjun, Sen, Ganes, Stark, George R, Su, Bing, Vines, Charlotte M, Tournier, Cathy, Hamilton, Thomas A, Vidimos, Allison, Gastman, Brian, Liu, Caini, Li, Xiaoxia
Published in The Journal of experimental medicine (21.09.2015)
Published in The Journal of experimental medicine (21.09.2015)
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OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug
Banerjee, Shuvojit, Gusho, Elona, Gaughan, Christina, Dong, Beihua, Gu, Xiaorong, Holvey-Bates, Elise, Talukdar, Manisha, Li, Yize, Weiss, Susan R., Sicheri, Frank, Saunthararajah, Yogen, Stark, George R., Silverman, Robert H.
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2019)
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Journal Article
Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3
Guryanova, Olga A., Wu, Qiulian, Cheng, Lin, Lathia, Justin D., Huang, Zhi, Yang, Jinbo, MacSwords, Jennifer, Eyler, Christine E., McLendon, Roger E., Heddleston, John M., Shou, Weinian, Hambardzumyan, Dolores, Lee, Jeongwu, Hjelmeland, Anita B., Sloan, Andrew E., Bredel, Markus, Stark, George R., Rich, Jeremy N., Bao, Shideng
Published in Cancer cell (12.04.2011)
Published in Cancer cell (12.04.2011)
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Hyperammonemia in cirrhosis induces transcriptional regulation of myostatin by an NF-κB–mediated mechanism
Qiu, Jia, Thapaliya, Samjhana, Runkana, Ashok, Yu Yang, Tsien, Cynthia, Mohan, Maradumane L., Narayanan, Arvind, Eghtesad, Bijan, Mozdziak, Paul E., McDonald, Christine, Stark, George R., Welle, Stephen, Prasad, Sathyamangla V. Naga, Dasarathy, Srinivasan
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2013)
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Journal Article
Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes
Yang, Jinbo, Huang, Jing, Dasgupta, Maupali, Sears, Nathan, Miyagi, Masaru, Wang, Benlian, Chance, Mark R., Chen, Xing, Du, Yuping, Wang, Yuxin, An, Lizhe, Wang, Qin, Lu, Tao, Zhang, Xiaodong, Wang, Zhenghe, Stark, George R.
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2010)
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Journal Article
Regulation of NF-κB by NSD1/FBXL11-dependent reversible lysine methylation of p65
Lu, Tao, Jackson, Mark W, Wang, Benlian, Yang, Maojing, Chance, Mark R, Miyagi, Masaru, Gudkov, Andrei V, Stark, George R
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2010)
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