Identification and characterization of pseudoirreversible nonpeptide antagonists of the neuropeptide Y Y 5 receptor and development of a novel Y 5-selective radioligand
Mullins, Deborra, Adham, Nika, Hesk, David, Wu, Yusheng, Kelly, Joseph, Huang, Ying, Guzzi, Mario, Zhang, Xiaoping, McCombie, Stuart, Stamford, Andrew, Parker, Eric
Published in European journal of pharmacology (28.12.2008)
Published in European journal of pharmacology (28.12.2008)
Get full text
Journal Article
O1–11–02: Kinetics of CNS APP metabolites in the presence of a BACE1 inhibitor in a non‐human primate model
Dobrowolska, Justyna, Michener, Maria, Wu, Guoxin, Patterson, Bruce, Chott, Robert, Ovod, Vitaliy, Pyatkivskyy, Yuriy, Wildsmith, Kristin, Kasten, Tom, Mathers, Parker, Dancho, Mandy, Lennox, Christina, Smith, Brad, Gilberto, David, McLoughlin, Debra, Holder, Dan, Stamford, Andrew, Yarasheski, Kevin, Kennedy, Matthew, Savage, Mary, Bateman, Randall
Published in Alzheimer's & dementia (01.07.2013)
Published in Alzheimer's & dementia (01.07.2013)
Get full text
Journal Article
Kinetics of CNS APP metabolites in the presence of a BACE1 inhibitor in a non-human primate model
Dobrowolska, Justyna, Michener, Maria, Wu, Guoxin, Patterson, Bruce, Chott, Robert, Ovod, Vitaliy, Pyatkivskyy, Yuriy, Wildsmith, Kristin, Kasten, Tom, Mathers, Parker, Dancho, Mandy, Lennox, Christina, Smith, Brad, Gilberto, David, McLoughlin, Debra, Holder, Dan, Stamford, Andrew, Yarasheski, Kevin, Kennedy, Matthew, Savage, Mary, Bateman, Randall
Published in Alzheimer's & dementia (01.07.2013)
Published in Alzheimer's & dementia (01.07.2013)
Get full text
Journal Article
Effect of a novel BACE inhibitor in the cisterna magna ported conscious rhesus monkey model
Michener, Maria, Wu, Guoxin, Kennedy, Matthew, Cumming, Jared, Dancho, Mandy, Korn, Rachel, Lennox, Christina, Suchecki, Izabela, Gilberto, David, Hershey, James, McLoughlin, Debra, Sun, Zhong-Yue, Zhu, Zhaoning, Stamford, Andrew, Parker, Eric, Savage, Mary
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
Get full text
Journal Article
P1‐233: Effect of a novel BACE inhibitor in the cisterna magna ported conscious rhesus monkey model
Michener, Maria, Wu, Guoxin, Kennedy, Matthew, Cumming, Jared, Dancho, Mandy, Korn, Rachel, Lennox, Christina, Suchecki, Izabela, Gilberto, David, Hershey, James, McLoughlin, Debra, Sun, Zhong‐Yue, Zhu, Zhaoning, Stamford, Andrew, Parker, Eric, Savage, Mary
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
Get full text
Journal Article
P1‐232: Chronic BACE inhibition halts further age‐related increases in brain Aß and amyloid plaques in aged TgCRND8 mice with established plaques
Hyde, Lynn, Cantu, Cinzia, Werner, Bonnie, Chen, Xia, Sondey, Marie, Chen, Maxine, Weig, Blair, LaShomb, Abigail, Lu, Sherry, Hodgson, Robert, Scott, Jack, Cumming, Jared, Stamford, Andrew, Parker, Eric, Kennedy, Matthew
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
Get full text
Journal Article
Chronic BACE inhibition halts further age-related increases in brain Aß and amyloid plaques in aged TgCRND8 mice with established plaques
Hyde, Lynn, Cantu, Cinzia, Werner, Bonnie, Chen, Xia, Sondey, Marie, Chen, Maxine, Weig, Blair, LaShomb, Abigail, Lu, Sherry, Hodgson, Robert, Scott, Jack, Cumming, Jared, Stamford, Andrew, Parker, Eric, Kennedy, Matthew
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
Get full text
Journal Article
Preladenant, a selective A sub(2A) receptor antagonist, is active in primate models of movement disorders
Hodgson, Robert A, Bedard, Paul J, Varty, Geoffrey B, Kazdoba, Tatiana M, Di Paolo, Therese, Grzelak, Michael E, Pond, Annamarie J, HadjTahar, Abdallah, Belanger, Nancy, Gregoire, Laurent, Dare, Aurelie, Neustadt, Bernard R, Stamford, Andrew W, Hunter, John C
Published in Experimental neurology (01.10.2010)
Published in Experimental neurology (01.10.2010)
Get full text
Journal Article
Identification and characterization of pseudoirreversible nonpeptide antagonists of the neuropeptide Y Y5 receptor and development of a novel Y5-selective radioligand
MULLINS, Deborra, ADHAM, Nika, PARKER, Eric, HESK, David, YUSHENG WU, KELLY, Joseph, YING HUANG, GUZZI, Mario, XIAOPING ZHANG, MCCOMBIE, Stuart, STAMFORD, Andrew
Published in European journal of pharmacology (28.12.2008)
Published in European journal of pharmacology (28.12.2008)
Get full text
Journal Article
IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE
CUMMING JARED N, STAMFORD ANDREW W, LI GUOQING, GILBERT ERIC J, SCOTT JACK D, MISIASZEK JEFFREY A, ISERLOH ULRICH
Year of Publication 10.08.2016
Get full text
Year of Publication 10.08.2016
Patent
A2A AMINOPYRAZINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES
KUANG RONGZE, WANG HONGWU, ZHOU GANG, TING PAULINE, ALI AMJAD, DENG QIAOLIN, BERLIN MICHAEL, STAMFORD ANDREW, KIM DAVID, LIM YEON HEE, YU YOUNONG, WU HEPING
Year of Publication 17.07.2017
Get full text
Year of Publication 17.07.2017
Patent
SUBSTITUTED QUINOLIZINE DERIVATIVES USEFUL AS HIV INTEGRASE INHIBITORS
WADDELL SHERMAN TIM, COLEMAN PAUL J, WAI JOHN S, SANDERS JOHN M, FERGUSON RONALD, YU TAO, ZHANG YONGLIAN, STAMFORD ANDREW
Year of Publication 31.05.2016
Get full text
Year of Publication 31.05.2016
Patent
Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel [mu]M Leads for the Development of nM BACE-1 ([beta]-Site APP Cleaving Enzyme 1) Inhibitors
Wang, Yu-Sen, Strickland, Corey, Voigt, Johannes H., Kennedy, Matthew E., Beyer, Brian M., Senior, Mary M., Smith, Elizabeth M., Nechuta, Terry L., Madison, Vincent S., Czarniecki, Michael, McKittrick, Brian A., Stamford, Andrew W., Parker, Eric M., Hunter, John C., Greenlee, William J., Wyss, Daniel F.
Published in Journal of medicinal chemistry (18.10.2010)
Published in Journal of medicinal chemistry (18.10.2010)
Get full text
Journal Article
Preladenant, a selective A 2A receptor antagonist, is active in primate models of movement disorders
Hodgson, Robert A., Bedard, Paul J., Varty, Geoffrey B., Kazdoba, Tatiana M., Di Paolo, Therese, Grzelak, Michael E., Pond, Annamarie J., HadjTahar, Abdallah, Belanger, Nancy, Gregoire, Laurent, Dare, Aurelie, Neustadt, Bernard R., Stamford, Andrew W., Hunter, John C.
Published in Experimental neurology (2010)
Published in Experimental neurology (2010)
Get full text
Journal Article
Identification and characterization of pseudoirreversible nonpeptide antagonists of the neuropeptide Y Y sub(5) receptor and development of a novel Y sub(5)-selective radioligand
Mullins, Deborra, Adham, Nika, Hesk, David, Wu, Yusheng, Kelly, Joseph, Huang, Ying, Guzzi, Mario, Zhang, Xiaoping, McCombie, Stuart, Stamford, Andrew, Parker, Eric
Published in European journal of pharmacology (01.12.2008)
Published in European journal of pharmacology (01.12.2008)
Get full text
Journal Article
Diaryl piperidines as CB sub(1) receptor antagonists
Scott, Jack D, Li, Sarah W, Wang, Hongwu, Xia, Yan, Jayne, Charles L, Miller, Michael W, Duffy, Ruth A, Boykow, George C, Kowalski, Timothy J, Spar, Brian D, Stamford, Andrew W, Chackalamannil, Samuel, Lachowicz, Jean E, Greenlee, William J
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Get full text
Journal Article
Diaryl piperidines as CB 1 receptor antagonists
Scott, Jack D., Li, Sarah W., Wang, Hongwu, Xia, Yan, Jayne, Charles L., Miller, Michael W., Duffy, Ruth A., Boykow, George C., Kowalski, Timothy J., Spar, Brian D., Stamford, Andrew W., Chackalamannil, Samuel, Lachowicz, Jean E., Greenlee, William J.
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
Get full text
Journal Article
TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS WITH INHIBITORS OF BET FAMILY BDII BROMODOMAIN
BARSOTTI, Anthony, STAMFORD, Andrew, SHIAU, Andrew, DAVIS, Robert, KAHRAMAN, Mehmet
Year of Publication 13.06.2024
Get full text
Year of Publication 13.06.2024
Patent
TREATMENT OF GRAFT-VERSUS-HOST DISEASE WITH INHIBITORS OF BET FAMILY BDII BROMODOMAIN
BARSOTTI, Anthony, ZHANG, Zhuming, STAMFORD, Andrew, SHIAU, Andrew, KAHRAMAN, Mehmet
Year of Publication 13.06.2024
Get full text
Year of Publication 13.06.2024
Patent
P3‐272: Pharmacological characterization of novel iminoheterocyclic BACE1 inhibitors for the treatment of Alzheimer's disease
Kennedy, Matthew E., Chen, Xia, Kuvelkar, Reshma, Cumming, Jared, Iserloh, Ulrich, McKittrick, Brian, Pan, Janping, Smith, Elizabeth, Sun, Zhong-Yue, Stamford, Andrew, Zhu, Zhaoning, Beyer, Brian, Strickland, Corey, Voigt, Johannes, Wang, Yu-Sen, Wyss, Daniel, Parker, Eric M.
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
Get full text
Journal Article