Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core
Borst, Andrew J, Weidle, Connor E, Gray, Matthew D, Frenz, Brandon, Snijder, Joost, Joyce, M Gordon, Georgiev, Ivelin S, Stewart-Jones, Guillaume Be, Kwong, Peter D, McGuire, Andrew T, DiMaio, Frank, Stamatatos, Leonidas, Pancera, Marie, Veesler, David
Published in eLife (07.11.2018)
Published in eLife (07.11.2018)
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Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein
Klein, Florian, Gaebler, Christian, Mouquet, Hugo, Sather, D Noah, Lehmann, Clara, Scheid, Johannes F, Kraft, Zane, Liu, Yan, Pietzsch, John, Hurley, Arlene, Poignard, Pascal, Feizi, Ten, Morris, Lynn, Walker, Bruce D, Fätkenheuer, Gerd, Seaman, Michael S, Stamatatos, Leonidas, Nussenzweig, Michel C
Published in The Journal of experimental medicine (30.07.2012)
Published in The Journal of experimental medicine (30.07.2012)
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Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier
Bonsignori, Mattia, Scott, Eric, Wiehe, Kevin, Easterhoff, David, Alam, S. Munir, Hwang, Kwan-Ki, Cooper, Melissa, Xia, Shi-Mao, Zhang, Ruijun, Montefiori, David C., Henderson, Rory, Nie, Xiaoyan, Kelsoe, Garnett, Moody, M. Anthony, Chen, Xuejun, Joyce, M. Gordon, Kwong, Peter D., Connors, Mark, Mascola, John R., McGuire, Andrew T., Stamatatos, Leonidas, Medina-Ramírez, Max, Sanders, Rogier W., Saunders, Kevin O., Kepler, Thomas B., Haynes, Barton F.
Published in Immunity (Cambridge, Mass.) (18.12.2018)
Published in Immunity (Cambridge, Mass.) (18.12.2018)
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HIV-1 single-stranded RNA induces CXCL13 secretion in human monocytes via TLR7 activation and plasmacytoid dendritic cell-derived type I IFN
Cohen, Kristen W, Dugast, Anne-Sophie, Alter, Galit, McElrath, M Juliana, Stamatatos, Leonidas
Published in The Journal of immunology (1950) (15.03.2015)
Published in The Journal of immunology (1950) (15.03.2015)
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Molecular signatures of hemagglutinin stem-directed heterosubtypic human neutralizing antibodies against influenza A viruses
Avnir, Yuval, Tallarico, Aimee S, Zhu, Quan, Bennett, Andrew S, Connelly, Gene, Sheehan, Jared, Sui, Jianhua, Fahmy, Amr, Huang, Chiung-yu, Cadwell, Greg, Bankston, Laurie A, McGuire, Andrew T, Stamatatos, Leonidas, Wagner, Gerhard, Liddington, Robert C, Marasco, Wayne A
Published in PLoS pathogens (01.05.2014)
Published in PLoS pathogens (01.05.2014)
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Human Immunodeficiency Virus Type 1 env Clones from Acute and Early Subtype B Infections for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies
Li, Ming, Gao, Feng, Mascola, John R, Stamatatos, Leonidas, Polonis, Victoria R, Koutsoukos, Marguerite, Voss, Gerald, Goepfert, Paul, Gilbert, Peter, Greene, Kelli M, Bilska, Miroslawa, Kothe, Denise L, Salazar-Gonzalez, Jesus F, Wei, Xiping, Decker, Julie M, Hahn, Beatrice H, Montefiori, David C
Published in Journal of Virology (01.08.2005)
Published in Journal of Virology (01.08.2005)
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Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope
Correia, Bruno E., Ban, Yih-En Andrew, Holmes, Margaret A., Xu, Hengyu, Ellingson, Katharine, Kraft, Zane, Carrico, Chris, Boni, Erica, Sather, D. Noah, Zenobia, Camille, Burke, Katherine Y., Bradley-Hewitt, Tyler, Bruhn-Johannsen, Jessica F., Kalyuzhniy, Oleksandr, Baker, David, Strong, Roland K., Stamatatos, Leonidas, Schief, William R.
Published in Structure (London) (08.09.2010)
Published in Structure (London) (08.09.2010)
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Antibody Binding to SARS-CoV-2 S Glycoprotein Correlates with but Does Not Predict Neutralization
Ding, Shilei, Laumaea, Annemarie, Benlarbi, Mehdi, Beaudoin-Bussières, Guillaume, Gasser, Romain, Medjahed, Halima, Pancera, Marie, Stamatatos, Leonidas, McGuire, Andrew T, Bazin, Renée, Finzi, Andrés
Published in Viruses (26.10.2020)
Published in Viruses (26.10.2020)
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HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies
LaBranche, Celia C, McGuire, Andrew T, Gray, Matthew D, Behrens, Shay, Kwong, Peter D, Chen, Xuejun, Zhou, Tongqing, Sattentau, Quentin J, Peacock, James, Eaton, Amanda, Greene, Kelli, Gao, Hongmei, Tang, Haili, Perez, Lautaro G, Chen, Xuejun, Saunders, Kevin O, Kwong, Peter D, Mascola, John R, Haynes, Barton F, Stamatatos, Leonidas, Montefiori, David C
Published in PLoS pathogens (05.11.2018)
Published in PLoS pathogens (05.11.2018)
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Journal Article
Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization
Parks, K. Rachael, MacCamy, Anna J., Trichka, Josephine, Gray, Matthew, Weidle, Connor, Borst, Andrew J., Khechaduri, Arineh, Takushi, Brittany, Agrawal, Parul, Guenaga, Javier, Wyatt, Richard T., Coler, Rhea, Seaman, Michael, LaBranche, Celia, Montefiori, David C., Veesler, David, Pancera, Marie, McGuire, Andrew, Stamatatos, Leonidas
Published in Cell reports (Cambridge) (03.12.2019)
Published in Cell reports (Cambridge) (03.12.2019)
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Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response
Bale, Shridhar, Yang, Lifei, Alirezaei, Mehrdad, Wilson, Richard, Ota, Takayuki, Doyle, Esmeralda D, Cottrell, Christopher A, Guenaga, Javier, Tran, Karen, Li, Wenjuan, Stamatatos, Leonidas, Nemazee, David, Ward, Andrew B, Wyatt, Richard T
Published in Frontiers in immunology (22.05.2023)
Published in Frontiers in immunology (22.05.2023)
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Sequential Immunization with a Subtype B HIV-1 Envelope Quasispecies Partially Mimics the In Vivo Development of Neutralizing Antibodies
MALHERBE, Delphine C, DORIA-ROSE, Nicole A, BARNETT, Susan, STAMATATOS, Leonidas, HAIGWOOD, Nancy L, MISHER, Lynda, BECKETT, Travis, BLAY PURYEAR, Wendy, SCHUMAN, Jason T, KRAFT, Zane, O'MALLEY, Jean, MORI, Motomi, SRIVASTAVA, Indresh
Published in Journal of Virology (01.06.2011)
Published in Journal of Virology (01.06.2011)
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Tracking SARS-CoV-2 Spike Protein Mutations in the United States (January 2020-March 2021) Using a Statistical Learning Strategy
Zhao, Lue Ping, Lybrand, Terry P, Gilbert, Peter B, Hawn, Thomas R, Schiffer, Joshua T, Stamatatos, Leonidas, Payne, Thomas H, Carpp, Lindsay N, Geraghty, Daniel E, Jerome, Keith R
Published in Viruses (21.12.2021)
Published in Viruses (21.12.2021)
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Journal Article
Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors
Yacoob, Christina, Pancera, Marie, Vigdorovich, Vladimir, Oliver, Brian G., Glenn, Jolene A., Feng, Junli, Sather, D. Noah, McGuire, Andrew T., Stamatatos, Leonidas
Published in Cell reports (Cambridge) (01.11.2016)
Published in Cell reports (Cambridge) (01.11.2016)
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The deficiency in Th2-like Tfh cells affects the maturation and quality of HIV-specific B cell response in viremic infection
Noto, Alessandra, Suffiotti, Madeleine, Joo, Victor, Mancarella, Antonio, Procopio, Francesco A., Cavet, Guy, Leung, Yvonne, Corpataux, Jean-Marc, Cavassini, Matthias, Riva, Agostino, Stamatatos, Leonidas, Gottardo, Raphael, McDermott, Adrian B., Koup, Richard A., Fenwick, Craig, Perreau, Matthieu, Pantaleo, Giuseppe
Published in Frontiers in immunology (24.08.2022)
Published in Frontiers in immunology (24.08.2022)
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Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies
Seydoux, Emilie, Wan, Yu-Hsin, Feng, Junli, Wall, Abigail, Aljedani, Safia, Homad, Leah J., MacCamy, Anna J., Weidle, Connor, Gray, Matthew D., Brumage, Lauren, Taylor, Justin J., Pancera, Marie, Stamatatos, Leonidas, McGuire, Andrew T.
Published in Cell reports (Cambridge) (04.05.2021)
Published in Cell reports (Cambridge) (04.05.2021)
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B cell clonal lineage alterations upon recombinant HIV-1 envelope immunization of rhesus macaques
Yacoob, Christina, Lange, Miles Darnell, Cohen, Kristen, Lathia, Kanan, Feng, Junli, Glenn, Jolene, Carbonetti, Sara, Oliver, Brian, Vigdorovich, Vladimir, Sather, David Noah, Stamatatos, Leonidas
Published in PLoS pathogens (01.06.2018)
Published in PLoS pathogens (01.06.2018)
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Broadly Neutralizing Antibodies Developed by an HIV-Positive Elite Neutralizer Exact a Replication Fitness Cost on the Contemporaneous Virus
SATHER, D. Noah, CARBONETTI, Sara, KEHAYIA, Jenny, KRAFT, Zane, MIKELL, Iliyana, SCHEID, Johannes F, KLEIN, Florian, STAMATATOS, Leonidas
Published in Journal of Virology (01.12.2012)
Published in Journal of Virology (01.12.2012)
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