Design and synthesis of potent, isoxazole-containing renin inhibitors
Fournier, Pierre-André, Arbour, Mélissa, Cauchon, Elizabeth, Chen, Austin, Chefson, Amandine, Ducharme, Yves, Falgueyret, Jean-Pierre, Gagné, Sébastien, Grimm, Erich, Han, Yongxin, Houle, Robert, Lacombe, Patrick, Lévesque, Jean-François, MacDonald, Dwight, Mackay, Bruce, McKay, Dan, Percival, M. David, Ramtohul, Yeeman, St-Jacques, René, Toulmond, Sylvie
Published in Bioorganic & medicinal chemistry letters (15.04.2012)
Published in Bioorganic & medicinal chemistry letters (15.04.2012)
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Cathepsin K null mice show reduced adiposity during the rapid accumulation of fat stores
Funicello, Marcella, Novelli, Michela, Ragni, Maurizio, Vottari, Teresa, Cocuzza, Cesare, Soriano-Lopez, Joaquin, Chiellini, Chiara, Boschi, Federico, Marzola, Pasquina, Masiello, Pellegrino, Saftig, Paul, Santini, Ferruccio, St-Jacques, Rene, Desmarais, Sylvie, Morin, Nicolas, Mancini, Joseph, Percival, M David, Pinchera, Aldo, Maffei, Margherita
Published in PloS one (01.08.2007)
Published in PloS one (01.08.2007)
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3,4-Diarylpiperidines as potent renin inhibitors
Lacombe, Patrick, Arbour, Mélissa, Aspiotis, Renée, Cauchon, Elizabeth, Chen, Austin, Dubé, Daniel, Falgueyret, Jean-Pierre, Fournier, Pierre-André, Gallant, Michel, Grimm, Erich, Han, Yongxin, Juteau, Hélène, Liu, Suzanna, Mellon, Christophe, Ramtohul, Yeeman, Simard, Daniel, St-Jacques, René, Tsui, Gavin Chit
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
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Journal Article
Renin inhibitors for the treatment of hypertension: Design and optimization of a novel series of pyridone-substituted piperidines
Chen, Austin, Campeau, Louis-Charles, Cauchon, Elizabeth, Chefson, Amandine, Ducharme, Yves, Dubé, Daniel, Falgueyret, Jean-Pierre, Fournier, Pierre-André, Gagné, Sébastien, Grimm, Erich, Han, Yongxin, Houle, Robert, Huang, Jing-Qi, Lacombe, Patrick, Laliberté, Sébastien, Lévesque, Jean-François, Liu, Susana, MacDonald, Dwight, Mackay, Bruce, McKay, Dan, Percival, M. David, Regan, Chris, Regan, Hillary, St-Jacques, René, Toulmond, Sylvie
Published in Bioorganic & medicinal chemistry letters (01.07.2011)
Published in Bioorganic & medicinal chemistry letters (01.07.2011)
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Renin inhibitors for the treatment of hypertension: Design and optimization of a novel series of tertiary alcohol-bearing piperidines
Chen, Austin, Cauchon, Elizabeth, Chefson, Amandine, Dolman, Sarah, Ducharme, Yves, Dubé, Daniel, Falgueyret, Jean-Pierre, Fournier, Pierre-André, Gagné, Sébastien, Gallant, Michel, Grimm, Erich, Han, Yongxin, Houle, Robert, Huang, Jing-Qi, Hughes, Gregory, Jûteau, Hélène, Lacombe, Patrick, Lauzon, Sophie, Lévesque, Jean-François, Liu, Susana, MacDonald, Dwight, Mackay, Bruce, McKay, Dan, Percival, M. David, St-Jacques, René, Toulmond, Sylvie
Published in Bioorganic & medicinal chemistry letters (01.07.2011)
Published in Bioorganic & medicinal chemistry letters (01.07.2011)
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Pharmacological and genetic evidence that cathepsin B is not the physiological activator of rodent prorenin
Percival, M. David, Toulmond, Sylvie, Coulombe, Nathalie, Cromlish, Wanda, Desmarais, Sylvie, Liu, Susana, St-Jacques, René, Gauthier, Jacques Yves, Fournier, Jean-Francois
Published in Biological chemistry (01.12.2010)
Published in Biological chemistry (01.12.2010)
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Characterization of a stable, hypertensive rat model suitable for the consecutive evaluation of human renin inhibitors
St-Jacques, René, Toulmond, Sylvie, Auger, Anick, Binkert, Christoph, Cromlish, Wanda, Fischli, Walter, Harris, Jennifer, Hess, Patrick, Jie Lan, Liu, Susana, Riendeau, Denis, Steiner, Beat, Percival, M David
Published in Journal of the renin-angiotensin-aldosterone system (01.09.2011)
Published in Journal of the renin-angiotensin-aldosterone system (01.09.2011)
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The geminal dimethyl analogue of Flurbiprofen as a novel Aβ42 inhibitor and potential Alzheimer's disease modifying agent
STOCK, Nicholas, MUNOZ, Benito, ST-JACQUES, René, PRASIT, Peppi, WRIGLEY, Jonathan D. J, SHEARMAN, Mark S, BEHER, Dirk, PEACHEY, James, WILLIAMSON, Toni L, BAIN, Gretchen, WEICHAO CHEN, XIAOHUI JIANG
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
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Journal Article
Characterization of hypoxia-induced ventilatory depression in newborn piglets
St-Jacques, Rene, Filiano, James J., Darnall, Robert A., St-John, Walter M.
Published in Experimental physiology (01.07.2003)
Published in Experimental physiology (01.07.2003)
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The geminal dimethyl analogue of Flurbiprofen as a novel Aβ 42 inhibitor and potential Alzheimer’s disease modifying agent
Stock, Nicholas, Munoz, Benito, Wrigley, Jonathan D.J., Shearman, Mark S., Beher, Dirk, Peachey, James, Williamson, Toni L., Bain, Gretchen, Chen, Weichao, Jiang, Xiaohui, St-Jacques, René, Prasit, Peppi
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
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Journal Article
The geminal dimethyl analogue of Flurbiprofen as a novel Abeta42 inhibitor and potential Alzheimer's disease modifying agent
Stock, Nicholas, Munoz, Benito, Wrigley, Jonathan D J, Shearman, Mark S, Beher, Dirk, Peachey, James, Williamson, Toni L, Bain, Gretchen, Chen, Weichao, Jiang, Xiaohui, St-Jacques, René, Prasit, Peppi
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
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Published in Bioorganic & medicinal chemistry letters (15.04.2006)
Journal Article
Modulation of hypoxic depressions of ventilatory activity in the newborn piglet by mesencephalic mechanisms
St.-John, Walter M., St. Jacques, René, Li, Aihua, Darnall, Robert A.
Published in Brain research (20.02.1999)
Published in Brain research (20.02.1999)
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Journal Article
The geminal dimethyl analogue of Flurbiprofen as a novel A beta sub(42) inhibitor and potential Alzheimer's disease modifying agent
Stock, Nicholas, Munoz, Benito, Wrigley, Jonathan DJ, Shearman, Mark S, Beher, Dirk, Peachey, James, Williamson, Toni L, Bain, Gretchen, Chen, Weichao, Jiang, Xiaohui, St-Jacques, Rene, Prasit, Peppi
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
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Journal Article
Tropfenbewässerungsvorrichtung mit Abzweigverbindungen
GARCIA, JEAN, F-38850 CHARAVINES, FR, QUIGNARD, RENE JACQUES, F-38120 ST. EGREVE, FR
Year of Publication 10.03.1994
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Year of Publication 10.03.1994
Patent
TROPFENBEWAESSERUNGSVORRICHTUNG MIT ABZWEIGVERBINDUNGEN
GARCIA, JEAN, F-38850 CHARAVINES, FR, QUIGNARD, RENE JACQUES, F-38120 ST. EGREVE, FR
Year of Publication 17.10.1991
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Year of Publication 17.10.1991
Patent