Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists
Evans, B. E, Rittle, K. E, Bock, M. G, DiPardo, R. M, Freidinger, R. M, Whitter, W. L, Lundell, G. F, Veber, D. F, Anderson, P. S, Chang, R. S. L, Lotti, V. J, Cerino, D. J, Chen, T. B, Kling, P. J, Kunkel, K. A, Springer, J. P, Hirshfield, J
Published in Journal of medicinal chemistry (01.12.1988)
Published in Journal of medicinal chemistry (01.12.1988)
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Structure of Inositol Monophosphatase, the Putative Target of Lithium Therapy
Bone, Roger, Springer, James P., Atack, John R.
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1992)
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1992)
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Decreased sensitivity in the membranous urethra after orthotopic ileal bladder substitute
Hugonnet, C L, Danuser, H, Springer, J P, Studer, U E
Published in The Journal of urology (01.02.1999)
Published in The Journal of urology (01.02.1999)
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Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution
NAVIA, M. A, MCKEEVER, B. M, SPRINGER, J. P, TSAU-YEN LIN, WILLIAMS, H. R, FLUDER, E. M, DORN, C. P, HOOGSTEEN, K
Published in Proceedings of the National Academy of Sciences - PNAS (01.01.1989)
Published in Proceedings of the National Academy of Sciences - PNAS (01.01.1989)
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Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-A resolution
FITZGERALD, P. M. D, MCKEEVER, B. M, VANMIDDLESWORTH, J. F, SPRINGER, J. P, HEIMBACH, J. C, CHIH-TAI LEU, HERBER, W. K, DIXON, R. A. F, DARKE, P. L
Published in The Journal of biological chemistry (25.08.1990)
Published in The Journal of biological chemistry (25.08.1990)
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Central muscarinic inhibition of lower urinary tract nociception
Thor, Karl B, Muhlhauser, Mark A, Sauerberg, Per, Shannon, Harlan, Springer, Johannes P
Published in Brain research (07.07.2000)
Published in Brain research (07.07.2000)
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FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818
Becker, J.W., Rotonda, J., McKeever, B.M., Chan, H.K., Marcy, A.I., Wiederrecht, G., Hermes, J.D., Springer, J.P.
Published in The Journal of biological chemistry (25.05.1993)
Published in The Journal of biological chemistry (25.05.1993)
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Extrinsic innervation of the cat prostate gland: a combined tracing and immunohistochemical study
Danuser, H, Springer, J P, Katofiasc, M A, Thor, K B
Published in The Journal of urology (01.03.1997)
Published in The Journal of urology (01.03.1997)
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Homoallylic chiral induction in the synthesis of 2,4-disubstituted tetrahydrofurans by iodoetherification. Synthetic scope and chiral induction mechanism
Labelle, Marc, Morton, H. E, Guindon, Y, Springer, J. P
Published in Journal of the American Chemical Society (01.07.1988)
Published in Journal of the American Chemical Society (01.07.1988)
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Thienothiopyran-2-sulfonamides: novel topically active carbonic anhydrase inhibitors for the treatment of glaucoma
Baldwin, John J, Ponticello, Gerald S, Anderson, Paul S, Christy, Marcia E, Murcko, Mark A, Randall, William C, Schwam, Harvey, Sugrue, Michael F, Gautheron, Pierre
Published in Journal of medicinal chemistry (01.12.1989)
Published in Journal of medicinal chemistry (01.12.1989)
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Journal Article
Secondary structure and zinc ligation of human recombinant short-form stromelysin by multidimensional heteronuclear NMR
Gooley, Paul R., Johnson, Bruce A., Marcy, Alice I., Cuca, Gregory C., Salowe, Scott P., Hagmann, William K., Esser, Craig K., Springer, James P.
Published in Biochemistry (Easton) (07.12.1993)
Published in Biochemistry (Easton) (07.12.1993)
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Crystallization of the aspartylprotease from the human immunodeficiency virus, HIV-1
McKeever, B M, Navia, M A, Fitzgerald, P M D, Springer, J P, Leu, C T, Heimbach, J C, Herbert, W K, Sigal, I S, Darke, P L
Published in The Journal of biological chemistry (05.02.1989)
Published in The Journal of biological chemistry (05.02.1989)
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Journal Article
Phosphinic acid inhibitors of D-alanyl-D-alanine ligase
Parsons, William H, Patchett, Arthur A, Bull, Herbert G, Schoen, William R, Taub, David, Davidson, Jacqueline, Combs, Patricia L, Springer, James P, Gadebusch, Hans
Published in Journal of medicinal chemistry (01.09.1988)
Published in Journal of medicinal chemistry (01.09.1988)
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Journal Article
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
Navia, M A, Fitzgerald, P M, McKeever, B M, Leu, C T, Heimbach, J C, Herber, W K, Sigal, I S, Darke, P L, Springer, J P
Published in Nature (London) (16.02.1989)
Published in Nature (London) (16.02.1989)
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Inhibition of the Mammalian β-lactamase renal dipeptidase (dehydropeptidase-I) by (Z)-2-(acylamino)-3-substituted-propenoic acids
GRAHAM, D. W, ASHTON, W. T, BARASH, L, BROWN, J. E, BROWN, R. D, CANNING, L. F, CHEN, A, SPRINGER, J. P, ROGERS, E. F
Published in Journal of medicinal chemistry (01.06.1987)
Published in Journal of medicinal chemistry (01.06.1987)
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Bioactive conformation of 1-arylpiperazines at central serotonin receptors
Huff, Joel R, King, Stella W, Saari, Walfred S, Springer, J. P, Martin, Gregory E, Williams, Michael
Published in Journal of medicinal chemistry (01.07.1985)
Published in Journal of medicinal chemistry (01.07.1985)
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Conformationally restricted inhibitors of angiotensin-converting enzyme. Synthesis and computations
Thorsett, Eugene D, Harris, Elbert E, Aster, Susan D, Peterson, Elwood R, Snyder, James P, Springer, James P, Hirshfield, Jordan, Tristram, Edward W, Patchett, Arthur A
Published in Journal of medicinal chemistry (01.02.1986)
Published in Journal of medicinal chemistry (01.02.1986)
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