TIGIT, the Next Step Towards Successful Combination Immune Checkpoint Therapy in Cancer
Ge, Zhouhong, Peppelenbosch, Maikel P, Sprengers, Dave, Kwekkeboom, Jaap
Published in Frontiers in immunology (22.07.2021)
Published in Frontiers in immunology (22.07.2021)
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Journal Article
LGR5 marks targetable tumor-initiating cells in mouse liver cancer
Cao, Wanlu, Li, Meng, Liu, Jiaye, Zhang, Shaoshi, Noordam, Lisanne, Verstegen, Monique M A, Wang, Ling, Ma, Buyun, Li, Shan, Wang, Wenshi, Bolkestein, Michiel, Doukas, Michael, Chen, Kan, Ma, Zhongren, Bruno, Marco, Sprengers, Dave, Kwekkeboom, Jaap, van der Laan, Luc J W, Smits, Ron, Peppelenbosch, Maikel P, Pan, Qiuwei
Published in Nature communications (23.04.2020)
Published in Nature communications (23.04.2020)
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Journal Article
Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules
Zhou, Guoying, Sprengers, Dave, Mancham, Shanta, Erkens, Remco, Boor, Patrick P.C., van Beek, Adriaan A., Doukas, Michail, Noordam, Lisanne, Campos Carrascosa, Lucia, de Ruiter, Valeska, van Leeuwen, Roelof W.F., Polak, Wojciech G., de Jonge, Jeroen, Groot Koerkamp, Bas, van Rosmalen, Belle, van Gulik, Thomas M., Verheij, Joanne, IJzermans, Jan N.M., Bruno, Marco J., Kwekkeboom, Jaap
Published in Journal of hepatology (01.10.2019)
Published in Journal of hepatology (01.10.2019)
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Journal Article
Enrichment of the tumour immune microenvironment in patients with desmoplastic colorectal liver metastasis
Höppener, Diederik J, Nierop, Pieter M H, Hof, Joost, Sideras, Kostandinos, Zhou, Guoying, Visser, Lydia, Gouw, Annette S H, de Jong, Koert P, Sprengers, Dave, Kwekkeboom, Jaap, Vermeulen, Peter B, Grünhagen, Dirk J, Verhoef, Cornelis
Published in British journal of cancer (01.07.2020)
Published in British journal of cancer (01.07.2020)
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Modeling rotavirus infection and antiviral therapy using primary intestinal organoids
Yin, Yuebang, Bijvelds, Marcel, Dang, Wen, Xu, Lei, van der Eijk, Annemiek A., Knipping, Karen, Tuysuz, Nesrin, Dekkers, Johanna F., Wang, Yijin, de Jonge, Jeroen, Sprengers, Dave, van der Laan, Luc J.W., Beekman, Jeffrey M., ten Berge, Derk, Metselaar, Herold J., de Jonge, Hugo, Koopmans, Marion P.G., Peppelenbosch, Maikel P., Pan, Qiuwei
Published in Antiviral research (01.11.2015)
Published in Antiviral research (01.11.2015)
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Cryptogenic non-cirrhotic HCC: Clinical, prognostic and immunologic aspects of an emerging HCC etiology
Beudeker, Boris J B, Guha, Rael, Stoyanova, Kalina, IJzermans, Jan N M, de Man, Robert A, Sprengers, Dave, Boonstra, Andre
Published in Scientific reports (21.02.2024)
Published in Scientific reports (21.02.2024)
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Journal Article
Engaging stimulatory immune checkpoint interactions in the tumour immune microenvironment of primary liver cancers - how to push the gas after having released the brake
Rakké, Yannick S, Buschow, Sonja I, IJzermans, Jan N M, Sprengers, Dave
Published in Frontiers in immunology (19.02.2024)
Published in Frontiers in immunology (19.02.2024)
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Journal Article
HHLA2 is expressed in pancreatic and ampullary cancers and increased expression is associated with better post-surgical prognosis
Boor, Patrick P C, Sideras, Kostandinos, Biermann, Katharina, Hosein Aziz, M, Levink, Iris J M, Mancham, Shanta, Erler, Nicole S, Tang, Xudong, van Eijck, Casper H, Bruno, Marco J, Sprengers, Dave, Zang, Xingxing, Kwekkeboom, Jaap
Published in British journal of cancer (01.04.2020)
Published in British journal of cancer (01.04.2020)
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Journal Article
Modeling liver cancer and therapy responsiveness using organoids derived from primary mouse liver tumors
Cao, Wanlu, Liu, Jiaye, Wang, Ling, Li, Meng, Verstegen, Monique M A, Yin, Yuebang, Ma, Buyun, Chen, Kan, Bolkestein, Michiel, Sprengers, Dave, van der Laan, Luc J W, Doukas, Michael, Kwekkeboom, Jaap, Smits, Ron, Peppelenbosch, Maikel P, Pan, Qiuwei
Published in Carcinogenesis (New York) (12.03.2019)
Published in Carcinogenesis (New York) (12.03.2019)
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Journal Article
PD-L1, Galectin-9 and CD8+ tumor-infiltrating lymphocytes are associated with survival in hepatocellular carcinoma
Sideras, Kostandinos, Biermann, Katharina, Verheij, Joanne, Takkenberg, Bart R., Mancham, Shanta, Hansen, Bettina E., Schutz, Hannah M., de Man, Robert A., Sprengers, Dave, Buschow, Sonja I., Verseput, Maddy C. M., Boor, Patrick P. C., Pan, Qiuwei, van Gulik, Thomas M., Terkivatan, Turkan, Ijzermans, Jan N. M., Beuers, Ulrich H. W., Sleijfer, Stefan, Bruno, Marco J., Kwekkeboom, Jaap
Published in Oncoimmunology (01.02.2017)
Published in Oncoimmunology (01.02.2017)
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Journal Article
Dynamics of Proliferative and Quiescent Stem Cells in Liver Homeostasis and Injury
Cao, Wanlu, Chen, Kan, Bolkestein, Michiel, Yin, Yuebang, Verstegen, Monique M.A., Bijvelds, Marcel J.C., Wang, Wenshi, Tuysuz, Nesrin, ten Berge, Derk, Sprengers, Dave, Metselaar, Herold J., van der Laan, Luc J.W., Kwekkeboom, Jaap, Smits, Ron, Peppelenbosch, Maikel P., Pan, Qiuwei
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2017)
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Journal Article
Blockade of LAG3 enhances responses of tumor-infiltrating T cells in mismatch repair-proficient liver metastases of colorectal cancer
Zhou, Guoying, Noordam, Lisanne, Sprengers, Dave, Doukas, Michail, Boor, Patrick P. C., van Beek, Adriaan A., Erkens, Remco, Mancham, Shanta, Grünhagen, Dirk, Menon, Anand G., Lange, Johan F., Burger, Pim J. W. A., Brandt, Alexandra, Galjart, Boris, Verhoef, Cornelis, Kwekkeboom, Jaap, Bruno, Marco J.
Published in Oncoimmunology (03.07.2018)
Published in Oncoimmunology (03.07.2018)
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The Yield of Routine Post-Operative Doppler Ultrasound to Detect Early Post-Liver Transplantation Vascular Complications
Minciuna, Iulia, den Hoed, Caroline, van der Meer, Adriaan J, Sonneveld, Milan J, Sprengers, Dave, de Knegt, Robert J, de Jonge, Jeroen, Maan, Raoel, Polak, Wojciech G, Darwish Murad, Sarwa
Published in Transplant international (29.11.2023)
Published in Transplant international (29.11.2023)
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Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth
Li, Meng, Wang, Ling, Wang, Yijin, Zhang, Shaoshi, Zhou, Guoying, Lieshout, Ruby, Ma, Buyun, Liu, Jiaye, Qu, Changbo, Verstegen, Monique M A, Sprengers, Dave, Kwekkeboom, Jaap, van der Laan, Luc J W, Cao, Wanlu, Peppelenbosch, Maikel P, Pan, Qiuwei
Published in Cells (Basel, Switzerland) (04.01.2020)
Published in Cells (Basel, Switzerland) (04.01.2020)
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Journal Article
External Validation of the RETREAT Score for Prediction of Hepatocellular Carcinoma Recurrence after Liver Transplantation
van Hooff, Maria C, Sonneveld, Milan J, Ijzermans, Jan N, Doukas, Michail, Sprengers, Dave, Metselaar, Herold J, den Hoed, Caroline M, de Man, Robert A
Published in Cancers (27.01.2022)
Published in Cancers (27.01.2022)
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Journal Article
Detection of oncogenic mutations in paired circulating tumor DNA and circulating tumor cells in patients with hepatocellular carcinoma
Ge, Zhouhong, Helmijr, Jean C.A., Jansen, Maurice P.H.M., Boor, Patrick P.C., Noordam, Lisanne, Peppelenbosch, Maikel, Kwekkeboom, Jaap, Kraan, Jaco, Sprengers, Dave
Published in Translational oncology (01.07.2021)
Published in Translational oncology (01.07.2021)
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Cancer Cell B7-H3 Expression Is More Prevalent in the Pancreato-Biliary Subtype of Ampullary Cancer Than in Pancreatic Cancer
Geerdes, Emma E, Sideras, Kostandinos, Aziz, M Hosein, van Eijck, Casper H, Bruno, Marco J, Sprengers, Dave, Boor, Patrick P C, Kwekkeboom, Jaap
Published in Frontiers in oncology (29.04.2021)
Published in Frontiers in oncology (29.04.2021)
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Distinct Antiviral Potency of Sofosbuvir against Hepatitis C and E Viruses
Wang, Wenshi, Hakim, Mohamad S, Nair, Vidya P, de Ruiter, Petra E, Huang, Fen, Sprengers, Dave, Van Der Laan, Luc J.W, Peppelenbosch, Maikel P, Surjit, Milan, Pan, Qiuwei
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2016)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2016)
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Journal Article
Systemic T-cell and humoral responses against cancer testis antigens in hepatocellular carcinoma patients
Noordam, Lisanne, de Beijer, Monique T.A., Mancham, Shanta, Vogler, Isabel, Boor, Patrick P.C., de Ruiter, Valeska, Luijten, Robbie, IJzermans, Jan N.M., Sahin, Ugur, Bruno, Marco J., Sprengers, Dave, Buschow, Sonja I., Kwekkeboom, Jaap
Published in Oncoimmunology (31.12.2022)
Published in Oncoimmunology (31.12.2022)
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