Study of key residues in MERS-CoV and SARS-CoV-2 main proteases for resistance against clinically applied inhibitors nirmatrelvir and ensitrelvir
Krismer, Laura, Schöppe, Helge, Rauch, Stefanie, Bante, David, Sprenger, Bernhard, Naschberger, Andreas, Costacurta, Francesco, Fürst, Anna, Sauerwein, Anna, Rupp, Bernhard, Kaserer, Teresa, von Laer, Dorothee, Heilmann, Emmanuel
Published in Npj Viruses (01.01.2024)
Published in Npj Viruses (01.01.2024)
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Efficient In Silico Saturation Mutagenesis of a Member of the Caspase Protease Family
Öhlknecht, Christoph, Katz, Sonja, Kröß, Christina, Sprenger, Bernhard, Engele, Petra, Schneider, Rainer, Oostenbrink, Chris
Published in Journal of chemical information and modeling (22.03.2021)
Published in Journal of chemical information and modeling (22.03.2021)
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Enhancing the promiscuity of a member of the Caspase protease family by rational design
Öhlknecht, Christoph, Petrov, Drazen, Engele, Petra, Kröß, Christina, Sprenger, Bernhard, Fischer, Andreas, Lingg, Nico, Schneider, Rainer, Oostenbrink, Chris
Published in Proteins, structure, function, and bioinformatics (01.10.2020)
Published in Proteins, structure, function, and bioinformatics (01.10.2020)
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PROFICS: A bacterial selection system for directed evolution of proteases
Kröß, Christina, Engele, Petra, Sprenger, Bernhard, Fischer, Andreas, Lingg, Nico, Baier, Magdalena, Öhlknecht, Christoph, Lier, Bettina, Oostenbrink, Chris, Cserjan-Puschmann, Monika, Striedner, Gerald, Jungbauer, Alois, Schneider, Rainer
Published in The Journal of biological chemistry (01.10.2021)
Published in The Journal of biological chemistry (01.10.2021)
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A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system
Costacurta, Francesco, Dodaro, Andrea, Bante, David, Schöppe, Helge, Peng, Ju-Yi, Sprenger, Bernhard, He, Xi, Moghadasi, Seyed Arad, Egger, Lisa Maria, Fleischmann, Jakob, Pavan, Matteo, Bassani, Davide, Menin, Silvia, Rauch, Stefanie, Krismer, Laura, Sauerwein, Anna, Heberle, Anne, Rabensteiner, Toni, Ho, Joses, Harris, Reuben S, Stefan, Eduard, Schneider, Rainer, Dunzendorfer-Matt, Theresia, Naschberger, Andreas, Wang, Dai, Kaserer, Teresa, Moro, Stefano, von Laer, Dorothee, Heilmann, Emmanuel
Published in PLoS pathogens (11.09.2024)
Published in PLoS pathogens (11.09.2024)
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Journal Article
A comprehensive study of SARS-CoV-2 main protease
Costacurta, Francesco, Dodaro, Andrea, Bante, David, Schöppe, Helge, Peng, Ju-Yi, Sprenger, Bernhard, He, Xi, Moghadasi, Seyed Arad, Egger, Lisa Maria, Fleischmann, Jakob, Pavan, Matteo, Bassani, Davide, Menin, Silvia, Rauch, Stefanie, Krismer, Laura, Sauerwein, Anna, Heberle, Anne, Rabensteiner, Toni, Ho, Joses, Harris, Reuben S, Stefan, Eduard, Schneider, Rainer, Dunzendorfer-Matt, Theresia, Naschberger, Andreas, Wang, Dai, Kaserer, Teresa, Moro, Stefano, von Laer, Dorothee, Heilmann, Emmanuel
Published in PLoS pathogens (11.09.2024)
Published in PLoS pathogens (11.09.2024)
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Highly specific SARS-CoV-2 main protease (Mpro) mutations against the clinical antiviral ensitrelvir selected in a safe, VSV-based system
Rauch, Stefanie, Costacurta, Francesco, Schöppe, Helge, Peng, Ju-Yi, Bante, David, Erisoez, Ela Emilie, Sprenger, Bernhard, He, Xi, Moghadasi, Seyed Arad, Krismer, Laura, Sauerwein, Anna, Heberle, Anne, Rabensteiner, Toni, Wang, Dai, Naschberger, Andreas, Dunzendorfer-Matt, Theresia, Kaserer, Teresa, von Laer, Dorothee, Heilmann, Emmanuel
Published in Antiviral research (01.11.2024)
Published in Antiviral research (01.11.2024)
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CASPON platform technology: Ultrafast circularly permuted caspase-2 cleaves tagged fusion proteins before all 20 natural amino acids at the N-terminus
Lingg, Nico, Kröß, Christina, Engele, Petra, Öhlknecht, Christoph, Köppl, Christoph, Fischer, Andreas, Lier, Bettina, Loibl, Julian, Sprenger, Bernhard, Liu, Jakob, Scheidl, Patrick, Berkemeyer, Matthias, Buchinger, Wolfgang, Brocard, Cécile, Striedner, Gerald, Oostenbrink, Chris, Schneider, Rainer, Jungbauer, Alois, Cserjan-Puschmann, Monika
Published in New biotechnology (25.11.2022)
Published in New biotechnology (25.11.2022)
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