NPM1-mutated acute myeloid leukemia: from bench to bedside
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Published in Blood (08.10.2020)
Published in Blood (08.10.2020)
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Mutant NPM1 Maintains the Leukemic State through HOX Expression
Brunetti, Lorenzo, Gundry, Michael C., Sorcini, Daniele, Guzman, Anna G., Huang, Yung-Hsin, Ramabadran, Raghav, Gionfriddo, Ilaria, Mezzasoma, Federica, Milano, Francesca, Nabet, Behnam, Buckley, Dennis L., Kornblau, Steven M., Lin, Charles Y., Sportoletti, Paolo, Martelli, Maria Paola, Falini, Brunangelo, Goodell, Margaret A.
Published in Cancer cell (10.09.2018)
Published in Cancer cell (10.09.2018)
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Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
Di Ianni, Mauro, Falzetti, Franca, Carotti, Alessandra, Terenzi, Adelmo, Castellino, Flora, Bonifacio, Elisabetta, Del Papa, Beatrice, Zei, Tiziana, Ostini, Roberta Iacucci, Cecchini, Debora, Aloisi, Teresa, Perruccio, Katia, Ruggeri, Loredana, Balucani, Chiara, Pierini, Antonio, Sportoletti, Paolo, Aristei, Cynthia, Falini, Brunangelo, Reisner, Yair, Velardi, Andrea, Aversa, Franco, Martelli, Massimo F.
Published in Blood (07.04.2011)
Published in Blood (07.04.2011)
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BRAF Mutations in Hairy-Cell Leukemia
Tiacci, Enrico, Trifonov, Vladimir, Schiavoni, Gianluca, Holmes, Antony, Kern, Wolfgang, Martelli, Maria Paola, Pucciarini, Alessandra, Bigerna, Barbara, Pacini, Roberta, Wells, Victoria A, Sportoletti, Paolo, Pettirossi, Valentina, Mannucci, Roberta, Elliott, Oliver, Liso, Arcangelo, Ambrosetti, Achille, Pulsoni, Alessandro, Forconi, Francesco, Trentin, Livio, Semenzato, Gianpietro, Inghirami, Giorgio, Capponi, Monia, Di Raimondo, Francesco, Patti, Caterina, Arcaini, Luca, Musto, Pellegrino, Pileri, Stefano, Haferlach, Claudia, Haferlach, Torsten, Schnittger, Susanne, Pizzolo, Giovanni, Foà, Robin, Farinelli, Laurent, Pasqualucci, Laura, Rabadan, Raul, Falini, Brunangelo
Published in The New England journal of medicine (16.06.2011)
Published in The New England journal of medicine (16.06.2011)
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Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells
Martelli, Maria Paola, Gionfriddo, Ilaria, Mezzasoma, Federica, Milano, Francesca, Pierangeli, Sara, Mulas, Floriana, Pacini, Roberta, Tabarrini, Alessia, Pettirossi, Valentina, Rossi, Roberta, Vetro, Calogero, Brunetti, Lorenzo, Sportoletti, Paolo, Tiacci, Enrico, Di Raimondo, Francesco, Falini, Brunangelo
Published in Blood (28.05.2015)
Published in Blood (28.05.2015)
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Nanotechnology Advances in the Detection and Treatment of Lymphoid Malignancies
Adamo, Francesco Maria, De Falco, Filomena, Dorillo, Erica, Sorcini, Daniele, Stella, Arianna, Esposito, Angela, Arcaleni, Roberta, Rosati, Emanuela, Sportoletti, Paolo
Published in International journal of molecular sciences (01.09.2024)
Published in International journal of molecular sciences (01.09.2024)
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A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis
Moretti, Silvia, Renga, Giorgia, Oikonomou, Vasilis, Galosi, Claudia, Pariano, Marilena, Iannitti, Rossana G., Borghi, Monica, Puccetti, Matteo, De Zuani, Marco, Pucillo, Carlo E., Paolicelli, Giuseppe, Zelante, Teresa, Renauld, Jean-Christophe, Bereshchenko, Oxana, Sportoletti, Paolo, Lucidi, Vincenzina, Russo, Maria Chiara, Colombo, Carla, Fiscarelli, Ersilia, Lass-Flörl, Cornelia, Majo, Fabio, Ricciotti, Gabriella, Ellemunter, Helmut, Ratclif, Luigi, Talesa, Vincenzo Nicola, Napolioni, Valerio, Romani, Luigina
Published in Nature communications (16.01.2017)
Published in Nature communications (16.01.2017)
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Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML
Gionfriddo, Ilaria, Brunetti, Lorenzo, Mezzasoma, Federica, Milano, Francesca, Cardinali, Valeria, Ranieri, Roberta, Venanzi, Alessandra, Pierangeli, Sara, Vetro, Calogero, Spinozzi, Giulio, Dorillo, Erica, Wu, Hsin Chieh, Berthier, Caroline, Ciurnelli, Raffaella, Griffin, Melanie J., Jennings, Claire E., Tiacci, Enrico, Sportoletti, Paolo, Falzetti, Franca, de Thé, Hugues, Veal, Gareth J., Martelli, Maria Paola, Falini, Brunangelo
Published in Leukemia (01.09.2021)
Published in Leukemia (01.09.2021)
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Management of infections for patient treated with ibrutinib in clinical practice
Baratè, Claudia, Scortechini, Ilaria, Ciofini, Sara, Picardi, Paola, Angeletti, Ilaria, Loscocco, Federica, Sanna, Alessandro, Isidori, Alessandro, Sportoletti, Paolo
Published in Frontiers in oncology (10.09.2024)
Published in Frontiers in oncology (10.09.2024)
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Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice
Sportoletti, Paolo, Sorcini, Daniele, Guzman, Anna G., Reyes, Jaime M., Stella, Arianna, Marra, Andrea, Sartori, Sara, Brunetti, Lorenzo, Rossi, Roberta, Papa, Beatrice Del, Adamo, Francesco Maria, Pianigiani, Giulia, Betti, Camilla, Scialdone, Annarita, Guarente, Valerio, Spinozzi, Giulio, Tini, Valentina, Martelli, Maria Paola, Goodell, Margaret A., Falini, Brunangelo
Published in Leukemia (01.07.2021)
Published in Leukemia (01.07.2021)
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NK Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications
Sportoletti, Paolo, De Falco, Filomena, Del Papa, Beatrice, Baldoni, Stefano, Guarente, Valerio, Marra, Andrea, Dorillo, Erica, Rompietti, Chiara, Adamo, Francesco Maria, Ruggeri, Loredana, Di Ianni, Mauro, Rosati, Emanuela
Published in International journal of molecular sciences (01.07.2021)
Published in International journal of molecular sciences (01.07.2021)
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Genetic variation in NOTCH1 is associated with overweight and obesity in Brazilian elderly
Silva Barcelos, Estevão Carlos, Naslavsky, Michel Satya, Fernandes, Izadora Silveira, Scliar, Marilia Oliveira, Yamamoto, Guilherme Lopes, Wang, Jaqueline Yu Ting, Bride, Laís, de Sousa, Valdemir Pereira, Pimassoni, Lucia Helena Sagrillo, Sportoletti, Paolo, de Paula, Flavia, von Zeidler, Sandra Ventorin, Duarte, Yeda Aparecida Oliveira, Passos-Bueno, Maria Rita, Zatz, Mayana, Errera, Flávia Imbroisi Valle
Published in Scientific reports (24.07.2024)
Published in Scientific reports (24.07.2024)
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NOTCH1 Aberrations in Chronic Lymphocytic Leukemia
Rosati, Emanuela, Baldoni, Stefano, De Falco, Filomena, Del Papa, Beatrice, Dorillo, Erica, Rompietti, Chiara, Albi, Elisa, Falzetti, Franca, Di Ianni, Mauro, Sportoletti, Paolo
Published in Frontiers in oncology (27.06.2018)
Published in Frontiers in oncology (27.06.2018)
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GATA1 epigenetic deregulation contributes to the development of AML with NPM1 and FLT3-ITD cooperating mutations
Sportoletti, Paolo, Celani, Letizia, Varasano, Emanuela, Rossi, Roberta, Sorcini, Daniele, Rompietti, Chiara, Strozzini, Francesca, Del Papa, Beatrice, Guarente, Valerio, Spinozzi, Giulio, Cecchini, Debora, Bereshchenko, Oxana, Haferlach, Torsten, Martelli, Maria Paola, Falzetti, Franca, Falini, Brunangelo
Published in Leukemia (01.07.2019)
Published in Leukemia (01.07.2019)
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Synthesis and Characterization of ZIF-90 Nanoparticles as Potential Brain Cancer Therapy
Monarca, Lorenzo, Ragonese, Francesco, Sabbatini, Paola, Caglioti, Concetta, Stamegna, Matteo, Palazzetti, Federico, Sportoletti, Paolo, Costantino, Ferdinando, Fioretti, Bernard
Published in Pharmaceutics (01.03.2024)
Published in Pharmaceutics (01.03.2024)
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Wnt/β-Catenin Signaling Induces Integrin α4β1 in T Cells and Promotes a Progressive Neuroinflammatory Disease in Mice
Sorcini, Daniele, Bruscoli, Stefano, Frammartino, Tiziana, Cimino, Monica, Mazzon, Emanuela, Galuppo, Maria, Bramanti, Placido, Al-Banchaabouchi, Mumna, Farley, Dominika, Ermakova, Olga, Britanova, Olga, Izraelson, Mark, Chudakov, Dmitry, Biagioli, Michele, Sportoletti, Paolo, Flamini, Sara, Raspa, Marcello, Scavizzi, Ferdinando, Nerlov, Claus, Migliorati, Graziella, Riccardi, Carlo, Bereshchenko, Oxana
Published in The Journal of immunology (1950) (01.11.2017)
Published in The Journal of immunology (1950) (01.11.2017)
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NOTCH1 inhibition prevents GvHD and maintains GvL effect in murine models
Baldoni, Stefano, Ruggeri, Loredana, Del Papa, Beatrice, Sorcini, Daniele, Guardalupi, Francesco, Ulbar, Francesca, Marra, Andrea, Dorillo, Erica, Stella, Arianna, Giancola, Raffaella, Fabi, Bianca, Sola, Rosaria, Ciardelli, Sara, De Falco, Filomena, Rompietti, Chiara, Adamo, Francesco Maria, Rosati, Emanuela, Pierini, Antonio, Sorrentino, Carlo, Sportoletti, Paolo, Di Ianni, Mauro
Published in Bone marrow transplantation (Basingstoke) (01.08.2021)
Published in Bone marrow transplantation (Basingstoke) (01.08.2021)
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GSK3β is a critical, druggable component of the network regulating the active NOTCH1 protein and cell viability in CLL
De Falco, Filomena, Rompietti, Chiara, Sorcini, Daniele, Esposito, Angela, Scialdone, Annarita, Baldoni, Stefano, Del Papa, Beatrice, Adamo, Francesco Maria, Silva Barcelos, Estevão Carlos, Dorillo, Erica, Stella, Arianna, Di Ianni, Mauro, Screpanti, Isabella, Sportoletti, Paolo, Rosati, Emanuela
Published in Cell death & disease (01.09.2022)
Published in Cell death & disease (01.09.2022)
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NOTCH1-mutated chronic lymphocytic leukemia displays high endoplasmic reticulum stress response with druggable potential
Silva Barcelos, Estevão Carlos, Rompietti, Chiara, Adamo, Francesco Maria, Dorillo, Erica, De Falco, Filomena, Del Papa, Beatrice, Baldoni, Stefano, Nogarotto, Manuel, Esposito, Angela, Capoccia, Silvia, Geraci, Clelia, Sorcini, Daniele, Stella, Arianna, Arcaleni, Roberta, Tini, Valentina, Imbroisi Valle Errera, Flávia, Rosati, Emanuela, Sportoletti, Paolo
Published in Frontiers in oncology (25.09.2023)
Published in Frontiers in oncology (25.09.2023)
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