Glutamate and GABA in autism spectrum disorder—a translational magnetic resonance spectroscopy study in man and rodent models
Horder, Jamie, Petrinovic, Marija M., Mendez, Maria A., Bruns, Andreas, Takumi, Toru, Spooren, Will, Barker, Gareth J., Künnecke, Basil, Murphy, Declan G.
Published in Translational psychiatry (25.05.2018)
Published in Translational psychiatry (25.05.2018)
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Journal Article
Shared Synaptic Pathophysiology in Syndromic and Nonsyndromic Rodent Models of Autism
Baudouin, Stéphane J., Gaudias, Julien, Gerharz, Stefan, Hatstatt, Laetitia, Zhou, Kuikui, Punnakkal, Pradeep, Tanaka, Kenji F., Spooren, Will, Hen, Rene, De Zeeuw, Chris I., Vogt, Kaspar, Scheiffele, Peter
Published in Science (American Association for the Advancement of Science) (05.10.2012)
Published in Science (American Association for the Advancement of Science) (05.10.2012)
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Journal Article
Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder
Brunner, Daniela, Kabitzke, Patricia, He, Dansha, Cox, Kimberly, Thiede, Lucinda, Hanania, Taleen, Sabath, Emily, Alexandrov, Vadim, Saxe, Michael, Peles, Elior, Mills, Alea, Spooren, Will, Ghosh, Anirvan, Feliciano, Pamela, Benedetti, Marta, Luo Clayton, Alice, Biemans, Barbara
Published in PloS one (14.08.2015)
Published in PloS one (14.08.2015)
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Journal Article
Identification and validation of biomarkers for autism spectrum disorders
Loth, Eva, Spooren, Will, Ham, Lindsay M., Isaac, Maria B., Auriche-Benichou, Caroline, Banaschewski, Tobias, Baron-Cohen, Simon, Broich, Karl, Bölte, Sven, Bourgeron, Thomas, Charman, Tony, Collier, David, de Andres-Trelles, Fernando, Durston, Sarah, Ecker, Christine, Elferink, Andre, Haberkamp, Marion, Hemmings, Robert, Johnson, Mark H., Jones, Emily J. H., Khwaja, Omar S., Lenton, Sabine, Mason, Luke, Mantua, Valentina, Meyer-Lindenberg, Andreas, Lombardo, Michael V., O'Dwyer, Laurence, Okamoto, Koichi, Pandina, Gahan J., Pani, Luca, Persico, Antonio M., Simonoff, Emily, Tauscher-Wisniewski, Sitra, Llinares-Garcia, Jordi, Vamvakas, Spiros, Williams, Steve, Buitelaar, Jan K., Murphy, Declan G. M.
Published in Nature reviews. Drug discovery (01.01.2016)
Published in Nature reviews. Drug discovery (01.01.2016)
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Journal Article
NK3 receptor antagonists: the next generation of antipsychotics?
Spooren, Will, Riemer, Claus, Meltzer, Herbert
Published in Nature reviews. Drug discovery (01.12.2005)
Published in Nature reviews. Drug discovery (01.12.2005)
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Journal Article
CTEP: a novel, potent, long-acting, and orally bioavailable metabotropic glutamate receptor 5 inhibitor
Lindemann, Lothar, Jaeschke, Georg, Michalon, Aubin, Vieira, Eric, Honer, Michael, Spooren, Will, Porter, Richard, Hartung, Thomas, Kolczewski, Sabine, Büttelmann, Bernd, Flament, Christophe, Diener, Catherine, Fischer, Christophe, Gatti, Silvia, Prinssen, Eric P, Parrott, Neil, Hoffmann, Gerhard, Wettstein, Joseph G
Published in The Journal of pharmacology and experimental therapeutics (01.11.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2011)
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Journal Article
Social brain activation during mentalizing in a large autism cohort: the Longitudinal European Autism Project
Moessnang, Carolin, Baumeister, Sarah, Tillmann, Julian, Goyard, David, Charman, Tony, Ambrosino, Sara, Baron-Cohen, Simon, Beckmann, Christian, Bölte, Sven, Bours, Carsten, Crawley, Daisy, Dell'Acqua, Flavio, Durston, Sarah, Ecker, Christine, Frouin, Vincent, Hayward, Hannah, Holt, Rosemary, Johnson, Mark, Jones, Emily, Lai, Meng-Chuan, Lombardo, Michael V, Mason, Luke, Oldenhinkel, Marianne, Persico, Antonio, Cáceres, Antonia San José, Spooren, Will, Loth, Eva, Murphy, Declan G M, Buitelaar, Jan K, Banaschewski, Tobias, Brandeis, Daniel, Tost, Heike, Meyer-Lindenberg, Andreas
Published in Molecular autism (22.02.2020)
Published in Molecular autism (22.02.2020)
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Journal Article
Reproducibility via coordinated standardization: a multi-center study in a Shank2 genetic rat model for Autism Spectrum Disorders
Arroyo-Araujo, María, Graf, Radka, Maco, Martine, van Dam, Elsbeth, Schenker, Esther, Drinkenburg, Wilhelmus, Koopmans, Bastijn, de Boer, Sietse F., Cullum-Doyle, Michaela, Noldus, Lucas P. J. J., Loos, Maarten, van Dommelen, Wil, Spooren, Will, Biemans, Barbara, Buhl, Derek L., Kas, Martien J.
Published in Scientific reports (12.08.2019)
Published in Scientific reports (12.08.2019)
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Journal Article
Pharmacological and endocrinological characterisation of stress-induced hyperthermia in singly housed mice using classical and candidate anxiolytics (LY314582, MPEP and NKP608)
Spooren, Will P.J.M, Schoeffter, Philippe, Gasparini, Fabrizio, Kuhn, Rainer, Gentsch, Conrad
Published in European journal of pharmacology (25.01.2002)
Published in European journal of pharmacology (25.01.2002)
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Journal Article
Neuropathology in Mice Expressing Human alpha -Synuclein
van der Putten, Herman, Wiederhold, Karl-Heinz, Probst, Alphonse, Barbieri, Samuel, Mistl, Claudia, Danner, Simone, Kauffmann, Sabine, Hofele, Katja, Spooren, Will P. J. M, Ruegg, Markus A, Lin, Shuo, Caroni, Pico, Sommer, Bernd, Tolnay, Markus, Bilbe, Graeme
Published in The Journal of neuroscience (15.08.2000)
Published in The Journal of neuroscience (15.08.2000)
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Journal Article
Behavioral Characterization of the Novel GABAB Receptor-Positive Modulator GS39783 (N,Nâ²-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): Anxiolytic-Like Activity without Side Effects Associated with Baclofen or Benzodiazepines
Cryan, John F, Kelly, Peter H, Chaperon, Frederique, Gentsch, Conrad, Mombereau, Cedric, Lingenhoehl, Kurt, Froestl, Wolfgang, Bettler, Bernhard, Kaupmann, Klemens, Spooren, Will P J M
Published in The Journal of pharmacology and experimental therapeutics (01.09.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2004)
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Journal Article
Fenobam: A Clinically Validated Nonbenzodiazepine Anxiolytic Is a Potent, Selective, and Noncompetitive mGlu5 Receptor Antagonist with Inverse Agonist Activity
Porter, Richard H P, Jaeschke, Georg, Spooren, Will, Ballard, Theresa M, Büttelmann, Bernd, Kolczewski, Sabine, Peters, Jens-Uwe, Prinssen, Eric, Wichmann, Jürgen, Vieira, Eric, Mühlemann, Andreas, Gatti, Silvia, Mutel, Vincent, Malherbe, Pari
Published in The Journal of pharmacology and experimental therapeutics (01.11.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2005)
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Journal Article
Transcriptome signatures from discordant sibling pairs reveal changes in peripheral blood immune cell composition in Autism Spectrum Disorder
Filosi, Michele, Kam-Thong, Tony, Essioux, Laurent, Muglia, Pierandrea, Trabetti, Elisabetta, Spooren, Will, Müller-Myshok, Bertram, Domenici, Enrico
Published in Translational psychiatry (14.04.2020)
Published in Translational psychiatry (14.04.2020)
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Journal Article
Effects of the prototypical mGlu5 receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine on rotarod, locomotor activity and rotational responses in unilateral 6-OHDA-lesioned rats
SPOOREN, Will P. J. M, GASPARINI, Fabrizio, BERGMANN, Reinhard, KUHN, Rainer
Published in European journal of pharmacology (01.10.2000)
Published in European journal of pharmacology (01.10.2000)
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Journal Article
Me-Talnetant and Osanetant Interact within Overlapping but Not Identical Binding Pockets in the Human Tachykinin Neurokinin 3 Receptor Transmembrane Domains
Malherbe, Pari, Bissantz, Caterina, Marcuz, Anne, Kratzeisen, Claudia, Zenner, Marie-Thérèse, Wettstein, Joseph G, Ratni, Hasane, Riemer, Claus, Spooren, Will
Published in Molecular pharmacology (01.06.2008)
Published in Molecular pharmacology (01.06.2008)
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Journal Article
Different Outcomes of the Wilcoxon-Mann-Whitney Test from Different Statistics Packages
Bergmann, Reinhard, Ludbrook, John, Spooren, Will P. J. M.
Published in The American statistician (01.02.2000)
Published in The American statistician (01.02.2000)
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Journal Article
Differential effects of diazepam and MPEP on habituation and neuro-behavioural processes in inbred mice
Salomons, Amber R, Pinzon, Nathaly Espitia, Boleij, Hetty, Kirchhoff, Susanne, Arndt, Saskia S, Nordquist, Rebecca E, Lindemann, Lothar, Jaeschke, Georg, Spooren, Will, Ohl, Frauke
Published in Behavioral and brain functions (11.06.2012)
Published in Behavioral and brain functions (11.06.2012)
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