Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis
Tabibian, James H., O'Hara, Steven P., Trussoni, Christy E., Tietz, Pamela S., Splinter, Patrick L., Mounajjed, Taofic, Hagey, Lee R., LaRusso, Nicholas F.
Published in Hepatology (Baltimore, Md.) (01.01.2016)
Published in Hepatology (Baltimore, Md.) (01.01.2016)
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Journal Article
Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice
Guicciardi, Maria Eugenia, Trussoni, Christy E., Krishnan, Anuradha, Bronk, Steven F., Lorenzo Pisarello, Maria J., O'Hara, Steven P., Splinter, Patrick L., Gao, Yandong, Vig, Pamela, Revzin, Alexander, LaRusso, Nicholas F., Gores, Gregory J.
Published in Journal of hepatology (01.09.2018)
Published in Journal of hepatology (01.09.2018)
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Journal Article
A Cellular Micro-RNA, let-7i, Regulates Toll-like Receptor 4 Expression and Contributes to Cholangiocyte Immune Responses against Cryptosporidium parvum Infection
Chen, Xian-Ming, Splinter, Patrick L., O'Hara, Steven P., LaRusso, Nicholas F.
Published in The Journal of biological chemistry (28.09.2007)
Published in The Journal of biological chemistry (28.09.2007)
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Journal Article
The dynamic biliary epithelia: Molecules, pathways, and disease
O’Hara, Steven P, Tabibian, James H, Splinter, Patrick L, LaRusso, Nicholas F
Published in Journal of hepatology (01.03.2013)
Published in Journal of hepatology (01.03.2013)
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Journal Article
Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling
Masyuk, Anatoliy I, Huang, Bing Q, Radtke, Brynn N, Gajdos, Gabriella B, Splinter, Patrick L, Masyuk, Tatyana V, Gradilone, Sergio A, LaRusso, Nicholas F
Published in American journal of physiology: Gastrointestinal and liver physiology (01.06.2013)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.06.2013)
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Journal Article
ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A
O'Hara, Steven P., Splinter, Patrick L., Trussoni, Christy E., Pisarello, Maria J. Lorenzo, Loarca, Lorena, Splinter, Noah S., Schutte, Bryce F., LaRusso, Nicholas F.
Published in The Journal of biological chemistry (24.03.2017)
Published in The Journal of biological chemistry (24.03.2017)
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Journal Article
Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion
Gradilone, Sergio A, Masyuk, Anatoliy I, Splinter, Patrick L, Banales, Jesus M, Huang, Bing Q, Tietz, Pamela S, Masyuk, Tatyana V, LaRusso, Nicholas F
Published in Proceedings of the National Academy of Sciences - PNAS (27.11.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (27.11.2007)
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Journal Article
Cholangiocyte N-Ras Protein Mediates Lipopolysaccharide-induced Interleukin 6 Secretion and Proliferation
O'Hara, Steven P., Splinter, Patrick L., Trussoni, Christy E., Gajdos, Gabriella B., Lineswala, Pooja N., LaRusso, Nicholas F.
Published in The Journal of biological chemistry (02.09.2011)
Published in The Journal of biological chemistry (02.09.2011)
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Journal Article
Aquaporin-1 Promotes Angiogenesis, Fibrosis, and Portal Hypertension Through Mechanisms Dependent on Osmotically Sensitive MicroRNAs
Huebert, Robert C, Jagavelu, Kumaravelu, Hendrickson, Helen I, Vasdev, Meher M, Arab, Juan P, Splinter, Patrick L, Trussoni, Christy E, LaRusso, Nicholas F, Shah, Vijay H
Published in The American journal of pathology (01.10.2011)
Published in The American journal of pathology (01.10.2011)
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Journal Article
MicroRNAs: key modulators of posttranscriptional gene expression
O'Hara, Steven P, Mott, Justin L, Splinter, Patrick L, Gores, Gregory J, LaRusso, Nicholas F
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2009)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2009)
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Journal Article
Opisthorchis viverrini excretory/secretory products induce toll-like receptor 4 upregulation and production of interleukin 6 and 8 in cholangiocyte
Ninlawan, Kantima, O'Hara, Steve P, Splinter, Patrick L, Yongvanit, Puangrat, Kaewkes, Sasithorn, Surapaitoon, Arpa, LaRusso, Nicholas F, Sripa, Banchob
Published in Parasitology international (01.12.2010)
Published in Parasitology international (01.12.2010)
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Journal Article
Activation of Trpv4 reduces the hyperproliferative phenotype of cystic cholangiocytes from an animal model of ARPKD
Gradilone, Sergio A, Masyuk, Tatyana V, Huang, Bing Q, Banales, Jesus M, Lehmann, Guillermo L, Radtke, Brynn N, Stroope, Angela, Masyuk, Anatoliy I, Splinter, Patrick L, LaRusso, Nicholas F
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2010)
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Journal Article
Immortalized liver endothelial cells: a cell culture model for studies of motility and angiogenesis
Huebert, Robert C, Jagavelu, Kumaravelu, Liebl, Ann F, Huang, Bing Q, Splinter, Patrick L, LaRusso, Nicholas F, Urrutia, Raul A, Shah, Vijay H
Published in Laboratory investigation (01.12.2010)
Published in Laboratory investigation (01.12.2010)
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Journal Article
Localized Glucose and Water Influx Facilitates Cryptosporidium parvum Cellular Invasion by Means of Modulation of Host-Cell Membrane Protrusion
Chen, Xian-Ming, O'Hara, Steven P., Huang, Bing Q., Splinter, Patrick L., Nelson, Jeremy B., LaRusso, Nicholas F., Agre, Peter C.
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2005)
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Journal Article
Aquaporin-8 Is Involved in Water Transport in Isolated Superficial Colonocytes from Rat Proximal Colon
Laforenza, Umberto, Cova, Emanuela, Gastaldi, Giulia, Tritto, Simona, Grazioli, Monica, LaRusso, Nicholas F, Splinter, Patrick L, D'Adamo, Patrizia, Tosco, Marisa, Ventura, Ulderico
Published in The Journal of nutrition (01.10.2005)
Published in The Journal of nutrition (01.10.2005)
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Journal Article
Cholangiocyte Myosin IIB Is Required for Localized Aggregation of Sodium Glucose Cotransporter 1 to Sites of Cryptosporidium parvum Cellular Invasion and Facilitates Parasite Internalization
O'Hara, Steven P, Gajdos, Gabriella B, Trussoni, Christy E, Splinter, Patrick L, LaRusso, Nicholas F
Published in Infection and Immunity (01.07.2010)
Published in Infection and Immunity (01.07.2010)
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Journal Article
Targeting senescent cholangiocytes and activated fibroblasts with B‐cell lymphoma‐extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2−/−) mice
Moncsek, Anja, Al‐Suraih, Mohammed S., Trussoni, Christy E., O'Hara, Steven P., Splinter, Patrick L., Zuber, Camille, Patsenker, Eleonora, Valli, Piero V., Fingas, Christian D., Weber, Achim, Zhu, Yi, Tchkonia, Tamar, Kirkland, James L., Gores, Gregory J., Müllhaupt, Beat, LaRusso, Nicholas F., Mertens, Joachim C.
Published in Hepatology (Baltimore, Md.) (01.01.2018)
Published in Hepatology (Baltimore, Md.) (01.01.2018)
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Journal Article
Phosphatidylinositol 3-Kinase and Frabin Mediate Cryptosporidium parvum Cellular Invasion via Activation of Cdc42
Chen, Xian-Ming, Splinter, Patrick L, Tietz, Pamela S, Huang, Bing Q, Billadeau, Daniel D, LaRusso, Nicholas F
Published in The Journal of biological chemistry (23.07.2004)
Published in The Journal of biological chemistry (23.07.2004)
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