A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner
Stemmer, Willem P C, Schellenberger, Volker, Wang, Chia-wei, Geething, Nathan C, Spink, Benjamin J, Campbell, Andrew, To, Wayne, Scholle, Michael D, Yin, Yong, Yao, Yi, Bogin, Oren, Cleland, Jeffrey L, Silverman, Joshua
Published in Nature biotechnology (01.12.2009)
Published in Nature biotechnology (01.12.2009)
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Journal Article
Dynamic Charge Interactions Create Surprising Rigidity in the ER/K αa-Helical Protein Motif
Sivaramakrishnan, Sivaraj, Spink, Benjamin J., Sim, Adelene Y. L., Doniach, Sebastian, Spudich, James A.
Published in Proceedings of the National Academy of Sciences - PNAS (09.09.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (09.09.2008)
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Journal Article
Gcg-XTEN: an improved glucagon capable of preventing hypoglycemia without increasing baseline blood glucose
Geething, Nathan C, To, Wayne, Spink, Benjamin J, Scholle, Michael D, Wang, Chia-wei, Yin, Yong, Yao, Yi, Schellenberger, Volker, Cleland, Jeffrey L, Stemmer, Willem P C, Silverman, Joshua
Published in PloS one (14.04.2010)
Published in PloS one (14.04.2010)
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A Novel Long-Acting Human Growth Hormone Fusion Protein (VRS-317): Enhanced In Vivo Potency and Half-Life
Cleland, Jeffrey L., Geething, Nathan C., Moore, Jerome A., Rogers, Brian C., Spink, Benjamin J., Wang, Chai-Wei, Alters, Susan E., Stemmer, Willem P.C., Schellenberger, Volker
Published in Journal of pharmaceutical sciences (01.08.2012)
Published in Journal of pharmaceutical sciences (01.08.2012)
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Journal Article
GLP2-2G-XTEN: a pharmaceutical protein with improved serum half-life and efficacy in a rat Crohn's disease model
Alters, Susan E, McLaughlin, Bryant, Spink, Benjamin, Lachinyan, Tigran, Wang, Chia-wei, Podust, Vladimir, Schellenberger, Volker, Stemmer, Willem P C
Published in PloS one (26.11.2012)
Published in PloS one (26.11.2012)
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A Flexible Domain Is Essential for the Large Step Size and Processivity of Myosin VI
Rock, Ronald S., Ramamurthy, Bhagavathi, Dunn, Alexander R., Beccafico, Sara, Rami, Bhadresh R., Morris, Carl, Spink, Benjamin J., Franzini-Armstrong, Clara, Spudich, James A., Sweeney, H.Lee
Published in Molecular cell (18.02.2005)
Published in Molecular cell (18.02.2005)
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GLP2-2G-XTEN: a pharmaceutical protein with improved serum half-life and efficacy in a rat Crohn's. PLoS One. 2012; 7(11): e50630
Alters, Susan E, McLaughlin, Bryant, Spink, Benjamin, Lachinyan, Tigran, Wang, Chia-Wei, Podust, Vladimir, Schellenberger, Volker, Stemmer, Willem P C
Published in PloS one (2013)
Published in PloS one (2013)
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Journal Article
Correction: GLP2-2G-XTEN: A Pharmaceutical Protein with Improved Serum Half-Life and Efficacy in a Rat Crohn’s Disease Model
Alters, Susan E., McLaughlin, Bryant, Spink, Benjamin, Lachinyan, Tigran, Wang, Chia-wei, Podust, Vladimir, Schellenberger, Volker, Stemmer, Willem P. C.
Published in PloS one (10.06.2013)
Published in PloS one (10.06.2013)
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Journal Article
Dynamic charge interactions create surprising rigidity in the ER/K [alpha]-helical protein motif
Sivaramakrishnan, Sivaraj, Spink, Benjamin J., Sim, Adelene Y.L., Doniach, Sebastian, Spudich, James A.
Published in Proceedings of the National Academy of Sciences - PNAS (30.06.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (30.06.2009)
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Journal Article
Dynamic charge interactions create surprising rigidity in the ER/K [alpha]-helical protein motif
Sivaramakrishnan, Sivaraj, Spink, Benjamin J, Sim, Adelene Y L, Doniach, Sebastian, Spudich, James A
Published in Proceedings of the National Academy of Sciences - PNAS (09.09.2008)
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Published in Proceedings of the National Academy of Sciences - PNAS (09.09.2008)
Journal Article
GLUCAGON-LIKE PEPTIDE-2 COMPOSITIONS AND METHODS OF MAKING AND USING SAME
GEETHING NATHAN, WANG CHIA WEI, STEMMER WILLEM P, SILVERMAN JOSHUA, SCHELLENBERGER VOLKER, SPINK BENJAMIN
Year of Publication 09.06.2014
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Year of Publication 09.06.2014
Patent
FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
CHANG PEI YUN, JIANG HAIYAN, DING SHENG, VARFAJ FATBARDHA, PETERS ROBERT, SPINK BENJAMIN, LIU TONGYAO, GEETHING NATHAN, MEI BAISONG, KULMAN JOHN, WANG CHIA WEI, WANG DEPING, STEMMER WILLEM P, SILVERMAN JOSHUA, SCHELLENBERGER VOLKER, TOBY GARABET G
Year of Publication 21.11.2014
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Year of Publication 21.11.2014
Patent
GLUCAGON-LIKE PEPTIDE-2 COMPOSITIONS AND METHODS OF MAKING AND USING SAME
STEMMER, Willem P, GEETHING, Nathan, SCHELLENBERGER, Volker, WANG, Chia-wei, SILVERMAN, Joshua, SPINK, Benjamin
Year of Publication 29.02.2024
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Year of Publication 29.02.2024
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