Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation
Toffalori, Cristina, Zito, Laura, Gambacorta, Valentina, Riba, Michela, Oliveira, Giacomo, Bucci, Gabriele, Barcella, Matteo, Spinelli, Orietta, Greco, Raffaella, Crucitti, Lara, Cieri, Nicoletta, Noviello, Maddalena, Manfredi, Francesco, Montaldo, Elisa, Ostuni, Renato, Naldini, Matteo M., Gentner, Bernhard, Waterhouse, Miguel, Zeiser, Robert, Finke, Jurgen, Hanoun, Maher, Beelen, Dietrich W., Gojo, Ivana, Luznik, Leo, Onozawa, Masahiro, Teshima, Takanori, Devillier, Raynier, Blaise, Didier, Halkes, Constantijn J. M., Griffioen, Marieke, Carrabba, Matteo G., Bernardi, Massimo, Peccatori, Jacopo, Barlassina, Cristina, Stupka, Elia, Lazarevic, Dejan, Tonon, Giovanni, Rambaldi, Alessandro, Cittaro, Davide, Bonini, Chiara, Fleischhauer, Katharina, Ciceri, Fabio, Vago, Luca
Published in Nature medicine (01.04.2019)
Published in Nature medicine (01.04.2019)
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High Frequency and Poor Outcome of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Adults
Roberts, Kathryn G, Gu, Zhaohui, Payne-Turner, Debbie, McCastlain, Kelly, Harvey, Richard C, Chen, I-Ming, Pei, Deqing, Iacobucci, Ilaria, Valentine, Marcus, Pounds, Stanley B, Shi, Lei, Li, Yongjin, Zhang, Jinghui, Cheng, Cheng, Rambaldi, Alessandro, Tosi, Manuela, Spinelli, Orietta, Radich, Jerald P, Minden, Mark D, Rowe, Jacob M, Luger, Selina, Litzow, Mark R, Tallman, Martin S, Wiernik, Peter H, Bhatia, Ravi, Aldoss, Ibrahim, Kohlschmidt, Jessica, Mrózek, Krzysztof, Marcucci, Guido, Bloomfield, Clara D, Stock, Wendy, Kornblau, Stephen, Kantarjian, Hagop M, Konopleva, Marina, Paietta, Elisabeth, Willman, Cheryl L, Mullighan, Charles G
Published in Journal of clinical oncology (01.02.2017)
Published in Journal of clinical oncology (01.02.2017)
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Philadelphia-like acute lymphoblastic leukemia is associated with minimal residual disease persistence and poor outcome. First report of the minimal residual disease-oriented GIMEMA LAL1913
Chiaretti, Sabina, Messina, Monica, Della Starza, Irene, Piciocchi, Alfonso, Cafforio, Luciana, Cavalli, Marzia, Taherinasab, Akram, Ansuinelli, Michela, Elia, Loredana, Albertini Petroni, Guglielmo, La Starza, Roberta, Canichella, Martina, Lauretti, Alessia, Puzzolo, Maria Cristina, Pierini, Valentina, Santoro, Alessandra, Spinelli, Orietta, Apicella, Valerio, Capria, Saveria, Di Raimondo, Francesco, De Fabritiis, Paolo, Papayannidis, Cristina, Candoni, Anna, Cairoli, Roberto, Cerrano, Marco, Fracchiolla, Nicola, Mattei, Daniele, Cattaneo, Chiara, Vitale, Antonella, Crea, Enrico, Fazi, Paola, Mecucci, Cristina, Rambaldi, Alessandro, Guarini, Anna, Bassan, Renato, Foà, Robin
Published in Haematologica (Roma) (01.06.2021)
Published in Haematologica (Roma) (01.06.2021)
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IDH1-R132 changes vary according to NPM1 and other mutations status in AML
Falini, Brunangelo, Spinelli, Orietta, Meggendorfer, Manja, Martelli, Maria Paola, Bigerna, Barbara, Ascani, Stefano, Stein, Harald, Rambaldi, Alessandro, Haferlach, Torsten
Published in Leukemia (01.04.2019)
Published in Leukemia (01.04.2019)
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Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL)
Bassan, Renato, Spinelli, Orietta, Oldani, Elena, Intermesoli, Tamara, Tosi, Manuela, Peruta, Barbara, Rossi, Giuseppe, Borlenghi, Erika, Pogliani, Enrico M., Terruzzi, Elisabetta, Fabris, Pietro, Cassibba, Vincenzo, Lambertenghi-Deliliers, Giorgio, Cortelezzi, Agostino, Bosi, Alberto, Gianfaldoni, Giacomo, Ciceri, Fabio, Bernardi, Massimo, Gallamini, Andrea, Mattei, Daniele, Di Bona, Eros, Romani, Claudio, Scattolin, Anna Maria, Barbui, Tiziano, Rambaldi, Alessandro
Published in Blood (30.04.2009)
Published in Blood (30.04.2009)
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Chemotherapy-Phased Imatinib Pulses Improve Long-Term Outcome of Adult Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Northern Italy Leukemia Group Protocol 09/00
BASSAN, Renato, ROSSI, Giuseppe, MATTEI, Daniele, BORLENGHI, Erika, TERRUZZI, Elisabetta, BORGHERO, Carlo, ROMANI, Claudio, SPINELLI, Orietta, TOSI, Manuela, OLDANI, Elena, INTERMESOLI, Tamara, RAMBALDI, Alessandro, POGLIANI, Enrico M, DI BONA, Eros, ANGELUCCI, Emanuele, CAVATTONI, Irene, LAMBERTENGHI-DELILIERS, Giorgio, MANNELLI, Francesco, LEVIS, Alessandro, CICERI, Fabio
Published in Journal of clinical oncology (01.08.2010)
Published in Journal of clinical oncology (01.08.2010)
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Updated risk-oriented strategy for acute lymphoblastic leukemia in adult patients 18–65 years: NILG ALL 10/07
Bassan, Renato, Pavoni, Chiara, Intermesoli, Tamara, Spinelli, Orietta, Tosi, Manuela, Audisio, Ernesta, Marmont, Filippo, Cattaneo, Chiara, Borlenghi, Erika, Cortelazzo, Sergio, Cavattoni, Irene, Fumagalli, Monica, Mattei, Daniele, Romani, Claudio, Cortelezzi, Agostino, Fracchiolla, Nicola, Ciceri, Fabio, Bernardi, Massimo, Scattolin, Anna Maria, Depaoli, Lorella, Masciulli, Arianna, Oldani, Elena, Rambaldi, Alessandro
Published in Blood cancer journal (New York) (13.11.2020)
Published in Blood cancer journal (New York) (13.11.2020)
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CEBPA -double-mutated acute myeloid leukemia displays a unique phenotypic profile: a reliable screening method and insight into biological features
Mannelli, Francesco, Ponziani, Vanessa, Bencini, Sara, Bonetti, Maria Ida, Benelli, Matteo, Cutini, Ilaria, Gianfaldoni, Giacomo, Scappini, Barbara, Pancani, Fabiana, Piccini, Matteo, Rondelli, Tommaso, Caporale, Roberto, Gelli, Anna Maria Grazia, Peruzzi, Benedetta, Chiarini, Marco, Borlenghi, Erika, Spinelli, Orietta, Giupponi, Damiano, Zanghì, Pamela, Bassan, Renato, Rambaldi, Alessandro, Rossi, Giuseppe, Bosi, Alberto
Published in Haematologica (Roma) (01.03.2017)
Published in Haematologica (Roma) (01.03.2017)
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Targeting CDK6 and BCL2 Exploits the "MYB Addiction" of Ph + Acute Lymphoblastic Leukemia
De Dominici, Marco, Porazzi, Patrizia, Soliera, Angela Rachele, Mariani, Samanta A, Addya, Sankar, Fortina, Paolo, Peterson, Luke F, Spinelli, Orietta, Rambaldi, Alessandro, Martinelli, Giovanni, Ferrari, Anna, Iacobucci, Ilaria, Calabretta, Bruno
Published in Cancer research (Chicago, Ill.) (15.02.2018)
Published in Cancer research (Chicago, Ill.) (15.02.2018)
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Clinical significance of chromatin-spliceosome acute myeloid leukemia: a report from the Northern Italy Leukemia Group (NILG) randomized trial 02/06
Caprioli, Chiara, Lussana, Federico, Salmoiraghi, Silvia, Cavagna, Roberta, Buklijas, Ksenija, Elidi, Lara, Zanghi', Pamela, Michelato, Anna, Delaini, Federica, Oldani, Elena, Intermesoli, Tamara, Grassi, Anna, Gianfaldoni, Giacomo, Mannelli, Francesco, Ferrero, Dario, Audisio, Ernesta, Terruzzi, Elisabetta, De Paoli, Lorella, Cattaneo, Chiara, Borlenghi, Erika, Cavattoni, Irene, Tajana, Monica, Scattolin, Anna Maria, Mattei, Daniele, Corradini, Paolo, Campiotti, Leonardo, Ciceri, Fabio, Bernardi, Massimo, Todisco, Elisabetta, Cortelezzi, Agostino, Falini, Brunangelo, Pavoni, Chiara, Bassan, Renato, Spinelli, Orietta, Rambaldi, Alessandro
Published in Haematologica (Roma) (27.08.2020)
Published in Haematologica (Roma) (27.08.2020)
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Minimally manipulated whole human umbilical cord is a rich source of clinical-grade human mesenchymal stromal cells expanded in human platelet lysate
Capelli, Chiara, Gotti, Elisa, Morigi, Marina, Rota, Cinzia, Weng, Ling, Dazzi, Francesco, Spinelli, Orietta, Cazzaniga, Giovanni, Trezzi, Rosangela, Gianatti, Andrea, Rambaldi, Alessandro, Golay, Josee, Introna, Martino
Published in Cytotherapy (Oxford, England) (01.08.2011)
Published in Cytotherapy (Oxford, England) (01.08.2011)
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Nanopore Targeted Sequencing for Rapid Gene Mutations Detection in Acute Myeloid Leukemia
Cumbo, Cosimo, Minervini, Crescenzio Francesco, Orsini, Paola, Anelli, Luisa, Zagaria, Antonella, Minervini, Angela, Coccaro, Nicoletta, Impera, Luciana, Tota, Giuseppina, Parciante, Elisa, Conserva, Maria Rosa, Spinelli, Orietta, Rambaldi, Alessandro, Specchia, Giorgina, Albano, Francesco
Published in Genes (09.12.2019)
Published in Genes (09.12.2019)
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Concurrent diagnosis of acute myeloid leukemia and symptomatic COVID-19 infection: a case report successfully treated with Azacitidine-Venetoclax combination
Taurino, Daniela, Frigeni, Marco, Grassi, Anna, Cavallaro, Gianluca, Salmoiraghi, Silvia, Spinelli, Orietta, Rambaldi, Alessandro, Lussana, Federico
Published in Mediterranean journal of hematology and infectious diseases (01.09.2021)
Published in Mediterranean journal of hematology and infectious diseases (01.09.2021)
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Targeting NOTCH1 in combination with antimetabolite drugs prolongs life span in relapsed pediatric and adult T-acute lymphoblastic leukemia xenografts
Minuzzo, Sonia, Agnusdei, Valentina, Pinazza, Marica, Amaro, Adriana A, Sacchetto, Valeria, Pfeffer, Ulrich, Bertorelle, Roberta, Spinelli, Orietta, Serafin, Valentina, Indraccolo, Stefano
Published in Experimental hematology & oncology (04.09.2023)
Published in Experimental hematology & oncology (04.09.2023)
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Mutations of TP53 gene in adult acute lymphoblastic leukemia at diagnosis do not affect the achievement of hematologic response but correlate with early relapse and very poor survival
Salmoiraghi, Silvia, Montalvo, Marie Lorena Guinea, Ubiali, Greta, Tosi, Manuela, Peruta, Barbara, Zanghi, Pamela, Oldani, Elena, Boschini, Cristina, Kohlmann, Alexander, Bungaro, Silvia, Intermesoli, Tamara, Terruzzi, Elisabetta, Angelucci, Emanuele, Cavattoni, Irene, Ciceri, Fabio, Bassan, Renato, Rambaldi, Alessandro, Spinelli, Orietta
Published in Haematologica (Roma) (01.06.2016)
Published in Haematologica (Roma) (01.06.2016)
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In Ph+BCR-ABL1P210+ acute lymphoblastic leukemia the e13a2 (B2A2) transcript is prevalent
Baccarani, Michele, Iacobucci, Ilaria, Chiaretti, Sabina, Foà’, Robin, Balasubramanian, Poonkuzhali, Paietta, Elisabeth, Foroni, Letizia, Jeromin, Sabine, Izzo, Barbara, Spinelli, Orietta, Varma, Neelam, Menif, Samia, Terragna, Carolina, Seth, Tulika, Bidet, Audrey, Coriu, Daniel, Lunghi, Francesca, Mayer, Jiri, Scappini, Barbara, Langabeer, Stephen, Maier, Jacqueline, Burt, Emma, Candoni, Anna, Albano, Francesco, Luppi, Mario, Zupan, Irena, Lion, Thomas, Zadro, Renata, di Raimondo, Francesco, Poopak, Behzad, Rege-Cambrin, Giovanna, Annunziata, Mario, Ayala, Ana, Salinas-Viedma, Victor, Ines Prado, Ana, Milner, Benedict, Galimberti, Sara, Janssen, Jeroen, Polli, Valentina, Comba, Lorenzo, Borsellino, Beatrice, Annibali, Ombretta, Crugnola, Monica, Passamonti, Francesco
Published in Leukemia (01.03.2020)
Published in Leukemia (01.03.2020)
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Frequent occurrence of non-malignant genetic alterations in clinical grade mesenchymal stromal cells expanded for cell therapy protocols
Capelli, Chiara, Pedrini, Olga, Cassina, Gisella, Spinelli, Orietta, Salmoiraghi, Silvia, Golay, Josée, Rambaldi, Alessandro, Giussani, Ursula, Introna, Martino
Published in Haematologica (Roma) (01.06.2014)
Published in Haematologica (Roma) (01.06.2014)
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Repeated infusions of donor-derived cytokine-induced killer cells in patients relapsing after allogeneic stem cell transplantation: a phase I study
Introna, Martino, Borleri, Gianmaria, Conti, Elena, Franceschetti, Marta, Barbui, Anna Maria, Broady, Raewyn, Dander, Erica, Gaipa, Giuseppe, D'Amico, Giovanna, Biagi, Ettore, Parma, Matteo, Pogliani, Enrico M, Spinelli, Orietta, Baronciani, Donatella, Grassi, Anna, Golay, Josee, Barbui, Tiziano, Biondi, Andrea, Rambaldi, Alessandro
Published in Haematologica (Roma) (01.07.2007)
Published in Haematologica (Roma) (01.07.2007)
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Sequential allogeneic transplantation and ruxolitinib maintenance for a synchronous PCM1‐JAK2 positive myeloid sarcoma and acute B‐lymphoblastic leukemia
Rizzuto, Giuliana, Leoncin, Matteo, Imbergamo, Silvia, Taurino, Daniela, Mico, Maria Caterina, Tosi, Manuela, Michelato, Anna, Buklijas, Ksenija, Spinelli, Orietta, Lussana, Federico, Lessi, Federica, Pizzi, Marco, Bonaldi, Laura, Binotto, Gianni, Rambaldi, Alessandro, Gurrieri, Carmela
Published in Clinical case reports (01.01.2022)
Published in Clinical case reports (01.01.2022)
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Randomized trial of radiation-free central nervous system prophylaxis comparing intrathecal triple therapy with liposomal cytarabine in acute lymphoblastic leukemia
Bassan, Renato, Masciulli, Arianna, Intermesoli, Tamara, Audisio, Ernesta, Rossi, Giuseppe, Pogliani, Enrico Maria, Cassibba, Vincenzo, Mattei, Daniele, Romani, Claudio, Cortelezzi, Agostino, Corti, Consuelo, Scattolin, Anna Maria, Spinelli, Orietta, Tosi, Manuela, Parolini, Margherita, Marmont, Filippo, Borlenghi, Erika, Fumagalli, Monica, Cortelazzo, Sergio, Gallamini, Andrea, Marfisi, Rosa Maria, Oldani, Elena, Rambaldi, Alessandro
Published in Haematologica (Roma) (01.06.2015)
Published in Haematologica (Roma) (01.06.2015)
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