Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution
Gao, Mengqing, Wang, Jin, Rousseaux, Sophie, Tan, Minjia, Pan, Lulu, Peng, Lijun, Wang, Sisi, Xu, Wenqian, Ren, Jiayi, Liu, Yuanfang, Spinck, Martin, Barral, Sophie, Wang, Tao, Chuffart, Florent, Bourova-Flin, Ekaterina, Puthier, Denis, Curtet, Sandrine, Bargier, Lisa, Cheng, Zhongyi, Neumann, Heinz, Li, Jian, Zhao, Yingming, Mi, Jian-Qing, Khochbin, Saadi
Published in Cell reports (Cambridge) (27.07.2021)
Published in Cell reports (Cambridge) (27.07.2021)
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Journal Article
A Directed Evolution System for Lysine Deacetylases
Spinck, Martin, Ecke, Maria, Schiller, Damian, Neumann, Heinz
Published in Methods in molecular biology (Clifton, N.J.) (2021)
Published in Methods in molecular biology (Clifton, N.J.) (2021)
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Journal Article
Highly Sensitive Lysine Deacetylase Assay Based on Acetylated Firefly Luciferase
Spinck, Martin, Ecke, Maria, Sievers, Sonja, Neumann, Heinz
Published in Biochemistry (Easton) (03.07.2018)
Published in Biochemistry (Easton) (03.07.2018)
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Journal Article
Discovery of Dihydro-1,4-Benzoxazine Carboxamides as Potent and Highly Selective Inhibitors of Sirtuin‑1
Spinck, Martin, Bischoff, Matthias, Lampe, Philipp, Meyer-Almes, Franz-Josef, Sievers, Sonja, Neumann, Heinz
Published in Journal of medicinal chemistry (13.05.2021)
Published in Journal of medicinal chemistry (13.05.2021)
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Journal Article
Sense codon reassignment enables viral resistance and encoded polymer synthesis
Robertson, Wesley E., Funke, Louise F. H., de la Torre, Daniel, Fredens, Julius, Elliott, Thomas S., Spinck, Martin, Christova, Yonka, Cervettini, Daniele, Böge, Franz L., Liu, Kim C., Buse, Salvador, Maslen, Sarah, Salmond, George P. C., Chin, Jason W.
Published in Science (American Association for the Advancement of Science) (04.06.2021)
Published in Science (American Association for the Advancement of Science) (04.06.2021)
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Journal Article
Evolved, Selective Erasers of Distinct Lysine Acylations
Spinck, Martin, Neumann‐Staubitz, Petra, Ecke, Maria, Gasper, Raphael, Neumann, Heinz
Published in Angewandte Chemie International Edition (26.06.2020)
Published in Angewandte Chemie International Edition (26.06.2020)
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Journal Article
Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles
Spinck, Martin, Piedrafita, Carlos, Robertson, Wesley E. E., Elliott, Thomas S. S., Cervettini, Daniele, de la Torre, Daniel, Chin, Jason W. W.
Published in Nature chemistry (01.01.2023)
Published in Nature chemistry (01.01.2023)
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Journal Article
Continuous synthesis of E. coli genome sections and Mb-scale human DNA assembly
Zürcher, Jérôme F, Kleefeldt, Askar A, Funke, Louise F H, Birnbaum, Jakob, Fredens, Julius, Grazioli, Simona, Liu, Kim C, Spinck, Martin, Petris, Gianluca, Murat, Pierre, Rehm, Fabian B H, Sale, Julian E, Chin, Jason W
Published in Nature (London) (20.07.2023)
Published in Nature (London) (20.07.2023)
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Journal Article
Evolvierte, selektive Eraser für spezifische Lysinacylierungen
Spinck, Martin, Neumann‐Staubitz, Petra, Ecke, Maria, Gasper, Raphael, Neumann, Heinz
Published in Angewandte Chemie (26.06.2020)
Published in Angewandte Chemie (26.06.2020)
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Journal Article
METHODS OF EDITING NUCLEIC ACID SEQUENCES
FREDENS, Julius, KLEEFELDT, Askar A, FUNKE, Louise F H, BIRNBAUM, Jakob, ZURCHER, Jerome F, CHIN, Jason W, SPINCK, Martin
Year of Publication 11.09.2024
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Year of Publication 11.09.2024
Patent
METHODS OF EDITING NUCLEIC ACID SEQUENCES
FREDENS, Julius, KLEEFELDT, Askar A, FUNKE, Louise F H, BIRNBAUM, Jakob, ZURCHER, Jerome F, CHIN, Jason W, SPINCK, Martin
Year of Publication 28.03.2024
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Year of Publication 28.03.2024
Patent
METHODS OF EDITING NUCLEIC ACID SEQUENCES
BIRNBAUM, JAKOB, SPINCK, MARTIN, FREDENS, JULIUS, KLEEFELDT, ASKAR A, ZURCHER, JEROME F, FUNKE, LOUISE F. H, CHIN, JASON W
Year of Publication 11.05.2023
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Year of Publication 11.05.2023
Patent
METHODS OF EDITING NUCLEIC ACID SEQUENCES
FREDENS, Julius, KLEEFELDT, Askar A, FUNKE, Louise F H, BIRNBAUM, Jakob, ZURCHER, Jerome F, CHIN, Jason W, SPINCK, Martin
Year of Publication 11.05.2023
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Year of Publication 11.05.2023
Patent