The Evolution of Preclinical Alzheimer’s Disease: Implications for Prevention Trials
Sperling, Reisa, Mormino, Elizabeth, Johnson, Keith
Published in Neuron (Cambridge, Mass.) (05.11.2014)
Published in Neuron (Cambridge, Mass.) (05.11.2014)
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Journal Article
What Happens with the Circuit in Alzheimer's Disease in Mice and Humans?
Zott, Benedikt, Busche, Marc Aurel, Sperling, Reisa A, Konnerth, Arthur
Published in Annual review of neuroscience (08.07.2018)
Published in Annual review of neuroscience (08.07.2018)
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Journal Article
Preliminary Results of a Trial of Atabecestat in Preclinical Alzheimer’s Disease
Henley, David, Raghavan, Nandini, Sperling, Reisa, Aisen, Paul, Raman, Rema, Romano, Gary
Published in The New England journal of medicine (11.04.2019)
Published in The New England journal of medicine (11.04.2019)
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Journal Article
Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons
Donohue, Michael C, Sperling, Reisa A, Petersen, Ronald, Sun, Chung-Kai, Weiner, Michael W, Aisen, Paul S
Published in JAMA : the journal of the American Medical Association (13.06.2017)
Published in JAMA : the journal of the American Medical Association (13.06.2017)
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Journal Article
Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals
Sperling, Reisa A, Donohue, Michael C, Raman, Rema, Sun, Chung-Kai, Yaari, Roy, Holdridge, Karen, Siemers, Eric, Johnson, Keith A, Aisen, Paul S
Published in Archives of neurology (Chicago) (01.06.2020)
Published in Archives of neurology (Chicago) (01.06.2020)
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Journal Article
Longitudinal Association of Amyloid Beta and Anxious-Depressive Symptoms in Cognitively Normal Older Adults
Donovan, Nancy J, Locascio, Joseph J, Marshall, Gad A, Gatchel, Jennifer, Hanseeuw, Bernard J, Rentz, Dorene M, Johnson, Keith A, Sperling, Reisa A
Published in The American journal of psychiatry (01.06.2018)
Published in The American journal of psychiatry (01.06.2018)
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Journal Article
Preclinical Alzheimer disease—the challenges ahead
Sperling, Reisa A., Karlawish, Jason, Johnson, Keith A.
Published in Nature reviews. Neurology (2013)
Published in Nature reviews. Neurology (2013)
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Journal Article
Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease
Salloway, Stephen, Sperling, Reisa, Fox, Nick C, Blennow, Kaj, Klunk, William, Raskind, Murray, Sabbagh, Marwan, Honig, Lawrence S, Porsteinsson, Anton P, Ferris, Steven, Reichert, Marcel, Ketter, Nzeera, Nejadnik, Bijan, Guenzler, Volkmar, Miloslavsky, Maja, Wang, Daniel, Lu, Yuan, Lull, Julia, Tudor, Iulia Cristina, Liu, Enchi, Grundman, Michael, Yuen, Eric, Black, Ronald, Brashear, H. Robert
Published in The New England journal of medicine (23.01.2014)
Published in The New England journal of medicine (23.01.2014)
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Journal Article
The A4 study: stopping AD before symptoms begin?
Sperling, Reisa A, Rentz, Dorene M, Johnson, Keith A, Karlawish, Jason, Donohue, Michael, Salmon, David P, Aisen, Paul
Published in Science translational medicine (19.03.2014)
Published in Science translational medicine (19.03.2014)
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Journal Article
Trial of Solanezumab in Preclinical Alzheimer’s Disease
Sperling, Reisa A., Donohue, Michael C., Raman, Rema, Rafii, Michael S., Johnson, Keith, Masters, Colin L., van Dyck, Christopher H., Iwatsubo, Takeshi, Marshall, Gad A., Yaari, Roy, Mancini, Michele, Holdridge, Karen C., Case, Michael, Sims, John R., Aisen, Paul S.
Published in The New England journal of medicine (21.09.2023)
Published in The New England journal of medicine (21.09.2023)
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Journal Article
Testing the right target and right drug at the right stage
Sperling, Reisa A, Jack, Jr, Clifford R, Aisen, Paul S
Published in Science translational medicine (30.11.2011)
Published in Science translational medicine (30.11.2011)
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Journal Article
What Should the Goals Be for Diverse Recruitment in Alzheimer Clinical Trials?
Grill, Joshua D, Sperling, Reisa A, Raman, Rema
Published in Archives of neurology (Chicago) (01.11.2022)
Published in Archives of neurology (Chicago) (01.11.2022)
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Journal Article
The preclinical Alzheimer cognitive composite: measuring amyloid-related decline
Donohue, Michael C, Sperling, Reisa A, Salmon, David P, Rentz, Dorene M, Raman, Rema, Thomas, Ronald G, Weiner, Michael, Aisen, Paul S
Published in JAMA neurology (01.08.2014)
Published in JAMA neurology (01.08.2014)
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Journal Article
A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers
Jack, Jr, Clifford R, Bennett, David A, Blennow, Kaj, Carrillo, Maria C, Feldman, Howard H, Frisoni, Giovanni B, Hampel, Harald, Jagust, William J, Johnson, Keith A, Knopman, David S, Petersen, Ronald C, Scheltens, Philip, Sperling, Reisa A, Dubois, Bruno
Published in Neurology (02.08.2016)
Published in Neurology (02.08.2016)
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Journal Article
Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals
Jacobs, Heidi I. L., Hedden, Trey, Schultz, Aaron P., Sepulcre, Jorge, Perea, Rodrigo D., Amariglio, Rebecca E., Papp, Kathryn V., Rentz, Dorene M., Sperling, Reisa A., Johnson, Keith A.
Published in Nature neuroscience (01.03.2018)
Published in Nature neuroscience (01.03.2018)
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Journal Article
The case for low-level BACE1 inhibition for the prevention of Alzheimer disease
McDade, Eric, Voytyuk, Iryna, Aisen, Paul, Bateman, Randall J., Carrillo, Maria C., De Strooper, Bart, Haass, Christian, Reiman, Eric M., Sperling, Reisa, Tariot, Pierre N., Yan, Riqiang, Masters, Colin L., Vassar, Robert, Lichtenthaler, Stefan F.
Published in Nature reviews. Neurology (01.11.2021)
Published in Nature reviews. Neurology (01.11.2021)
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Journal Article