Expression and function of beta-glucuronidase in pancreatic cancer: potential role in drug targeting
Sperker, B, Werner, U, Mürdter, T E, Tekkaya, C, Fritz, P, Wacke, R, Adam, U, Gerken, M, Drewelow, B, Kroemer, H K
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.08.2000)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.08.2000)
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Journal Article
Verapamil regulates activity and mRNA-expression of human beta-glucuronidase in HepG2 cells
Grube, M, Kunert-Keil, C, Sperker, B, Kroemer, H K
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.12.2003)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.12.2003)
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Journal Article
The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol
Siegmund, Werner, Ludwig, Karen, Giessmann, Thomas, Dazert, Peter, Schroeder, Eike, Sperker, Bernhard, Warzok, Rolf, Kroemer, Heyo K, Cascorbi, Ingolf
Published in Clinical pharmacology and therapeutics (01.11.2002)
Published in Clinical pharmacology and therapeutics (01.11.2002)
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Quantitative immunohistochemical analysis of the glutathione S-transferase GSTM1: in situ phenotyping in archival material
FRITZ, P., SPERKER, B., MURDTER, T. E., SPATH, M., SCHWARZMANN, P., KROEMER, H. K., EICHELBAUM, M., KIVISTO, K. T.
Published in Xenobiotica (01.07.1999)
Published in Xenobiotica (01.07.1999)
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Elucidation of the mechanism enabling tumor selective prodrug monotherapy
BOSSLET, K, STRAUB, R, BLUMRICH, M, CZECH, J, GERKEN, M, SPERKER, B, KROEMER, H. K, GESSON, J.-P, KOCH, M, MONNERET, C
Published in Cancer research (Chicago, Ill.) (15.03.1998)
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Published in Cancer research (Chicago, Ill.) (15.03.1998)
Journal Article
Expression and Localization of P-glycoprotein in Human Heart: Effects of Cardiomyopathy
Meissner, Konrad, Sperker, Bernhard, Karsten, Christiane, zu Schwabedissen, Henriette Meyer, Seeland, Ute, Bohm, Michael, Bien, Sandra, Dazert, Peter, Kunert-Keil, Christiane, Vogelgesang, Silke, Warzok, Rolf, Siegmund, Werner, Cascorbi, Ingolf, Wendt, Michael, Kroemer, Heyo K
Published in The journal of histochemistry and cytochemistry (01.10.2002)
Published in The journal of histochemistry and cytochemistry (01.10.2002)
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Dose optimization of a doxorubicin prodrug (HMR 1826) in isolated perfused human lungs: low tumor pH promotes prodrug activation by beta-glucuronidase
Mürdter, Thomas E, Friedel, Godehard, Backman, Janne T, McClellan, Monika, Schick, Monika, Gerken, Manfred, Bosslet, Klaus, Fritz, Peter, Toomes, Heikki, Kroemer, Heyo K, Sperker, Bernhard
Published in The Journal of pharmacology and experimental therapeutics (01.04.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2002)
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Journal Article
Overexpression of glutathione S‐transferase A1‐1 in ECV 304 cells protects against busulfan mediated G2‐arrest and induces tissue factor expression
Ritter, Christoph A, Sperker, Bernhard, Grube, Markus, Dressel, Dana, Kunert‐Keil, Christiane, Kroemer, Heyo K
Published in British journal of pharmacology (01.12.2002)
Published in British journal of pharmacology (01.12.2002)
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Journal Article
Does pH 6 β-galactosidase activity indicate cell senescence?
Krishna, Devarakonda R, Sperker, Bernhard, Fritz, Peter, Klotz, Ulrich
Published in Mechanisms of ageing and development (30.08.1999)
Published in Mechanisms of ageing and development (30.08.1999)
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Journal Article
Effect of levothyroxine administration on intestinal P-glycoprotein expression: consequences for drug disposition
Siegmund, Werner, Altmannsberger, Stephan, Paneitz, Andrea, Hecker, Ute, Zschiesche, Michael, Franke, Gerd, Meng, Wieland, Warzok, Rolf, Schroeder, Eike, Sperker, Bernhard, Terhaag, Bernd, Cascorbi, Ingolf, Kroemer, Heyo K
Published in Clinical pharmacology and therapeutics (01.09.2002)
Published in Clinical pharmacology and therapeutics (01.09.2002)
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Journal Article
Verapamil regulates activity and mRNA-expression of human ?-glucuronidase in HepG2 cells
Grube, M., Kunert-Keil, C., Sperker, B., Kroemer, H. K.
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.12.2003)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.12.2003)
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Journal Article
Enhanced uptake of doxorubicin into bronchial carcinoma : β-glucuronidase mediates release of doxorubicin from a glucuronide prodrug (HMR 1826) at the tumor site
MÜRDTER, T. E, SPERKER, B, KROEMER, H. K, KIVISTÖ, K. T, MCCLELLAN, M, FRITZ, P, FRIEDEL, G, LINDER, A, BOSSLET, K, TOOMES, H, DIERKESMANN, R
Published in Cancer research (Chicago, Ill.) (15.06.1997)
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Published in Cancer research (Chicago, Ill.) (15.06.1997)
Journal Article
Busulfan induces activin A expression in vitro and in vivo: a possible link to venous occlusive disease
Dressel, Dana, Ritter, Christoph A, Sperker, Bernhard, Grube, Markus, Maier, Thorsten, Klingebiel, Thomas, Siegmund, Werner, Beck, James F, Kroemer, Heyo K
Published in Clinical pharmacology and therapeutics (01.09.2003)
Published in Clinical pharmacology and therapeutics (01.09.2003)
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Journal Article
Regulation of human beta-glucuronidase by A23187 and thapsigargin in the hepatoma cell line HepG2
Sperker, B, Tomkiewicz, C, Burk, O, Barouki, R, Kroemer, H K
Published in Molecular pharmacology (01.02.2001)
Published in Molecular pharmacology (01.02.2001)
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Journal Article
Verapamil decreases glucuronidase activity in the gut
Lötsch, Jörn, Sperker, Bernhard, Kroemer, Heyo K., Geisslinger, Gerd
Published in Biochemical pharmacology (15.04.2002)
Published in Biochemical pharmacology (15.04.2002)
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Journal Article
Interindividual variability in expression and activity of human beta-glucuronidase in liver and kidney: consequences for drug metabolism
Sperker, B, Mürdter, T E, Schick, M, Eckhardt, K, Bosslet, K, Kroemer, H K
Published in The Journal of pharmacology and experimental therapeutics (01.05.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.1997)
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