Microfluidic chip for culturing intestinal epithelial cell layers: Characterization and comparison of drug transport between dynamic and static models
Kulthong, Kornphimol, Duivenvoorde, Loes, Sun, Huiyi, Confederat, Samuel, Wu, Jiaqing, Spenkelink, Bert, de Haan, Laura, Marin, Victor, van der Zande, Meike, Bouwmeester, Hans
Published in Toxicology in vitro (01.06.2020)
Published in Toxicology in vitro (01.06.2020)
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Journal Article
Physiologically based kinetic modelling based prediction of in vivo rat and human acetylcholinesterase (AChE) inhibition upon exposure to diazinon
Zhao, Shensheng, Wesseling, Sebastiaan, Spenkelink, Bert, Rietjens, Ivonne M. C. M.
Published in Archives of toxicology (01.05.2021)
Published in Archives of toxicology (01.05.2021)
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Journal Article
Effects of Maerua subcordata (Gilg) DeWolf on electrophile-responsive element (EpRE)-mediated gene expression in vitro
Gebrelibanos Hiben, Mebrahtom, de Haan, Laura, Spenkelink, Bert, Wesseling, Sebas, Louisse, Jochem, Vervoort, Jacques, Rietjens, Ivonne M C M
Published in PloS one (2019)
Published in PloS one (2019)
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Journal Article
Induction of peroxisome proliferator activated receptor γ (PPARγ) mediated gene expression and inhibition of induced nitric oxide production by Maerua subcordata (Gilg) DeWolf
Hiben, Mebrahtom Gebrelibanos, de Haan, Laura, Spenkelink, Bert, Wesseling, Sebastiaan, Vervoort, Jacques, Rietjens, Ivonne M C M
Published in BMC complementary and alternative medicine (12.03.2020)
Published in BMC complementary and alternative medicine (12.03.2020)
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Journal Article
The pro-oxidant chemistry of the natural antioxidants vitamin C, vitamin E, carotenoids and flavonoids
Rietjens, Ivonne M.C.M., Boersma, Marelle G., Haan, Laura de, Spenkelink, Bert, Awad, Hanem M., Cnubben, Nicole H.P., van Zanden, Jelmer J., Woude, Hester van der, Alink, Gerrit M., Koeman, Jan H.
Published in Environmental toxicology and pharmacology (01.07.2002)
Published in Environmental toxicology and pharmacology (01.07.2002)
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Journal Article
Interplay between MRP Inhibition and Metabolism of MRP Inhibitors: The Case of Curcumin
Wortelboer, Heleen M, Usta, Mustafa, van der Velde, Astrid E, Boersma, Marelle G, Spenkelink, Bert, van Zanden, Jelmer J, Rietjens, Ivonne M. C. M, van Bladeren, Peter J, Cnubben, Nicole H. P
Published in Chemical research in toxicology (01.12.2003)
Published in Chemical research in toxicology (01.12.2003)
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Journal Article
Use of Physiologically Based Kinetic Modeling to Predict Rat Gut Microbial Metabolism of the Isoflavone Daidzein to S‐Equol and Its Consequences for ERα Activation
Wang, Qianrui, Spenkelink, Bert, Boonpawa, Rungnapa, Rietjens, Ivonne M. C. M., Beekmann, Karsten
Published in Molecular nutrition & food research (01.03.2020)
Published in Molecular nutrition & food research (01.03.2020)
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Journal Article
Physiologically Based Kinetic Modeling-Facilitated Reverse Dosimetry to Predict In Vivo Red Blood Cell Acetylcholinesterase Inhibition Following Exposure to Chlorpyrifos in the Caucasian and Chinese Population
Zhao, Shensheng, Kamelia, Lenny, Boonpawa, Rungnapa, Wesseling, Sebastiaan, Spenkelink, Bert, Rietjens, Ivonne M C M
Published in Toxicological sciences (01.09.2019)
Published in Toxicological sciences (01.09.2019)
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Journal Article
Front Cover: Use of Physiologically Based Kinetic Modeling to Predict Rat Gut Microbial Metabolism of the Isoflavone Daidzein to S‐Equol and Its Consequences for ERα Activation
Wang, Qianrui, Spenkelink, Bert, Boonpawa, Rungnapa, Rietjens, Ivonne M. C. M., Beekmann, Karsten
Published in Molecular nutrition & food research (01.03.2020)
Published in Molecular nutrition & food research (01.03.2020)
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Journal Article
Effects of Maerua subcordata -mediated gene expression in vitro
Gebrelibanos Hiben, Mebrahtom, de Haan, Laura, Spenkelink, Bert, Wesseling, Sebas, Louisse, Jochem, Vervoort, Jacques, Rietjens, Ivonne M.C.M
Published in PloS one (15.04.2019)
Published in PloS one (15.04.2019)
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Journal Article
Effects of Maerua subcordata
Gebrelibanos Hiben, Mebrahtom, de Haan, Laura, Spenkelink, Bert, Wesseling, Sebas, Louisse, Jochem, Vervoort, Jacques, Rietjens, Ivonne M.C.M
Published in PloS one (15.04.2019)
Published in PloS one (15.04.2019)
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Journal Article
Development of a Combined In Vitro Physiologically Based Kinetic (PBK) and Monte Carlo Modelling Approach to Predict Interindividual Human Variation in Phenol-Induced Developmental Toxicity
Strikwold, Marije, Spenkelink, Bert, Woutersen, Ruud A, Rietjens, Ivonne M C M, Punt, Ans
Published in Toxicological sciences (01.06.2017)
Published in Toxicological sciences (01.06.2017)
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Journal Article
Defining in vivo dose‐response curves for kidney DNA adduct formation of aristolochic acid I in rat, mouse and human by an in vitro and physiologically based kinetic modeling approach
Abdullah, Rozaini, Wesseling, Sebastiaan, Spenkelink, Bert, Louisse, Jochem, Punt, Ans, Rietjens, Ivonne M.C.M.
Published in Journal of applied toxicology (01.12.2020)
Published in Journal of applied toxicology (01.12.2020)
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Journal Article
Integrating in vitro data and physiologically based kinetic (PBK) modelling to assess the in vivo potential developmental toxicity of a series of phenols
Strikwold, Marije, Spenkelink, Bert, de Haan, Laura H. J., Woutersen, Ruud A., Punt, Ans, Rietjens, Ivonne M. C. M.
Published in Archives of toxicology (01.05.2017)
Published in Archives of toxicology (01.05.2017)
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Journal Article
The role of metabolism in the developmental toxicity of polycyclic aromatic hydrocarbon‐containing extracts of petroleum substances
Kamelia, Lenny, Haan, Laura, Spenkelink, Bert, Bruyneel, Ben, Ketelslegers, Hans B., Boogaard, Peter J., Rietjens, Ivonne M.C.M.
Published in Journal of applied toxicology (01.03.2020)
Published in Journal of applied toxicology (01.03.2020)
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Journal Article
Hazard assessment of Maerua subcordata (Gilg) DeWolf. for selected endpoints using a battery of in vitro tests
Gebrelibanos Hiben, Mebrahtom, Kamelia, Lenny, de Haan, Laura, Spenkelink, Bert, Wesseling, Sebastiaan, Vervoort, Jacques, Rietjens, Ivonne M.C.M.
Published in Journal of ethnopharmacology (15.09.2019)
Published in Journal of ethnopharmacology (15.09.2019)
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Journal Article