The Tamoxifen Metabolite, Endoxifen, Is a Potent Antiestrogen that Targets Estrogen Receptor α for Degradation in Breast Cancer Cells
XIANGLIN WU, HAWSE, John R, SUBRAMANIAM, Malayannan, GOETZ, Matthew P, INGLE, James N, SPELSBERG, Thomas C
Published in Cancer research (Chicago, Ill.) (01.03.2009)
Published in Cancer research (Chicago, Ill.) (01.03.2009)
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Journal Article
Endoxifen's molecular mechanisms of action are concentration dependent and different than that of other anti-estrogens
Hawse, John R, Subramaniam, Malayannan, Cicek, Muzaffer, Wu, Xianglin, Gingery, Anne, Grygo, Sarah B, Sun, Zhifu, Pitel, Kevin S, Lingle, Wilma L, Goetz, Matthew P, Ingle, James N, Spelsberg, Thomas C
Published in PloS one (28.01.2013)
Published in PloS one (28.01.2013)
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Kruppel-like factor 10 protects against acute viral myocarditis by negatively regulating cardiac MCP-1 expression
Yang, Jie, Zhang, Hongkai, Wang, Xuelian, Guo, Jing, Wei, Lin, Song, Yahui, Luo, Yuan, Zhao, YinXia, Subramaniam, Malayannan, Spelsberg, Thomas C., Wang, Lie, Xu, Wei, Li, Min
Published in Cellular & molecular immunology (01.09.2021)
Published in Cellular & molecular immunology (01.09.2021)
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Coprescription of Tamoxifen and Medications That Inhibit CYP2D6
SIDERAS, Kostandinos, INGLE, James N, AMES, Matthew M, LOPRINZI, Charles L, MRAZEK, David P, BLACK, John L, WEINSHILBOUM, Richard M, HAWSE, John R, SPELSBERG, Thomas C, GOETZ, Matthew P
Published in Journal of clinical oncology (01.06.2010)
Published in Journal of clinical oncology (01.06.2010)
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TGF-β inducible early gene 1 regulates osteoclast differentiation and survival by mediating the NFATc1, AKT, and MEK/ERK signaling pathways
Cicek, Muzaffer, Vrabel, Anne, Sturchio, Catherine, Pederson, Larry, Hawse, John R, Subramaniam, Malayannan, Spelsberg, Thomas C, Oursler, Merry Jo
Published in PloS one (14.03.2011)
Published in PloS one (14.03.2011)
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Journal Article
The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1
Spelsberg, Thomas, Elly, Chris, Subramaniam, Malayannan, Liu, Yun-Cai, Su, Jin, Venuprasad, K, Huang, Haining, Harada, Yousuke
Published in Nature immunology (01.03.2008)
Published in Nature immunology (01.03.2008)
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Journal Article
ERβ1: characterization, prognosis, and evaluation of treatment strategies in ERα-positive and -negative breast cancer
Reese, Jordan M, Suman, Vera J, Subramaniam, Malayannan, Wu, Xianglin, Negron, Vivian, Gingery, Anne, Pitel, Kevin S, Shah, Sejal S, Cunliffe, Heather E, McCullough, Ann E, Pockaj, Barbara A, Couch, Fergus J, Olson, Janet E, Reynolds, Carol, Lingle, Wilma L, Spelsberg, Thomas C, Goetz, Matthew P, Ingle, James N, Hawse, John R
Published in BMC cancer (07.10.2014)
Published in BMC cancer (07.10.2014)
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Estrogen receptor-beta sensitizes breast cancer cells to the anti-estrogenic actions of endoxifen
Wu, Xianglin, Subramaniam, Malayannan, Grygo, Sarah B, Sun, Zhifu, Negron, Vivian, Lingle, Wilma L, Goetz, Matthew P, Ingle, James N, Spelsberg, Thomas C, Hawse, John R
Published in Breast cancer research : BCR (10.03.2011)
Published in Breast cancer research : BCR (10.03.2011)
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Journal Article
Functional role of KLF10 in multiple disease processes
Subramaniam, Malayannan, Hawse, John R., Rajamannan, Nalini M., Ingle, James N., Spelsberg, Thomas C.
Published in BioFactors (Oxford) (01.01.2010)
Published in BioFactors (Oxford) (01.01.2010)
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Journal Article
TIEG1/KLF10 modulates Runx2 expression and activity in osteoblasts
Hawse, John R, Cicek, Muzaffer, Grygo, Sarah B, Bruinsma, Elizabeth S, Rajamannan, Nalini M, van Wijnen, Andre J, Lian, Jane B, Stein, Gary S, Oursler, Merry Jo, Subramaniam, Malayannan, Spelsberg, Thomas C
Published in PloS one (29.04.2011)
Published in PloS one (29.04.2011)
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Journal Article
Human Degenerative Valve Disease Is Associated With Up-Regulation of Low-Density Lipoprotein Receptor-Related Protein 5 Receptor-Mediated Bone Formation
Caira, Frank C., Stock, Stuart R., Gleason, Thomas G., McGee, Edwin C., Huang, Jie, Bonow, Robert O., Spelsberg, Thomas C., McCarthy, Patrick M., Rahimtoola, Shahbudin H., Rajamannan, Nalini M.
Published in Journal of the American College of Cardiology (18.04.2006)
Published in Journal of the American College of Cardiology (18.04.2006)
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Histone demethylase JARID1B/KDM5B is a corepressor of TIEG1/KLF10
Kim, Joanna, Shin, Sook, Subramaniam, Malayannan, Bruinsma, Elizabeth, Kim, Tae-Dong, Hawse, John R., Spelsberg, Thomas C., Janknecht, Ralf
Published in Biochemical and biophysical research communications (22.10.2010)
Published in Biochemical and biophysical research communications (22.10.2010)
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Journal Article
Development, characterization, and applications of a novel estrogen receptor beta monoclonal antibody
Wu, Xianglin, Subramaniam, Malayannan, Negron, Vivian, Cicek, Muzaffer, Reynolds, Carol, Lingle, Wilma L., Goetz, Matthew P., Ingle, James N., Spelsberg, Thomas C., Hawse, John R.
Published in Journal of cellular biochemistry (01.02.2012)
Published in Journal of cellular biochemistry (01.02.2012)
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Co-stimulation of the Bone-related Runx2 P1 Promoter in Mesenchymal Cells by SP1 and ETS Transcription Factors at Polymorphic Purine-rich DNA Sequences (Y-repeats)
Zhang, Ying, Hassan, Mohammad Q., Xie, Rong-Lin, Hawse, John R., Spelsberg, Thomas C., Montecino, Martin, Stein, Janet L., Lian, Jane B., van Wijnen, Andre J., Stein, Gary S.
Published in The Journal of biological chemistry (30.01.2009)
Published in The Journal of biological chemistry (30.01.2009)
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Journal Article
The effects of a novel hormonal breast cancer therapy, endoxifen, on the mouse skeleton
Gingery, Anne, Subramaniam, Malayannan, Pitel, Kevin S, Reese, Jordan M, Cicek, Muzaffer, Lindenmaier, Laurence B, Ingle, James N, Goetz, Matthew P, Turner, Russell T, Iwaniec, Urszula T, Spelsberg, Thomas C, Hawse, John R
Published in PloS one (22.05.2014)
Published in PloS one (22.05.2014)
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Journal Article
Noncanonical K27-linked polyubiquitination of TIEG1 regulates Foxp3 expression and tumor growth
Peng, Dong-Jun, Zeng, Minghui, Muromoto, Ryuta, Matsuda, Tadashi, Shimoda, Kazuya, Subramaniam, Malayannan, Spelsberg, Thomas C, Wei, Wei-Zen, Venuprasad, K
Published in The Journal of immunology (1950) (15.05.2011)
Published in The Journal of immunology (1950) (15.05.2011)
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Journal Article
Role of TIEG1 in biological processes and disease states
Subramaniam, Malayannan, Hawse, John R., Johnsen, Steven A., Spelsberg, Thomas C.
Published in Journal of cellular biochemistry (15.10.2007)
Published in Journal of cellular biochemistry (15.10.2007)
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Journal Article
Atorvastatin inhibits hypercholesterolemia-induced cellular proliferation and bone matrix production in the rabbit aortic valve
RAJAMANNAN, Nalini M, SUBRAMANIAM, Malayannan, SPRINGETT, Margaret, SEBO, Thomas C, NIEKRASZ, Marek, MCCONNELL, Joseph P, SINGH, Ravinder J, STONE, Neil J, BONOW, Robert O, SPELSBERG, Thomas C
Published in Circulation (New York, N.Y.) (04.06.2002)
Published in Circulation (New York, N.Y.) (04.06.2002)
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