Effect of selective IK,ACh inhibition by XAF‐1407 in an equine model of tachypacing‐induced persistent atrial fibrillation
Fenner, Merle Friederike, Carstensen, Helena, Dalgas Nissen, Sarah, Melis Hesselkilde, Eva, Scott Lunddahl, Christine, Adler Hess Jensen, Maja, Loft‐Andersen, Ameli Victoria, Sattler, Stefan Michael, Platonov, Pyotr, El‐Haou, Said, Jackson, Claire, Tang, Raymond, Kirby, Robert, Ford, John, Schotten, Ulrich, Milnes, James, Svane Sørensen, Ulrik, Jespersen, Thomas, Buhl, Rikke
Published in British journal of pharmacology (01.08.2020)
Published in British journal of pharmacology (01.08.2020)
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Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses
Haugaard, Maria Mathilde, DVM, FHRS, Hesselkilde, Eva Zander, DVM, Pehrson, Steen, MD, PhD, Carstensen, Helena, DVM, Flethøj, Mette, DVM, Præstegaard, Kirstine Færgemand, DVM, Sørensen, Ulrik Svane, PhD, Diness, Jonas Goldin, PhD, FHRS, Grunnet, Morten, PhD, FHRS, Buhl, Rikke, DVM, PhD, Jespersen, Thomas, PhD, FHRS
Published in Heart rhythm (01.04.2015)
Published in Heart rhythm (01.04.2015)
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A phase 1 trial of AP30663, a KCa2 channel inhibitor in development for conversion of atrial fibrillation
Yfanti, Christina, Vestbjerg, Birgitte, Van't Westende, Juliette, Edvardsson, Nils, Monfort, Laia Meseguer, Olesen, Morten Salling, Bentzen, Bo Hjorth, Grunnet, Morten, Eveleens Maarse, Boukje C, Diness, Jonas Goldin, Kemme, Michiel J B, Sørensen, Ulrik, Moerland, Matthijs, van Esdonk, Michiel J, Klaassen, Erica S, Gal, Pim, Holst, Anders G
Published in British journal of clinical pharmacology (01.04.2024)
Published in British journal of clinical pharmacology (01.04.2024)
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Inhibition of Small-Conductance Calcium-Activated Potassium Current ( I K,Ca ) Leads to Differential Atrial Electrophysiological Effects in a Horse Model of Persistent Atrial Fibrillation
Fenner, Merle Friederike, Gatta, Giulia, Sattler, Stefan, Kuiper, Marion, Hesselkilde, Eva Melis, Adler, Ditte M T, Smerup, Morten, Schotten, Ulrich, Sørensen, Ulrik, Diness, Jonas Goldin, Jespersen, Thomas, Verheule, Sander, Van Hunnik, Arne, Buhl, Rikke
Published in Frontiers in physiology (09.02.2021)
Published in Frontiers in physiology (09.02.2021)
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Increased fibroblast accumulation in the equine heart following persistent atrial fibrillation
Saljic, Arnela, Friederike Fenner, Merle, Winters, Joris, Flethøj, Mette, Eggert Eggertsen, Caroline, Carstensen, Helena, Dalgas Nissen, Sarah, Melis Hesselkilde, Eva, van Hunnik, Arne, Schotten, Ulrich, Sørensen, Ulrik, Jespersen, Thomas, Verheule, Sander, Buhl, Rikke
Published in International journal of cardiology. Heart & vasculature (01.08.2021)
Published in International journal of cardiology. Heart & vasculature (01.08.2021)
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Inhibition of the KCa2 potassium channel in atrial fibrillation: a randomized phase 2 trial
Holst, Anders G, Tomcsányi, János, Vestbjerg, Birgitte, Grunnet, Morten, Sørensen, Ulrik S, Diness, Jonas G, Bentzen, Bo H, Edvardsson, Nils, Hohnloser, Stefan H, Bhatt, Deepak L, Dorian, Paul
Published in Nature medicine (01.01.2024)
Published in Nature medicine (01.01.2024)
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Effective termination of atrial fibrillation by SK channel inhibition is associated with a sudden organization of fibrillatory conduction
Gatta, Giulia, Sobota, Vladimir, Citerni, Carlotta, Diness, Jonas Goldin, Sørensen, Ulrik S, Jespersen, Thomas, Bentzen, Bo Hjorth, Zeemering, Stef, Kuiper, Marion, Verheule, Sander, Schotten, Ulrich, van Hunnik, Arne
Published in Europace (London, England) (08.11.2021)
Published in Europace (London, England) (08.11.2021)
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Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Diness, Jonas Goldin, Skibsbye, Lasse, Simó-Vicens, Rafel, Santos, Joana Larupa, Lundegaard, Pia, Citerni, Carlotta, Sauter, Daniel Rafael Peter, Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, Ulrik S, Jespersen, Thomas, Grunnet, Morten, Bentzen, Bo Hjorth
Published in Circulation. Arrhythmia and electrophysiology (01.10.2017)
Published in Circulation. Arrhythmia and electrophysiology (01.10.2017)
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Analysis of drug-induced and spontaneous cardioversions reveals similar patterns leading to termination of atrial fibrillation
van Hunnik, Arne, Sobota, Vladimír, Zeemering, Stef, Opacic, Dragan, Scaf, Billy, D'Alessandro, Elisa, Oyaert, Karel, Kuiper, Marion, Diness, Jonas G, Sørensen, Ulrik S, Milnes, James T, van der Heyden, Marcel A G, Jespersen, Thomas, Schotten, Ulrich, Verheule, Sander
Published in Frontiers in physiology (18.07.2024)
Published in Frontiers in physiology (18.07.2024)
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Sexual satisfaction and its predictors in patients with advanced cancer and their family caregivers in six European countries: Baseline data from the DIAdIC study
Matthys, Orphé, Dierickx, Sigrid, Van Goethem, Vincent, Deliens, Luc, Lapeire, Lore, De Pauw, Aglaja, Hudson, Peter, Vulsteke, Christof, Geboes, Karen, De Waele, Stefanie, Spoormans, Isabelle, Di Leo, Silvia, Guberti, Monica, Schmidt, Ulrik Sørensen, Scott, David, Harding, Richard, Witkamp, Erica, Connolly, Michael, De Vleminck, Aline, Cohen, Joachim, Eecloo, Kim, Renard, Vincent, De Groote, Jurgen, Lobbestael, Nele, Pappot, Helle, Sengeløv, Lisa, Grønvold, Mogens, Bristowe, Katherine, Heide, Agnes, Wel, Maaike, Turola, Elena, Puglisi, Chiara, Sforacchi, Federica, Soffientini, Valeria, Tortella, Stefania, Zini, Silvia, Brazil, Kevin, Reid, Joanne, Prue, Gillian, Normand, Charles, May, Peter, Guerin, Suzanne, D’Alton, Paul, Pilch, Monika, Larkin, Phil
Published in Psycho-oncology (Chichester, England) (01.06.2024)
Published in Psycho-oncology (Chichester, England) (01.06.2024)
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A new negative allosteric modulator, AP14145, for the study of small conductance calcium‐activated potassium (KCa2) channels
Simó‐Vicens, Rafel, Kirchhoff, Jeppe E, Dolce, Bernardo, Abildgaard, Lea, Speerschneider, Tobias, Sørensen, Ulrik S, Grunnet, Morten, Diness, Jonas G, Bentzen, Bo H
Published in British journal of pharmacology (01.12.2017)
Published in British journal of pharmacology (01.12.2017)
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The KCa2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs
Diness, Jonas Goldin, Kirchhoff, Jeppe Egedal, Speerschneider, Tobias, Abildgaard, Lea, Edvardsson, Nils, Sørensen, Ulrik S., Grunnet, Morten, Bentzen, Bo Hjorth
Published in Frontiers in pharmacology (28.02.2020)
Published in Frontiers in pharmacology (28.02.2020)
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Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man
Bentzen, Bo Hjorth, Bomholtz, Sofia Hammami, Simó-Vicens, Rafel, Folkersen, Lasse, Abildgaard, Lea, Speerschneider, Tobias, Muthukumarasamy, Kalai Mangai, Edvardsson, Nils, Sørensen, Ulrik S, Grunnet, Morten, Diness, Jonas Goldin
Published in Frontiers in pharmacology (06.05.2020)
Published in Frontiers in pharmacology (06.05.2020)
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Effects on Atrial Fibrillation in Aged Hypertensive Rats by Ca2+-Activated K+ Channel Inhibition
Diness, Jonas G, Skibsbye, Lasse, Jespersen, Thomas, Bartels, Emil D, Sørensen, Ulrik S, Hansen, Rie S, Grunnet, Morten
Published in Hypertension (Dallas, Tex. 1979) (01.06.2011)
Published in Hypertension (Dallas, Tex. 1979) (01.06.2011)
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Inhibition of Small-Conductance Ca2+-Activated K+ Channels Terminates and Protects Against Atrial Fibrillation
Diness, Jonas Goldin, Sørensen, Ulrik S, Nissen, Jakob Dahl, Al-Shahib, Baha, Jespersen, Thomas, Grunnet, Morten, Hansen, Rie Schultz
Published in Circulation. Arrhythmia and electrophysiology (01.08.2010)
Published in Circulation. Arrhythmia and electrophysiology (01.08.2010)
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Arrhythmia development during inhibition of small-conductance calcium-activated potassium channels in acute myocardial infarction in a porcine model
Lubberding, Anniek F, Sattler, Stefan M, Grunnet, Morten, Sørensen, Ulrik S, Tfelt-Hansen, Jacob, Jespersen, Thomas
Published in Europace (London, England) (01.10.2019)
Published in Europace (London, England) (01.10.2019)
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Effects on atrial fibrillation in aged hypertensive rats by Ca(2+)-activated K(+) channel inhibition
Diness, Jonas G, Skibsbye, Lasse, Jespersen, Thomas, Bartels, Emil D, Sørensen, Ulrik S, Hansen, Rie S, Grunnet, Morten
Published in Hypertension (Dallas, Tex. 1979) (01.06.2011)
Published in Hypertension (Dallas, Tex. 1979) (01.06.2011)
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