A Blood-Brain-Barrier-Penetrating Anti-human Transferrin Receptor Antibody Fusion Protein for Neuronopathic Mucopolysaccharidosis II
Sonoda, Hiroyuki, Morimoto, Hideto, Yoden, Eiji, Koshimura, Yuri, Kinoshita, Masafumi, Golovina, Galina, Takagi, Haruna, Yamamoto, Ryuji, Minami, Kohtaro, Mizoguchi, Akira, Tachibana, Katsuhiko, Hirato, Tohru, Takahashi, Kenichi
Published in Molecular therapy (02.05.2018)
Published in Molecular therapy (02.05.2018)
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Clearance of heparan sulfate in the brain prevents neurodegeneration and neurocognitive impairment in MPS II mice
Morimoto, Hideto, Kida, Sachiho, Yoden, Eiji, Kinoshita, Masafumi, Tanaka, Noboru, Yamamoto, Ryuji, Koshimura, Yuri, Takagi, Haruna, Takahashi, Kenichi, Hirato, Tohru, Minami, Kohtaro, Sonoda, Hiroyuki
Published in Molecular therapy (05.05.2021)
Published in Molecular therapy (05.05.2021)
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Journal Article
Pathogenic Roles of Heparan Sulfate and Its Use as a Biomarker in Mucopolysaccharidoses
Minami, Kohtaro, Morimoto, Hideto, Morioka, Hiroki, Imakiire, Atsushi, Kinoshita, Masafumi, Yamamoto, Ryuji, Hirato, Tohru, Sonoda, Hiroyuki
Published in International journal of molecular sciences (03.10.2022)
Published in International journal of molecular sciences (03.10.2022)
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Journal Article
Enzyme Replacement Therapy with Pabinafusp Alfa for Neuronopathic Mucopolysaccharidosis II: An Integrated Analysis of Preclinical and Clinical Data
Giugliani, Roberto, Martins, Ana Maria, Okuyama, Torayuki, Eto, Yoshikatsu, Sakai, Norio, Nakamura, Kimitoshi, Morimoto, Hideto, Minami, Kohtaro, Yamamoto, Tatsuyoshi, Yamaoka, Mariko, Ikeda, Toshiaki, So, Sairei, Tanizawa, Kazunori, Sonoda, Hiroyuki, Schmidt, Mathias, Sato, Yuji
Published in International journal of molecular sciences (10.10.2021)
Published in International journal of molecular sciences (10.10.2021)
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Journal Article
Dose-dependent effects of a brain-penetrating iduronate-2-sulfatase on neurobehavioral impairments in mucopolysaccharidosis II mice
Morimoto, Hideto, Morioka, Hiroki, Imakiire, Atsushi, Yamamoto, Ryuji, Hirato, Tohru, Sonoda, Hiroyuki, Minami, Kohtaro
Published in Molecular therapy. Methods & clinical development (09.06.2022)
Published in Molecular therapy. Methods & clinical development (09.06.2022)
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Journal Article
The retinol‐retinoic acid metabolic pathway is impaired in the lumbar spine of a rat model of congenital kyphoscoliosis
Sonoda, Hiroyuki, Iizuka, Haku, Ishiwata, Sho, Tsunoda, Daisuke, Abe, Masako, Takagishi, Kenji, Chikuda, Hirotaka, Koibuchi, Noriyuki, Shimokawa, Noriaki
Published in Journal of cellular biochemistry (01.09.2019)
Published in Journal of cellular biochemistry (01.09.2019)
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Treatment of Neuronopathic Mucopolysaccharidoses with Blood–Brain Barrier-Crossing Enzymes: Clinical Application of Receptor-Mediated Transcytosis
Sonoda, Hiroyuki, Takahashi, Kenichi, Minami, Kohtaro, Hirato, Toru, Yamamoto, Tatsuyoshi, So, Sairei, Tanizawa, Kazunori, Schmidt, Mathias, Sato, Yuji
Published in Pharmaceutics (11.06.2022)
Published in Pharmaceutics (11.06.2022)
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Correction of central nervous system deficits in the mouse model of Hunter syndrome by recombinant iduronate 2-sulfatase crossing the blood-brain barrier
Sonoda, Hiroyuki, Morimoto, Hideto, Koshimura, Yuri, Kinoshita, Masafumi
Published in Molecular genetics and metabolism (01.01.2017)
Published in Molecular genetics and metabolism (01.01.2017)
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Journal Article
Recurrent lumbar-origin osteoblastoma treated with multiple surgery and carbon ion radiotherapy: a case report
Honda, Akira, Iizuka, Yoichi, Imai, Reiko, Nishinome, Masahiro, Hirato, Junko, Koshi, Hiromi, Mieda, Tokue, Sonoda, Hiroyuki, Ishiwata, Sho, Kakuta, Yohei, Tajika, Tsuyoshi, Chikuda, Hirotaka
Published in BMC musculoskeletal disorders (22.05.2020)
Published in BMC musculoskeletal disorders (22.05.2020)
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Journal Article
Enzyme replacement with transferrin receptor-targeted α-L-iduronidase rescues brain pathology in mucopolysaccharidosis I mice
Kida, Sachiho, Koshimura, Yuri, Yoden, Eiji, Yoshioka, Aya, Morimoto, Hideto, Imakiire, Atsushi, Tanaka, Noboru, Tanaka, Satowa, Mori, Ayaka, Ito, Jun, Inoue, Asuka, Yamamoto, Ryuji, Minami, Kohtaro, Hirato, Tohru, Takahashi, Kenichi, Sonoda, Hiroyuki
Published in Molecular therapy. Methods & clinical development (08.06.2023)
Published in Molecular therapy. Methods & clinical development (08.06.2023)
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Journal Article
Treatment of CLN1 disease with a blood-brain barrier penetrating lysosomal enzyme
Hahn, Andreas, Sato, Yuji, Ikeda, Toshiaki, Sonoda, Hiroyuki, Schmidt, Mathias, Pfrimmer, Charlotte, Boado, Ruben J., Pardridge, William M.
Published in Molecular genetics and metabolism reports (01.12.2022)
Published in Molecular genetics and metabolism reports (01.12.2022)
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Journal Article
Divergent developmental trajectories in two siblings with neuropathic mucopolysaccharidosis type II (Hunter syndrome) receiving conventional and novel enzyme replacement therapies: A case report
Tomita, Kazuyoshi, Okamoto, Shungo, Seto, Toshiyuki, Hamazaki, Takashi, So, Sairei, Yamamoto, Tatsuyoshi, Tanizawa, Kazunori, Sonoda, Hiroyuki, Sato, Yuji
Published in JIMD reports (01.11.2021)
Published in JIMD reports (01.11.2021)
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Journal Article
Production of single-chain Fv–Fc fusion protein in stably transformed insect cells
Sonoda, Hiroyuki, Kumada, Yoichi, Katsuda, Tomohisa, Yamaji, Hideki
Published in Biochemical engineering journal (15.08.2012)
Published in Biochemical engineering journal (15.08.2012)
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Functional expression of single-chain Fv antibody in the cytoplasm of Escherichia coli by thioredoxin fusion and co-expression of molecular chaperones
Sonoda, Hiroyuki, Kumada, Yoichi, Katsuda, Tomohisa, Yamaji, Hideki
Published in Protein expression and purification (01.04.2010)
Published in Protein expression and purification (01.04.2010)
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Transdural cauda equina herniation after uneventful lumbar surgery: A case report and review of the literature
Kakuta, Yohei, Iizuka, Yoichi, Mieda, Tokue, Sonoda, Hiroyuki, Ishiwata, Sho, Honda, Akira, Tsunoda, Daisuke, Takasawa, Eiji, Tajika, Tsuyoshi, Chikuda, Hirotaka
Published in Interdisciplinary neurosurgery : Advanced techniques and case management (01.06.2021)
Published in Interdisciplinary neurosurgery : Advanced techniques and case management (01.06.2021)
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Journal Article
Upregulated miR-224-5p suppresses osteoblast differentiation by increasing the expression of Pai-1 in the lumbar spine of a rat model of congenital kyphoscoliosis
Ishiwata, Sho, Iizuka, Haku, Sonoda, Hiroyuki, Tsunoda, Daisuke, Tajika, Yuki, Chikuda, Hirotaka, Koibuchi, Noriyuki, Shimokawa, Noriaki
Published in Molecular and cellular biochemistry (01.12.2020)
Published in Molecular and cellular biochemistry (01.12.2020)
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