Amelioration of sepsis by TIE2 activation-induced vascular protection
Han, Sangyeul, Lee, Seung-Jun, Kim, Kyung Eun, Lee, Hyo Seon, Oh, Nuri, Park, Inwon, Ko, Eun, Oh, Seung Ja, Lee, Yoon-Sook, Kim, David, Lee, Seungjoo, Lee, Dae Hyun, Lee, Kwang-Hoon, Chae, Su Young, Lee, Jung-Hoon, Kim, Su-Jin, Kim, Hyung-Chan, Kim, Seokkyun, Kim, Sung Hyun, Kim, Chungho, Nakaoka, Yoshikazu, He, Yulong, Augustin, Hellmut G, Hu, Junhao, Song, Paul H, Kim, Yong-In, Kim, Pilhan, Kim, Injune, Koh, Gou Young
Published in Science translational medicine (20.04.2016)
Published in Science translational medicine (20.04.2016)
Get more information
Journal Article
MET Signaling Regulates Glioblastoma Stem Cells
KYEUNG MIN JOO, JIN, Juyoun, KIM, Hyunggee, HOJUNSEOL, KONG, Doo-Sik, LEE, Jung-Ii, RICH, Jeremy N, LEE, Jeongwu, NAM, Do-Hyun, KIM, Eunhee, KANG HO KIM, KIM, Yonghyun, BONG GU KANG, KANG, Youn-Jung, LATHIA, Justin D, KWANG HO CHEONG, SONG, Paul H
Published in Cancer research (Chicago, Ill.) (01.08.2012)
Published in Cancer research (Chicago, Ill.) (01.08.2012)
Get full text
Journal Article
A new anti-c-met antibody selected by a mechanism-based dual-screening method: Therapeutic potential in cancer
Oh, Y.M., Samsung Advanced Institute of Technology, Yongin, Republic of Korea, Song, Y.J., Samsung Advanced Institute of Technology, Yongin, Republic of Korea, Lee, S.B., Samsung Advanced Institute of Technology, Yongin, Republic of Korea, Jeong, Y.J., Samsung Advanced Institute of Technology, Yongin, Republic of Korea, Kim, B.G., Samsung Advanced Institute of Technology, Yongin, Republic of Korea, Kim, G.W., Samsung Advanced Institute of Technology, Yongin, Republic of Korea, Kim, K.E., Samsung Advanced Institute of Technology, Yongin, Republic of Korea, Lee, J.M., Samsung Advanced Institute of Technology, Yongin, Republic of Korea, Cho, M.Y., Samsung Advanced Institute of Technology, Yongin, Republic of Korea, Choi, J.H., Samsung Advanced Institute of Technology, Yongin, Republic of Korea, Nam, D.H., Samsung Biomedical Research Institute, Samsung Medical Center, Seoul, Republic of Korea, Song, Paul H, Samsung Advanced Institute of Technology, Yongin, Republic of Korea, Cheong, K.H., Samsung Advanced Institute of Technology, Yongin, Republic of Korea, Kim, K.A., Samsung Advanced Institute of Technology, Yongin, Republic of Korea
Published in Molecules and cells (01.12.2012)
Published in Molecules and cells (01.12.2012)
Get full text
Journal Article
USP8 modulates ubiquitination of LRIG1 for Met degradation
Oh, Young Mi, Lee, Saet Byoul, Choi, Jaehyun, Suh, Hye-Young, Shim, Seonhui, Song, Yun-Jeong, Kim, Bogyou, Lee, Ji Min, Oh, Seung Ja, Jeong, Yunju, Cheong, Kwang Ho, Song, Paul H., Kim, Kyung-Ah
Published in Scientific reports (15.05.2014)
Published in Scientific reports (15.05.2014)
Get full text
Journal Article
Gln-362 of Angiopoietin-2 Mediates Migration of Tumor and Endothelial Cells through Association with α5β1 Integrin
Lee, Hyo Seon, Oh, Seung Ja, Lee, Kwang-Hoon, Lee, Yoon-Sook, Ko, Eun, Kim, Kyung Eun, Kim, Hyung-chan, Kim, Seokkyun, Song, Paul H., Kim, Yong-In, Kim, Chungho, Han, Sangyeul
Published in The Journal of biological chemistry (07.11.2014)
Published in The Journal of biological chemistry (07.11.2014)
Get full text
Journal Article
USP8 modulates ubiquitination of LRIG1 for Met degradation
Oh, Young Mi, Lee, Saet Byoul, Choi, Jaehyun, Suh, Hye-Young, Shim, Seonhui, Song, Yun-Jeong, Kim, Bogyou, Lee, Ji Min, Oh, Seung Ja, Jeong, Yunju, Cheong, Kwang Ho, Song, Paul H, Kim, Kyung-Ah
Published in Scientific reports (15.05.2014)
Published in Scientific reports (15.05.2014)
Get full text
Journal Article
Protein grafting of p53TAD onto a leucine zipper scaffold generates a potent HDM dual inhibitor
Lee, Jung-Hoon, Kang, Eunji, Lee, Jungmin, Kim, Jungmin, Lee, Kyoung Hu, Han, Jieun, Kang, Hye Yoon, Ahn, Soshin, Oh, Youngmi, Shin, Dongkyu, Hur, Kyeyeon, Chae, Su Young, Song, Paul H, Kim, Yong-In, Park, Jae Chan, Lee, Jae Il
Published in Nature communications (07.05.2014)
Published in Nature communications (07.05.2014)
Get full text
Journal Article
엑사테칸 유도체, 링커-페이로드 및 이의 접합체
HU MINGYU, ZHANG TONY YANTAO, SONG PAUL H, CHEN GUANGMING, ZHONG BOYU, QIN GANG
Year of Publication 27.11.2023
Get full text
Year of Publication 27.11.2023
Patent
Abstract 3123: Preclinical characterization of AMB302/GQ1011, a first-in-class FGFR3 antibody-drug conjugate (ADC) with topoisomerase 1 inhibitor against diverse FGFR3 overexpression or alteration
Min, Byeongkwi, Lee, Sunghyun, Jung, Wonsik, Wang, Lina, Sun, Yajun, Kim, Hyejin, Her, Nam-Gu, Song, Paul H., Qin, Gang, Nam, Do-Hyun
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
Abstract 7168: PBI-410 (GQ1010), A novel Trop-2-targeted ADC demonstrates a favorable safety and toxicokinetic profile in multiple preclinical assessments
Sun, Yajun, Reddy, Vijayapal, Kulanthaivel, Palaniappan, Feng, Yanwen, Zhao, Jie, Chi, Zhiyan, Wang, Junhao, Shi, Lili, Qin, Gang, Song, Paul H.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
Abstract 2114: Enhancing therapeutic strategies for osimertinib-resistant EGFR-mutant NSCLC: A HER3 dual-payload ADC (dpADC) with topoisomerase I and EGFR tyrosine kinase inhibitor
Wang, Lina, Xiong, Meijun, Gao, Xinju, Zhou, Chengang, Han, Yu, Li, Yanchun, Wang, Junhao, Shi, Lili, Qin, Gang, Song, Paul H.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
Abstract 2124: Validation of the intelligent glycotransferase-dependent conjugation (iGDC) platform: A groundbreaking approach for next-generation HER2-targeting ADC GQ1012 with enhanced druggability, potency, and safety
Xiong, Meijun, Mu, Zengyan, Xu, Meiling, Liu, Chong, Dai, Bo, Wang, Junhao, Gao, Xinju, Shi, Lili, Song, Paul H., Qin, Gang
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
Abstract CT178: GQ1001: A next generation HER2-targeting ADC that exhibits promising early clinical efficacy with excellent tolerance in a multi-center, Phase Ia study
Lemech, Charlotte, Zhou, Chenfei, Zhan, Xianbao, Shi, Yan, Liu, Jieqiong, Piha-Paul, Sarina A, Richardson, Gary, Qin, Gang, Song, Paul H., Shi, Lili, Sun, Yajun, Xia, Yi
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Get full text
Journal Article
Abstract 1549: Preclinical characterization of GQ1010, a next generation Trop2 ADC with the best-in-class potential against diverse Trop2+ solid tumors
Sun, Yajun, Hu, Mingyu, Lv, Cao, Si, Yu, Liu, Xiao, Gao, Xinju, Yang, Dong, Chen, Guangming, Zhong, Boyu, Zhang, Tony, Shi, Lili, Qin, Gang, Song, Paul H.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Get full text
Journal Article
Abstract 2640: An innovative site-specific dual-payload antibody drug conjugate (dpADC) combining a novel Topo1 inhibitor and an immune agonist delivers a strong immunogenic cell death (ICD) and antitumor response in vitro and in vivo
Xiong, Meijun, Fan, Beibei, Gao, Xinju, Sun, Yajun, Lv, Cao, Si, Yu, Liu, Xiao, Shi, Lili, Song, Paul H., Qin, Gang
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Get full text
Journal Article
Abstract 2702: GQ1001 is a next generation HER2-targeting ADC with excellent druggability, safety and potency
Huang, Lei, Shi, Lili, Sun, Yajun, Lv, Cao, Gong, Chengcheng, Liu, Chong, Yang, Jun, Jiang, Lu, Yuan, Jinduo, Li, Xuesong, Hu, Mingyu, Gao, Xinju, Si, Yu, Yang, Hui, Shi, Yan, Yang, Bo, Song, Paul H., Qin, Gang, Wang, Biyun
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Get full text
Journal Article
Synthetic lethal screening reveals FGFR as one of the combinatorial targets to overcome resistance to Met-targeted therapy
Kim, B, Wang, S, Lee, J M, Jeong, Y, Ahn, T, Son, D-S, Park, H W, Yoo, H-s, Song, Y-J, Lee, E, Oh, Y M, Lee, S B, Choi, J, Murray, J C, Zhou, Y, Song, P H, Kim, K-A, Weiner, L M
Published in Oncogene (26.02.2015)
Published in Oncogene (26.02.2015)
Get full text
Journal Article