Activation of the Cannabinoid Type-1 Receptor Mediates the Anticonvulsant Properties of Cannabinoids in the Hippocampal Neuronal Culture Models of Acquired Epilepsy and Status Epilepticus
Blair, Robert E, Deshpande, Laxmikant S, Sombati, Sompong, Falenski, Katherine W, Martin, Billy R, DeLorenzo, Robert J
Published in The Journal of pharmacology and experimental therapeutics (01.06.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2006)
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Time course and mechanism of hippocampal neuronal death in an in vitro model of status epilepticus: Role of NMDA receptor activation and NMDA dependent calcium entry
Deshpande, Laxmikant S., Lou, Jeffrey K., Mian, Ali, Blair, Robert E., Sombati, Sompong, Attkisson, Elisa, DeLorenzo, Robert J.
Published in European journal of pharmacology (31.03.2008)
Published in European journal of pharmacology (31.03.2008)
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Journal Article
Prolonged exposure to WIN55,212-2 causes downregulation of the CB1 receptor and the development of tolerance to its anticonvulsant effects in the hippocampal neuronal culture model of acquired epilepsy
Blair, Robert E., Deshpande, Laxmikant S., Sombati, Sompong, Elphick, Maurice R., Martin, Billy R., DeLorenzo, Robert J.
Published in Neuropharmacology (01.09.2009)
Published in Neuropharmacology (01.09.2009)
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Journal Article
Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy
Deshpande, Laxmikant S., Sombati, Sompong, Blair, Robert E., Carter, Dawn S., Martin, Billy R., DeLorenzo, Robert J.
Published in Neuroscience letters (03.01.2007)
Published in Neuroscience letters (03.01.2007)
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Journal Article
Evidence That Injury-Induced Changes in Hippocampal Neuronal Calcium Dynamics during Epileptogenesis Cause Acquired Epilepsy
Raza, Mohsin, Blair, Robert E., Sombati, Sompong, Carter, Dawn S., Deshpande, Laxmikant S., DeLorenzo, Robert J., Siekevitz, Philip
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2004)
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Characterization of spontaneous recurrent epileptiform discharges in hippocampal–entorhinal cortical slices prepared from chronic epileptic animals
Carter, Dawn S, Deshpande, Laxmikant S, Rafiq, Azhar, Sombati, Sompong, DeLorenzo, Robert J
Published in Seizure (London, England) (01.04.2011)
Published in Seizure (London, England) (01.04.2011)
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Epileptogenesis Causes Acute and Chronic Increases in GABAA Receptor Endocytosis That Contributes to the Induction and Maintenance of Seizures in the Hippocampal Culture Model of Acquired Epilepsy
Blair, Robert E, Sombati, Sompong, Lawrence, David C, McCay, Brendan D, DeLorenzo, Robert J
Published in The Journal of pharmacology and experimental therapeutics (01.09.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2004)
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Prolonged Activation of the N-methyl-D-Aspartate receptor-Ca2+ Transduction Pathway Causes Spontaneous Recurrent Epileptiform Discharges in Hippocampal Neurons in Culture
DeLorenzo, Robert J., Pal, Shubhro, Sombati, Sompong
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.1998)
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Activation of a Novel Injury-Induced Calcium-Permeable Channel That Plays a Key Role in Causing Extended Neuronal Depolarization and Initiating Neuronal Death in Excitotoxic Neuronal Injury
Deshpande, Laxmikant S, Limbrick, Jr, David D, Sombati, Sompong, DeLorenzo, Robert J
Published in The Journal of pharmacology and experimental therapeutics (01.08.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2007)
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Journal Article
Altered Calcium/Calmodulin Kinase II Activity Changes Calcium Homeostasis That Underlies Epileptiform Activity in Hippocampal Neurons in Culture
Carter, Dawn S, Haider, S Naqeeb, Blair, Robert E, Deshpande, Laxmikant S, Sombati, Sompong, DeLorenzo, Robert J
Published in The Journal of pharmacology and experimental therapeutics (01.12.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2006)
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Journal Article
Calcium‐dependent Epileptogenesis in an In Vitro Model of Stroke‐induced “Epilepsy”
Sun, David A., Sombati, Sompong, Blair, Robert E., DeLorenzo, Robert J.
Published in Epilepsia (Copenhagen) (01.11.2002)
Published in Epilepsia (Copenhagen) (01.11.2002)
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Inhibition of Calcium/Calmodulin Kinase II Alpha Subunit Expression Results in Epileptiform Activity in Cultured Hippocampal Neurons
Churn, Severn B., Sombati, Sompong, Jakoi, Emma R., Sievert, Lawrence, DeLorenzo, Robert J.
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2000)
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Epileptogenesis causes an N-methyl-d-aspartate receptor/Ca2+-dependent decrease in Ca2+/calmodulin-dependent protein kinase II activity in a hippocampal neuronal culture model of spontaneous recurrent epileptiform discharges
Blair, Robert E., Sombati, Sompong, Churn, Severn B., DeLorenzo, Robert J.
Published in European journal of pharmacology (01.06.2008)
Published in European journal of pharmacology (01.06.2008)
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Journal Article
Aging is associated with elevated intracellular calcium levels and altered calcium homeostatic mechanisms in hippocampal neurons
Raza, Mohsin, Deshpande, Laxmikant S., Blair, Robert E., Carter, Dawn S., Sombati, Sompong, DeLorenzo, Robert J.
Published in Neuroscience letters (11.05.2007)
Published in Neuroscience letters (11.05.2007)
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Journal Article
Traumatic brain injury causes a long-lasting calcium (Ca2+)-plateau of elevated intracellular Ca levels and altered Ca2+ homeostatic mechanisms in hippocampal neurons surviving brain injury
Sun, David A., Deshpande, Laxmikant S., Sombati, Sompong, Baranova, Anya, Wilson, Margaret S., Hamm, Robert J., DeLorenzo, Robert J.
Published in The European journal of neuroscience (01.04.2008)
Published in The European journal of neuroscience (01.04.2008)
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