Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease
Schmidt, Amand F., Hunt, Nicholas B., Gordillo-Marañón, Maria, Charoen, Pimphen, Drenos, Fotios, Kivimaki, Mika, Lawlor, Deborah A., Giambartolomei, Claudia, Papacosta, Olia, Chaturvedi, Nishi, Bis, Joshua C., O’Donnell, Christopher J., Wannamethee, Goya, Wong, Andrew, Price, Jackie F., Hughes, Alun D., Gaunt, Tom R., Franceschini, Nora, Mook-Kanamori, Dennis O., Zwierzyna, Magdalena, Sofat, Reecha, Hingorani, Aroon D., Finan, Chris
Published in Nature communications (24.09.2021)
Published in Nature communications (24.09.2021)
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Journal Article
Association between Angiotensin Blockade and Incidence of Influenza in the United Kingdom
Chung, Sheng-Chia, Providencia, Rui, Sofat, Reecha
Published in New England Journal of Medicine (23.07.2020)
Published in New England Journal of Medicine (23.07.2020)
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Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis
López-López, José A, Sterne, Jonathan A C, Thom, Howard H Z, Higgins, Julian P T, Hingorani, Aroon D, Okoli, George N, Davies, Philippa A, Bodalia, Pritesh N, Bryden, Peter A, Welton, Nicky J, Hollingworth, William, Caldwell, Deborah M, Savović, Jelena, Dias, Sofia, Salisbury, Chris, Eaton, Diane, Stephens-Boal, Annya, Sofat, Reecha
Published in BMJ (Online) (28.11.2017)
Published in BMJ (Online) (28.11.2017)
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Journal Article
Selecting instruments for Mendelian randomization in the wake of genome-wide association studies
Swerdlow, Daniel I, Kuchenbaecker, Karoline B, Shah, Sonia, Sofat, Reecha, Holmes, Michael V, White, Jon, Mindell, Jennifer S, Kivimaki, Mika, Brunner, Eric J, Whittaker, John C, Casas, Juan P, Hingorani, Aroon D
Published in International journal of epidemiology (01.10.2016)
Published in International journal of epidemiology (01.10.2016)
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Journal Article
Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics
Gordillo-Marañón, María, Zwierzyna, Magdalena, Charoen, Pimphen, Drenos, Fotios, Chopade, Sandesh, Shah, Tina, Engmann, Jorgen, Chaturvedi, Nishi, Papacosta, Olia, Wannamethee, Goya, Wong, Andrew, Sofat, Reecha, Kivimaki, Mika, Price, Jackie F., Hughes, Alun D., Gaunt, Tom R., Lawlor, Deborah A., Gaulton, Anna, Hingorani, Aroon D., Schmidt, Amand F., Finan, Chris
Published in Nature communications (21.10.2021)
Published in Nature communications (21.10.2021)
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Journal Article
A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service
Kuan, Valerie, Denaxas, Spiros, Gonzalez-Izquierdo, Arturo, Direk, Kenan, Bhatti, Osman, Husain, Shanaz, Sutaria, Shailen, Hingorani, Melanie, Nitsch, Dorothea, Parisinos, Constantinos A, Lumbers, R Thomas, Mathur, Rohini, Sofat, Reecha, Casas, Juan P, Wong, Ian C K, Hemingway, Harry, Hingorani, Aroon D
Published in The Lancet. Digital health (01.06.2019)
Published in The Lancet. Digital health (01.06.2019)
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Data-driven identification of ageing-related diseases from electronic health records
Kuan, Valerie, Fraser, Helen C., Hingorani, Melanie, Denaxas, Spiros, Gonzalez-Izquierdo, Arturo, Direk, Kenan, Nitsch, Dorothea, Mathur, Rohini, Parisinos, Constantinos A., Lumbers, R. Thomas, Sofat, Reecha, Wong, Ian C. K., Casas, Juan P., Thornton, Janet M., Hemingway, Harry, Partridge, Linda, Hingorani, Aroon D.
Published in Scientific reports (03.02.2021)
Published in Scientific reports (03.02.2021)
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Journal Article
Screening strategies for atrial fibrillation: a systematic review and cost-effectiveness analysis
Welton, Nicky J, McAleenan, Alexandra, Thom, Howard Hz, Davies, Philippa, Hollingworth, Will, Higgins, Julian Pt, Okoli, George, Sterne, Jonathan Ac, Feder, Gene, Eaton, Diane, Hingorani, Aroon, Fawsitt, Christopher, Lobban, Trudie, Bryden, Peter, Richards, Alison, Sofat, Reecha
Published in Health technology assessment (Winchester, England) (01.05.2017)
Published in Health technology assessment (Winchester, England) (01.05.2017)
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Journal Article
Oral anticoagulants for primary prevention, treatment and secondary prevention of venous thromboembolic disease, and for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis and cost-effectiveness analysis
Sterne, Jonathan Ac, Bodalia, Pritesh N, Bryden, Peter A, Davies, Philippa A, López-López, Jose A, Okoli, George N, Thom, Howard Hz, Caldwell, Deborah M, Dias, Sofia, Eaton, Diane, Higgins, Julian Pt, Hollingworth, Will, Salisbury, Chris, Savović, Jelena, Sofat, Reecha, Stephens-Boal, Annya, Welton, Nicky J, Hingorani, Aroon D
Published in Health technology assessment (Winchester, England) (01.03.2017)
Published in Health technology assessment (Winchester, England) (01.03.2017)
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Journal Article
Circulating Apolipoprotein E Concentration and Cardiovascular Disease Risk: Meta-analysis of Results from Three Studies
Sofat, Reecha, Cooper, Jackie A, Kumari, Meena, Casas, Juan P, Mitchell, Jacqueline P, Acharya, Jayshree, Thom, Simon, Hughes, Alun D, Humphries, Steve E, Hingorani, Aroon D
Published in PLoS medicine (18.10.2016)
Published in PLoS medicine (18.10.2016)
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Atrial fibrillation epidemiology, disparity and healthcare contacts: a population-wide study of 5.6 million individuals
Chung, Sheng-Chia, Sofat, Reecha, Acosta-Mena, Dionisio, Taylor, Julie A, Lambiase, Pier D, Casas, Juan P, Providencia, Rui
Published in The Lancet regional health. Europe (01.08.2021)
Published in The Lancet regional health. Europe (01.08.2021)
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Journal Article
Neprilysin inhibition for pulmonary arterial hypertension: a randomized, double‐blind, placebo‐controlled, proof‐of‐concept trial
Hobbs, Adrian J., Moyes, Amie J., Baliga, Reshma S., Ghedia, Dipa, Ochiel, Rachel, Sylvestre, Yvonne, Doré, Caroline J., Chowdhury, Kashfia, Maclagan, Kate, Quartly, Harriet L., Sofat, Reecha, Smit, Angelique, Schreiber, Benjamin E., Coghlan, Gerry J., MacAllister, Raymond J.
Published in British journal of pharmacology (01.05.2019)
Published in British journal of pharmacology (01.05.2019)
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Journal Article
Performance of polygenic risk scores in screening, prediction, and risk stratification: secondary analysis of data in the Polygenic Score Catalog
Hingorani, Aroon D, Gratton, Jasmine, Finan, Chris, Schmidt, A Floriaan, Patel, Riyaz, Sofat, Reecha, Kuan, Valerie, Langenberg, Claudia, Hemingway, Harry, Morris, Joan K, Wald, Nicholas J
Published in BMJ medicine (17.10.2023)
Published in BMJ medicine (17.10.2023)
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Journal Article
Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip
Talmud, Philippa J., Drenos, Fotios, Shah, Sonia, Shah, Tina, Palmen, Jutta, Verzilli, Claudio, Gaunt, Tom R., Pallas, Jacky, Lovering, Ruth, Li, Kawah, Casas, Juan Pablo, Sofat, Reecha, Kumari, Meena, Rodriguez, Santiago, Johnson, Toby, Newhouse, Stephen J., Dominiczak, Anna, Samani, Nilesh J., Caulfield, Mark, Sever, Peter, Stanton, Alice, Shields, Denis C., Padmanabhan, Sandosh, Melander, Olle, Hastie, Claire, Delles, Christian, Ebrahim, Shah, Marmot, Michael G., Smith, George Davey, Lawlor, Debbie A., Munroe, Patricia B., Day, Ian N., Kivimaki, Mika, Whittaker, John, Humphries, Steve E., Hingorani, Aroon D.
Published in American journal of human genetics (13.11.2009)
Published in American journal of human genetics (13.11.2009)
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Journal Article
Modelling a two-stage adult population screen for autosomal dominant familial hypercholesterolaemia: cross-sectional analysis within the UK Biobank
Gratton, Jasmine, Humphries, Steve E, Schmidt, Amand Floriaan, Patel, Riyaz S, Sofat, Reecha, Finan, Chris, Morris, Joan K, Hingorani, Aroon D, Futema, Marta
Published in BMJ Public Health (01.12.2023)
Published in BMJ Public Health (01.12.2023)
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Journal Article
Bleeding in cardiac patients prescribed antithrombotic drugs: electronic health record phenotyping algorithms, incidence, trends and prognosis
Pasea, Laura, Chung, Sheng-Chia, Pujades-Rodriguez, Mar, Shah, Anoop D, Alvarez-Madrazo, Samantha, Allan, Victoria, Teo, James T, Bean, Daniel, Sofat, Reecha, Dobson, Richard, Banerjee, Amitava, Patel, Riyaz S, Timmis, Adam, Denaxas, Spiros, Hemingway, Harry
Published in BMC medicine (20.11.2019)
Published in BMC medicine (20.11.2019)
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An informatics consult approach for generating clinical evidence for treatment decisions
Lai, Alvina G, Chang, Wai Hoong, Parisinos, Constantinos A, Katsoulis, Michail, Blackburn, Ruth M, Shah, Anoop D, Nguyen, Vincent, Denaxas, Spiros, Davey Smith, George, Gaunt, Tom R, Nirantharakumar, Krishnarajah, Cox, Murray P, Forde, Donall, Asselbergs, Folkert W, Harris, Steve, Richardson, Sylvia, Sofat, Reecha, Dobson, Richard J B, Hingorani, Aroon, Patel, Riyaz, Sterne, Jonathan, Banerjee, Amitava, Denniston, Alastair K, Ball, Simon, Sebire, Neil J, Shah, Nigam H, Foster, Graham R, Williams, Bryan, Hemingway, Harry
Published in BMC medical informatics and decision making (12.10.2021)
Published in BMC medical informatics and decision making (12.10.2021)
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Journal Article
Role of NADPH Oxidase in Endothelial Ischemia/Reperfusion Injury in Humans
LOUKOGEORGAKIS, Stavros P, VAN DEN BERG, Merlijn J, SOFAT, Reecha, NITSCH, Dorothea, CHARAKIDA, Marietta, HAIYEE, Bu'Hussein, DE GROOT, Eric, MACALLISTER, Raymond J, KUIJPERS, Taco W, DEANFIELD, John E
Published in Circulation (New York, N.Y.) (01.06.2010)
Published in Circulation (New York, N.Y.) (01.06.2010)
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Disease coverage of human genome-wide association studies and pharmaceutical research and development
Gordillo-Marañón, María, Schmidt, Amand F., Warwick, Alasdair, Tomlinson, Chris, Ytsma, Cai, Engmann, Jorgen, Torralbo, Ana, Maclean, Rory, Sofat, Reecha, Langenberg, Claudia, Shah, Anoop D., Denaxas, Spiros, Pirmohamed, Munir, Hemingway, Harry, Hingorani, Aroon D., Finan, Chris
Published in Communications medicine (08.10.2024)
Published in Communications medicine (08.10.2024)
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