Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
Msaouel, Pavlos, Malouf, Gabriel G., Su, Xiaoping, Yao, Hui, Tripathi, Durga N., Soeung, Melinda, Gao, Jianjun, Rao, Priya, Coarfa, Cristian, Creighton, Chad J., Bertocchio, Jean-Philippe, Kunnimalaiyaan, Selvi, Multani, Asha S., Blando, Jorge, He, Rong, Shapiro, Daniel D., Perelli, Luigi, Srinivasan, Sanjana, Carbone, Federica, Pilié, Patrick G., Karki, Menuka, Seervai, Riyad N.H., Vokshi, Bujamin H., Lopez-Terrada, Dolores, Cheng, Emily H., Tang, Ximing, Lu, Wei, Wistuba, Ignacio I., Thompson, Timothy C., Davidson, Irwin, Giuliani, Virginia, Schlacher, Katharina, Carugo, Alessandro, Heffernan, Timothy P., Sharma, Padmanee, Karam, Jose A., Wood, Christopher G., Walker, Cheryl L., Genovese, Giannicola, Tannir, Nizar M.
Published in Cancer cell (11.05.2020)
Published in Cancer cell (11.05.2020)
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Journal Article
Loss of ARID1A Promotes Epithelial-Mesenchymal Transition and Sensitizes Pancreatic Tumors to Proteotoxic Stress
Tomihara, Hideo, Carbone, Federica, Perelli, Luigi, Huang, Justin K, Soeung, Melinda, Rose, Johnathon L, Robinson, Frederick S, Lissanu Deribe, Yonathan, Feng, Ningping, Takeda, Mitsunobu, Inoue, Akira, Poggetto, Edoardo Del, Deem, Angela K, Maitra, Anirban, Msaouel, Pavlos, Tannir, Nizar M, Draetta, Giulio F, Viale, Andrea, Heffernan, Timothy P, Bristow, Christopher A, Carugo, Alessandro, Genovese, Giannicola
Published in Cancer research (Chicago, Ill.) (15.01.2021)
Published in Cancer research (Chicago, Ill.) (15.01.2021)
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Radiation therapy and immunotherapy: what is the optimal timing or sequencing?
Aliru, Maureen L, Schoenhals, Jonathan E, Venkatesulu, Bhanu P, Anderson, Clark C, Barsoumian, Hampartsoum B, Younes, Ahmed I, K Mahadevan, Lakshmi S, Soeung, Melinda, Aziz, Kathryn E, Welsh, James W, Krishnan, Sunil
Published in Immunotherapy (01.02.2018)
Published in Immunotherapy (01.02.2018)
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Multi-site desmoplastic small round cell tumors are genetically related and immune-cold
Wu, Chia-Chin, Beird, Hannah C., Lamhamedi-Cherradi, Salah-Eddine, Soeung, Melinda, Ingram, Davis, Truong, Danh D., Porter, Robert W., Krishnan, Sandhya, Little, Latasha, Gumbs, Curtis, Zhang, Jianhua, Titus, Mark, Genovese, Giannicola, Ludwig, Joseph A., Lazar, Alexander J., Hayes-Jordan, Andrea, Futreal, P. Andrew
Published in NPJ precision oncology (04.04.2022)
Published in NPJ precision oncology (04.04.2022)
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Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy
Shapiro, Daniel D., Zacharias, Niki Millward, Tripathi, Durga N., Karki, Menuka, Bertocchio, Jean‐Philippe, Soeung, Melinda, He, Rong, Westerman, Mary E., Gao, Jianjun, Rao, Priya, Lam, Truong N. A., Jonasch, Eric, Perelli, Luigi, Cheng, Emily H., Carugo, Alessandro, Heffernan, Timothy P., Walker, Cheryl L., Genovese, Giannicola, Tannir, Nizar M., Karam, Jose A., Msaouel, Pavlos
Published in Clinical and translational medicine (01.05.2023)
Published in Clinical and translational medicine (01.05.2023)
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Journal Article
1498 Deploying spatial transcriptomics to inform on intratumoral heterogeneity in late-stage uveal melanoma leveraging advanced preclinical modeling and clinical samples
Srinivasan, Sanjana, Rose, Johnathon, Daniele, Joseph R, Peoples, Michael, He, Meng, Minelli, Rosalba, Terranova, Christopher, Liu, Chiu-Yi, Gay, Jason, Soeung, Melinda, Wani, Khalida, Perelli, Luigi, Loza, Dmitry, Feng, Ningping, Vellano, Christopher P, Marszalek, Joseph, Draetta, Giulio F, Futreal, Phillip Andrew, Woodman, Scott, Lazar, Alexander J, Heffernan, Timothy, Carugo, Alessandro, Genovese, Giannicola, Giuliani, Virginia
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
PD49-11 COMBINING NEDDYLATION INHIBITION WITH CHEMOTHERAPY TO TREAT RENAL MEDULLARY CARCINOMA
Shapiro, Daniel, Zacharias, Niki Millward, Tripathi, Durga, Bertocchio, Jean-Philippe, Soeung, Melinda, Rao, Priya, Walker, Cheryl, Genovese, Giannicola, Tannir, Nizar, Wood, Christopher, Karam, Jose, Msaouel, Pavlos
Published in The Journal of urology (01.09.2021)
Published in The Journal of urology (01.09.2021)
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PD43-01 PEVONEDISTAT SENSITIZES RENAL MEDULLARY CARCINOMA CELLS TO CARBOPLATIN BY DISRUPTING DNA DAMAGE REPAIR MECHANISMS
Shapiro, Daniel, Millward Zacharias, Niki, Tripathi, Durga, Bertocchio, Jean-Philippe, Soeung, Melinda, He, Rong, Gao, Jianjun, Rao, Priya, Lam, Truong, Perelli, Luigi, Carugo, Alessandro, Heffernan, Timothy, Walker, Cheryl, Genovese, Giannicola, Tannir, Nizar, Wood, Christopher, Karam, Jose, Msaouel, Pavlos
Published in The Journal of urology (01.05.2022)
Published in The Journal of urology (01.05.2022)
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Journal Article
High Throughput and Computational Repurposing for Neglected Diseases
Hernandez, Helen W., Soeung, Melinda, Zorn, Kimberley M., Ashoura, Norah, Mottin, Melina, Andrade, Carolina Horta, Caffrey, Conor R., de Siqueira-Neto, Jair Lage, Ekins, Sean
Published in Pharmaceutical research (01.02.2019)
Published in Pharmaceutical research (01.02.2019)
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Journal Article
p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
Carugo, Alessandro, Minelli, Rosalba, Sapio, Luigi, Soeung, Melinda, Carbone, Federica, Robinson, Frederick S., Tepper, James, Chen, Ziheng, Lovisa, Sara, Svelto, Maria, Amin, Samirkumar, Srinivasan, Sanjana, Del Poggetto, Edoardo, Loponte, Sara, Puca, Francesca, Dey, Prasenjit, Malouf, Gabriel G., Su, Xiaoping, Li, Liren, Lopez-Terrada, Dolores, Rakheja, Dinesh, Lazar, Alexander J., Netto, George J., Rao, Priya, Sgambato, Alessandro, Maitra, Anirban, Tripathi, Durga N., Walker, Cheryl L., Karam, Jose A., Heffernan, Timothy P., Viale, Andrea, Roberts, Charles W.M., Msaouel, Pavlos, Tannir, Nizar M., Draetta, Giulio F., Genovese, Giannicola
Published in Cancer cell (11.02.2019)
Published in Cancer cell (11.02.2019)
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Journal Article
Abstract 1247: Targeting neddylation in combination with cytotoxic chemotherapy for the treatment of renal medullary carcinoma
Shapiro, Daniel D., Zacharias, Niki Millward, Tripathi, Durga N., Bertocchio, Jean-Philippe, Soeung, Melinda, Rao, Priya, Walker, Cheryl L., Genovese, Giannicola, Tannir, Nizar M., Wood, Christopher G., Karam, Jose A., Msaouel, Pavlos
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
SMARCB1 regulates the hypoxic stress response in sickle cell trait
Soeung, Melinda, Perelli, Luigi, Chen, Ziheng, Dondossola, Eleonora, Ho, I-Lin, Carbone, Federica, Zhang, Li, Khan, Hania, Le, Courtney N, Zhu, Cihui, Peoples, Michael D, Feng, Ningping, Jiang, Shan, Zacharias, Niki Millward, Minelli, Rosalba, Shapiro, Daniel D, Deem, Angela K, Gao, Sisi, Cheng, Emily H, Lucchetti, Donatella, Walker, Cheryl L, Carugo, Alessandro, Giuliani, Virginia, Heffernan, Timothy P, Viale, Andrea, Tannir, Nizar M, Draetta, Giulio F, Msaouel, Pavlos, Genovese, Giannicola
Published in Proceedings of the National Academy of Sciences - PNAS (23.05.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (23.05.2023)
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Journal Article
Abstract 3853: T cell ferroptosis attenuates antitumor immune responses in sickle cell disease
Zhao, Zilong, Hu, Benxia, Deng, Yalan, Soeung, Melinda, Genovese, Giannicola, Li, Wenbo, Msaouel, Pavlos, Yang, Liuqing, Lin, Chunru
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis
Chen, Ziheng, Ho, I-Lin, Soeung, Melinda, Yen, Er-Yen, Liu, Jintan, Yan, Liang, Rose, Johnathon L., Srinivasan, Sanjana, Jiang, Shan, Edward Chang, Q., Feng, Ningping, Gay, Jason P., Wang, Qi, Wang, Jing, Lorenzi, Philip L., Veillon, Lucas J., Wei, Bo, Weinstein, John N., Deem, Angela K., Gao, Sisi, Genovese, Giannicola, Viale, Andrea, Yao, Wantong, Lyssiotis, Costas A., Marszalek, Joseph R., Draetta, Giulio F., Ying, Haoqiang
Published in Nature communications (17.04.2023)
Published in Nature communications (17.04.2023)
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Abstract B40: Perturbation of proteostasis is lethal in SMARCB1-deficient tumors
Soeung, Melinda, Carugo, Alessandro, Robinson, Frederick Scott, Minelli, Rosalba, Carbone, Federica, Maitra, Anirban, Viale, Andrea, Roberts, Charles W.M., Tannir, Nizar, Draetta, Giulio F., Genovese, Giannicola
Published in Cancer research (Chicago, Ill.) (01.10.2018)
Published in Cancer research (Chicago, Ill.) (01.10.2018)
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Abstract A062 Therapeutic targeting of the SAGA KAT module impairs MYCN-amplified neuroblastoma growth through reduction of the MYCN oncogenic gene expression program
Mabe, Nathaniel W., Malone, Clare F., Forman, Alexandra B., Alexe, Gabriela, Engel, Kathleen L., Chen, Ying-Jiun C., Soeung, Melinda, Salhotra, Silvi, Basanthakumar, Allen, Liu, Bin, Dent, Sharon YR, Stegmaier, Kimberly
Published in Cancer research (Chicago, Ill.) (05.09.2024)
Published in Cancer research (Chicago, Ill.) (05.09.2024)
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Journal Article
Abstract 1683: Ether phospholipids metabolism is a latent vulnerability for pancreatic cancer resistance
Chen, Ziheng, Ho, I-Lin, Soeung, Melinda, Yen, Er-Yen, Rose, Johnathon, Srinivasan, Sanjana, Deem, Angela, Gao, Sisi, Ying, Haoqiang, Draetta, Giulio
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma
Malone, Clare F, Mabe, Nathaniel W, Forman, Alexandra B, Alexe, Gabriela, Engel, Kathleen L, Chen, Ying-Jiun C, Soeung, Melinda, Salhotra, Silvi, Basanthakumar, Allen, Liu, Bin, Dent, Sharon Y R, Stegmaier, Kimberly
Published in Science advances (31.05.2024)
Published in Science advances (31.05.2024)
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Journal Article
Association of High-Intensity Exercise with Renal Medullary Carcinoma in Individuals with Sickle Cell Trait: Clinical Observations and Experimental Animal Studies
Shapiro, Daniel D, Soeung, Melinda, Perelli, Luigi, Dondossola, Eleonora, Surasi, Devaki Shilpa, Tripathi, Durga N, Bertocchio, Jean-Philippe, Carbone, Federica, Starbuck, Michael W, Van Alstine, Michael L, Rao, Priya, Katz, Matthew H G, Parker, Nathan H, Shah, Amishi Y, Carugo, Alessandro, Heffernan, Timothy P, Schadler, Keri L, Logothetis, Christopher, Walker, Cheryl L, Wood, Christopher G, Karam, Jose A, Draetta, Giulio F, Tannir, Nizar M, Genovese, Giannicola, Msaouel, Pavlos
Published in Cancers (30.11.2021)
Published in Cancers (30.11.2021)
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Abstract 1758: Chromosome 3 copy number loss alone drives tumor evolution to aggressive disease in uveal melanoma
Srinivasan, Sanjana, Rose, Johnathon, Minelli, Rosalba, Terranova, Christopher, Shah, Parth, Daniele, Joseph R., Peoples, Michael, He, Meng, Liu, Chiu-Yi, Gay, Jason, Soeung, Melinda, Soni, Sanjay, Wang, Fangyang, Bristow, Christopher, Wani, Khalida, Perelli, Luigi, Loza, Dmitry, Feng, Ningping, Tarabichi, Maxime, Van Loo, Peter, Futreal, Andrew, Woodman, Scott, Lazar, Alexander, Vellano, Christopher P., Marszalek, Joseph, Draetta, Giulio F., Heffernan, Timothy, Carugo, Alessandro, Genovese, Giannicola, Giuliani, Virginia
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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