Translation control of the immune checkpoint in cancer and its therapeutic targeting
Xu, Yichen, Poggio, Mauro, Jin, Hyun Yong, Shi, Zhen, Forester, Craig M., Wang, Ying, Stumpf, Craig R., Xue, Lingru, Devericks, Emily, So, Lomon, Nguyen, Hao G., Griselin, Alice, Gordan, John D., Umetsu, Sarah E, Reich, Siegfried H., Worland, Stephen T., Asthana, Saurabh, Barna, Maria, Webster, Kevin R., Cunningham, John T., Ruggero, Davide
Published in Nature medicine (01.02.2019)
Published in Nature medicine (01.02.2019)
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RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions
Schwerk, Johannes, Soveg, Frank W., Ryan, Andrew P., Thomas, Kerri R., Hatfield, Lauren D., Ozarkar, Snehal, Forero, Adriana, Kell, Alison M., Roby, Justin A., So, Lomon, Hyde, Jennifer L., Gale, Michael, Daugherty, Matthew D., Savan, Ram
Published in Nature immunology (01.12.2019)
Published in Nature immunology (01.12.2019)
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Journal Article
Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor
Fruman, David A, Janes, Matthew R, Limon, Jose J, So, Lomon, Chen, Jing, Lim, Raymond J, Chavez, Melissa A, Vu, Collin, Lilly, Michael B, Mallya, Sharmila, Ong, S Tiong, Konopleva, Marina, Martin, Michael B, Ren, Pingda, Liu, Yi, Rommel, Christian
Published in Nature medicine (01.02.2010)
Published in Nature medicine (01.02.2010)
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Journal Article
The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes
So, Lomon, Lee, Jongdae, Palafox, Miguel, Mallya, Sharmila, Woxland, Chaz G, Arguello, Meztli, Truitt, Morgan L, Sonenberg, Nahum, Ruggero, Davide, Fruman, David A
Published in Science signaling (31.05.2016)
Published in Science signaling (31.05.2016)
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Journal Article
Germline SAMD9L truncation variants trigger global translational repression
Allenspach, Eric J, Soveg, Frank, Finn, Laura S, So, Lomon, Gorman, Jacquelyn A, Rosen, Aaron B I, Skoda-Smith, Suzanne, Wheeler, Marsha M, Barrow, Kaitlyn A, Rich, Lucille M, Debley, Jason S, Bamshad, Michael J, Nickerson, Deborah A, Savan, Ram, Torgerson, Troy R, Rawlings, David J
Published in The Journal of experimental medicine (03.05.2021)
Published in The Journal of experimental medicine (03.05.2021)
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Journal Article
mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition
Limon, Jose J, So, Lomon, Jellbauer, Stefan, Chiu, Honyin, Corado, Juana, Sykes, Stephen M, Raffatellu, Manuela, Fruman, David A
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2014)
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Journal Article
Resistance to mTOR kinase inhibitors in lymphoma cells lacking 4EBP1
Mallya, Sharmila, Fitch, Briana A, Lee, J Scott, So, Lomon, Janes, Matthew R, Fruman, David A
Published in PloS one (21.02.2014)
Published in PloS one (21.02.2014)
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Journal Article
Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and Type III Interferons
Forero, Adriana, Ozarkar, Snehal, Li, Hongchuan, Lee, Chia Heng, Hemann, Emily A., Nadjsombati, Marija S., Hendricks, Matthew R., So, Lomon, Green, Richard, Roy, Chandra N., Sarkar, Saumendra N., von Moltke, Jakob, Anderson, Stephen K., Gale, Michael, Savan, Ram
Published in Immunity (Cambridge, Mass.) (17.09.2019)
Published in Immunity (Cambridge, Mass.) (17.09.2019)
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Journal Article
Regulatory T cells suppress CD4+ effector T cell activation by controlling protein synthesis
So, Lomon, Obata-Ninomiya, Kazushige, Hu, Alex, Muir, Virginia S, Takamori, Ayako, Song, Jing, Buckner, Jane H, Savan, Ram, Ziegler, Steven F
Published in The Journal of experimental medicine (06.03.2023)
Published in The Journal of experimental medicine (06.03.2023)
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Journal Article
A non-canonical mechanism of antiviral activity of Oligoadenylate Synthetase 1
Harioudh, Munesh, Perez, Joseph, Chong, Zhenlu, Nair, Sharmila, So, Lomon, McCormick, Kevin, Ghosh, Arundhati, Shao, Lulu, Srivastava, Rashmi, Soveg, Frank, Ebert, Thomas, Atianand, Maninjay, Hornung, Veit, Savan, Ram, Diamond, Michael, Sarkar, Saumendra
Published in The Journal of immunology (1950) (01.05.2024)
Published in The Journal of immunology (1950) (01.05.2024)
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Journal Article
Oligoadenylate synthetase 1 displays dual antiviral mechanisms in driving translational shutdown and protecting interferon production
Harioudh, Munesh K., Perez, Joseph, Chong, Zhenlu, Nair, Sharmila, So, Lomon, McCormick, Kevin D., Ghosh, Arundhati, Shao, Lulu, Srivastava, Rashmi, Soveg, Frank, Ebert, Thomas S., Atianand, Maninjay K., Hornung, Veit, Savan, Ram, Diamond, Michael S., Sarkar, Saumendra N.
Published in Immunity (Cambridge, Mass.) (12.03.2024)
Published in Immunity (Cambridge, Mass.) (12.03.2024)
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Journal Article
The canonical antiviral protein oligoadenylate synthetase 1 elicits antibacterial functions by enhancing IRF1 translation
Harioudh, Munesh K., Perez, Joseph, So, Lomon, Maheshwari, Mayank, Ebert, Thomas S., Hornung, Veit, Savan, Ram, Rouf Banday, A., Diamond, Michael S., Rathinam, Vijay A., Sarkar, Saumendra N.
Published in Immunity (Cambridge, Mass.) (13.08.2024)
Published in Immunity (Cambridge, Mass.) (13.08.2024)
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Journal Article
Quantitative proteomic and genetic analyses of the schizophrenia susceptibility factor dysbindin identify novel roles of the biogenesis of lysosome-related organelles complex 1
Gokhale, Avanti, Larimore, Jennifer, Werner, Erica, So, Lomon, Moreno-De-Luca, Andres, Lese-Martin, Christa, Lupashin, Vladimir V, Smith, Yoland, Faundez, Victor
Published in The Journal of neuroscience (14.03.2012)
Published in The Journal of neuroscience (14.03.2012)
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Journal Article
Oligoadenylate Synthetase 1 enhances DNA sensor cGAS translation to mediate WNV antiviral activity
Perez, Joseph, Harioudh, Munesh K., So, Lomon, Nair, Sharmila, McCormick, Kevin, Ghosh, Arundhati, Shao, Lulu, Srivastava, Rashmi, Ebert, Thomas, Atianand, Maninjay, Hornung, Veit, Diamond, Michael S., Savan, Ram, Sarkar, Saumendra N.
Published in The Journal of immunology (1950) (01.05.2020)
Published in The Journal of immunology (1950) (01.05.2020)
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Journal Article
Reciprocal effects of rab7 deletion in activated and neglected T cells
Roy, Saurabh Ghosh, Stevens, Michael W., So, Lomon, Edinger, Aimee L.
Published in Autophagy (01.07.2013)
Published in Autophagy (01.07.2013)
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Journal Article
Selective Inhibition of Phosphoinositide 3-Kinase p110α Preserves Lymphocyte Function
So, Lomon, Yea, Sung Su, Oak, Jean S., Lu, Mengrou, Manmadhan, Arun, Ke, Qiao Han, Janes, Matthew R., Kessler, Linda V., Kucharski, Jeff M., Li, Lian-Sheng, Martin, Michael B., Ren, Pingda, Jessen, Katti A., Liu, Yi, Rommel, Christian, Fruman, David A.
Published in The Journal of biological chemistry (22.02.2013)
Published in The Journal of biological chemistry (22.02.2013)
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